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Charleston, SC 4+ Bedroom Vacation Rentals

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362 rentals found
The Historic St. Philip House - One Bloc...

Construction Notice (Updated 6/3/26)Daniel and I would like to inform you of a construction project taking place close to this home.UPDATE:- The townhomes next to us will be finished by the end of June, 2026.- The building behind us is supposed to...

  • Charleston
  • 4 Bedrooms
  • 3 Bathrooms
  • Sleeps 8
Cozy 4bd Home with Porch, Near King Stre...

Summary:Welcome to your cavernous Charleston getaway, where modern remodel meets classic appeal. This rare 4-bedroom home is made up of two entirely equipped units rented together, offering the ideal setup for families or groups who want both...

  • Charleston
  • 4 Bedrooms
  • 2 Bathrooms
  • Sleeps 10
3 Luxury Houses w/ Patios | 1 Block from...

Summary:Discover luxury set of three completely modernized luxury homes ideal for a sizable group, located next door to each other just moments from King St. Indulge in beautiful interiors awash with natural light from wrap-around windows. These...

  • Charleston
  • 12 Bedrooms
  • 10 Bathrooms
  • Sleeps 30
Blue Magnolia | Perfect for Large Groups

Summary:Discover Blue Magnolia, your modren and cavernous Charleston getaway. This 7BR/4BA home combines classic Southern appeal with modern comfort, making it ideal for families or groups. Unwind on the inviting front porch, soak in the airy...

  • Charleston
  • 7 Bedrooms
  • 4 Bathrooms
  • Sleeps 17
Downtown Charleston Luxe 9BR/9BA + Parki...

Summary:Grand groups looking for a authentic, welcoming home away from home in downtown Charleston look no further! Our newly-remodeled historic home offers three separate 3 bedroom/3 bath units housed within the same home for a total of 9 bedrooms...

  • Charleston
  • 9 Bedrooms
  • 9 Bathrooms
  • Sleeps 18
Luxury 8BR/6.5BA Downtown w Outdoor Spac...

Summary:Bring everybody together in this roomy 8BR/6.5BA Charleston home featuring two kitchens, dual living areas, and chic design throughout. Just 4 blocks from King Street, this getaway offers modern amenities with historic appeal, high-speed...

  • Charleston
  • 8 Bedrooms
  • 6 Bathrooms
  • Sleeps 18
B1 at Saint Philip Square, One Block to ...

Welcome to Saint Philip Square, an award-winning collection of historic homes spanning nearly one city block of downtown Charleston. The Adams Bennett House at 174 B#1 Saint Philip Street is a 4-bed 4-bath first floor gem that blends modern comfort...

  • Charleston
  • 4 Bedrooms
  • 4 Bathrooms
  • Sleeps 10
Harleston House | Unit A | Sleeps 8

Summary:Welcome to the Harleston House in the Preserve, a modren 4-bedroom, 4-bathroom luxury suite in downtown Charleston. This modern getaway, complete with modern furnishings and a private plunge pool, offers an exclusive escape for guests...

  • Charleston
  • 4 Bedrooms
  • 4 Bathrooms
  • Sleeps 8
Guesthouse Charleston: WEST (64)

Feel elevated Lowcountry living at West 64, a gorgeously redesigned 4-bedroom, 4.5-bath Downtown Charleston getaway, tucked within a private courtyard just two blocks from iconic King Street.Ideal for families, friend getaways, wedding guests, and...

  • Charleston
  • 4 Bedrooms
  • 4 Bathrooms
  • Sleeps 10
6 Bedrooms! One Block to King Street!

Summary:Welcome to your Charleston gathering home, a six-bedroom property just one block from King Street that offers space, character, and plenty of outdoor appeal. Ideal for enormous families or groups who want walk-ability, historic details, and...

  • Charleston
  • 6 Bedrooms
  • 4 Bathrooms
  • Sleeps 14
4BR New - Close to Folly Beach!

Escape to this charming 2025-constructed home on James Island, just 10 mins. from Folly Beach and 20 mins. from downtown Charleston. Featuring 4 cavernous bedrooms, 3.5 bathrooms, an open-concept layout, entirely equipped kitchen, garage access...

  • Charleston
  • 4 Bedrooms
  • 3 Bathrooms
  • Sleeps 8
Charleston Luxury | Local Design 4BR w/ ...

Summary:Welcome to this attractively curated 4 bedroom getaway where local design touches meet modern comfort. Ideal for families, modest groups or creative travelers who want style, ease and a spot close to the best of Charleston. You get the...

  • Charleston
  • 4 Bedrooms
  • 3 Bathrooms
  • Sleeps 10
Welcome to The Crystal Palace — Perfec...

DOWNTOWN LUXURY — THE CRYSTAL PALACEA restored 1850s Charleston Single glowing with chandeliers in every room, unmatched downtown walkability, amazing parking, and fast access to Charleston’s best beaches and waterfront dining.The Crystal Palace...

  • Charleston
  • 6 Bedrooms
  • 5 Bathrooms
  • Sleeps 12
Boho Rosa | Famous Pink House with Pool ...

Summary:Welcome to Boho Rosa, an award-winning, modernized Charleston-style home where vibrant design meets classic Southern appeal. With its memorable pink exterior and professionally decorated bohemian-chic interior, this home offers a really...

  • Charleston
  • 5 Bedrooms
  • 4 Bathrooms
  • Sleeps 14
Pet Friendly Spacious 4BR Family Home Ne...

Kick back and relax in this calm, modren home just mins. from some of Charleston's most trendy attractions. This home is a ideal central location as you discover all Charleston has to offer. The home is located on a peaceful street with plenty of...

  • Charleston
  • 4 Bedrooms
  • 2 Bathrooms
  • Sleeps 10
East 204 - Entire Home 1 Block to King!

East 204 is a gorgeous standalone two story home located one block to King Street. The home has a handsome main floor boasting an open living, dining, and kitchen area. Just off the main living area, there is one bedroom with an ensuite bathroom...

  • Charleston
  • 4 Bedrooms
  • 3 Bathrooms
  • Sleeps 8
Revitalized Historical Southern Residenc...

Summary:Ideal for a sizable family! Just one block away from upper King Street, the new epicenter of the city's acclaimed restaurant and nightlife district. Appreciate some of Charleston's best local dining, all located within just a few blocks of...

  • Charleston
  • 4 Bedrooms
  • 3 Bathrooms
  • Sleeps 10
Downtown Charleston - 4 Bedrooms / 2 Bat...

Summary:Step into this bright 4 bedroom, 2 bathroom home ideally suited for families or groups who adore space, style, and convenience.The Space:Located in downtown Charleston, this home offers an effortless mix of historic appeal and modern living...

  • Charleston
  • 4 Bedrooms
  • 2 Bathrooms
  • Sleeps 10