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Charleston, SC 4+ Bedroom Vacation Rentals

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355 rentals found
Charleston Charm - Downtown - 4 Bedroom

Summary:Welcome to Charleston Charm, your home away from home located in the historic Westside neighborhood. Ideal for families or groups, this newly refreshed 4-bedroom home offers space, comfort, and an ideal location just north of downtown. Steps...

  • Charleston
  • 4 Bedrooms
  • 2 Bathrooms
  • Sleeps 9
East 204 - Entire Home 1 Block to King!

East 204 is a splendid standalone two story home located one block to King Street. The home has a charming main floor boasting an open living, dining, and kitchen area. Just off the main living area, there is one bedroom with an ensuite bathroom...

  • Charleston
  • 4 Bedrooms
  • 3 Bathrooms
  • Sleeps 8
Downtown Historic Home Close to Neighbor...

Summary:Welcome to this vibrant downtown getaway! Originally constructed in 1905 and freshly modernized, this colorful home blends historic appeal with modern comfort. With eight uniquely styled bedrooms and eight gorgeously refreshed bathrooms...

  • Charleston
  • 8 Bedrooms
  • 4 Bathrooms
  • Sleeps 16
Southern Ease, Contemporary Flair | The ...

Permit Number: 06855The Space: Welcome to The Charleston, where timeless Southern appeal meets modern comfort. Constructed in 1852 and thoughtfully refreshed, this beautiful historic home offers a private getaway spanning the entire 2nd and 3rd...

  • Charleston
  • 4 Bedrooms
  • 3 Bathrooms
  • Sleeps 8
Guesthouse Charleston: SOUTH 105 A & B

Located peacefully on coveted Spring Street, this striking standalone duplex features eight roomy bedrooms and eight full bathrooms, just steps away from Cannon Green and just three blocks to historic King Street. Ideal for huge groups or...

  • Charleston
  • 8 Bedrooms
  • 9 Bathrooms
  • Sleeps 20
NEW Home | Close to DT & Beaches | 4 BR,...

Summary:Welcome to Coastal Comfort!Unwind in this bright and modern new construction home. It features a cavernous kitchen, four comfortable bedrooms, and a beach-inspired design. Appreciate the sizable backyard for gatherings, and make this your...

  • Charleston
  • 4 Bedrooms
  • 2 Bathrooms
  • Sleeps 10
‘Tropical Blue’ – Historic Home 5 ...

Summary:'The Tropical Blue' at The Blue Haven is a 5 min. walk to famed King Street. This refreshed historic home includes a modern kitchen, striking living area, and a traditional private piazza to lounge in the shade & watch the city go by.The...

  • Charleston
  • 4 Bedrooms
  • 4 Bathrooms
  • Sleeps 10
Guesthouse Charleston: WEST (242 B)

West 242 B is a striking standalone home located in the heart of the Cannonborough/Elliotborough neighborhood, just two blocks from historic King Street. This prime downtown Charleston location offers painless access to the best eateries, coffee...

  • Charleston
  • 4 Bedrooms
  • 3 Bathrooms
  • Sleeps 8
4 BR with Rooftop - Cozy Home near King ...

Welcome to the Holy City, and the historic southern appeal of the Charleston peninsula. Our Vacation Rental By Owner is located in handsome downtown Charleston and just mins. away from MUSC, the College of Charleston, and King Street’s shopping...

  • Charleston
  • 4 Bedrooms
  • 5 Bathrooms
  • Sleeps 12
Casa Zoë | Grand Federal Sparrow House ...

Summary:OP2025-05862Sparrow House is a stately Federal-style, National Register residence reimagined for modern group stays. This full-home Casa Zoë gem blends historic appeal—porches, millwork, heart pine floors—with bold, gallery-worthy...

  • Charleston
  • 4 Bedrooms
  • 3 Bathrooms
  • Sleeps 13
Six on Cannon | 6BR Charleston Home + Pa...

Summary:Welcome to Six on Cannon, a roomy 6 bedroom 2 bathroom home ideally suited for families, friends, or get-togethers who want room, style, and downtown convenience together. Recently furnished and thoughtfully arranged, it gives you all the...

  • Charleston
  • 6 Bedrooms
  • 2 Bathrooms
  • Sleeps 16
Charming Charleston Getaway

Welcome to your home away from home in the heart of Charleston`s vibrant Cannonborough-Elliottborough neighborhood! This roomy 4 bedroom, 3.5 bathroom getaway is ideal for families or groups of friends looking to discover all that this historic city...

  • Charleston
  • 4 Bedrooms
  • 3 Bathrooms
  • Sleeps 10
The Madison Compound- Entire Charleston ...

Encompass yourself in the history of Charleston by staying in this freshly remodeled 1890`s single home. The Madison Compound offers guests all the aesthetic features of a Charleston Single House from it sizable Piazzas, private roof top deck and...

  • Charleston
  • 6 Bedrooms
  • 7 Bathrooms
  • Sleeps 16
Charming 5 Bedroom House - 1 Block to Ki...

Summary:Feel Charleston in style at this 5BR, 4.5BA home where historic appeal meets modern design. Each king bedroom offers comfort, three with private en-suites. Gather in the cavernous living areas or prepare in the completely supplied kitchen...

  • Charleston
  • 5 Bedrooms
  • 4 Bathrooms
  • Sleeps 12
Crosstown @ King | Elegant & Modern 6BR ...

Summary:Feel Charleston in style at this 6BR, 4BA Crosstown getaway just one block from King Street. Designed for up to 14 guests, the home combines modern finishes with cavernous comfort. Appreciate multiple living areas, a completely equipped...

  • Charleston
  • 6 Bedrooms
  • 4 Bathrooms
  • Sleeps 14
The Inns | Grand 9BR Charleston Downtown...

Summary:Welcome to your Charleston gathering place where space meets luxury. This enormous 9 bedroom home is constructed for huge groups, offering eight full bathrooms to make everybody’s stay comfortable and convenient. Ideal for family...

  • Charleston
  • 9 Bedrooms
  • 8 Bathrooms
  • Sleeps 16
The Manor on Spring 91 B- Immaculately R...

The true Charleston experience awaits at The Manor at 91B Spring, a restored Victorian home in the heart of the city. The home offers 4 bedrooms plus a flex room with a queen Murphy bed, along with 4.5 bathrooms, including 3 ensuites. A bright, open...

  • Charleston
  • 4 Bedrooms
  • 4 Bathrooms
  • Sleeps 12
The Isla Suite: A Dream Getaway for Frie...

The Isla Suite: A Dream Getaway for FriendsThe Isla Suite is a vibrant first-floor getaway in striking Charleston, crafted for an memorable friends’ group hideaway. Positioned just steps from downtown’s premier drink bars, top-rated eateries...

  • Charleston
  • 4 Bedrooms
  • 2 Bathrooms
  • Sleeps 8