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Charleston, SC 2+ Bedroom Vacation Rentals

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1064 rentals found
Downtown Historic Home Close to Neighbor...

Summary:Welcome to this vibrant downtown getaway! Originally constructed in 1905 and newly remodeled, this colorful home blends historic appeal with modern comfort. With eight uniquely styled bedrooms and eight delightfully refreshed bathrooms...

  • Charleston
  • 8 Bedrooms
  • 4 Bathrooms
  • Sleeps 16
Pet-Friendly +Historic Charm & Modern Co...

Map House – Historic Charm Meets Modern Luxury in Downtown CharlestonJust blocks from the lively Upper King District, Map House is a handsomely restored 3-bedroom, 2-bathroom Charleston Single home with double piazzas, original architectural...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 6
Renovated 3BR Apartment 1 Block to King ...

Feel the timeless appeal of Charleston’s historic peninsula, the Holy City. Stay just mins. from MUSC, the College of Charleston, and the vibrant shopping, dining, and nightlife of King Street. From this ideally located downtown home, you’ll be...

  • Charleston
  • 3 Bedrooms
  • 3 Bathrooms
  • Sleeps 8
Lowcountry Charm | 4BR Spring St. Home w...

Welcome to the Holy City, and the historic southern appeal of the Charleston peninsula. Our Vacation Rental By Owner is located in handsome downtown Charleston and just mins. away from MUSC, the College of Charleston, and King Street’s shopping...

  • Charleston
  • 4 Bedrooms
  • 3 Bathrooms
  • Sleeps 11
Bright 2bd w. Chef's Kitchen, 1 Block to...

Summary:Bright, open-concept spaces invite you to relax and reconnect, while every bedroom features its own private en-suite bath for the ideal blend of comfort and privacy. Your ideal Charleston stay starts here.The Space:Unwind and recharge in...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 4
In the Heart of King Street | Hampton Su...

Permit Number: 004141The Space: Welcome to 493 Suites, your ideal group hideaway on iconic King Street. Located on the second floor of a attractively restored historic building—right above Sewing Down South, featured on Southern Charm—this...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 10
Hot Tub • Rooftop • Parking • Walk...

Summary:Welcome to Camellias on Cannon!☀️ Private Rooftop + Courtyard & Hot Tub???? 3 Blocks to King St – Walk to Charleston’s Finest Dining, Shopping & Nightlife???? Ideal for Generous Groups – Families, Weddings, & Work Retreats???...

  • Charleston
  • 8 Bedrooms
  • 7 Bathrooms
  • Sleeps 16
The Carriage Houses | Historic Charlesto...

Permit Number: 06973The Space: Welcome to this striking 2,200-square-foot getaway, thoughtfully combining two historic homes—the Kitchen House and Carriage House—into one inviting four-bedroom escape. Ideal for families, groups of friends, or...

  • Charleston
  • 4 Bedrooms
  • 3 Bathrooms
  • Sleeps 8
The Plunge at King Street w/ Private Poo...

Summary:Feel the The Plunge on King Street, a freshly modernized second-floor suite just one block from King Street. This historic gem blends Charleston appeal with sleek modern luxury. Appreciate exclusive access to a private plunge pool, a rare...

  • Charleston
  • 4 Bedrooms
  • 4 Bathrooms
  • Sleeps 10
The Chapel | Grand 8BR Charmer - Walkabl...

Summary:Welcome to The Chapel, a elegantly restored 8-bedroom gem in Charleston where character, comfort and convenience come together. Ideal for huge families or groups, this home offers roomy common areas, opulent design details and a location...

  • Charleston
  • 8 Bedrooms
  • 8 Bathrooms
  • Sleeps 16
Exclusive Low Country Island Estate Exce...

The Island Oak is appealingly located to major tourist attractions in Charleston. From our location, the historic district is a 10 min. drive , Folly Beach is 5 miles away and multiple pro link golf coarse to include the Ocean Coarse at Kiawah...

  • Charleston
  • 3 Bedrooms
  • 1 Bathrooms
  • Sleeps 6
Designer Suite in the Heart of Charlesto...

Immerse yourself in Charleston`s vibrant culture from this striking two-bedroom suite, meticulously designed by a professional interior designer. This light-filled haven blends modern comfort with antique appeal, boasting gorgeous artwork and a...

  • Charleston
  • 2 Bedrooms
  • 1 Bathrooms
  • Sleeps 4
Only 2 Blocks to King! | The Blue Note

Permit Number: OP2025-06608The Space: Live like a local at Blue Note, our bright and welcoming two-story Charleston home designed for comfort, connection, and painless city living. Ideal for groups of up to eight, the home offers three bedrooms...

  • Charleston
  • 3 Bedrooms
  • 3 Bathrooms
  • Sleeps 7
Vacation Villa 5 mins to King ‘The Roy...

Summary:Vacation Villa 5 min. walk to King St, in the heart of downtown Charleston. This tropical getaway offers sleek design, soaring 25’ ceilings, open first floor kitchen & living room, and roomy bedrooms with en-suite spa bathrooms. The Palm...

  • Charleston
  • 3 Bedrooms
  • 5 Bathrooms
  • Sleeps 8
Ivy Manor | DT Oasis + Carriage House!

Summary:Welcome to your Charleston getaway where artistry meets comfort and privacy. This stay features a main home plus a private carriage home, offering space, style, and a sense of getaway. Ideal for families or groups wanting design-forward...

  • Charleston
  • 8 Bedrooms
  • 4 Bathrooms
  • Sleeps 16
Ready for the Beach & Sunset Views! Padd...

Condo is located on the top floor (end unit) with marsh vistas and is only 1 mile from the Folly Beach Pier, shopping and eateries. There are bicycle lanes in both directions to Folly Beach from the condo. Across the street are kayak and paddleboard...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 4
Historic, newly renovated, 1 block off u...

Upstairs unit of a 2-unit, historical home, originally constructed in 1908. Updated with brand new kitchen and bathrooms and exterior. Original pine floors, staircase and 2 brick fireplaces (non-functioning for potential fire hazard). Home has been...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 6
Guesthouse Charleston: Historic downtown...

Two charming adjoining apartments offering a total of 5 bedrooms, 5 bathrooms, 2 full kitchens, and 2 roomy living rooms, making them ideal for bigger groups or families seeking both space and comfort. Located just one block from King Street in...

  • Charleston
  • 5 Bedrooms
  • 5 Bathrooms
  • Sleeps 14