Charleston-SC.com logo

Charleston, SC 2+ Bedroom Vacation Rentals

Filter 2+ Bedroom Charleston Properties by: Company | Oceanfront | Pet-Friendly | or choose different a Area or Bedrooms
No company options available.
Bedrooms:
1071 rentals found
Guesthouse Charleston: SOUTH (105 B)

Recently Renovated in 2024! Located on the second floor of a gorgeous two-unit duplex, this four bedroom, four and a half bathroom home is located on the coveted Spring Street, just steps away from Cannon Green. Feel comfort and style as you step...

  • Charleston
  • 4 Bedrooms
  • 4 Bathrooms
  • Sleeps 10
East 42 A & B - Entire Ground Floor, 2 U...

East 42 A & B is the combined listing for the two homes below. These two pretty homes can be connected via the fire door in the hallway creating a alluring five bedroom, five bathroom, with a queen murphy bed for flex linens, and two private parking...

  • Charleston
  • 5 Bedrooms
  • 5 Bathrooms
  • Sleeps 12
Spacious 3bd, Beach Oasis with Water Vie...

Summary:Welcome to On Folly Time, where peaceful water vistas, salty breezes, and a peaceful private road set the tone for your stay. Thoughtfully designed for couples, families, and friends, this coastal getaway blends modern comfort with laid-back...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 7
Downtown Historic Home Steps to King St

Summary:Welcome to this striking Southern bungalow, where classic elegance meets modern comfort. This enchanting home features four roomy bedrooms and two gorgeously appointed bathrooms, ideal for family living or entertaining guests. The inviting...

  • Charleston
  • 4 Bedrooms
  • 2 Bathrooms
  • Sleeps 13
Trendy Charleston 4BR - Steps from King ...

Summary:Welcome to your Charleston getaway, a fresh 4-bedroom home where architectural appeal meets modern style just steps from King Street. Ideal for families or groups wanting both design flair and outdoor comfort, this property gives you exposed...

  • Charleston
  • 4 Bedrooms
  • 3 Bathrooms
  • Sleeps 9
Newly Renovated 4BR DT, Walkable!

Summary:Welcome to your Charleston escape, a beautiful 4-bedroom getaway where timeless craftsmanship meets modern comfort. With gleaming pine floors, intricate moldings, and opulent design details throughout, this home offers the ideal blend of...

  • Charleston
  • 4 Bedrooms
  • 5 Bathrooms
  • Sleeps 10
The Gardenia House | Unit A | Sleeps 7

Summary:Welcome to the Gardenia House in the Preserve, a refined luxury suite in downtown Charleston featuring 3 roomy bedrooms and 3 full baths. Designed for flexibility and comfort, this splendid suite can be rented separately or combined with the...

  • Charleston
  • 3 Bedrooms
  • 3 Bathrooms
  • Sleeps 7
Quarters on Spring-Rare CHS Retreat for ...

Welcome to The Quarters on Spring, an exceptionally cavernous and gorgeously refreshed Charleston hideaway located just mins. from the heart of downtown. It is rare to find a home this huge, this updated, and this beautiful in such a prime location...

  • Charleston
  • 6 Bedrooms
  • 4 Bathrooms
  • Sleeps 12
Only 2 Blocks to King! | The Blue Note

Permit Number: OP2025-06608The Space: Live like a local at Blue Note, our bright and welcoming two-story Charleston home designed for comfort, connection, and painless city living. Ideal for groups of up to eight, the home offers three bedrooms...

  • Charleston
  • 3 Bedrooms
  • 3 Bathrooms
  • Sleeps 7
Two Blocks to King Street | Sunflower Su...

Permit Number: 06698The Space: Welcome to The Sunflower Suite, a warm and inviting historic Charleston home located in the heart of downtown, thoughtfully designed for up to four guests to relax and appreciate the city together!Bedrooms ...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 4
The Trio at 493 - 3 Suites - On King!

Permit Number: 004141The Space: Welcome to 493 Luxury Suites! These gorgeously appointed units are found on the second floor of a historic building on King Street (above Sewing Down South, as seen on “Southern Charm”).Step into the building...

  • Charleston
  • 6 Bedrooms
  • 6 Bathrooms
  • Sleeps 18
Boho Haven in CHS | Southern Shangri-La ...

Permit Number: 07358The Space: Welcome to Southern Shangri-La on Coming, a tropical-inspired urban getaway tucked just off Coming Street in the heart of downtown Charleston!This second-floor apartment offers about 700 square feet of bright...

  • Charleston
  • 2 Bedrooms
  • 1 Bathrooms
  • Sleeps 4
La Casita, La Casita| Cozy Retreat Close...

Step into the wide open living room, seamlessly connected to a striking kitchen that overlooks the space, inviting you to come together and create lasting memories. The two gorgeous bathrooms feature sleek pebble stone floors and sliding glass...

  • Charleston
  • 3 Bedrooms
  • 3 Bathrooms
  • Sleeps 7
Charming Waterfront Cottage only 2 miles...

Charmingly-restored 1920's bungalow with heart-pine floors and tongue-and-grove wood walls and ceilings. This bungalow is a must for a comfortable and calming visit to Charleston, located on a peaceful country lane yet only two miles to Historic...

  • Charleston
  • 3 Bedrooms
  • 3 Bathrooms
  • Sleeps 6
Modernized 5BR Family Home?Tranquil Pati...

This delightful 5-bedroom, 2.5-bathroom home is a true gem, located on one of the quietest streets in Charleston. With freshly refreshed bathrooms, resurfaced floors, and a cavernous, open floor plan, this home is ideal for families or professionals...

  • Charleston
  • 5 Bedrooms
  • 3 Bathrooms
  • Sleeps 10
Beautifully Furnished  Townhouse  on Jam...

Welcome to our attractively furnished 1300 square-foot 3 bedroom 2 story townhouse, extremely convenient, yet private neighborhood on James Island. We just completely furnished our second home with all new appliances, furnishings, tv's, everything...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 5
The Fig House on Spring · Walk to King ...

Stay at The Fig House on Spring, a historic Charleston downstairs apartment with 3 bedrooms, 2 baths, and room for 8 guests. Appreciate one off-street parking spot, a full kitchen, private patio, and an simple walk to King Street dining, shopping...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 8
Vibrant Charm & Dining Pleasures | The H...

Permit Number: 06776The Space: Welcome to the Hurricane Suite, a serene ground-floor getaway in the heart of Charleston’s Medical District near the Medical University of South Carolina!This thoughtfully designed two-bedroom, one-bath apartment...

  • Charleston
  • 2 Bedrooms
  • 1 Bathrooms
  • Sleeps 5