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Charleston, SC 4+ Bedroom Vacation Rentals

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350 rentals found
Great for Groups | Private Patio | The Z...

Permit Number: 06281The Space: Feel downtown Charleston at its best in Zeus, a cavernous and modren second-floor getaway ideal for families or enormous groups. With 5 bedrooms and 4.5 bathrooms, there’s plenty of room for everybody to relax and...

  • Charleston
  • 5 Bedrooms
  • 4 Bathrooms
  • Sleeps 12
Charleston Abode | Downtown, 1 Block fro...

Summary:Welcome to Charleston Abode, a luminous 2-bedroom getaway just one block from King Street where historic appeal meets modern comfort. Designed for couples or modest groups, this home offers airy interiors, chic details, and rare outdoor...

  • Charleston
  • 6 Bedrooms
  • 4 Bathrooms
  • Sleeps 14
The Mary Scott and Daniel Legare House

Permit Number: 05793The Space: Welcome to your Charleston getaway at 11 George Street!TThis appealing and roomy home features 5 elegantly appointed bedrooms and 3 full bathrooms, making it an ideal getaway for families, friends, or bigger groups...

  • Charleston
  • 5 Bedrooms
  • 3 Bathrooms
  • Sleeps 16
The Inns Charming 5BR/3BA Heart of Downt...

Summary:Welcome to your Charleston hideaway, a thoughtfully designed 5-bedroom, 3-bathroom getaway spanning two separate units in one property. Ideal for families or groups, this home offers the rare combination of double kitchens and living rooms...

  • Charleston
  • 5 Bedrooms
  • 3 Bathrooms
  • Sleeps 14
The Gardenia House | Sleeps 20 | Multi-U...

Summary:Welcome to the Gardenia House in the Preserve, a distinguished luxury residence located in the heart of downtown Charleston. This opulent property offers two exclusive suites within a roomy layout of 7 bedrooms and 7 full baths, making it...

  • Charleston
  • 7 Bedrooms
  • 7 Bathrooms
  • Sleeps 20
The Quad at 493 - 4 Suites - Right on Ki...

Permit Number: 004141The Space: Welcome to 493 Luxury Suites! These handsomely appointed units are found on the second floor of a historic building on King Street (above Sewing Down South, as seen on “Southern Charm”).Step into the building...

  • Charleston
  • 8 Bedrooms
  • 8 Bathrooms
  • Sleeps 24
Luxe 5BR w/ Heated Pool~1 Block to King~...

Welcome to The Lowcountry House, a charmingly restored 5-bedroom luxury getaway in the heart of Downtown Charleston with a Private Heated Pool. Originally constructed in the 1860s, this home exudes Lowcountry appeal with handcrafted details and...

  • Charleston
  • 5 Bedrooms
  • 4 Bathrooms
  • Sleeps 12
1 Block to King St | Plunge Pool | Sleep...

Summary:Feel luxury at The Pink Palm, a gorgeous new construction 4-bedroom, 4-bathroom getaway in downtown Charleston finished in APR 2025. Savor cavernous living areas, fashonable baths, and a entirely equipped kitchen. Unwind in the private...

  • Charleston
  • 4 Bedrooms
  • 4 Bathrooms
  • Sleeps 10
Blue Magnolia | Perfect for Large Groups

Summary:Discover Blue Magnolia, your chic and roomy Charleston getaway. This 7BR/4BA home combines classic Southern appeal with modern comfort, making it ideal for families or groups. Unwind on the inviting front porch, soak in the airy interiors...

  • Charleston
  • 7 Bedrooms
  • 4 Bathrooms
  • Sleeps 17
2 Luxury Houses w/ Patios | 1 Block from...

Summary:Discover luxury pair of completely remodeled luxury homes ideal for a huge group, located next door to each other just moments from King St. Indulge in beautiful interiors awash with natural light from wrap-around windows. These Charleston...

  • Charleston
  • 8 Bedrooms
  • 7 Bathrooms
  • Sleeps 20
 New Upscale 4 Bedroom, King Beds , Priv...

Your Charleston adventure begins at this enchanting 4-bedroom home.Stay Cannon is a legally allowed vacation rental as required by Charleston City Ordinance and is located in the trendy Cannonborough/Elliotborough neighborhood.Great for family and...

  • Charleston
  • 4 Bedrooms
  • 4 Bathrooms
  • Sleeps 10
Casa Fuego - Suites D and E

Permit Number: 05792The Space: Welcome to Casa Fuego — Suites D & E!Ideal for bigger groups traveling together, this roomy 4-bedroom, 2-bath getaway offers the best of downtown Charleston living with the comfort of two private apartments...

  • Charleston
  • 4 Bedrooms
  • 2 Bathrooms
  • Sleeps 10
New Build - Steps to King Street

Feel the epitome of modern Charleston living in this impressive, brand new, 5-bedroom, 5-bathroom vacation rental apartment, aptly named The Chateau. Located in the heart of downtown Charleston, this extravagant abode offers an unbeatable location...

  • Charleston
  • 5 Bedrooms
  • 5 Bathrooms
  • Sleeps 14
Modernized 5BR Family Home?Tranquil Pati...

This handsome 5-bedroom, 2.5-bathroom home is a true gem, located on one of the quietest streets in Charleston. With freshly refreshed bathrooms, resurfaced floors, and a cavernous, open floor plan, this home is ideal for families or professionals...

  • Charleston
  • 5 Bedrooms
  • 3 Bathrooms
  • Sleeps 10
Luxury 8BR/6.5BA Downtown w Outdoor Spac...

Summary:Bring everybody together in this roomy 8BR/6.5BA Charleston home featuring two kitchens, dual living areas, and chic design throughout. Just 4 blocks from King Street, this getaway offers modern amenities with historic appeal, high-speed...

  • Charleston
  • 8 Bedrooms
  • 6 Bathrooms
  • Sleeps 18
EAST 46 G & H - 2 Units, Connected Inter...

Two elegant adjoining apartments offering a total of 5 bedrooms, 5 bathrooms, 2 full kitchens, and 2 roomy living rooms, making them ideal for bigger groups or families seeking both space and comfort. Located just one block from King Street in...

  • Charleston
  • 5 Bedrooms
  • 5 Bathrooms
  • Sleeps 14
Lowcountry Family Getaway-A Charleston A...

RENOVATED, ROOMY & READY! This cavernous 3238 square ft, upgraded home is a exceptional value for your family beach vacation, golf trip, or wedding season get together with friends!! No matter the occasion, this home will surely host you and your...

  • Charleston
  • 4 Bedrooms
  • 3 Bathrooms
  • Sleeps 18
The Parthenon Suites | 2 Blocks to King ...

Permit Number: 05086The Space: After February 2026, appreciate a brand-new private pool in the enclosed backyard, photos coming soon!Feel the comfort and privacy of two attractively appointed homes, ideal for sizable groups, families, or special...

  • Charleston
  • 10 Bedrooms
  • 6 Bathrooms
  • Sleeps 22