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5+ Bedroom Vacation Rentals

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280 rentals found
Paradise awaits! 7 Bedroom, Private Neig...

Isle of Palms home with pool, beach, stores, and eateries all at your fingertips! This handsome home comfortably sleeps 14, with 7 roomy bedrooms and 5 full bathrooms! Savor a private neighborhood pool. The Pavilion Place neighborhood pool is...

  • Isle of Palms
  • 7 Bedrooms
  • 5 Bathrooms
  • Sleeps 14
Expansive Oceanfront Palm Blvd. 5Bd w/ P...

For those looking to experience a true oceanfront beach vacation on the Isle of Palms, this handsome 5 bedroom home located along beautiful Palm Boulevard is the ideal spot for your next beachfront island hideaway! This home offers gorgeous ocean...

  • Isle of Palms
  • 5 Bedrooms
  • 4 Bathrooms
  • Sleeps 12
The Inns | Luxury Design w. Speakeasy Ba...

Summary:Surrounded by swaying Spanish moss in one of Charleston’s most beautiful neighborhoods, this striking 7-bedroom, 5-bath home captures the essence of Southern grace with a modern twist. Thoughtfully modernized in September 2025, every...

  • Charleston
  • 7 Bedrooms
  • 5 Bathrooms
  • Sleeps 14
STEPS to King St - 6 Bedroom Home - Spac...

Summary:Welcome to your Charleston escape, a generously sized 6-bedroom home constructed for big groups who want to be in the heart of the action yet savor broad living spaces. Ideal for family get-togethers or friend get-togethers, this home offers...

  • Charleston
  • 6 Bedrooms
  • 6 Bathrooms
  • Sleeps 16
The OakTree | Stylish Bohemian Downtown ...

Summary:Welcome to The OakTree, your boho-chic haven in the heart of downtown Charleston, where artistic flair meets generous space. Ideal for sizable groups, families, or creative retreats, this 7-bedroom home offers character, comfort, and close...

  • Charleston
  • 7 Bedrooms
  • 7 Bathrooms
  • Sleeps 16
New design & construction, 6 Bed, 6 EnSu...

Welcome to 183 Saint Philip Street, your chic haven in the heart of Charleston! This new construction offers a prime location, placing you steps away from the city's vibrant attractions & best eateries. Each bedroom features 55" Samsung TVs ...

  • Charleston
  • 6 Bedrooms
  • 6 Bathrooms
  • Sleeps 16
Pavilion a la Plage on Isle of Palms ~ P...

** During the summer we book Saturday to Saturday. Off-season we require a 3 nighttime minimum **--Description--As part of our Island Collection, 'Pavilion a la Plage' 4 10th Ave, is a seven bedroom, five and a half bathroom home located in the...

  • Isle of Palms
  • 7 Bedrooms
  • 5 Bathrooms
  • Sleeps 16
The Palmetto | Rooftop Retreat, Elevated...

Summary:Feel Charleston at its best in this refreshed 5BR/5.5BA getaway, ideal for friends or families. Located in the appealing Cannonborough neighborhood, you’re steps from dining, history, and local appeal. Just 3 blocks from King Street, 20...

  • Charleston
  • 5 Bedrooms
  • 5 Bathrooms
  • Sleeps 12
Spacious Isle of Palms Beach House, Step...

41st Ave 32- Coastal Grace Isle of Palms, South Carolina Overview: Welcome to Coastal Grace! This handsome five bedroom, three bath, pet friendly home is located three blocks from the beach on Isle of Palms. Professionally designed with a fresh...

  • Isle of Palms
  • 5 Bedrooms
  • 3 Bathrooms
  • Sleeps 10
Large Vacation Home in heart of Charlest...

Jan or Feb Specials Available- Work from Charleston with Friends for $10,000 for the whole month!. Send inquiry for details.Welcome to The Penny Palace: Where History Meets Modern Comfort!This 3-story historic gem, is located in the heart of the...

  • Charleston
  • 5 Bedrooms
  • 5 Bathrooms
  • Sleeps 14
Bee & Blossom | Historic Charm

Permit Number: 06191The Space: This former historic Bed and Breakfast has undergone a magical transformation into what is a freshly-modernized 6 bedroom/6.5 bath designer's showcase home in the trendy, laid-back Radcliffborough neighborhood. Close...

  • Charleston
  • 6 Bedrooms
  • 6 Bathrooms
  • Sleeps 12
Lux. IOP Beach 7 Bed Home, Christmas Wee...

Imagine watching the big game from your pool or hot tub... Your luxury vacation awaits at this remarkable Isle of Palms beach estate. Composed of seven bedrooms, seven bathrooms, countless outdoor space, and a impressive backyard getaway with pool...

  • Isle of Palms
  • 7 Bedrooms
  • 7 Bathrooms
  • Sleeps 16
New! Historic Residence – Great For La...

Summary:Welcome to Emerson Square Charleston, a grandiose and professionally designed residence that seamlessly blends Charleston’s rich history with modern luxury. Spanning the entire second and third floors of a meticulously restored historic...

  • Charleston
  • 5 Bedrooms
  • 4 Bathrooms
  • Sleeps 14
Palmetto Hideaway | Historic & Designer ...

Summary:Welcome to Palmetto Hideaway, a impressive 7-bedroom designer home in the heart of downtown Charleston. Ideal for sizable families, friend getaways, or anyone who craves style, space, and character, it immerses you in history while offering...

  • Charleston
  • 7 Bedrooms
  • 6 Bathrooms
  • Sleeps 16
Charming Downtown 6BR - Steps to King St...

Summary:Stay in this cavernous 6BR/6BA Charleston getaway, just steps from King Street. Each bedroom offers a king bed and ensuite bath, giving guests both privacy and comfort. With two full kitchens, multiple living areas, and off-street parking...

  • Charleston
  • 6 Bedrooms
  • 6 Bathrooms
  • Sleeps 14
Stunning Wild Dunes Home-- Fire Pit, Hot...

Welcome to 10 Yacht Harbor, your dream hideaway in Wild Dunes Resort on the pretty Isle of Palms. This newly constructed 5-bedroom vacation rental combines extravagant comfort with the casual appeal of southern coastal living. Just a short 25-min...

  • Isle of Palms
  • 5 Bedrooms
  • 4 Bathrooms
  • Sleeps 12
Downtown Duplex - Spring St - Sleeps 26

Feel the timeless appeal of Charleston’s historic peninsula, the Holy City. Stay just mins. from MUSC, the College of Charleston, and the vibrant shopping, dining, and nightlife of King Street. From this ideally located downtown home, you’ll be...

  • Charleston
  • 8 Bedrooms
  • 8 Bathrooms
  • Sleeps 26
????'Dolphin Manor' ~ OCEAN FRONT, PRIVA...

** During the summer and holidays we book Saturday to Saturday. Off-season we require a 3 nighttime minimum **Description'Dolphin Manor' -512 Ocean Blvd, was completely modernized Spring 2021 and is the ideal oceanfront home for your hideaway! With...

  • Isle of Palms
  • 6 Bedrooms
  • 6 Bathrooms
  • Sleeps 12