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5+ Bedroom Vacation Rentals

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296 rentals found
New Renovation - 5 Beds/5 Baths - 1 Bloc...

About this spaceALL NEW, entirely modernized home one block from King Street- 2 rooms w/ king beds, 3 rooms w/ queen beds, living room w/ king pullout couch- Flexible check-in / out times- Multiple private outdoor patios- 2 off-street parking spots...

  • Charleston
  • 5 Bedrooms
  • 5 Bathrooms
  • Sleeps 12
Sunset Point - Stunning Luxury

This oceanfront, bespoke constructed 6 bedroom/8.5 bathroom home features 7,000 square feet of pure elegance. Each room was professionally designed and no expense was spared. The attention to detail includes stone floor throughout the first floor...

  • Isle of Palms
  • 6 Bedrooms
  • 8 Bathrooms
  • Sleeps 12
Where Tranquility Blooms | Blossoms on C...

Permit Number: 07328The Space: Welcome to Blossoms on Cannon, a handsomely restored two story Charleston home designed for comfort, connection, and memorable group stays in the heart of downtown! There will be work taking place at the back of the...

  • Charleston
  • 5 Bedrooms
  • 4 Bathrooms
  • Sleeps 11
Stunning Wild Dunes Home-- Fire Pit, Hot...

Welcome to 10 Yacht Harbor, your dream hideaway in Wild Dunes Resort on the striking Isle of Palms. This newly constructed 5-bedroom vacation rental combines extravagant comfort with the casual appeal of southern coastal living. Just a short 25-min...

  • Isle of Palms
  • 5 Bedrooms
  • 4 Bathrooms
  • Sleeps 12
Charming Downtown 6BR - Steps to King St...

Summary:Stay in this roomy 6BR/6BA Charleston getaway, just steps from King Street. Each bedroom offers a king bed and ensuite bath, giving guests both privacy and comfort. With two full kitchens, multiple living areas, and off-street parking for 4...

  • Charleston
  • 6 Bedrooms
  • 6 Bathrooms
  • Sleeps 14
Private Pool + Rooftop Ocean Views

All Decked Out – Relaxed Coastal Luxury with Rooftop Ocean VistasWelcome to All Decked Out, a charmingly designed Isle of Palms getaway where laid-back coastal living, broad outdoor spaces, and elevated beach home comfort create the ideal setting...

  • Isle of Palms
  • 5 Bedrooms
  • 5 Bathrooms
  • Sleeps 12
Guesthouse Charleston: Historic downtown...

Two handsome adjoining apartments offering a total of 5 bedrooms, 5 bathrooms, 2 full kitchens, and 2 cavernous living rooms, making them ideal for bigger groups or families seeking both space and comfort. Located just one block from King Street in...

  • Charleston
  • 5 Bedrooms
  • 5 Bathrooms
  • Sleeps 14
Classic Style Sullivan's Island house - ...

Please note that every reservation will be required to sign an independent vacation rental agreement.Welcome to 2820 Ion Ave! Escape to Sullivan's Island in this gorgeous vacation home that's only 1.5 blocks from the beach! This charmingly classic...

  • Sullivans Island
  • 6 Bedrooms
  • 3 Bathrooms
  • Sleeps 12
1 Pelican- Easy Walk to Beach & Communit...

All 2026 reservation will receive $250 credit toward beach gear units with VayK Life! *3-21 nights onlyWelcome to your ideal Isle of Palms hideaway! Located in a peaceful cul-de-sac within Wild Dunes Resort, 1 Pelican Bay is a charmingly appointed...

  • Isle of Palms
  • 5 Bedrooms
  • 3 Bathrooms
  • Sleeps 10
Brand New Custom Home~ Oceanfront, Pool,...

Step into unparalleled coastal luxury at this newly constructed, professionally designed oceanfront 5-bedroom home—one of Isle of Palms' premier vacation units. Sandcastle, 2704 Palm Blvd., has every detail crafted for high-end living, from the...

  • Isle of Palms
  • 5 Bedrooms
  • 6 Bathrooms
  • Sleeps 10
Historic Charm | The Bee & Blossom

Permit Number: 07286The Space: Welcome to The Bee and Blossom, a delightfully reimagined historic 6-bedroom, 6.5-bath home in the laid-back Radcliffborough neighborhood, thoughtfully designed for groups of up to twelve guests!Spanning three roomy...

  • Charleston
  • 6 Bedrooms
  • 6 Bathrooms
  • Sleeps 12
The OakTree | Stylish Bohemian Downtown ...

Summary:Welcome to The OakTree, your boho-chic haven in the heart of downtown Charleston, where artistic flair meets generous space. Ideal for enormous groups, families, or creative retreats, this 7-bedroom home offers character, comfort, and close...

  • Charleston
  • 7 Bedrooms
  • 7 Bathrooms
  • Sleeps 16
Rare French Quarter Escape, Sleeps 16 w....

Summary:Located in the heart of the French Quarter and draped in history, this private, secure 3,300 sq. ft. luxury getaway comfortably sleeps 16 guests with 5 cavernous bedrooms, dual master suites, ensuite bathrooms, and upgraded luxury amenities...

  • Charleston
  • 5 Bedrooms
  • 4 Bathrooms
  • Sleeps 16
Pool, Beach Access, Walk to Town, Pet ok...

Make everlasting memories with you and your whole family on your next vacation at 808 Ocean Boulevard. 808 Ocean Boulevard is a striking private 6 bedroom 6 bath home located oceanfront on the southern side of the Isle of Palms. Just mins. walk from...

  • Isle of Palms
  • 6 Bedrooms
  • 7 Bathrooms
  • Sleeps 14
Charleston Charm: Renovated 4BR House wi...

Summary:Attractively remodeled downtown Charleston home available as a 30+ day furnished executive rental. Located just mins. from King Street dining/shopping and an painless walk to Colonial Lake, this bright two-story residence blends classic...

  • Charleston
  • 5 Bedrooms
  • 4 Bathrooms
  • Sleeps 8
5BR Spring Street Duplex - Walk to King ...

Feel the timeless appeal of Charleston’s historic peninsula, the Holy City. Stay just mins. from MUSC, the College of Charleston, and the vibrant shopping, dining, and nightlife of King Street. From this ideally located downtown home, you’ll be...

  • Charleston
  • 5 Bedrooms
  • 3 Bathrooms
  • Sleeps 10
Rosemary House - C | Perfect for Wedding...

Summary:Located above The Rutledge Room, Unit C at The Rosemary House is a 5 bed, 5 bath penthouse with designer furnishings and refreshed amenities. The layout is constructed for a crowd, with an open kitchen and living room where your group can...

  • Charleston
  • 5 Bedrooms
  • 5 Bathrooms
  • Sleeps 10
Spacious, Family Beach Home! Ping Pong, ...

Welcome to #32 - 41st Ave! This cavernous, modernized five-bedroom beach home has a modern look, comfortable feel, and is ideal for your family to savor a beach vacation! Property Highlights- 3 Living Areas - All with Intelligent TVs- Free High...

  • Isle of Palms
  • 5 Bedrooms
  • 3 Bathrooms
  • Sleeps 10