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Charleston, SC 2+ Bedroom Vacation Rentals

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1050 rentals found
3 Blocks to King Street | 6 BR | Maison ...

Permit Number: 05740The Space: Stay in the heart of Charleston in this delightfully restored 1890s home just steps from King Street, offering six bedrooms and six and a half bathrooms across two private floors, ideal for enormous groups seeking...

  • Charleston
  • 6 Bedrooms
  • 6 Bathrooms
  • Sleeps 13
Palm Key - Cozy Coastal Charm

Please read the entire listing to ensure Palm Key is a good fit. This is a pet friendly, comfortable and cozy home on James Island that is just 5 miles from historic and breathtaking downtown Charleston and only 6 miles to Folly Beach. Spend time in...

  • Charleston
  • 2 Bedrooms
  • 1 Bathrooms
  • Sleeps 4
Hot Tub Oasis • Parking • 1 Block to...

Summary:Welcome to The Palms of Charleston – Suite A!☀️ Cavernous Shared Courtyard + Hot Tub???? 1 Block to King St – Walk to Charleston’s Finest Dining, Shopping & Nightlife???? Private Porch???? Off-Site Parking for 1 Car????️ Cozy...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 6
Ruby's Escapade: Art Hotel Speakeasy Vib...

Think of Ruby as your eccentric auntie; a flapper girl in the roaring twenties, but now, here in the 1960s, she values the peaceful comfortable coastal amenities of an artist’s hideaway. Boutique art hotel meets completely adorned coastal home...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 8
Designer 2BR Historic Condo Near Hampton...

Charming 2-Bedroom Retreat with Modern ComfortsWelcome to your Charleston home away from home. This attractively decorated 2-bedroom, 1-bath historic condo offers bright natural light, thoughtful design, and two private balconies ideal for...

  • Charleston
  • 2 Bedrooms
  • 1 Bathrooms
  • Sleeps 4
*Newly Renovated!* Guesthouse Charleston...

Welcome to your home away from home in the heart of Charleston. This gorgeously refreshed four-bedroom, four-and-a-half-bathroom residence is located on the first floor of a striking two-unit duplex on the highly charming Spring Street just steps...

  • Charleston
  • 4 Bedrooms
  • 4 Bathrooms
  • Sleeps 10
Downtown Charleston – Walk to Dining &...

Summary:This welcoming 3-bedroom, 3-bath apartment offers visitors convenient access to all the city has to offer. Located on the first floor of a historic Charleston site, and set back from the street with off-street parking, the rental overlooks...

  • Charleston
  • 3 Bedrooms
  • 3 Bathrooms
  • Sleeps 6
The Monroe | Penthouse Victorian in DT C...

Summary:This handsome penthouse offers two king bedrooms, two bathrooms, and twin bunk beds in the living area for up to eight guests. Totally outfitted kitchen and striking Victorian details create sophisticated comfort. Unwind with vistas over...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 6
4BR Charleston Single! One Block to King...

Summary:Welcome to your Charleston getaway, a handsomely preserved 4-bedroom Charleston Single home that combines historic appeal, generous proportions, and a premier location just one block from King Street. Ideal for families or groups who want...

  • Charleston
  • 4 Bedrooms
  • 4 Bathrooms
  • Sleeps 12
Charleston | Velvet Accents + Vinyl Coll...

For travelers at heart and explorers by nature, the Collective Premier Two King Bedroom Suite is the biggest in Emeline’s collection, offering a private apartment-style getaway in historic Charleston. Two alluring king bedrooms, a classy living...

  • Charleston
  • 2 Bedrooms
  • 1 Bathrooms
  • Sleeps 6
Charming 2BR Historic Kitchen House Step...

The Sottile-Glover Kitchen House is in the heart of Charleston’s historic district. Painless walking distance to stores and eateries on King Street, City Market, Colonial Lake, CofC, Museums, and Art Galleries. It is also listed on the National...

  • Charleston
  • 2 Bedrooms
  • 1 Bathrooms
  • Sleeps 4
Bridgeside Bungalow | Scenic Bridge View...

Summary:Welcome to Bridgeside Bungalow! ???? This 3BR/2BA home in Charleston’s historic Hampstead Hill blends 1872 appeal with modern comfort, featuring high ceilings, restored heart pine floors, and a calming piazza ????. Savor vistas of the...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 6
Walk to Upper King St! Historic, Loft-St...

WALK TO KING STREET! Located near Charleston's restaurant & nightlife area on upper King Street, this 2-story, loft-style townhome offers guests fast access to phenomenal shopping, eateries & entertainment AND a comfortable getaway within the city...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 4
The Manor 91.5 by Guesthouse Charleston ...

The property located at 91.5 The Manor is a pretty three story new construction home with a main floor living, dining, kitchen, laundry, and half bath. The second floor features two king ensuites with bespoke constructed in desk areas and access to...

  • Charleston
  • 4 Bedrooms
  • 4 Bathrooms
  • Sleeps 8
Charming Waterfront Cottage only 2 miles...

Gorgeously-restored 1920's bungalow with heart-pine floors and tongue-and-grove wood walls and ceilings. This bungalow is a must for a comfortable and calming visit to Charleston, located on a peaceful country lane yet only two miles to Historic...

  • Charleston
  • 3 Bedrooms
  • 3 Bathrooms
  • Sleeps 6
Downtown Family-Friendly Home By Restaur...

Summary:Flora House occupies the top floor of a majestic Historic Charleston residence dating back to 1905. While thoughtfully modernized for modern living, it elegantly preserves the appeal of its origins, featuring original wood floors and classic...

  • Charleston
  • 4 Bedrooms
  • 2 Bathrooms
  • Sleeps 8
Hot Tub • Rooftop • Parking • Walk...

Summary:Welcome to Camellias on Cannon!☀️ Private Rooftop Deck & Courtyard with Hot Tub???? 3 Blocks to King St! Walk to Charleston’s Finest Dining, Shopping & Nightlife???? Ideal for Giant Groups – Families, Weddings, & Work Retreats???...

  • Charleston
  • 8 Bedrooms
  • 7 Bathrooms
  • Sleeps 16
Courtyard Cottage | Casa Zoë

Summary:OP2026-07257Courtyard Cottage pairs historic appeal with Casa Zoë’s signature style. Tucked just off the street, it offers two well-appointed bedrooms, a full bath, and a private brick courtyard made for morning coffee or late-nighttime...

  • Charleston
  • 2 Bedrooms
  • 1 Bathrooms
  • Sleeps 6