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Charleston, SC 4+ Bedroom Vacation Rentals

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361 rentals found
Designer's Dream in Historic Charleston ...

Blue Haven – A Chic Boho Escape in the Heart of CharlestonLocated just steps from the city's vibrant cultural scene, Blue Haven is a thoughtfully designed 4-bedroom, 3.5-bath getaway that blends historic Charleston appeal with a breezy...

  • Charleston
  • 4 Bedrooms
  • 3 Bathrooms
  • Sleeps 8
Grand 18bd House w. Luxury Finishes + Pa...

Summary:As part of the esteemed collection, The Heirloom, this impressive 18-bedroom compound is located on Spring Street in the heart of Charleston. Ideal for huge groups, this completely modernized property combines two extravagant Victorian homes...

  • Charleston
  • 18 Bedrooms
  • 15 Bathrooms
  • Sleeps 30
Sunny Haven Retreat near Folly w/ Backya...

Discover a comfortable coastal escape conveniently located just mins. from Folly Beach or Downtown Charleston! Our beautiful 4br/2ba home is the ideal getaway, featuring a refreshed interior that has been charmingly decorated. Savor the outdoors in...

  • Charleston
  • 4 Bedrooms
  • 2 Bathrooms
  • Sleeps 8
4bd House Downtown w. Rooftop Terrace + ...

Summary:Feel Charleston from the Palmetto on Spring, a refreshed 3-floor home in the beautiful Cannonborough neighborhood. Ideal for groups, this 4-bedroom, 4.5-bath getaway comfortably sleeps 10+ and features a private rooftop terrace and parking...

  • Charleston
  • 4 Bedrooms
  • 5 Bathrooms
  • Sleeps 10
6 Bedrooms! One Block to King Street!

Summary:Welcome to your Charleston gathering home, a six-bedroom property just one block from King Street that offers space, character, and plenty of outdoor appeal. Ideal for sizable families or groups who want walk-ability, historic details, and...

  • Charleston
  • 6 Bedrooms
  • 4 Bathrooms
  • Sleeps 14
 Upscale House, King Beds, Private Baths...

Your Charleston adventure begins at this enchanting 4-bedroom home.Stay Cannon is a legally allowed vacation rental as required by Charleston City Ordinance and is located in the trendy Cannonborough/Elliotborough neighborhood. Our license number is...

  • Charleston
  • 4 Bedrooms
  • 4 Bathrooms
  • Sleeps 10
Revitalized Historical Southern Residenc...

Summary:Ideal for a enormous family! Just one block away from upper King Street, the new epicenter of the city's acclaimed restaurant and nightlife district. Appreciate some of Charleston's best local dining, all located within just a few blocks of...

  • Charleston
  • 4 Bedrooms
  • 3 Bathrooms
  • Sleeps 10
Lowcountry Charm | 4BR Spring St. Home w...

Welcome to the Holy City, and the historic southern appeal of the Charleston peninsula. Our Vacation Rental By Owner is located in elegant downtown Charleston and just mins. away from MUSC, the College of Charleston, and King Street’s shopping and...

  • Charleston
  • 4 Bedrooms
  • 3 Bathrooms
  • Sleeps 11
Spring Complex - Walk to King St

Appreciate the convenience of this downtown triplex. This home is located in a outstanding neighborhood just a 6-7 min. walk to King Street, 1-2 min. walk to MUSC campus, and a short ride to the historical district and Rainbow Row. Booking this...

  • Charleston
  • 4 Bedrooms
  • 4 Bathrooms
  • Sleeps 12
Luxury 4 Bedroom On King St Parking Outd...

Feel the timeless appeal of Charleston’s historic peninsula, the Holy City. Stay just mins. from MUSC, the College of Charleston, and the vibrant shopping, dining, and nightlife of King Street. From this ideally located downtown home, you’ll be...

  • Charleston
  • 4 Bedrooms
  • 2 Bathrooms
  • Sleeps 10
Family and Pet-Friendly Retreat, 5BR Nea...

This property is new to Vacation Rental By Owner but we are well established hosts with our other property on vrbo and @irbnb with super host status and many reviews.Welcome to your home away from home! Our roomy 5-bedroom, 3-bath home is ideal for...

  • Charleston
  • 5 Bedrooms
  • 2 Bathrooms
  • Sleeps 10
New design & construction, 6 Bed, 6 EnSu...

Welcome to 183 Saint Philip Street, your chic haven in the heart of Charleston! This new construction offers a prime location, placing you steps away from the city's vibrant attractions & best eateries. Each bedroom features 55" Samsung TVs ...

  • Charleston
  • 6 Bedrooms
  • 6 Bathrooms
  • Sleeps 16
The Chapel | Estate 5BR Gem in Downtown ...

Summary:Welcome to your Charleston sanctuary, a charmingly preserved 5-bedroom gem attractively located in the heart of downtown. Boasting historic architecture, broad common rooms, and thoughtful modern amenities, this home is ideal for families...

  • Charleston
  • 5 Bedrooms
  • 4 Bathrooms
  • Sleeps 12
Whole House, Downtown, Sleeps 16

Summary:Welcome to The Ivory and Oak Lofts, a gorgeous 8-bedroom, 6-bathroom historic home located in the heart of Charleston. This attractively restored property blends timeless appeal with modern amenities, offering an exceptional space for huge...

  • Charleston
  • 8 Bedrooms
  • 6 Bathrooms
  • Sleeps 16
Cozy Home w/ Yard ~ 9 Mi to Dtwn Charles...

Feel the best of the Charleston area with a stay at this beautiful 4-bedroom, 2-bathroom vacation rental home. Boasting ample natural lighting, a completely equipped kitchen for preparing home-cooked meals, and a fenced-in yard for your furry...

  • Charleston
  • 4 Bedrooms
  • 2 Bathrooms
  • Sleeps 8
Guesthouse Charleston: WEST (242 C)

West 242 C is a appealing standalone home located in the heart of the Cannonborough/Elliotborough neighborhood, just two blocks from historic King Street. This prime downtown Charleston location offers simple access to the best eateries, coffee...

  • Charleston
  • 4 Bedrooms
  • 3 Bathrooms
  • Sleeps 8
Guesthouse Charleston: SOUTH (82 B)

82 - B is a roomy second-floor apartment offering ample comfort for your entire group, featuring two king beds, three queen beds, and four and a half bathrooms. Located just a fast three-block walk from King Street, you'll be within simple reach of...

  • Charleston
  • 4 Bedrooms
  • 4 Bathrooms
  • Sleeps 10
Spacious 4BR Retreat w/ Huge Yard, Outdo...

Cavernous 4BR home (2x King, 2x Queen) just 12 mins. from Folly Beach and 8 mins. to downtown Charleston. Appreciate a humongous fenced yard, outdoor shower, fire pit, and a huge dining table with umbrella and fan—ideal for warm evenings. Located...

  • Charleston
  • 4 Bedrooms
  • 2 Bathrooms
  • Sleeps 8