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Charleston, SC 4+ Bedroom Vacation Rentals

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357 rentals found
The Monroe | 5BR - Voted Best of Charles...

Summary:Stay at The Monroe on Spring, a entirely modernized 1885 Charleston manor voted Finest of Charleston. Blending historic grandeur with modern luxury, this 5-bedroom getaway features handsome interiors and sprawling porches ideal for calming...

  • Charleston
  • 5 Bedrooms
  • 5 Bathrooms
  • Sleeps 16
Guesthouse Charleston: WEST (64)

Feel elevated Lowcountry living at West 64, a elegantly redesigned 4-bedroom, 4.5-bath Downtown Charleston getaway, tucked within a private courtyard just two blocks from iconic King Street.Ideal for families, friend getaways, wedding guests, and...

  • Charleston
  • 4 Bedrooms
  • 4 Bathrooms
  • Sleeps 10
Charleston Duplex Home 5BR - Walk to Kin...

Welcome to the Holy City, and the historic southern appeal of the Charleston peninsula. Our Vacation Rental By Owner is located in impressive downtown Charleston and just mins. away from MUSC, the College of Charleston, and King Street’s shopping...

  • Charleston
  • 5 Bedrooms
  • 3 Bathrooms
  • Sleeps 10
B2 at Saint Philip Square, One Block to ...

Welcome to Saint Philip Square, an award-winning collection of historic homes spanning nearly one city block of downtown Charleston. The Adams Bennett House at 174 B St. Philip St. Unit 2 is a 4 -BD 5- BA second floor gem blends modern comfort with...

  • Charleston
  • 4 Bedrooms
  • 5 Bathrooms
  • Sleeps 14
5BR Group House | Fire Pit, Movie Deck &...

Bold, bright, and constructed for your whole crew! The entire property is yours, both private units, every bedroom, no one else on site. This Charleston group home sleeps 13 across 5 bedrooms and 3 baths. Packed with arcade games, a fire pit for...

  • Charleston
  • 5 Bedrooms
  • 3 Bathrooms
  • Sleeps 13
Thomas Waring House | Sleeps 23 | Multi-...

Summary:Welcome to the Thomas Waring House at The Preserve, a historic and award-winning residence that offers a unique blend of appeal and modern convenience. Comprising 4 separate units, this broad property features a total of 11 bedrooms and 11.5...

  • Charleston
  • 11 Bedrooms
  • 11 Bathrooms
  • Sleeps 23
Charleston Luxury | Local Design 4BR w/ ...

Summary:Welcome to this handsomely curated 4 bedroom getaway where local design touches meet modern comfort. Ideal for families, modest groups or creative travelers who want style, ease and a spot close to the best of Charleston. You get the tension...

  • Charleston
  • 4 Bedrooms
  • 3 Bathrooms
  • Sleeps 10
The Preserve | Rosemary House Unit C | 5...

Summary:Welcome to the Rosemary House-Suite C at The Preserve, a roomy and elegantly appointed residence occupying the upper floors of a delightfully preserved historic home. With 5 bedrooms and 5 bathrooms, this property offers ample privacy and...

  • Charleston
  • 5 Bedrooms
  • 5 Bathrooms
  • Sleeps 10
Charleston Charm - Downtown - 4 Bedroom

Summary:Welcome to Charleston Charm, your home away from home located in the historic Westside neighborhood. Ideal for families or groups, this newly modernized 4-bedroom home offers space, comfort, and an ideal location just north of downtown...

  • Charleston
  • 4 Bedrooms
  • 2 Bathrooms
  • Sleeps 9
The Overlook on King

Summary:Located on King Street, Charleston’s most impressive and charming retail, entertainment, and dining corridor, The Overlook on King is one of Charleston’s newest and most opulent properties. The highlight is a one-of-a-kind rooftop...

  • Charleston
  • 5 Bedrooms
  • 4 Bathrooms
  • Sleeps 11
Charleston Villa | 6bd, Designer Downtow...

Summary:Welcome to your Charleston escape where cavernous living meets classy design. This six bedroom home is ideal for sizable groups or families looking for comfort, modern amenities, and an inviting patio for gathering. You will savor privacy...

  • Charleston
  • 6 Bedrooms
  • 3 Bathrooms
  • Sleeps 16
Downtown Charleston Home + Private Pool

Summary:Ideal for a sizable family! This listing is for the entire home. The home sleeps 16 guests total. Your stay just got an upgrade. 118B President Street now features a freshly finished private plunge pool, sun deck with loungers, and outdoor...

  • Charleston
  • 6 Bedrooms
  • 6 Bathrooms
  • Sleeps 16
Great for Groups | Private Patio | The Z...

Permit Number: 06281The Space: Welcome to Zeus — a newly redesigned second-floor getaway constructed for comfortable group stays. With 5 bedrooms and 4.5 bathrooms across two upper levels, this cavernous home gives families and bigger groups room...

  • Charleston
  • 5 Bedrooms
  • 4 Bathrooms
  • Sleeps 12
Cozy 5BR/5BA Downtown Gem - Close to Kin...

Summary:Feel Charleston appeal in this freshly remodeled 5BR/5BA getaway just one block from King Street. Comfortably sleeps 11 with luxe king beds, modern open living spaces, and a completely equipped kitchen. Savor Intelligent TVs, high-speed...

  • Charleston
  • 5 Bedrooms
  • 5 Bathrooms
  • Sleeps 12
Stylish 5BR/5BA Downtown Retreat - Walk ...

Summary:Stay in this freshly remodeled 5-bedroom, 5-bathroom downtown getaway accommodating up to 12 guests. Featuring open concept living areas, a entirely equipped kitchen, extravagant king beds, and off-street parking. Just one block from King...

  • Charleston
  • 5 Bedrooms
  • 5 Bathrooms
  • Sleeps 12
The Edisto River Complex- 4 Condo Comple...

The PERFECT vacation rental for Weddings, Giant Groups and Families looking to travel in complete extravagant comfort and privacy! This 4 Condo- 8 Bedroom/ 8 Bathroom Complex is the ONLY property in Charleston that can host your entire event in...

  • Charleston
  • 8 Bedrooms
  • 8 Bathrooms
  • Sleeps 24
Spacious James Island 4br/3.5ba House wi...

Welcome to this 4br/3.5ba home located on James Island, only a 10 min drive to Downtown Charleston or a 15 min drive to Folly Beach! Home has 2500sqft of living space on two floors with two living areas so there is plenty of room for everybody to...

  • Charleston
  • 4 Bedrooms
  • 3 Bathrooms
  • Sleeps 12
Beautiful King Street 4 Bedroom! 30 Day ...

Summary:Welcome to this freshly refreshed 4-bedroom rental in the heart of downtown Charleston, designed for both relaxation and productivity. Each bedroom features a king-size bed and intelligent TV. For those blending travel with work, two...

  • Charleston
  • 4 Bedrooms
  • 2 Bathrooms
  • Sleeps 8