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Charleston, SC 4+ Bedroom Vacation Rentals

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358 rentals found
Casa Zoë | Royal House – Charleston...

Summary:OP2025-06816OP2025-06817The Royal House is Charleston’s ultimate group escape: a dual-unit Casa Zoë mansion that blends grandeur, design, and independence. With 8 bedrooms, 8 baths, and separate living quarters, it offers shared elegance...

  • Charleston
  • 8 Bedrooms
  • 10 Bathrooms
  • Sleeps 16
Game Room• Fireplace • Backyard Deck...

Welcome to Your Storybook Hideaway * 16 miles to Historic Downtown Charleston* 25 miles to Folly Beach and Isle of Palm* 6.4 miles to Charleston International Airport* Free Wi-Fi and self-check-in* Free parking available* Fireplace* Entirely...

  • Charleston
  • 4 Bedrooms
  • 2 Bathrooms
  • Sleeps 10
Thomas Waring House | Unit A | Sleeps 11

Summary:Welcome to Thomas Waring House-Suite A at The Preserve, a historic and award-winning residence that offers a unique blend of appeal and modern convenience. This luxury suite in downtown Charleston is comprised of 5 bedrooms and 5.5...

  • Charleston
  • 5 Bedrooms
  • 5 Bathrooms
  • Sleeps 11
Private Pool & Historic Home - ‘Sugars...

Summary:Adjacent to an iconic Charleston bakery, 'The Sugarsweet House' is a 5 min. walk to famed King Street. This remodeled historic home includes a private pool. Appreciate the modern kitchen, striking living & dining area, the serene pool deck...

  • Charleston
  • 4 Bedrooms
  • 4 Bathrooms
  • Sleeps 8
Rooftop • Hot Tub • Parking • 3 Bl...

Summary:✨ Welcome to Camellias on Cannon – Suite B! ????☀️ Private Rooftop Deck???? Courtyard with Hot Tub???? Ideal for Enormous Groups – Families, Wedding Guests, Bachelor(ettes) & Work Retreats???? 3 Blocks to King St! Walk to...

  • Charleston
  • 4 Bedrooms
  • 3 Bathrooms
  • Sleeps 8
Guesthouse Charleston: SOUTH (105 ALL)

This combined listing for South 105 A, B, & 105.5 is a great space for enormous groups. Each unit has 4 bedrooms, and 4.5 bathrooms totalling 12 bedrooms, 12 full bathrooms, 3 half bathrooms, 3 full kitchen/living areas. Located on the desired...

  • Charleston
  • 12 Bedrooms
  • 13 Bathrooms
  • Sleeps 28
The Coral Steps to King and Michelin Res...

Summary:Welcome to The Coral, a delightfully designed four-story residence located in the heart of downtown Charleston. This 4-bedroom, 2.5-bathroom home offers the ideal blend of historic Charleston appeal and modern city living.The Space:Welcome...

  • Charleston
  • 4 Bedrooms
  • 2 Bathrooms
  • Sleeps 11
Downtown Charleston Gem | Walk Everywher...

Summary:Welcome to The Lavender???? & Sage Suites ???? a charmingly restored 6BR 6.5BA home that pairs modern luxury with timeless Southern appeal. Located in the heart of downtown Charleston, you're just steps from the city's best eateries...

  • Charleston
  • 6 Bedrooms
  • 6 Bathrooms
  • Sleeps 12
Group Getaway - 6BR/6BA in Heart of Char...

Summary:Feel true Charleston appeal in this remodeled historic home offers three separate 3 bedroom/3 bath units housed within the same home for a total of 9 bedrooms (each with its own FULL en-suite bathroom), 3 full kitchens, outdoor porch space...

  • Charleston
  • 6 Bedrooms
  • 6 Bathrooms
  • Sleeps 12
East 204 - Entire Home 1 Block to King!

East 204 is a alluring standalone two story home located one block to King Street. The home has a impressive main floor boasting an open living, dining, and kitchen area. Just off the main living area, there is one bedroom with an ensuite bathroom...

  • Charleston
  • 4 Bedrooms
  • 3 Bathrooms
  • Sleeps 8
New Build | <10 Mins to Folly & <15 to D...

Summary:Welcome to Salt Air Stay!Unwind in this bright & modern NEW CONSTRUCTION home on James Island that sleeps 10 guests with an open layout, and 4 bedrooms and 5 beds. Savor the enormous backyard and screened in porch and make this your ideal...

  • Charleston
  • 4 Bedrooms
  • 3 Bathrooms
  • Sleeps 10
Ivy Manor | DT Oasis + Carriage House!

Summary:Welcome to your Charleston getaway where artistry meets comfort and privacy. This stay features a main home plus a private carriage home, offering space, style, and a sense of getaway. Ideal for families or groups wanting design-forward...

  • Charleston
  • 8 Bedrooms
  • 4 Bathrooms
  • Sleeps 16
Beautiful 6BR / 6BA w. Parking, Walk to ...

Summary:Welcome to this refined 6-bedroom, 6-bathroom home from The Heirloom collection. Professionally designed and freshly modernized, it offers fresh comfort mins. from King Street’s vibrant energy, ideal for enormous groups seeking luxury and...

  • Charleston
  • 6 Bedrooms
  • 6 Bathrooms
  • Sleeps 16
Stunning 6-Bedroom Home with Pool, 5.5 B...

More photos coming soon!Dive in to this freshly remodeled 6-bedroom, 5.5 bathroom home with a brand new pool, ideal for hosting up to 12 guests. This three-story haven, adorned with wood floor, original fireplaces, and high ceilings with exposed...

  • Charleston
  • 6 Bedrooms
  • 5 Bathrooms
  • Sleeps 12
Luxe, Historic 1840s House

Summary:Feel historic Charleston in our modernized 1840s home, ideal for groups of up to 12. This cavernous getaway features 4 king beds, 2 kitchens, 2 living rooms, and classic porches. Located on a impressive street, you're just a short walk from...

  • Charleston
  • 4 Bedrooms
  • 2 Bathrooms
  • Sleeps 11
Spacious & Modern 4bd, 2 blocks to King!

Summary:Welcome to your appealing Charleston getaway just two blocks from lively King Street. This roomy 4-bedroom, 5-bath home blends comfort and style. Step outside and walk to the city’s best eateries, stores, and nightlife, then return to...

  • Charleston
  • 4 Bedrooms
  • 5 Bathrooms
  • Sleeps 9
4 Bedroom - 2 Blocks to King Street!

Feel the timeless appeal of Charleston’s historic peninsula, the Holy City. Stay just mins. from MUSC, the College of Charleston, and the vibrant shopping, dining, and nightlife of King Street. From this ideally located downtown home, you’ll be...

  • Charleston
  • 4 Bedrooms
  • 2 Bathrooms
  • Sleeps 12
1 Block to King St | Plunge Pool | Sleep...

Summary:Feel luxury at The Pink Palm, a gorgeous new construction 4-bedroom, 4-bathroom getaway in downtown Charleston finished in APR 2025. Appreciate cavernous living areas, fashonable baths, and a completely equipped kitchen. Unwind in the...

  • Charleston
  • 4 Bedrooms
  • 4 Bathrooms
  • Sleeps 10