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Charleston, SC 4+ Bedroom Vacation Rentals

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358 rentals found
*Newly Renovated!* Guesthouse Charleston...

Welcome to your home away from home in the heart of Charleston. This attractively modernized four-bedroom, four-and-a-half-bathroom residence is located on the first floor of a striking two-unit duplex on the highly charming Spring Street just steps...

  • Charleston
  • 4 Bedrooms
  • 4 Bathrooms
  • Sleeps 10
Private Pool & Historic Home - ‘Sugars...

Summary:Adjacent to an iconic Charleston bakery, 'The Sugarsweet House' is a 5 min. walk to famed King Street. This modernized historic home includes a private pool. Savor the modern kitchen, beautiful living & dining area, the serene pool deck, and...

  • Charleston
  • 4 Bedrooms
  • 4 Bathrooms
  • Sleeps 8
Spring Complex - Walk to King St

Savor the convenience of this downtown triplex. This home is located in a marvelous neighborhood just a 6-7 min. walk to King Street, 1-2 min. walk to MUSC campus, and a short ride to the historical district and Rainbow Row. Booking this location as...

  • Charleston
  • 4 Bedrooms
  • 4 Bathrooms
  • Sleeps 12
The Mary Scott and Daniel Legare House

Permit Number: 06948The Space: Welcome to your Charleston getaway at 11 George Street!This striking and cavernous home features 5 handsomely appointed bedrooms and 3 full bathrooms, making it an ideal getaway for families, friends, or bigger groups...

  • Charleston
  • 5 Bedrooms
  • 3 Bathrooms
  • Sleeps 16
Luxury 8BR/6.5BA Downtown w Outdoor Spac...

Summary:Bring everybody together in this roomy 8BR/6.5BA Charleston home featuring two kitchens, dual living areas, and chic design throughout. Just 4 blocks from King Street, this getaway offers modern amenities with historic appeal, high-speed...

  • Charleston
  • 8 Bedrooms
  • 6 Bathrooms
  • Sleeps 18
The Madison- Historic Charleston Single ...

Encompass yourself in the history of Charleston by staying in this newly modernized 1890`s single home. This entire two story home offers guests all the aesthetic features of a Charleston Single House from its enormous double piazzas with blue...

  • Charleston
  • 5 Bedrooms
  • 5 Bathrooms
  • Sleeps 13
Spring St - Downtown Charleston - Walk E...

Feel the timeless appeal of Charleston’s historic peninsula, the Holy City. Stay just mins. from MUSC, the College of Charleston, and the vibrant shopping, dining, and nightlife of King Street. From this ideally located downtown home, you’ll be...

  • Charleston
  • 4 Bedrooms
  • 4 Bathrooms
  • Sleeps 10
The Marquee On King & Historic Market!

Permit Number: 51196The Space: Welcome to The Marquee, a cavernous two-level condo combination located directly on historic King Street and ideal for enormous groups exploring downtown Charleston!With two connected condos spanning the second and...

  • Charleston
  • 6 Bedrooms
  • 4 Bathrooms
  • Sleeps 13
Luxurious Escape in Downtown Charleston ...

Permit Number: 06280The Space: Welcome to Apollo — a roomy first-floor getaway designed for casual downtown living. With 4 bedrooms and 3.5 bathrooms all on one level, this home offers an simple layout for families and groups who want comfort and...

  • Charleston
  • 4 Bedrooms
  • 3 Bathrooms
  • Sleeps 9
Luxury Retreat with 4 King Suites

Summary:Discover The Carolina Rose, a brand-new 4-bed, 4-bath luxury Charleston getaway constructed in 2023. Ideal for families or groups, this classy home comfortably sleeps 8+ and is just a 5-block walk from vibrant King Street. Savor modern...

  • Charleston
  • 4 Bedrooms
  • 4 Bathrooms
  • Sleeps 9
Only 5 blocks to King! | Rose and Petuni...

Permit Number: 06089The Space: Located on Rutledge Avenue in Charleston’s vibrant Cannonborough neighborhood, this newly modernized 4-bedroom, 4-bath property features two private apartments, ideal for groups who want space, comfort, and...

  • Charleston
  • 4 Bedrooms
  • 4 Bathrooms
  • Sleeps 10
Chic Historic Victorian Duplex 2 Blocks ...

Summary:Stay at The Dunes on Spring, our delightfully remodeled 1905 Charleston Victorian duplex home in the heart of Cannonborough. Just 2 blocks from King Street, this striking property features nearly 2600 square feet of ideally designed space...

  • Charleston
  • 6 Bedrooms
  • 3 Bathrooms
  • Sleeps 13
Grand 18bd House w. Luxury Finishes + Pa...

Summary:As part of the esteemed collection, The Heirloom, this impressive 18-bedroom compound is located on Spring Street in the heart of Charleston. Ideal for enormous groups, this completely refreshed property combines two fashonable Victorian...

  • Charleston
  • 18 Bedrooms
  • 14 Bathrooms
  • Sleeps 30
The Manor by Guesthouse Charleston- Gran...

91A Spring Street is a elegantly restored Victorian Home. This home has 4 bedrooms and 4.5 bathrooms a huge open living, dining, and kitchen area that opens up to cavernous front porches that overlook the piazza. Each bedroom has a private ensuite...

  • Charleston
  • 4 Bedrooms
  • 4 Bathrooms
  • Sleeps 10
The Helène Parlor - Spacious 4BD, 4BA -...

Summary:Freshly modernized 4BR/4.5BA home in laid-back Cannonborough/Elliotborough, ideal for families or groups. Just 1 block to Upper King St, 1.5 miles to Market St, 15 min to CHS airport, and 20 min to beaches. Lady Helene Unit C offers...

  • Charleston
  • 4 Bedrooms
  • 4 Bathrooms
  • Sleeps 8
Lowcountry Family Getaway-A Charleston A...

RENOVATED, ROOMY & READY! This roomy 3238 square ft, upgraded home is a exceptional value for your family beach vacation, golf trip, or wedding season get together with friends!! No matter the occasion, this home will surely host you and your group...

  • Charleston
  • 4 Bedrooms
  • 3 Bathrooms
  • Sleeps 18
Guesthouse Charleston: WEST (242 B & C)

West 242 B and 242 C are two impressive standalone homes located in the heart of Charleston's vibrant Cannonborough/Elliotborough neighborhood, just two blocks from historic King Street. This prime location offers simple access to Charleston's best...

  • Charleston
  • 8 Bedrooms
  • 6 Bathrooms
  • Sleeps 16
Hidden Gem • Close to Downtown & Beach...

Summary:Welcome to Lowcountry Lookout ???? A calming marsh front getaway in the heart of West Ashley! Surrounded by handsome oak trees, you’re just mins. from Charleston’s top attractions, eateries, beaches, and historic sites. Unwind by the...

  • Charleston
  • 4 Bedrooms
  • 2 Bathrooms
  • Sleeps 8