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Charleston, SC 4+ Bedroom Vacation Rentals

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359 rentals found
Historic Charleston home located in the ...

Located in the heart of downtown Charleston, John Street offers the ideal blend of accessibility and tranquility. Within walking distance to all the top attractions in downtown, this home is tucked away in the peaceful Garden District, bordered by...

  • Charleston
  • 4 Bedrooms
  • 5 Bathrooms
  • Sleeps 8
Marsh-View Retreat | 8 Guests, 10 Mins t...

Summary:Welcome to Lowcountry Lookout!Feel true Charleston appeal in the ❤️ of West Ashley in this newly refreshed Marsh Front getaway. Ideal for families or groups who want comfort and privacy. You will adore how relaxing and safe the...

  • Charleston
  • 4 Bedrooms
  • 2 Bathrooms
  • Sleeps 8
Southern Elegance Meets Charleston Charm...

Summary:Welcome to your serene Charleston getaway, where traditional Southern appeal meets the vibrant lifestyle of one of America's most celebrated cities. Located in a beautiful neighborhood adorned with age-old oak trees and sunlit avenues, our...

  • Charleston
  • 4 Bedrooms
  • 1 Bathrooms
  • Sleeps 8
Fun Family-Friendly Home near Folly with...

Come stay at our Funky, Fun, Folly-Adjacent Home! Our sizable, oak-filled property is located in a peaceful, family-friendly residential neighborhood just 2 miles off the beach. Cut your travel time in half whether you are spending your days at...

  • Charleston
  • 4 Bedrooms
  • 2 Bathrooms
  • Sleeps 6
Island Retreat - Great for Large Groups

Summary:Conveniently located on James Island, 5 miles from Folly Beach and Downtown Charleston, this lush live oak property features 3 separate units that share a cavernous backyard. The individual units provide plenty of space for privacy with 1...

  • Charleston
  • 5 Bedrooms
  • 3 Bathrooms
  • Sleeps 14
The Bogard Duo 6 Bed 6 Bath

Recently-remodeled six bedroom historic home in the trendy, laid-back Cannonborough neighborhood close to great eateries & historical sights.This classic Charleston home is made up of two units A&B, this is the listing for both units. The entire...

  • Charleston
  • 6 Bedrooms
  • 6 Bathrooms
  • Sleeps 12
The Helène House - Spacious 4BD, 4.5BA ...

Summary:Freshly remodeled 4BR/4.5BA home in laid-back Cannonborough/Elliotborough, ideal for families or friends. Lady Helene, Unit B features 4 ensuite bedrooms, open living/dining, a entirely equipped kitchen, games room, private porch...

  • Charleston
  • 4 Bedrooms
  • 4 Bathrooms
  • Sleeps 8
The Chapel | Manor 4BR Charming Charlest...

Summary:Welcome to your Charleston getaway located just moments from King Street, where classic appeal meets modern comfort. This 4-bedroom, 4-bath home is ideal for families or groups who want privacy, ease, and access to Charleston’s best...

  • Charleston
  • 4 Bedrooms
  • 4 Bathrooms
  • Sleeps 10
Rooftop Patio | Private Pool | The Athen...

Permit Number: 06283The Space: Welcome to Athena — a cavernous 3-story downtown getaway constructed for gathering. With 5 bedrooms, 3.5 baths, and a bright open layout, this home is ideal for families and bigger groups who want room to spread out...

  • Charleston
  • 5 Bedrooms
  • 3 Bathrooms
  • Sleeps 10
4 Bedrooms - 4 Blocks to King Street wit...

Feel the timeless appeal of Charleston’s historic peninsula, the Holy City. Stay just mins. from MUSC, the College of Charleston, and the vibrant shopping, dining, and nightlife of King Street. From this ideally located downtown home, you’ll be...

  • Charleston
  • 4 Bedrooms
  • 2 Bathrooms
  • Sleeps 10
The Lord Ashley - Sleeps 8!

Our sun-filled home features an inviting open floor plan that includes two sitting rooms and a enormous dining area with bar that leads into the roomy chef's kitchen. The entirely equipped kitchen is complete with stainless steel appliances...

  • Charleston
  • 4 Bedrooms
  • 2 Bathrooms
  • Sleeps 8
Perfect family home in West Ashley, minu...

PROMO 5% WEEKLY DISCOUNT!Welcome to your home away from home while in Charleston. Our 2000 square foot home is located in a peaceful neighborhood, encompassed in the beauty of Low Country Marshes in West Ashley. We have lovingly modernized the home...

  • Charleston
  • 4 Bedrooms
  • 2 Bathrooms
  • Sleeps 8
Cozy 5BR/5BA Downtown Gem - Close to Kin...

Summary:Feel Charleston appeal in this freshly modernized 5BR/5BA getaway just one block from King Street. Comfortably sleeps 11 with luxe king beds, modern open living spaces, and a completely equipped kitchen. Appreciate Intelligent TVs...

  • Charleston
  • 5 Bedrooms
  • 5 Bathrooms
  • Sleeps 12
Chateau Charleston | Luxury Oasis w/ 3 N...

Summary:Welcome to Chateau Charleston, a opulent getaway comprised of three newly constructed homes on a shared property, offering style, privacy, and resort-like amenities. Ideal for multiple families or groups traveling together, this compound...

  • Charleston
  • 4 Bedrooms
  • 4 Bathrooms
  • Sleeps 16
Historic Meets Modern on King Street– ...

King St. Commons – Upscale Downtown Living in the Heart of CharlestonWelcome to King St. Commons – A beautiful Duo of King's Court and Park's Edge! Steps from King Street's best eateries, stores, and nightlife, King St. Commons is a beautiful...

  • Charleston
  • 4 Bedrooms
  • 3 Bathrooms
  • Sleeps 12
The Chapel | Verdana 4BR DT Charleston -...

Summary:Welcome to The Chapel, your downtown Charleston getaway combining historic appeal, modern amenities, and unbeatable walkability. Ideal for families, groups of friends, or modest gatherings, this 4-bedroom home offers style, comfort, and a...

  • Charleston
  • 4 Bedrooms
  • 4 Bathrooms
  • Sleeps 10
The Chapel | Premier 13BR Estate in Down...

Located in the city center, this welcoming vacation home brings all of Charleston within your reach. Upper King Design District is an simple 11-min. walk away, so you can leave your car at the property, which offers onsite parking, or jump in your...

  • Charleston
  • 13 Bedrooms
  • 12 Bathrooms
  • Sleeps 16
The Inns - Beautiful 6BR / 6BA - Walk to...

Summary:Welcome to this refined 6-bedroom, 6-bathroom home from The Inns collection. Professionally designed and newly modernized, it offers fresh comfort mins. from King Street’s vibrant energy, ideal for enormous groups seeking luxury and...

  • Charleston
  • 6 Bedrooms
  • 6 Bathrooms
  • Sleeps 16