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Charleston, SC 2+ Bedroom Vacation Rentals

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1048 rentals found
The Inns | HUGE 10 Bedroom with Speakeas...

Summary:Draped in Spanish moss and located within a gorgeous Charleston neighborhood, this freshly modernized huge 10-bedroom, 7-bath getaway blends timeless Southern character with modern luxury. Recently refreshed in September 2025, this historic...

  • Charleston
  • 10 Bedrooms
  • 7 Bathrooms
  • Sleeps 26
Dream Catcher Suite B | Vibrant 3 Bedroo...

Permit Number: 06052The Space: Welcome to your fresh and roomy 3-story apartment with a bright, transitional style interior. Located just off of Spring Street, this refreshed gem offers the ideal blend of comfort and convenience for your stay in...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 7
Desert Oasis | Great Location, 15 Min to...

Located in the handsome Mixson Neighborhood, this cavernous and beautiful townhouse has everything needed for the ideal stay! Located in Park Circle - near countless eateries, sights, shopping, and nightlife.You'll savor:✔ Paradiso Restaurant ...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 6
Charleston Home w/ Porch - 3 Mi to Folly...

Spend plenty of time calming on South Carolina shores when you make this striking 3-bedroom, 2-bath vacation rental the site of your next fun Atlantic hideaway. Located just mins. from the beautiful Folly Beach, this welcoming bungalow guarantees...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 9
Cozy & beautiful home in Charleston mins...

An fantastic and calming hideaway. This property has a minimum of 30 days rental. This home is completely equipped, located in a family friendly neighborhood with the appeal and vibe of Folly Beach. A cavernous 3br, 2 bath home with master suite ...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 6
The Charleston Suite: The Harper Suite

The Harper Suite:>> Prime Location: Ideal escape from busy streets>> Quick walk to drinks, dinner + shopping>> 20 min to 1 of 3 beaches>> Balcony w/ Bistro Set + Porch Swing>> Professionally Turfed Shared Backyard w/Pergola + Grille>> Beds for 6...

  • Charleston
  • 3 Bedrooms
  • 1 Bathrooms
  • Sleeps 6
Casa Bella Suite B | 3 Blocks to King St...

Permit Number: OP2025-06240The Space: ???? Welcome to Casa Bella B - Your Premier Downtown Retreat! ????Feel luxury and comfort at Casa Bella B's newly remodeled second-floor unit, ideally located in the heart of downtown Charleston. With simple...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 6
2 Bedrooms with king beds and private ba...

Exquisitely decorated! very comfortable beds and cavernous rooms. No smoking! No family pets!

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 4
Historic Condo Just Steps to Upper King ...

Summary:Welcome to this striking Charleston property! Featuring three comfortable bedrooms and two well-appointed bathrooms, this home is accentuated with vibrant green details that add a fresh and inviting touch. The open layout promotes natural...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 8
Beach Chic Meets Classic Charleston+Bike...

Nightly or Monthly* availability (* for 1-6 month stays, please message to inquire for options that may not reflect on calendar) . Stylishly refreshed 1950s Charmer offers Indoor/Outdoor Living in highly sought after Riverland Terrace of Charleston...

  • Charleston
  • 2 Bedrooms
  • 1 Bathrooms
  • Sleeps 5
Boutique Home & Resort Pool  ‘The Berm...

Summary:A short walk from King St. 'The Bermuda' is a cavernous private historic property. Rare downtown amenities include the astounding shared Spring Island Collection Pool, right across the street! The property offers an open kitchen & living...

  • Charleston
  • 3 Bedrooms
  • 3 Bathrooms
  • Sleeps 8
Luxury Two Bedroom Residence with Outdoo...

The Pinch Hotel offers completely outfitted guestrooms, luxury amenities from check-in to check-out, and an ambiance of warmth and surprise, The Pinch is a touch of high culture in the Lowcountry. Let us redefine what a luxury, boutique hotel can...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 4
Dog-friendly townhouse close to downtown...

Summary:Maple Leaves - 30 Day RentalThe Space:Treat yourself to a incredible and memorable escapade to Charleston when you book this impressive two-story townhouse! You are within bicycle riding distance of a grocery store, eateries, and shopping...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 6
Overlooking King Street, Steam Shower, +...

King's Court – Historic Charm & Modern Luxury on King StreetWelcome to King's Court, a elegantly refreshed 2-bedroom, 2-bathroom second-floor apartment located directly on Charleston's iconic King Street. With interiors freshly refreshed in Spring...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 8
Luxury Condo 2 miles to the beach! Great...

Luxury Condo located just mins. from the beach! Cavernous 2 bedroom/ 2 bathroom condo with tons of space! Bedroom 1 has a king size bed with a enormous bathroom, jetted tub, walk in closet. Bedroom 2 has a queen and also a twin bed with a full bath...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 4
Blossoms on Cannon | Where Tranquility B...

Permit Number: 06351The Space: ???? High-Class 2-Story Charleston-Style Home for Groups!- 5 Bedrooms / 4 Bathrooms - Ideal for up to 10 people.- Located on Cannon Street with Private Drive and Parking.- Driveway parking for up to 5 cars, making...

  • Charleston
  • 5 Bedrooms
  • 4 Bathrooms
  • Sleeps 10
Home With Private Pool 'The Blue Lagoon'

Summary:Only 2 short blocks to famed King St. Parlor on your private pool deck & let your vacation begin. This petit abode has all you need, in one striking package. Three bedrooms, each with en-suite bath. A light & bright kitchen & living room...

  • Charleston
  • 3 Bedrooms
  • 3 Bathrooms
  • Sleeps 7
Stylish Getaway in Downtown Charleston

Summary:Discover a guest-favorite getaway just steps from the best of Charleston. This modern yet historic home blends chic design, thoughtful amenities, and a walkable location so you can discover the city without sacrificing comfort or appeal...

  • Charleston
  • 2 Bedrooms
  • 1 Bathrooms
  • Sleeps 5