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Charleston, SC 4+ Bedroom Vacation Rentals

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359 rentals found
Downtown Charleston Home - 1 Block to Ki...

Summary:Welcome to your Charleston hideaway, a designer-refurnished home just one block from King Street that blends style, comfort, and an indoor-outdoor vibe. Ideal for friends or couples who want walkability, thoughtful design, and a backyard...

  • Charleston
  • 4 Bedrooms
  • 2 Bathrooms
  • Sleeps 12
The Gardenia House | Sleeps 20 | Multi-U...

Summary:Welcome to the Gardenia House in the Preserve, a distinguished luxury residence located in the heart of downtown Charleston. This charming property offers two exclusive suites within a cavernous layout of 7 bedrooms and 7 full baths, making...

  • Charleston
  • 7 Bedrooms
  • 7 Bathrooms
  • Sleeps 20
The Manor on Spring 91 B- Immaculately R...

The true Charleston experience awaits at The Manor at 91B Spring, a restored Victorian home in the heart of the city. The home offers 4 bedrooms plus a flex room with a queen Murphy bed, along with 4.5 bathrooms, including 3 ensuites. A bright, open...

  • Charleston
  • 4 Bedrooms
  • 4 Bathrooms
  • Sleeps 12
Full House w Bikes, Grill + Patio + Park...

Summary:This home has everything you need for the ideal group trip to Charleston. Located in the heart of Downtown in a safe, charming neighborhood, The Rose features six handsomely refreshed bedrooms, two full kitchens, and two cavernous living...

  • Charleston
  • 6 Bedrooms
  • 4 Bathrooms
  • Sleeps 16
Full Renovation of 1811 historical home....

Recently restored and only 2 blocks from the heart of the entertainment district of Upper King Street, Stay Cannon is the ideal landing place for your next trip to Charleston.Stay Cannon is a legally allowed vacation rental as required by Charleston...

  • Charleston
  • 6 Bedrooms
  • 6 Bathrooms
  • Sleeps 12
Southern Elegance Meets Charleston Charm...

Summary:Welcome to your serene Charleston getaway, where traditional Southern appeal meets the vibrant lifestyle of one of America's most celebrated cities. Located in a striking neighborhood adorned with age-old oak trees and sunlit avenues, our...

  • Charleston
  • 4 Bedrooms
  • 1 Bathrooms
  • Sleeps 8
Downtown Duplex - Coming St - Sleeps 20

Feel the timeless appeal of Charleston’s historic peninsula, the Holy City. Stay just mins. from MUSC, the College of Charleston, and the vibrant shopping, dining, and nightlife of King Street. From this ideally located downtown home, you’ll be...

  • Charleston
  • 6 Bedrooms
  • 4 Bathrooms
  • Sleeps 16
Oak Loft Downtown | Restored Masterpiece

Summary:Welcome to The Oak Loft, an exceptional 4-bedroom, 3-bathroom top floor unit in the heart of Downtown Charleston. With its distinctive design and creative flair, this one-of-a-kind space offers an inspiring getaway! Located just steps from...

  • Charleston
  • 4 Bedrooms
  • 3 Bathrooms
  • Sleeps 8
The Soiree by Charleston Vacays-New Buil...

Feel the epitome of modern Charleston living in this striking 5-bedroom, 5-bathroom vacation rental, aptly named The Soiree. Located in the heart of downtown Charleston, this extravagant abode offers an unbeatable location. Upper King Street, just a...

  • Charleston
  • 5 Bedrooms
  • 5 Bathrooms
  • Sleeps 14
The Blue Angel-In Ground Pool

Welcome to your Charleston-area getaway! This cavernous Home is 2,300 square feet of comfortable living space designed for calming, entertaining, and making memories. The home features a bright open layout with vaulted ceilings, modern floor, and...

  • Charleston
  • 7 Bedrooms
  • 3 Bathrooms
  • Sleeps 13
Designer Chic 6BR Full Downtown Charlest...

Feel the timeless appeal of Charleston’s historic peninsula, the Holy City. Stay just mins. from MUSC, the College of Charleston, and the vibrant shopping, dining, and nightlife of King Street. From this ideally located downtown home, you’ll be...

  • Charleston
  • 6 Bedrooms
  • 4 Bathrooms
  • Sleeps 14
Private Pool & Historic Home ‘Summer H...

Summary:A short walk to famed King Street, 'The Summer Haze' is a private Charleston home, with private pool! Renovated with modern amenities, experience the appeal of a traditional Charleston home, with comfortable bedrooms & en suite bathrooms...

  • Charleston
  • 4 Bedrooms
  • 4 Bathrooms
  • Sleeps 11
The Queens Palace | 8 Bedrooms in Charle...

Permit Number: 05553The Space: Welcome to The Queen’s Palace, your private Charleston getaway made up of three elegantly restored historic homes in the heart of the Cannonborough–Elliotborough neighborhood. With eight bedrooms, eight bathrooms...

  • Charleston
  • 8 Bedrooms
  • 8 Bathrooms
  • Sleeps 16
The Elliotborough Suite | Prime 4BR Near...

Summary:Welcome to your Charleston luxury stay where privacy, elegance and convenience converge. This four-master home is ideal for groups or families who appreciate fresh design and want independent space for everybody. You will savor generous en...

  • Charleston
  • 4 Bedrooms
  • 4 Bathrooms
  • Sleeps 12
Downtown Duplex - Rutledge Avenue

Feel the timeless appeal of Charleston’s historic peninsula, the Holy City. Stay just mins. from MUSC, the College of Charleston, and the vibrant shopping, dining, and nightlife of King Street. From this ideally located downtown home, you’ll be...

  • Charleston
  • 4 Bedrooms
  • 2 Bathrooms
  • Sleeps 12
Near Citadel Mall! Extended Getaway 8 Mi...

1/2 Mi to Movie Theater & Dining | Suburban Neighborhood | 15 Mi to Folly BeachSwap the snow for the South Carolina sunshine! This Charleston vacation rental offers the ideal base for snowbirds and those seeking long-term accommodations. Kick off...

  • Charleston
  • 4 Bedrooms
  • 2 Bathrooms
  • Sleeps 8
Rooftop • Hot Tub • Parking • 3 Bl...

Summary:✨ Welcome to Camellias on Cannon – Suite B! ????☀️ Private Rooftop Deck???? Courtyard with Hot Tub???? Ideal for Enormous Groups – Families, Wedding Guests, Bachelor(ettes) & Work Retreats???? 3 Blocks to King St! Walk to...

  • Charleston
  • 4 Bedrooms
  • 3 Bathrooms
  • Sleeps 8
Boutique Home & Resort Pool ‘The Palms...

Summary:A short walk from King St. 'The Palms' is a roomy private historic property. Rare downtown amenities include the marvelous shared Spring Island Collection Pool. The property offers an open kitchen & living area, opening directly to...

  • Charleston
  • 4 Bedrooms
  • 4 Bathrooms
  • Sleeps 13