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Charleston, SC 5+ Bedroom Vacation Rentals

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156 rentals found
Cocktail Club | 4 Redesigned Suites

Permit Number: 05591The Space: Appreciate gracious Southern living in our roomy 8 BR home. The home is divided into four gorgeously designed 2 BR units, making this property ideal for sizable groups. Each unit has been thoughtfully decorated to...

  • Charleston
  • 8 Bedrooms
  • 4 Bathrooms
  • Sleeps 17
Magnificent 1852 Mansion, Center Histori...

Summary:Savor a refined antebellum experience with amenities both new and crafted from reclaimed pieces of Charleston history. The bathroom is tiled using the original 1851 slate from Vermont with cypress ship-lap wood walls and heart pine...

  • Charleston
  • 9 Bedrooms
  • 6 Bathrooms
  • Sleeps 16
6 Bedrooms! One Block to King Street!

Summary:Welcome to your Charleston gathering home, a six-bedroom property just one block from King Street that offers space, character, and plenty of outdoor appeal. Ideal for huge families or groups who want walk-ability, historic details, and room...

  • Charleston
  • 6 Bedrooms
  • 4 Bathrooms
  • Sleeps 14
Six on Cannon | 6BR Charleston Home + Pa...

Summary:Welcome to Six on Cannon, a cavernous 6 bedroom 2 bathroom home ideally suited for families, friends, or get-togethers who want room, style, and downtown convenience together. Recently furnished and thoughtfully arranged, it gives you all...

  • Charleston
  • 6 Bedrooms
  • 2 Bathrooms
  • Sleeps 16
The Madison Compound- Entire Charleston ...

Encompass yourself in the history of Charleston by staying in this freshly refreshed 1890`s single home. The Madison Compound offers guests all the aesthetic features of a Charleston Single House from it huge Piazzas, private roof top deck and...

  • Charleston
  • 6 Bedrooms
  • 7 Bathrooms
  • Sleeps 16
New design & construction, 6 Bed, 6 EnSu...

Welcome to 183 Saint Philip Street, your chic haven in the heart of Charleston! This new construction offers a prime location, placing you steps away from the city's vibrant attractions & best eateries. Each bedroom features 55" Samsung TVs ...

  • Charleston
  • 6 Bedrooms
  • 6 Bathrooms
  • Sleeps 16
The Pineapple Pad | EastBay Historic Dis...

Summary:Welcome to your Charleston sanctuary where historic appeal meets roomy luxury. This 5-bedroom getaway offers a generous 3,000 square feet of gorgeously appointed space. Ideal for families or groups who want charming design, room to spread...

  • Charleston
  • 5 Bedrooms
  • 4 Bathrooms
  • Sleeps 16
Downtown Charleston Gem | Walk Everywher...

Summary:Welcome to The Lavender???? & Sage Suites ???? a handsomely restored 6BR 6.5BA home that pairs modern luxury with timeless Southern appeal. Located in the heart of downtown Charleston, you're just steps from the city's best eateries...

  • Charleston
  • 6 Bedrooms
  • 6 Bathrooms
  • Sleeps 12
8 Bedroom - Close to King Street - with ...

Feel the timeless appeal of Charleston’s historic peninsula, the Holy City. Stay just mins. from MUSC, the College of Charleston, and the vibrant shopping, dining, and nightlife of King Street. From this ideally located downtown home, you’ll be...

  • Charleston
  • 8 Bedrooms
  • 4 Bathrooms
  • Sleeps 16
THE DELPHINE Luxury Downtown Charleston ...

Welcome to your beautiful getaway in the heart of Downtown Charleston! Located in the handsome Cannonborough/Elliotborough District, this charming home constructed in 2022 is just steps from King Street’s top eateries, stores, and nightlife...

  • Charleston
  • 5 Bedrooms
  • 3 Bathrooms
  • Sleeps 12
The Gardenia House | Sleeps 15 | Multi-U...

Summary:Welcome to the Gardenia House in the Preserve, a distinguished luxury residence located in the heart of downtown Charleston. This handsome property offers two exclusive suites within a cavernous layout of 7 bedrooms and 7 full baths, making...

  • Charleston
  • 7 Bedrooms
  • 7 Bathrooms
  • Sleeps 14
The Waltz | Great for Large Groups

Permit Number: 05635The Space: Our roomy 2nd and 3rd floor condo, ‘The Waltz’, is ideal for sizable groups with 5 bedrooms and 4 full baths. It is in a prime location on Spring Street. Parking will not be an issue with complimentary off street...

  • Charleston
  • 5 Bedrooms
  • 4 Bathrooms
  • Sleeps 11
Downtown Historic Home Close to Neighbor...

Summary:Welcome to this vibrant downtown getaway! Originally constructed in 1905 and newly refreshed, this colorful home blends historic appeal with modern comfort. With eight uniquely styled bedrooms and eight handsomely updated bathrooms, there's...

  • Charleston
  • 8 Bedrooms
  • 4 Bathrooms
  • Sleeps 16
Fantastic Private Quarters in Heart of D...

Summary:Here you can live by calming both indoors and outdoors.The Space:Summons the expression of really refined Ante-Bellum experience with all modern amenities. In the kitchen appreciate the timeless La CornueFe gas oven and cooktop range from...

  • Charleston
  • 5 Bedrooms
  • 3 Bathrooms
  • Sleeps 10
8BR-Spring Street Retreat ~ 2 Full Homes...

Welcome to the Holy City, and the historic southern appeal of the Charleston peninsula. Our Vacation Rental By Owner is located in handsome downtown Charleston and just mins. away from MUSC, the College of Charleston, and King Street’s shopping...

  • Charleston
  • 8 Bedrooms
  • 6 Bathrooms
  • Sleeps 16
The Lookout- hot tub, heated pool, with ...

Welcome to life in the Lowcountry at The Lookout! The design of this home embodies the natural beauty of life on the water with comfort and style. Heated pool just installed! Great place to cool off year round- close to the outdoor TV...

  • Charleston
  • 5 Bedrooms
  • 6 Bathrooms
  • Sleeps 12
The Inns | 5bd Downtown Luxury Suite w. ...

Summary:Located on appealing Spring Street, this newly refreshed 5-bedroom, 3-bath getaway ideally blends Charleston’s historic elegance with modern luxury. Freshly painted and outfitted with new beds and linens, the home features bright, inviting...

  • Charleston
  • 5 Bedrooms
  • 3 Bathrooms
  • Sleeps 13
10BR/10BA Downtown Home - Steps to King ...

Summary:Discover this massive 10-bedroom, 10-bathroom getaway in downtown Charleston, accommodating up to 22 guests. Luxuriate in open living spaces, a entirely equipped kitchen, and king-size beds throughout. With off-street parking, modern...

  • Charleston
  • 10 Bedrooms
  • 10 Bathrooms
  • Sleeps 24