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Charleston, SC 2+ Bedroom Vacation Rentals

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1068 rentals found
The Parthenon Suites | 2 Blocks to King ...

Permit Number: 05086The Space: Savor the comfort and privacy of two gorgeously appointed homes, ideal for huge groups, families, or special gatherings. Located in a relaxing neighborhood, this cavernous getaway offers everything you need for a...

  • Charleston
  • 10 Bedrooms
  • 6 Bathrooms
  • Sleeps 22
Designer Suite in the Heart of Charlesto...

Immerse yourself in Charleston`s vibrant culture from this gorgeous two-bedroom suite, meticulously designed by a professional interior designer. This light-filled haven blends modern comfort with antique appeal, boasting elegant artwork and a...

  • Charleston
  • 2 Bedrooms
  • 1 Bathrooms
  • Sleeps 4
8BR Downtown Luxury Escape Near King

Summary:Ideal for huge groups, this 8BR/8BA Charleston duplex offers two connected units with identical layouts, each with modern kitchens, beautiful living areas, and Intelligent TVs. Savor luxury linens, high-speed WiFi, and two off-street parking...

  • Charleston
  • 8 Bedrooms
  • 8 Bathrooms
  • Sleeps 18
Spacious Modern Home Near Folly Beach

This striking home is centrally located with painless access to Folly Beach and to downtown. The living area is very roomy for comfortably accommodating enormous groups. The first floor contains an open floor plan with luxury vinyl plank floor, a...

  • Charleston
  • 4 Bedrooms
  • 2 Bathrooms
  • Sleeps 8
Charming Charleston Suite |Sleeps 4| His...

Summary:Settle into this inviting suite-style home in Charleston’s Historic District, where comfort meets appeal. Ideal for unwinding after exploring close by eateries, galleries, and iconic architecture. Unwind with luxury linens, reliable WiFi...

  • Charleston
  • 2 Bedrooms
  • 1 Bathrooms
  • Sleeps 4
Newly Restored Historic Home, Close to K...

Welcome to 12 Cannon Street, Units A & B – a charmingly restored four-bedroom, six-bathroom Charleston-style home in the heart of the city. This combined listing is ideal for bigger families and groups seeking modern amenities within walking...

  • Charleston
  • 4 Bedrooms
  • 6 Bathrooms
  • Sleeps 12
Charm of Charleston - 2 Blocks to King S...

Feel the timeless appeal of Charleston’s historic peninsula, the Holy City. Stay just mins. from MUSC, the College of Charleston, and the vibrant shopping, dining, and nightlife of King Street. From this ideally located downtown home, you’ll be...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 8
Cozy 2-Bedroom Cottage on James Island â...

Welcome to The Cottage!Appreciate a comfortable hideaway in this impressive two-bedroom, one-bath bungalow, comfortably sleeping up to five guests. Perfectly designed for short-term stays, the open layout includes a living room, dining area, and...

  • Charleston
  • 2 Bedrooms
  • 1 Bathrooms
  • Sleeps 5
Perfectly centered between Historic Down...

Ideal Charleston Getaway! One level, no stairs. Located on James Island which is located evenly between Downtown Charlestons attractions and eateries or appreciate Folly Beach with its total Island feel with entertainment and eateries. Come home to...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 5
Pentas Home: Historic Secluded Haven

Permit Number: OP2025-06292The Space: ·Tranquil Two-Story Haven: Cozy 2-bedroom, 1.5-bath getaway in historic Charleston, offering privacy and accessibility.·Outdoor dining: Unwind on a serene patio with a cavernous dining table—ideal for dining...

  • Charleston
  • 2 Bedrooms
  • 1 Bathrooms
  • Sleeps 4
3-bedroom home just 15 mins from charmin...

Your comfortable hideaway awaits in Charleston at this gorgeous home. With 3 pretty queen beds spread across 3 bedrooms, this excellent property offers 2 full bathrooms and a remodeled patio for relaxation or family fun. The property is entirely...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 6
Heritage Haven: Steps to Tradition and T...

Permit Number: 06277The Space: "Welcome to 'Heritage Haven,' your broad two-story getaway designed for groups of 6-7 guests. Located on historic Cannon Street, this gorgeous abode ensures convenience during your stay.???? Accessed through its own...

  • Charleston
  • 3 Bedrooms
  • 1 Bathrooms
  • Sleeps 6
Historic, newly renovated, 1 block off u...

Upstairs unit of a 2-unit, historical home, originally constructed in 1908. Updated with brand new kitchen and bathrooms and exterior. Original pine floors, staircase and 2 brick fireplaces (non-functioning for potential fire hazard). Home has been...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 6
The Hideout | Fire Pit, Movie Deck & Fun...

Bold, bright, and made for fun! This retro-chic space is the second unit of a modren home, featuring vibrant décor, arcade games, and two colorful bedrooms. Outside, relax by the fire pit, play yard games, or savor movie nights on the deck with a...

  • Charleston
  • 2 Bedrooms
  • 1 Bathrooms
  • Sleeps 6
Guesthouse Charleston: SOUTH 105 ALL

This combined listing for South 105 A, B, & 105.5 is a great space for sizable groups. Each unit has 4 bedrooms, and 4.5 bathrooms totaling 12 bedrooms, 12 full bathrooms, 3 half bathrooms, 3 full kitchen/living areas. Located on the desired Spring...

  • Charleston
  • 12 Bedrooms
  • 13 Bathrooms
  • Sleeps 28
Vieux Carre: Charm and Convenience!

Permit Number: 05875The Space: Welcome to your own Parisian pied-à-terre in Charleston! ???? Like its namesake drink, the Vieux Carré is a potent yet sweet blend of efficiency and luxury, embracing the city’s European roots. This second-floor...

  • Charleston
  • 2 Bedrooms
  • 1 Bathrooms
  • Sleeps 4
?? of Charleston - Luxurious & Rustic -N...

Summary:Welcome to the heart of Charleston, where this newly constructed home blends rustic elegance with modern comfort just mins. from King Street’s energy. Ideal for those who care about quality, craftsmanship, and staying somewhere fresh, this...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 8
Oak Loft Downtown | Restored Masterpiece

Summary:Welcome to The Oak Loft, an exceptional 4-bedroom, 3-bathroom top floor unit in the heart of Downtown Charleston. With its distinctive design and creative flair, this one-of-a-kind space offers an inspiring getaway! Located just steps from...

  • Charleston
  • 4 Bedrooms
  • 3 Bathrooms
  • Sleeps 8