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Charleston, SC 4+ Bedroom Vacation Rentals

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360 rentals found
Six on Cannon | 6BR Charleston Home + Pa...

Summary:Welcome to Six on Cannon, a roomy 6 bedroom 2 bathroom home ideally suited for families, friends, or get-togethers who want room, style, and downtown convenience together. Recently furnished and thoughtfully arranged, it gives you all the...

  • Charleston
  • 6 Bedrooms
  • 2 Bathrooms
  • Sleeps 16
Casa Zoë | Cottage Row – Side-by-Side...

Summary:OP2025-05857OP2025-05858Cottage Row is a rare Charleston find with two completely separate, next-door Casa Zoë cottages that together create the ideal setup for groups who want to be close but still have their own space. Tucked in the...

  • Charleston
  • 4 Bedrooms
  • 4 Bathrooms
  • Sleeps 10
The Inns | 18 bedrooms, Luxurious + Gran...

Summary:As part of the esteemed collection, The Inns, this striking 18-bedroom compound is located on Spring Street in the heart of Charleston. Ideal for huge groups, this entirely refreshed property combines two handsome Victorian homes with modern...

  • Charleston
  • 18 Bedrooms
  • 14 Bathrooms
  • Sleeps 30
Casa Bella - Your Oasis in the Heart of ...

Permit Number: 05934The Space: Introducing Casa Bella: A Charming Charleston Retreat with Ample Space and Serene YardLocated in the heart of Charleston, Casa Bella offers a freshly-remodeled haven boasting 6 bedrooms, 4 bathrooms, and divided into 2...

  • Charleston
  • 6 Bedrooms
  • 4 Bathrooms
  • Sleeps 11
Hot Tub • Private Courtyard • 1 Bloc...

Summary:✨ Welcome to The Palms of Charleston! ????☀️ Enormous Private Courtyard with Hot Tub???? 1 Block to King St! Walk to Charleston’s Finest Dining, Shopping & Nightlife???? Ideal for Generous Groups – Families, Wedding Guests...

  • Charleston
  • 7 Bedrooms
  • 4 Bathrooms
  • Sleeps 14
The Rutledge Avenue Inn Historic Charles...

Permit Number: 05608The Space: Rutledge Avenue Inn, Units A, B and C, is a handsomely restored 5-bedroom, 5-bath Charleston gem with two additional half baths, offering the ideal blend of privacy, appeal, and modern comfort. Guests savor exclusive...

  • Charleston
  • 5 Bedrooms
  • 5 Bathrooms
  • Sleeps 10
Charleston Vacation Rental with Yard!

This beautiful Charleston vacation rental offers the ideal destination for a family getaway! Located 17 miles from Folly Beach, this home lets you savor the sun and sand before heading back to relax in front of one of 6 Intelligent TVs. The...

  • Charleston
  • 4 Bedrooms
  • 2 Bathrooms
  • Sleeps 6
Trendy Charleston 4BR - Steps from King ...

Summary:Welcome to your Charleston getaway, a beautiful 4-bedroom home where architectural appeal meets modern style just steps from King Street. Ideal for families or groups wanting both design flair and outdoor comfort, this property gives you...

  • Charleston
  • 4 Bedrooms
  • 3 Bathrooms
  • Sleeps 9
Colorful Downtown House with Outdoor Spa...

Summary:This freshly refreshed, brand-new listing offers 4 bedrooms and 2 baths, thoughtfully designed with playful pops of color and loads of character. Created with groups in mind, the home features generous, comfortable seating throughout the...

  • Charleston
  • 4 Bedrooms
  • 2 Bathrooms
  • Sleeps 10
Whole House|Downtown|Sleeps 16

Summary:Welcome to The Ivory and Oak Lofts, a striking 8-bedroom, 6-bathroom historic home located in the heart of Charleston. This gorgeously restored property blends timeless appeal with modern amenities, offering an exceptional space for enormous...

  • Charleston
  • 8 Bedrooms
  • 6 Bathrooms
  • Sleeps 16
Newly Restored Historic Home, Close to K...

Welcome to 12 Cannon Street, Units A & B – a delightfully restored four-bedroom, six-bathroom Charleston-style home in the heart of the city. This combined listing is ideal for bigger families and groups seeking modern amenities within walking...

  • Charleston
  • 4 Bedrooms
  • 6 Bathrooms
  • Sleeps 12
Where Tranquility Blooms | Blossoms on C...

Permit Number: 06351The Space: Welcome to Blossoms on Cannon, a gorgeously restored two-story Charleston home designed for comfort, connection, and memorable group stays. With 5 bedrooms and 4 bathrooms, this cavernous getaway is ideal for up to 10...

  • Charleston
  • 5 Bedrooms
  • 4 Bathrooms
  • Sleeps 10
The Lord Ashley - Sleeps 8!

Our sun-filled home features an inviting open floor plan that includes two sitting rooms and a huge dining area with bar that leads into the cavernous chef's kitchen. The entirely equipped kitchen is complete with stainless steel appliances...

  • Charleston
  • 4 Bedrooms
  • 2 Bathrooms
  • Sleeps 8
Designer's Dream in Historic Charleston ...

Blue Haven – A Chic Boho Escape in the Heart of CharlestonLocated just steps from the city's vibrant cultural scene, Blue Haven is a thoughtfully designed 4-bedroom, 3.5-bath getaway that blends historic Charleston appeal with a breezy...

  • Charleston
  • 4 Bedrooms
  • 3 Bathrooms
  • Sleeps 8
Downtown Charleston - 4BR Luxurious Geta...

Summary:Discover this 4BR/4BA Charleston hideaway, ideally located just off King Street in the Crosstown neighborhood. Each bedroom offers a private en suite, with modern design, Intelligent TVs, and high-speed WiFi throughout. Appreciate a entirely...

  • Charleston
  • 4 Bedrooms
  • 4 Bathrooms
  • Sleeps 9
NEW! Private Home Downtown at Emerson Sq...

Summary:Welcome to your Full Private Home Retreat in Downtown Charleston! This striking 4-bedroom, 3.5-bathroom luxury residence is a newly constructed masterpiece, professionally furnished and designed with every detail in mind. Located in the...

  • Charleston
  • 4 Bedrooms
  • 3 Bathrooms
  • Sleeps 10
Crosstown @ King | Elegant & Modern 6BR ...

Summary:Feel Charleston in style at this 6BR, 4BA Crosstown getaway just one block from King Street. Designed for up to 14 guests, the home combines modern finishes with cavernous comfort. Savor multiple living areas, a entirely equipped kitchen...

  • Charleston
  • 6 Bedrooms
  • 4 Bathrooms
  • Sleeps 14
The Parthenon Suites | 2 Blocks to King ...

Permit Number: 05086The Space: After February 2026, savor a brand-new private pool in the enclosed backyard, photos coming soon!Feel the comfort and privacy of two elegantly appointed homes, ideal for enormous groups, families, or special...

  • Charleston
  • 10 Bedrooms
  • 6 Bathrooms
  • Sleeps 20