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5+ Bedroom Vacation Rentals

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299 rentals found
1 Block to King | CHS Best Coffee and Re...

The Space: Welcome to your historic Charleston getaway, a elegantly restored 1820 residence combining timeless character with modern comfort in the heart of the city!This property offers two private units, one upstairs and one downstairs, each with...

  • Charleston
  • 6 Bedrooms
  • 5 Bathrooms
  • Sleeps 15
New design & construction, 6 Bed, 6 EnSu...

Welcome to 183 Saint Philip Street, your chic haven in the heart of Charleston! This new construction offers a prime location, placing you steps away from the city's vibrant attractions & best eateries. Each bedroom features 55" Samsung TVs ...

  • Charleston
  • 6 Bedrooms
  • 6 Bathrooms
  • Sleeps 16
Charleston Abode | Downtown, 1 Block fro...

Summary:Welcome to Charleston Abode, a luminous 2-bedroom getaway just one block from King Street where historic appeal meets modern comfort. Designed for couples or modest groups, this home offers airy interiors, fresh details, and rare outdoor...

  • Charleston
  • 6 Bedrooms
  • 4 Bathrooms
  • Sleeps 14
Private Pool + Rooftop Deck + Beach Gear...

A beach path sits a short walk down the street from 118 Charleston IOP Beachhouse, on the south end of Isle of Palms near Breach Inlet. Chairs, umbrellas, and a beach wagon are already in the home, so getting down to the sand for the day takes one...

  • Isle of Palms
  • 7 Bedrooms
  • 6 Bathrooms
  • Sleeps 14
3 47th Avenue by AvantStay | Oceanfront ...

Welcome to 3 47th Avenue, where gorgeous architecture meets modern design. This roomy getaway invites you to indulge in the ideal blend of luxury and comfort.Marvel at the unique private pool, boasting an in-water sitting area for unparalleled...

  • Isle of Palms
  • 6 Bedrooms
  • 7 Bathrooms
  • Sleeps 12
Ocean Views + Private Pool + Resort Amen...

3301 Palm Blvd by Wild Dunes6 Bedrooms | 5 Bathrooms | Sleeps 14 | Ocean View ____________________________________Welcome to 3301 Palm, a freshly remodeled, impressive 3920sq. ft. luxury getaway within Isle of Palms’ exclusive to Wild Dunes...

  • Isle of Palms
  • 5 Bedrooms
  • 5 Bathrooms
  • Sleeps 14
Thomas Waring House | Unit A | Sleeps 11

Summary:Welcome to Thomas Waring House-Suite A at The Preserve, a historic and award-winning residence that offers a unique blend of appeal and modern convenience. This luxury suite in downtown Charleston is comprised of 5 bedrooms and 5.5...

  • Charleston
  • 5 Bedrooms
  • 5 Bathrooms
  • Sleeps 11
East 42 A & B - Entire Ground Floor, 2 U...

East 42 A & B is the combined listing for the two homes below. These two delightful homes can be connected via the fire door in the hallway creating a impressive five bedroom, five bathroom, with a queen murphy bed for flex linens, and two private...

  • Charleston
  • 5 Bedrooms
  • 5 Bathrooms
  • Sleeps 12
Large, Historic 6BR, Designed to Perfect...

Summary:Welcome to Palmetto Hideaway, a impressive 6-bedroom designer home in the heart of downtown Charleston. Ideal for huge families, friend getaways, or anyone who craves style, space, and character, it immerses you in history while offering...

  • Charleston
  • 6 Bedrooms
  • 6 Bathrooms
  • Sleeps 16
Brand New Custom Home~ Oceanfront, Pool,...

Step into unparalleled coastal luxury at this freshly constructed, professionally designed oceanfront 5-bedroom home—one of Isle of Palms' premier vacation units. Sandcastle, 2704 Palm Blvd., has every detail crafted for high-end living, from the...

  • Isle of Palms
  • 5 Bedrooms
  • 6 Bathrooms
  • Sleeps 10
Downtown 9BR Mansion with Gym Access + P...

Summary:Recently modernized with two full kitchens and fresh decor, this home comfortably accommodates your entire event. Located in the heart of the city, the Heirloom on Spring extravagant getaway blends historic character with modern comfort...

  • Charleston
  • 9 Bedrooms
  • 6 Bathrooms
  • Sleeps 16
Thomas Waring House | Sleeps 23 | Multi-...

Summary:Welcome to the Thomas Waring House at The Preserve, a historic and award-winning residence that offers a unique blend of appeal and modern convenience. Comprising 4 separate units, this broad property features a total of 11 bedrooms and 11.5...

  • Charleston
  • 11 Bedrooms
  • 11 Bathrooms
  • Sleeps 23
Charming 6bd House w. Pool & Parking, ne...

Summary:Stay in this cavernous 6BR/6BA Charleston getaway, just steps from King Street. Each bedroom offers a king bed and ensuite bath, giving guests both privacy and comfort. With two full kitchens, multiple living areas, and off-street parking...

  • Charleston
  • 6 Bedrooms
  • 6 Bathrooms
  • Sleeps 14
Discounts! Sea Spray- 400 Ocean Blvd. Oc...

Ask about our discounts for Spring/Summer 2026!Tired of looking through tons of listings? Do you need a specific type of home or dates? We are a local family owned company, Exclusive Properties, located right here on Isle of Palms. We specialize in...

  • Isle of Palms
  • 6 Bedrooms
  • 6 Bathrooms
  • Sleeps 15
The Conroy | Perfect Location | Historic...

Permit Number: BL049129-09-2026The Space: Welcome to The Conroy, a remarkable historic building located along iconic Broad Street in the heart of downtown Charleston. Originally constructed around 1794, this attractively preserved property offers a...

  • Charleston
  • 5 Bedrooms
  • 6 Bathrooms
  • Sleeps 15
Guesthouse Charleston: SOUTH (82 A & B)

82 A & B is a roomy two-story home, appealingly located within walking distance of Charleston's best eateries, bars, and attractions. Ideal for enormous groups, the home features two entirely equipped kitchens, two living areas, and multiple outdoor...

  • Charleston
  • 8 Bedrooms
  • 9 Bathrooms
  • Sleeps 18
Brand New Luxury 6 bedrooms, 7.5 bathroo...

Nostos~ 6 51st Ave presented by Exclusive Properties on Isle of Palms. Tired of looking through tons of listings? Do you need a specific type of home or dates? We are a local family owned company, Exclusive Properties, located right here on Isle of...

  • Isle of Palms
  • 6 Bedrooms
  • 7 Bathrooms
  • Sleeps 12
IOP Luxury House With Private Pool, 6 Be...

Only a brief walk from the pristine sandy beach, this gorgeous 6-bedroom, 4.5-bathroom coastal getaway offers the ideal blend of relaxation, style, and convenience. Designed with families and groups in mind, this Isle of Palms vacation home is your...

  • Isle of Palms
  • 6 Bedrooms
  • 4 Bathrooms
  • Sleeps 14