Charleston-SC.com logo

Charleston, SC 2+ Bedroom Vacation Rentals

Filter 2+ Bedroom Charleston Properties by: Company | Oceanfront | Pet-Friendly | or choose different a Area or Bedrooms
No company options available.
Bedrooms:
1058 rentals found
Whimsical Historic Retreat! | Globetrott...

Permit Number: 07176The Space: Welcome to Globetrotter – Suite C — a bright, roomy first-floor getaway in the heart of downtown. With 2 bedrooms, 2 ensuite baths, and an open-concept layout, it’s a comfortable home base for up to 4...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 4
Spacious - Private 2 brs, 2 baths

City of Charleston Certificate of Operation Permit # OP2025-068871st floor of a duplex. 1250 SF. The bedrooms (and full bathrooms) are located on opposite sides of the single floor unit . Extensive living room, fireplace , intelligent tv with...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 4
EAST 44 - Entire Home, Only 1 Block to K...

East 44 is a handsomely restored historic home located in the vibrant Cannonborough/Elliotborough neighborhood. Just steps away, you'll find local favorites like Chubby Fish and Island Provisions, beautiful stores such as The Tiny Tassel and Hermosa...

  • Charleston
  • 4 Bedrooms
  • 4 Bathrooms
  • Sleeps 10
Experience Folly Life & Water Views Quie...

Quiet top floor condo located between two bridges with spectacular saltwater tidal vistas located on a friendly neighborhood road. One mile to the Folly Beach and only ten miles to Downtown Charleston. Unwind after a day at the beach on the outdoor...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 4
Plunge Pool|Downtown Oasis|Close to Bars...

Summary:Welcome to The Sullivan & Palm, a delightfully restored Victorian home in the heart of downtown Charleston. This roomy 5-bedroom getaway blends historic appeal with modern amenities, featuring beautiful living spaces, a chef’s kitchen, and...

  • Charleston
  • 5 Bedrooms
  • 3 Bathrooms
  • Sleeps 12
Waterfront Gem in the heart of James Isl...

Summary:Located in the serene environment of James Island, our waterfront property offers a secluded hideaway that feels like a world apart, yet remains connected to everything you need. This newly constructed two-bedroom, two-bathroom unit provides...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 5
Classic Home - 5 Star Location - Histori...

Summary:Feel Charleston appeal in this 4BR, 3BA home in the heart of the Historic District. With a Walk Score of 98, you’re just blocks from the iconic City Market and steps to King Street’s top stores, eateries, and rooftops.Tag us in your...

  • Charleston
  • 4 Bedrooms
  • 3 Bathrooms
  • Sleeps 8
Historic Charleston Right Outside Your F...

One of four residences in this 1870s-era historic modernized property, the 1,500-square-foot "Jasper Suite" residence offers you a comfortable getaway. Blending the best of old and new, this historic home has been completely refurbished with modern...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 4
Historic Charleston Charm

Summary:Discover this elegantly refreshed 1830s residence just six blocks from King Street. Historic Charleston Charm blends original period architecture with modern amenities, creating a warm and inviting base for your stay. Ideal for those who...

  • Charleston
  • 2 Bedrooms
  • 1 Bathrooms
  • Sleeps 5
Modern house in North Charleston

Welcome to your home away from home in North Charleston! This striking home offers 3 comfortable bedrooms, modern and entirely equipped kitchen. Located in a peaceful and safe neighborhood, close to local attractions: 13 min from the airport, 15 min...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 8
B1 at Saint Philip Square, One Block to ...

Welcome to Saint Philip Square, an award-winning collection of historic homes spanning nearly one city block of downtown Charleston. The Adams Bennett House at 174 B#1 Saint Philip Street is a 4-bed 4-bath first floor gem that blends modern comfort...

  • Charleston
  • 4 Bedrooms
  • 4 Bathrooms
  • Sleeps 10
Guesthouse Charleston: WEST (242 B & C)

West 242 B and 242 C are two beautiful standalone homes located in the heart of Charleston's vibrant Cannonborough/Elliotborough neighborhood, just two blocks from historic King Street. This prime location offers simple access to Charleston's best...

  • Charleston
  • 8 Bedrooms
  • 6 Bathrooms
  • Sleeps 16
Charleston Charmer - South of Broad

The Place: This Charleston Charmer is located in the coveted South of Broad / Harleston Village location.  Located in the heart of downtown, right across from Colonial Lake, a short walk to King Street, MUSC, Roper Hospital, College of...

  • Charleston
  • 2 Bedrooms
  • 3 Bathrooms
  • Sleeps 4
King Street- Historic Renovation w/ Park...

Summary:Step into Charleston history with this attractively refreshed 2-bedroom first-floor duplex, featuring original fireplaces over 100 years old, exposed beams, and thoughtfully updated interiors. Located right on King Street with a Walk Score...

  • Charleston
  • 2 Bedrooms
  • 1 Bathrooms
  • Sleeps 5
Just Blocks from King St | Sweetgrass (S...

Permit Number: 06474The Space: Welcome to Sweetgrass (Unit A), a light and airy first floor condo designed for comfort and simple living just steps from Spring Street. Ideal for up to four guests, this inviting home offers a casual Charleston...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 4
New 2-bedroom1 bath detached guest house...

Our new detached guest home is a cavernous 2 bedroom/1 bath rental located near some of the best areas of Charleston. The guest home is located just 7 mins. from the restaurant/bars, stores, and Atlantic Ocean of striking Folly Beach and 15 mins. to...

  • Charleston
  • 2 Bedrooms
  • 1 Bathrooms
  • Sleeps 6
5BR Sleeps 10 | Entire Home | 2 Kitchens...

Summary:The Quartiers Charlestonian are a blend of historic appeal and modern luxury featuring five queen bedrooms and three baths, two private kitchens and laundry units in which were thoughtfully remodeled. These adjoining historic suites provide...

  • Charleston
  • 5 Bedrooms
  • 3 Bathrooms
  • Sleeps 10
Suite Magnolia-Hot Tub-Pet Friendly, Min...

Welcome to Suite Magnolia, a gorgeous Charleston! We're delighted to offer you a comfortable stay with two bedrooms that can conveniently accommodate up to six guests. The main bedroom features a cozy king-size bed, and the second guest room...

  • Charleston
  • 2 Bedrooms
  • 1 Bathrooms
  • Sleeps 6