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Charleston, SC 5+ Bedroom Vacation Rentals

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166 rentals found
Mint Julep | Largest Private Pool Downto...
4.8
(30)

Permit Number: 05932The Space: Step into a world of opulence and relaxation at The Mint Julep House, where every detail has been meticulously curated for an extraordinary stay. This two-story residence, freshly refreshed and impeccably furnished...

  • Charleston
  • 6 Bedrooms
  • 5 Bathrooms
  • Sleeps 12
The Fish! Most Unique High-End Luxury Re...
4.8
(18)

$250 Beach gear credit supplied with all new reservations! *Applies to 3-14 nighttime stays only* BR 1: 1 King, BR 2: 1 King, BR 3: 1 King, BR 4:1 King, BR 5: 4 Twins; Sleeps 12, Private Pool, High-End Unique Home, Screen Porch, Gas grille, Folly...

  • Charleston
  • 5 Bedrooms
  • 4 Bathrooms
  • Sleeps 12
Brand NEW! 5BR/5BA Home, Perfect for Gro...

26 Bee Street features two distinct units in Charleston's charming Cannonborough/Elliotborough neighborhood. This vibrant property includes five bedrooms and five bathrooms across both units, each delightfully restored to showcase historic appeal...

  • Charleston
  • 5 Bedrooms
  • 5 Bathrooms
  • Sleeps 10
The Quad at 493 - 4 Suites - Right on Ki...

Permit Number: 004141The Space: Welcome to 493 Luxury Suites! These delightfully appointed units are found on the second floor of a historic building on King Street (above Sewing Down South, as seen on “Southern Charm”).Step into the building...

  • Charleston
  • 8 Bedrooms
  • 8 Bathrooms
  • Sleeps 24
The Sterling | Newly Renovated 5BR DT, W...

Summary:Welcome to your Charleston escape, a gorgeous 5-bedroom getaway where timeless craftsmanship meets modern comfort. With gleaming pine floors, intricate moldings, and extravagant design details throughout, this home offers the ideal blend of...

  • Charleston
  • 5 Bedrooms
  • 5 Bathrooms
  • Sleeps 11
Downtown Duplex - Coming St - Sleeps 20

Feel the timeless appeal of Charleston’s historic peninsula, the Holy City. Stay just mins. from MUSC, the College of Charleston, and the vibrant shopping, dining, and nightlife of King Street. From this ideally located downtown home, you’ll be...

  • Charleston
  • 6 Bedrooms
  • 4 Bathrooms
  • Sleeps 16
Casa Zoë | Royal House – Charleston...

Summary:The Royal House is Charleston’s ultimate group escape: a dual-unit Casa Zoë mansion that blends grandeur, design, and independence. With 8 bedrooms, 8 baths, and separate living quarters, it offers shared elegance with private...

  • Charleston
  • 8 Bedrooms
  • 10 Bathrooms
  • Sleeps 16
Stylish 5BR/5BA Downtown Retreat - Walk ...

Summary:Stay in this freshly remodeled 5-bedroom, 5-bathroom downtown getaway accommodating up to 12 guests. Featuring open concept living areas, a entirely equipped kitchen, extravagant king beds, and off-street parking. Just one block from King...

  • Charleston
  • 5 Bedrooms
  • 5 Bathrooms
  • Sleeps 12
Sleeps 16 | Pet-Friendly 2-Unit w/ Backy...
5.0
(1)

Sleeps up to 16! This modern, freshly remodeled home consists of 2 sizable apartments, rentable separately or together. You have a private backyard to relax/dine with a wide umbrella. Wood floors sit beneath exposed beams, w/ stainless steel...

  • Charleston
  • 6 Bedrooms
  • 4 Bathrooms
  • Sleeps 16
Guesthouse Charleston: WEST (242 B & C)
4.9
(18)

West 242 B and 242 C are two impressive standalone homes located in the heart of Charleston's vibrant Cannonborough/Elliotborough neighborhood, just two blocks from historic King Street. This prime location offers simple access to Charleston's best...

  • Charleston
  • 8 Bedrooms
  • 6 Bathrooms
  • Sleeps 16
Private Pool & Historic Home ‘Summer H...

Summary:A short walk to famed King Street, 'The Summer Haze' is a private Charleston home, with private pool! Renovated with modern amenities, experience the appeal of a traditional Charleston home, with comfortable bedrooms & en suite bathrooms...

  • Charleston
  • 6 Bedrooms
  • 6 Bathrooms
  • Sleeps 14
Historic Whole Home- Private Heated Pool...

Summary:Welcome to Your Private Oasis in Historic Charleston!Feel the ideal fusion of Historic appeal and modern luxury at this five-bedroom, three-and-a-half-bathroom Historic Home. Located just blocks from the iconic King Street, this residence...

  • Charleston
  • 5 Bedrooms
  • 3 Bathrooms
  • Sleeps 14
The Monroe | 5BR - Voted Best of Charles...
4.9
(22)

Summary:Stay at The Monroe on Spring, a entirely refreshed 1885 Charleston manor voted Finest of Charleston. Blending historic grandeur with modern luxury, this 5-bedroom getaway features extravagant interiors and sprawling porches ideal for calming...

  • Charleston
  • 5 Bedrooms
  • 5 Bathrooms
  • Sleeps 16
The Bogard Duo 6 Bed 6 Bath

Recently-modernized six bedroom historic home in the trendy, laid-back Cannonborough neighborhood close to great eateries & historical sights.This classic Charleston home is made up of two units A&B, this is the listing for both units. The entire...

  • Charleston
  • 6 Bedrooms
  • 6 Bathrooms
  • Sleeps 12
The Rose Charleston | Perfect for Large ...

Summary:Escape to The Rose, a elegantly refreshed 2-story Charleston classic in the heart of downtown. With 6 bedrooms and 4 bathrooms, this modren getaway is ideal for huge groups seeking both space and comfort. Unwind in the inviting living room...

  • Charleston
  • 6 Bedrooms
  • 4 Bathrooms
  • Sleeps 16
Heart of Downtown - All En-suites baths!
4.6
(5)

Summary:Giant groups looking for a authentic, welcoming home away from home in downtown Charleston look no further! Our newly-modernized historic home offers three separate 3 bedroom/3 bath units housed within the same home for a total of 9...

  • Charleston
  • 9 Bedrooms
  • 9 Bathrooms
  • Sleeps 16
Oikos - 19 Bedrooms in Downtown Charlest...

Permit Number: 05084,05085,05086,05087The Space: Welcome to your ultimate group hideaway! This broad 4-unit, 19-bedroom listing is ideal for huge groups, corporate retreats, or multi-family vacations. Designed for comfort and convenience, this...

  • Charleston
  • 19 Bedrooms
  • 15 Bathrooms
  • Sleeps 38
The Waltz | Great for Large Groups
4.7
(9)

Permit Number: 05635,36The Space: Our roomy 2nd and 3rd floor condo, ‘The Waltz’, is ideal for enormous groups with 5 bedrooms and 4 full baths. It is in a prime location on Spring Street. Parking will not be an issue with complimentary off...

  • Charleston
  • 5 Bedrooms
  • 4 Bathrooms
  • Sleeps 11