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4+ Bedroom Vacation Rentals

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564 rentals found
IOP 6BD Only 3 Min Walk to Beach w/ Priv...

Welcome to #19 on 21st Avenue on the Isle of Palms! Constructed in 2019, this exceptional 6 bedroom Isle of Palms home is a 3400 square foot gem! With two huge living areas and roomy bedrooms that comfortable sleeps 12 guests, it's ideal for...

  • Isle of Palms
  • 6 Bedrooms
  • 5 Bathrooms
  • Sleeps 12
Grand 10 BR Charleston Home with Speakea...

Summary:Draped in Spanish moss and located within a striking Charleston neighborhood, this freshly remodeled huge 10-bedroom, 7-bath getaway blends timeless Southern character with modern luxury. Recently modernized in September 2025, this historic...

  • Charleston
  • 10 Bedrooms
  • 7 Bathrooms
  • Sleeps 26
Guesthouse Charleston: SOUTH (105 B)

Freshly Renovated in 2024! Located on the second floor of a impressive two-unit duplex, this four bedroom, four and a half bathroom home is located on the coveted Spring Street, just steps away from Cannon Green. Feel comfort and style as you step...

  • Charleston
  • 4 Bedrooms
  • 4 Bathrooms
  • Sleeps 10
Screened Porch + Grill: Spacious Charles...

3,000 Sq Ft | Family-Friendly Conveniences | 3 Mi to Folly BeachMake this 5-bedroom, 3-bathroom vacation rental your home base as you discover all Charleston has to offer. The 'James Island Folly Family Retreat' includes multiple living areas, ideal...

  • Charleston
  • 5 Bedrooms
  • 3 Bathrooms
  • Sleeps 10
Downtown Family-Friendly Home By Restaur...

Summary:Flora House occupies the top floor of a majestic Historic Charleston residence dating back to 1905. While thoughtfully modernized for modern living, it delightfully preserves the appeal of its origins, featuring original wood floors and...

  • Charleston
  • 4 Bedrooms
  • 2 Bathrooms
  • Sleeps 8
Private Pool & Historic Home ‘Summer H...

Summary:A short walk to famed King Street, 'The Summer Haze' is a private Charleston home, with private pool! Renovated with modern amenities, experience the appeal of a traditional Charleston home, with comfortable bedrooms & en suite bathrooms...

  • Charleston
  • 4 Bedrooms
  • 4 Bathrooms
  • Sleeps 11
Stunning 6-Bedroom Home with Pool, 5.5 B...

More photos coming soon!Dive in to this freshly remodeled 6-bedroom, 5.5 bathroom home with a brand new pool, ideal for hosting up to 12 guests. This three-story haven, adorned with wood floor, original fireplaces, and high ceilings with exposed...

  • Charleston
  • 6 Bedrooms
  • 5 Bathrooms
  • Sleeps 12
Ultra-Luxury Oceanfront Home | 58 Grand ...

NEW PHOTOS COMING SOON!!Introducing 58 Grandiose Pavilion, your unparalleled luxury escape in the heart of Wild Dunes. This handsome oceanfront getaway, completely refreshed in 2023, offers 6 bedrooms and 6.5 bathrooms across 3,900 square feet of...

  • Isle of Palms
  • 6 Bedrooms
  • 6 Bathrooms
  • Sleeps 12
Downtown Charleston Luxe 9BR/9BA + Parki...

Summary:Substantial groups looking for a authentic, welcoming home away from home in downtown Charleston look no further! Our freshly-refreshed historic home offers three separate 3 bedroom/3 bath units housed within the same home for a total of 9...

  • Charleston
  • 9 Bedrooms
  • 9 Bathrooms
  • Sleeps 18
The OakTree | Stylish Bohemian Downtown ...

Summary:Welcome to The OakTree, your boho-chic haven in the heart of downtown Charleston, where artistic flair meets generous space. Ideal for enormous groups, families, or creative retreats, this 7-bedroom home offers character, comfort, and close...

  • Charleston
  • 7 Bedrooms
  • 7 Bathrooms
  • Sleeps 16
Beautiful Ocean Views w/ Pool and Elevat...

2301 Palm BoulevardProperty Highlights- Grand Private Pool - Can Be Heated - Across the Street from Beach Access Path- Rooftop Deck with Ocean Vistas- Elevator- $250 Beach Gear Credit with 3-14 nighttime stays!Please note that every reservation will...

  • Isle of Palms
  • 6 Bedrooms
  • 5 Bathrooms
  • Sleeps 14
712 Ocean Blvd | New Build + Pool, Game ...

Sun, sand, and wellness collide at Stay Salty—a brand-new, oceanfront getaway on Isle of Palms where modern luxury meets intentional, healthy living. With six bedrooms (including 5 California King beds), six full bathrooms, and a powder room, this...

  • Isle of Palms
  • 6 Bedrooms
  • 7 Bathrooms
  • Sleeps 12
4 Blocks to King! | The Dream Weaver

Permit Number: 06052The Space: Two full apartments. Six bedrooms. Four baths. One seamless stay.This completely refreshed three-story Charleston home is ideal for enormous groups who want space to spread out without sacrificing style. Bright...

  • Charleston
  • 6 Bedrooms
  • 4 Bathrooms
  • Sleeps 14
South 105.5 - Newly Renovated! One Story...

A freshly remodeled downtown bungalow just off Spring Street, designed for guests who want to stay in the heart of Charleston while appreciating a peaceful, private place to relax.Located in the Cannonborough–Elliotborough neighborhood, you're...

  • Charleston
  • 4 Bedrooms
  • 4 Bathrooms
  • Sleeps 8
The Helène Parlor - Spacious 4BD, 4BA -...

Summary:Recently refreshed 4BR/4.5BA home in laid-back Cannonborough/Elliotborough, ideal for families or groups. Just 1 block to Upper King St, 1.5 miles to Market St, 15 min to CHS airport, and 20 min to beaches. Lady Helene Unit C offers...

  • Charleston
  • 4 Bedrooms
  • 4 Bathrooms
  • Sleeps 8
The Pineapple Place | EastBay Historic D...

Summary:Welcome to your Charleston sanctuary where historic appeal meets cavernous luxury. This 5-bedroom getaway offers a generous 3,000 square feet of attractively appointed space. Ideal for families or groups who want fashonable design, room to...

  • Charleston
  • 5 Bedrooms
  • 4 Bathrooms
  • Sleeps 16
Morris Place | Best of Charleston Renova...

Summary:Welcome to Morris Place, a delightfully modernized Charleston home celebrated with the Finest of Charleston award for its blend of architectural character and modern comfort. Ideal for guests who adore design, heritage, and intimate outdoor...

  • Charleston
  • 6 Bedrooms
  • 6 Bathrooms
  • Sleeps 16
Chic 4bd Downtown Home w. Rooftop

Summary:Feel Charleston in style at this chic 4BR/4BA downtown home known as The Charlee. Ideal for groups, it features modern design, a chic kitchen, king beds, and a private rooftop terrace. Savor luxury amenities, an EV charger, and a prime...

  • Charleston
  • 4 Bedrooms
  • 4 Bathrooms
  • Sleeps 15