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Charleston, SC 2+ Bedroom Vacation Rentals

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1054 rentals found
Only 2 Blocks to King | The Gemstone (Su...

Permit Number: 06820The Space: Welcome to this charmingly designed 4-bedroom, 4-bath home on Coming Street, offering chic comfort and an unbeatable downtown Charleston location just two blocks from King Street!Ideal for families or groups, this...

  • Charleston
  • 4 Bedrooms
  • 4 Bathrooms
  • Sleeps 10
B1 at Saint Philip Square, One Block to ...

Welcome to Saint Philip Square, an award-winning collection of historic homes spanning nearly one city block of downtown Charleston. The Adams Bennett House at 174 B#1 Saint Philip Street is a 4-bed 4-bath first floor gem that blends modern comfort...

  • Charleston
  • 4 Bedrooms
  • 4 Bathrooms
  • Sleeps 10
Stylish Haven in Historic CHS! | Petunia...

Permit Number: 06090The Space: Welcome to Petunia Suite, your chic 2-bedroom, 2-bath getaway on Rutledge Avenue in the heart of downtown Charleston!This newly refreshed apartment blends a bright open layout with mid-century modern style and bohemian...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 5
The Haven - Off of King St - Sleeps 4!

A handsome upstairs apartment decorated in a comfortable farmhouse chic aesthetic. Filled with tons of natural light and located right off of King St. This handsome apartment is walkable to everything downtown and contains all of the essentials for...

  • Charleston
  • 2 Bedrooms
  • 1 Bathrooms
  • Sleeps 4
Park-View Light-Filled Condo + Elevator ...

The Edison – Light-Filled Condo Overlooking Dereef ParkAppreciate elevated Charleston living at The Edison, a gorgeously designed 2-bedroom, 2.5-bath condo located in the vibrant Cannonborough-Elliotborough neighborhood. Overlooking Dereef Park...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 4
Historical 2bd Home w. Outdoor Space + P...

Summary:Welcome to The Fleetwood, a freshly remodeled, historical home in the heart of Downtown Charleston. Rich with architectural detail, this unique 2BR/2.5BA two-story suite offers a private back porch overlooking a peaceful garden, fountain...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 4
Guesthouse Charleston: SOUTH (82 A & B)

82 A & B is a cavernous two-story home, charmingly located within walking distance of Charleston's best eateries, bars, and attractions. Ideal for sizable groups, the home features two completely equipped kitchens, two living areas, and multiple...

  • Charleston
  • 8 Bedrooms
  • 9 Bathrooms
  • Sleeps 18
The Marquee On King & Historic Market!

Permit Number: 51196The Space: Welcome to The Marquee, a cavernous two-level condo combination located directly on historic King Street and ideal for enormous groups exploring downtown Charleston!With two connected condos spanning the second and...

  • Charleston
  • 6 Bedrooms
  • 4 Bathrooms
  • Sleeps 13
Entire rental unit in Charleston, South ...

A comfortable 2-bedroom, 1-bathroom apartment in Wagener Terrace. Located within walking distance to eateries, this apartment offers both comfort and convenience. A fast walk to Hampton park and just steps to the local Grocery Store. This apartment...

  • Charleston
  • 2 Bedrooms
  • 1 Bathrooms
  • Sleeps 4
Chic downtown condo. Walk to everything!

Luxury Urban Loft with Stunning Park Vistas & Rooftop RetreatStep into modren city living with this roomy 2-bedroom, 2-bathroom loft in an environmentally friendly, LEED Certified complex. This light-filled home features soaring 10-foot ceilings and...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 5
Beautiful home away from home in downtow...

Cavernous apartment with tons of light! Stunning dining room, living room, and completely furnished kitchen. Free WiFi and Amazon Fire stick on each TV.Animals welcomed; humongous yard and dog door and fenced in dog run . Generous front porch with...

  • Charleston
  • 2 Bedrooms
  • 1 Bathrooms
  • Sleeps 4
Fun Family-Friendly Home near Folly with...

Come stay at our Funky, Fun, Folly-Adjacent Home! Our huge, oak-filled property is located in a peaceful, family-friendly residential neighborhood just 2 miles off the beach. Cut your travel time in half whether you are spending your days at Folly...

  • Charleston
  • 4 Bedrooms
  • 2 Bathrooms
  • Sleeps 6
4BR/4BA Historic + Modern - 2 Units - Wa...

Welcome to the Holy City, and the historic southern appeal of the Charleston peninsula. Our Vacation Rental By Owner is located in handsome downtown Charleston and just mins. away from MUSC, the College of Charleston, and King Street’s shopping...

  • Charleston
  • 4 Bedrooms
  • 4 Bathrooms
  • Sleeps 10
Prime Location in Downtown Charleston

Come see this impressive, entirely furnished executive 3bed/2.5 bath townhouse located in the heart of historic Charleston. Ideal for relocating professionals and corporate travelers, this modren residence combines Southern appeal with modern...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 8
Bee St - Downtown w/ Parking - Walk Ever...

Feel the timeless appeal of Charleston’s historic peninsula, the Holy City. Stay just mins. from MUSC, the College of Charleston, and the vibrant shopping, dining, and nightlife of King Street. From this ideally located downtown home, you’ll be...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 5
Charming 4-bedroom home, 10 Minutes to D...

Totally modernized in 2025 -- Stay comfortably in Charleston at this 4-bedroom home. Each bedroom features a king bed, ensuring a pleasant nighttime's sleep for all guests. With amenities like a washing machine, WiFi, and AC, your stay will be both...

  • Charleston
  • 4 Bedrooms
  • 4 Bathrooms
  • Sleeps 8
Charming James Island Retreat - Close to...

Pet Friendly! Feel the appeal of Charleston from our cavernous, light-filled getaway, located in a serene peaceful family friendly lakeside neighborhood on James Island! Just 8 mins. from the historic downtown and 15 mins. from Folly Beach, this...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 4
Blue Magnolia | Perfect for Large Groups

Summary:Discover Blue Magnolia, your chic and cavernous Charleston getaway. This 7BR/4BA home combines classic Southern appeal with modern comfort, making it ideal for families or groups. Unwind on the inviting front porch, soak in the airy...

  • Charleston
  • 7 Bedrooms
  • 4 Bathrooms
  • Sleeps 17