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Charleston, SC 4+ Bedroom Vacation Rentals

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356 rentals found
Downtown Family-Friendly Home By Restaur...

Summary:Flora House occupies the top floor of a majestic Historic Charleston residence dating back to 1905. While thoughtfully modernized for modern living, it charmingly preserves the appeal of its origins, featuring original wood floors and...

  • Charleston
  • 4 Bedrooms
  • 2 Bathrooms
  • Sleeps 8
Private Historic Residence | 5BR/3BA | S...

Summary:The Quartiers Charlestonian are a blend of historic appeal and modern luxury featuring five queen bedrooms and three baths, two private kitchens and laundry units in which were thoughtfully refreshed. These adjoining historic suites provide...

  • Charleston
  • 5 Bedrooms
  • 3 Bathrooms
  • Sleeps 10
B2 at Saint Philip Square, One Block to ...

Welcome to Saint Philip Square, an award-winning collection of historic homes spanning nearly one city block of downtown Charleston. The Adams Bennett House at 174 B St. Philip St. Unit 2 is a 4 -BD 5- BA second floor gem blends modern comfort with...

  • Charleston
  • 4 Bedrooms
  • 5 Bathrooms
  • Sleeps 14
Luxe Retreat | Near DT & Beaches | 4 BR,...

Summary:Welcome to Southern Shore! Unwind in this bright and modern NEW CONSTRUCTION home on James Island ideal for up to 10 guests. Savor an open layout, cavernous kitchen, 4 comfortable bedrooms, and complimentary beach gear. Unwind in the sizable...

  • Charleston
  • 4 Bedrooms
  • 2 Bathrooms
  • Sleeps 10
Spacious, Historic Home with Porches

Summary:This striking 4bd, 3ba historic home features modern upgrades, brand new furnishings, and a cavernous, comfortable living space for your next trip to Charleston. This property includes the full home with a living room space both floors, full...

  • Charleston
  • 4 Bedrooms
  • 3 Bathrooms
  • Sleeps 12
Cozy 5BR/5BA Downtown House w. Pool & Pa...

Summary:Feel Charleston appeal in this freshly refreshed 5BR/5BA getaway just one block from King Street. Comfortably sleeps 11 with luxe king beds, modern open living spaces, and a completely equipped kitchen. Savor Intelligent TVs, high-speed...

  • Charleston
  • 5 Bedrooms
  • 5 Bathrooms
  • Sleeps 12
Historic Duplex 6 Blocks To King - Lots ...

Summary:Take it simple on the porch after a long day at the beach, then pull up a chair for a casual dinner. This handsome duplex offers a touch of sophistication tucked into historic downtown Charleston.Think of everything you'd want for your ideal...

  • Charleston
  • 6 Bedrooms
  • 4 Bathrooms
  • Sleeps 12
4 Bedroom - 2 Blocks to King Street with...

Feel the timeless appeal of Charleston’s historic peninsula, the Holy City. Stay just mins. from MUSC, the College of Charleston, and the vibrant shopping, dining, and nightlife of King Street. From this ideally located downtown home, you’ll be...

  • Charleston
  • 4 Bedrooms
  • 3 Bathrooms
  • Sleeps 8
Hot Tub • Rooftop • Parking • Walk...

Summary:Welcome to Camellias on Cannon!☀️ Private Rooftop + Courtyard & Hot Tub???? 3 Blocks to King St – Walk to Charleston’s Finest Dining, Shopping & Nightlife???? Ideal for Extensive Groups – Families, Weddings, & Work Retreats???...

  • Charleston
  • 8 Bedrooms
  • 7 Bathrooms
  • Sleeps 16
St. Michael's Place Retreat

St Michael's Place is a short term stay for patients and their families who need to come to Charleston to seek medical treatment. Located in the heart of old James Island, within walking distance to shopping, eateries, nightlife, yoga, farmers...

  • Charleston
  • 4 Bedrooms
  • 1 Bathrooms
  • Sleeps 3
The Trio at 493 - 3 Suites - On King!

Permit Number: 004141The Space: Welcome to 493 Luxury Suites! These charmingly appointed units are found on the second floor of a historic building on King Street (above Sewing Down South, as seen on “Southern Charm”).Step into the building...

  • Charleston
  • 6 Bedrooms
  • 6 Bathrooms
  • Sleeps 18
Classic Home - 5 Star Location - Histori...

Summary:Feel Charleston appeal in this 4BR, 3BA home in the heart of the Historic District. With a Walk Score of 98, you’re just blocks from the iconic City Market and steps to King Street’s top stores, eateries, and rooftops.The Space:This...

  • Charleston
  • 4 Bedrooms
  • 3 Bathrooms
  • Sleeps 8
Charming 4-bedroom house with AC and WiF...

Stay comfortably in Charleston at this 4-bedroom home. Each bedroom features 1 king bed and 3 queen beds, ideal for a group hideaway. Appreciate the serene and calming ambiance of this cozy property, complete with 3 bathrooms equipped with showers...

  • Charleston
  • 4 Bedrooms
  • 2 Bathrooms
  • Sleeps 8
4 Bedroom - 2 Blocks to King Street!

Feel the timeless appeal of Charleston’s historic peninsula, the Holy City. Stay just mins. from MUSC, the College of Charleston, and the vibrant shopping, dining, and nightlife of King Street. From this ideally located downtown home, you’ll be...

  • Charleston
  • 4 Bedrooms
  • 2 Bathrooms
  • Sleeps 12
Luxury Retreat with 4 King Suites

Summary:Discover The Carolina Rose, a brand-new 4-bed, 4-bath luxury Charleston getaway constructed in 2023. Ideal for families or groups, this chic home comfortably sleeps 8+ and is just a 5-block walk from vibrant King Street. Savor modern design...

  • Charleston
  • 4 Bedrooms
  • 4 Bathrooms
  • Sleeps 9
Lowcountry Charm | 4BR Spring St. Home w...

Welcome to the Holy City, and the historic southern appeal of the Charleston peninsula. Our Vacation Rental By Owner is located in gorgeous downtown Charleston and just mins. away from MUSC, the College of Charleston, and King Street’s shopping...

  • Charleston
  • 4 Bedrooms
  • 3 Bathrooms
  • Sleeps 11
Waterfront Private Retreat near Folly Be...

WELCOME TO MARSH MADNESSEscape to your own private corner of the Lowcountry at Marsh Madness, a roomy waterfront getaway surrounded by sweeping marsh and river vistas. With a private pool, deepwater dock, wraparound porches and memorable sunsets...

  • Charleston
  • 5 Bedrooms
  • 4 Bathrooms
  • Sleeps 10
The Mary Scott and Daniel Legare House

Permit Number: 06948The Space: Welcome to your Charleston getaway at 11 George Street!This beautiful and roomy home features 5 elegantly appointed bedrooms and 3 full bathrooms, making it an ideal getaway for families, friends, or bigger groups...

  • Charleston
  • 5 Bedrooms
  • 3 Bathrooms
  • Sleeps 14