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Charleston, SC 4+ Bedroom Vacation Rentals

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356 rentals found
Downtown Historic Home Steps to King St

Summary:Welcome to this impressive Southern bungalow, where classic elegance meets modern comfort. This enchanting home features four roomy bedrooms and two elegantly appointed bathrooms, ideal for family living or entertaining guests. The inviting...

  • Charleston
  • 4 Bedrooms
  • 2 Bathrooms
  • Sleeps 12
Professionally Designed 5bd Retreat, Ste...

Summary:Welcome to Emerson Square, a grandiose professionally designed getaway of a elegantly restored historic building, this broad five-bedroom residence is ideal for families and enormous groups. Appreciate a chef’s kitchen, SMART TVs...

  • Charleston
  • 5 Bedrooms
  • 4 Bathrooms
  • Sleeps 15
‘Pacific Blue’ – Historic Home 5 m...

Summary:'The Pacific Blue' at The Blue Haven is a 5 min. walk to famed King Street. This modernized historic home includes a modern kitchen, appealing living area, and a traditional private piazza to lounge in the shade & watch the city go by.The...

  • Charleston
  • 4 Bedrooms
  • 4 Bathrooms
  • Sleeps 8
Charming 4-bedroom house with AC and WiF...

Stay comfortably in Charleston at this 4-bedroom home. Each bedroom features 1 king bed and 3 queen beds, ideal for a group hideaway. Savor the serene and relaxing ambiance of this cozy property, complete with 3 bathrooms equipped with showers and...

  • Charleston
  • 4 Bedrooms
  • 2 Bathrooms
  • Sleeps 8
Spacious, Large 4bd w/ Outdoor Dining, n...

Summary:Feel the ideal fusion of history and modern luxury at this exceptional 4-bedroom, 3-bath residence. This elegantly modernized home offers an elevated getaway in the heart of the city. Located just three blocks from vibrant King Street...

  • Charleston
  • 4 Bedrooms
  • 3 Bathrooms
  • Sleeps 9
The Grand Helène - Newly Renovated 11BD...

Summary:Recently constructed 11BR/11.5BA home in the laid-back Cannonborough/Elliotborough neighborhood—ideal for sizable groups seeking space and privacy. The property features three separate units in one building, ideal for gathering together...

  • Charleston
  • 11 Bedrooms
  • 12 Bathrooms
  • Sleeps 22
Waterfront Oasis w/Ocean Access Minutes ...

Welcome to a slice of heaven where modern elegance meets unmatched location. This striking home offers 4 roomy bedrooms, 2 bathrooms, and a lifestyle defined by comfort and serenity. Located on a property that backs onto the pretty Parrot Point...

  • Charleston
  • 4 Bedrooms
  • 2 Bathrooms
  • Sleeps 9
Casa Zoë | Royal Cottage I – Designer...

Summary:OP2025-06816Royal Cottage I is a design-rich Casa Zoë getaway, combining classic Charleston appeal with gallery-style interiors and thoughtful details throughout. Featuring four bedrooms and five baths, vaulted ceilings, Slim...

  • Charleston
  • 4 Bedrooms
  • 5 Bathrooms
  • Sleeps 8
Largest Private Pool Downtown | Mint Jul...

Permit Number: 06995The Space: Step into a world of opulence and relaxation at The Mint Julep House, where every detail has been meticulously curated for an extraordinary stay. This two-story residence, newly remodeled and impeccably furnished...

  • Charleston
  • 6 Bedrooms
  • 5 Bathrooms
  • Sleeps 12
Rare French Quarter Escape, Sleeps 16 w....

Summary:Located in the heart of the French Quarter and draped in history, this private, secure 3,300 sq. ft. luxury getaway comfortably sleeps 16 guests with 5 roomy bedrooms, dual master suites, ensuite bathrooms, and upgraded luxury amenities...

  • Charleston
  • 5 Bedrooms
  • 4 Bathrooms
  • Sleeps 16
Downtown Duplex - St Philip St

Feel the timeless appeal of Charleston’s historic peninsula, the Holy City. Stay just mins. from MUSC, the College of Charleston, and the vibrant shopping, dining, and nightlife of King Street. From this ideally located downtown home, you’ll be...

  • Charleston
  • 6 Bedrooms
  • 5 Bathrooms
  • Sleeps 16
The King Suites at 493 - 8 Suites, 16 Be...

Permit Number: 004141The Space: Welcome to 493 Luxury Suites! These charmingly appointed units are found on the second floor of a historic building on King Street (above Sewing Down South, as seen on “Southern Charm”).Step into the building...

  • Charleston
  • 16 Bedrooms
  • 16 Bathrooms
  • Sleeps 52
4 Blocks to King! | The Dream Weaver

Permit Number: 06052The Space: Two full apartments. Six bedrooms. Four baths. One seamless stay.This entirely remodeled three-story Charleston home is ideal for sizable groups who want space to spread out without sacrificing style. Bright interiors...

  • Charleston
  • 6 Bedrooms
  • 4 Bathrooms
  • Sleeps 14
Emerald House | 4BR Charleston Charm Nea...

Summary:Step into a sophisticated getaway where historic touches meet modern design. This 4 bedroom home offers the ideal balance of elegance and comfort, making it an elegant choice for families, groups of friends or business travelers who want...

  • Charleston
  • 4 Bedrooms
  • 3 Bathrooms
  • Sleeps 12
Guesthouse Charleston: WEST (62 & 64)

West 62 and 64 are two impressive homes located next door to each other, sharing a roomy outdoor courtyard ideal for calming with drinks after a day of exploring Charleston. Each home offers generous living spaces, huge bedrooms, and multiple...

  • Charleston
  • 8 Bedrooms
  • 9 Bathrooms
  • Sleeps 20
Downtown Duplex - Rutledge Avenue

Feel the timeless appeal of Charleston’s historic peninsula, the Holy City. Stay just mins. from MUSC, the College of Charleston, and the vibrant shopping, dining, and nightlife of King Street. From this ideally located downtown home, you’ll be...

  • Charleston
  • 4 Bedrooms
  • 2 Bathrooms
  • Sleeps 12
Casa Zoë | Grand Sparrow House

Summary:OP2026-07255OP2026-07256OP2026-07257Casa Zoë’s crown jewel, The James Sparrow House, is a grandiose Federal-style landmark reimagined for modern gatherings. Totally redesigned, it blends 19th-century craftsmanship with bold interiors and...

  • Charleston
  • 9 Bedrooms
  • 7 Bathrooms
  • Sleeps 27
Pool! | 2 Blocks to King St | Parthenon ...

Permit Number: 05086The Space: Two homes. Ten bedrooms. Walk to King Street.This broad Charleston getaway is designed for huge groups who want space to gather without sacrificing privacy. Tucked on a peaceful street just a 6-min. walk to King...

  • Charleston
  • 10 Bedrooms
  • 6 Bathrooms
  • Sleeps 20