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Charleston, SC 2+ Bedroom Vacation Rentals

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1067 rentals found
Location! Minutes to Downtown and Folly ...

Summary:Welcome to our gorgeous 3-bed, 2-bath 1940s home in the heart of the photogenic Riverland Terrace neighborhood! Appreciate the open kitchen living and mid-century modern design of this refreshed bungalow. Riverland Terrace was once an Indigo...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 6
New design & construction, 6 Bed, 6 EnSu...

Welcome to 183 Saint Philip Street, your chic haven in the heart of Charleston! This new construction offers a prime location, placing you steps away from the city's vibrant attractions & best eateries. Each bedroom features 55" Samsung TVs ...

  • Charleston
  • 6 Bedrooms
  • 6 Bathrooms
  • Sleeps 16
The Manor | 8BR Home in Downtown Charles...

Summary:Step into this charmingly preserved Charleston-style home where old-world appeal meets modern comfort. Ideal for couples, families, or modest groups, it offers a welcoming getaway filled with character in a prime location. Located in a...

  • Charleston
  • 8 Bedrooms
  • 4 Bathrooms
  • Sleeps 16
The Eclipse | 2BR Down - Historic Renova...

Summary:Welcome to The Eclipse, a gorgeously remodeled 2-bedroom home that blends historic appeal with modren design touches. Ideal for couples or modest groups who want comfort, style, and peaceful outdoor space, this property offers a main-floor...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 6
NEW Home | Close to DT & Beaches | 4 BR,...

Summary:Welcome to Coastal Comfort, y'all! Unwind in this bright, modern home constructed in 2025 featuring a roomy kitchen, comfortable bedrooms, and a beach-inspired design. Just 10 mins. to downtown Charleston and 15 to Folly Beach! Savor the...

  • Charleston
  • 4 Bedrooms
  • 3 Bathrooms
  • Sleeps 10
Guesthouse Charleston: WEST (62)

At 62 West, you'll feel right at home during your Charleston visit—front porch included! In addition to comfortable beds, this home offers a cavernous open-concept living room and kitchen, ideal for entertaining. The charmingly landscaped outdoor...

  • Charleston
  • 4 Bedrooms
  • 4 Bathrooms
  • Sleeps 12
Guesthouse Charleston: SOUTH 82 B

Apartment with kitchen, 7-min. walk to Medical University of South CarolinaLaundry facilities and BBQ grilles are available at this smoke-complimentary apartment building. The apartment provides a kitchen with a refrigerator, an oven, a stovetop...

  • Charleston
  • 4 Bedrooms
  • 4 Bathrooms
  • Sleeps 10
Relaxing Condo close to EVERYTHING

This Charleston condo features 3 inviting bedrooms - 1 king bed, 1 queen bed, and 1 twin bed. With 3 bathrooms, including a bathtub, guests will feel right at home in this handsome space. AC and heating ensure a comfortable stay year-round. A...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 5
The Palmetto House

Aparthotel with complimentary parking, 8-min. walk to Medical University of South CarolinaLaundry facilities and complimentary self parking are available at this smoke-complimentary aparthotel. Each apartment provides a kitchen with a refrigerator...

  • Charleston
  • 2 Bedrooms
  • 3 Bathrooms
  • Sleeps 4
Charleston Charmer | Historic Abode Near...

Summary:Step into a delightfully preserved Charleston abode in Cannonborough, where appeal and comfort meet. Ideal for those who want historic architecture, peaceful elegance, and the buzz of King Street within walking distance. This home offers...

  • Charleston
  • 2 Bedrooms
  • 1 Bathrooms
  • Sleeps 5
Charm of Charleston - 2 Blocks to King S...

Feel the timeless appeal of Charleston’s historic peninsula, the Holy City. Stay just mins. from MUSC, the College of Charleston, and the vibrant shopping, dining, and nightlife of King Street. From this ideally located downtown home, you’ll be...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 8
Entire Home Rental in Downtown Charlesto...

Summary:Ideal for a huge family! This home is divided into two apartments, A & B, and this listing is for the entire home. This home sleeps 16 guests total. Just three blocks away from upper King Street. Our magnificent cultural city also offers...

  • Charleston
  • 6 Bedrooms
  • 6 Bathrooms
  • Sleeps 16
4 Bedroom - 4 Blocks to King St. with Pa...

Feel the timeless appeal of Charleston’s historic peninsula, the Holy City. Stay just mins. from MUSC, the College of Charleston, and the vibrant shopping, dining, and nightlife of King Street. From this ideally located downtown home, you’ll be...

  • Charleston
  • 4 Bedrooms
  • 2 Bathrooms
  • Sleeps 10
Elegant & Modern Home in Downtown Charle...

Summary:Welcome to your Charleston hideaway, where modern design meets Southern appeal. This extravagant downtown home is designed with comfort and style in mind, offering the ideal getaway for families, friends, or business travelers looking to...

  • Charleston
  • 4 Bedrooms
  • 4 Bathrooms
  • Sleeps 15
The Kitchen House at 68 Broad | Historic...

Permit Number: 05774The Space: Welcome to the comfortable 1,100-square-foot Kitchen House, a ideal getaway for your next hideaway. This gorgeous home offers two cozy bedrooms, each furnished with a Queen bed for a restful stay. Both rooms are...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 4
Dream Weaver | 4 Blocks to King!

Permit Number: 06052The Space: This handsomely remodeled three-story home is divided into two separate apartments and offers a total of 6 bedrooms and 4 full bathrooms, making it an ideal option for huge groups who want space, comfort, and style...

  • Charleston
  • 6 Bedrooms
  • 4 Bathrooms
  • Sleeps 14
Luxury Bungalow Steps Away From Trendy A...

Steps away from fun & trendy Avondale! Cook your own meals in the charming gourmet kitchen or walk to striking eateries, bars, breweries & shopping. The 8 mile Greenway running trail is just across the street. Quick 5 min. Uber ride to Downtown...

  • Charleston
  • 2 Bedrooms
  • 1 Bathrooms
  • Sleeps 6
Private Pool & Historic Home-‘The Wall...

Summary:A short walk to famed King Street, 'The Walled Garden' is an historically protected Charleston home, with private pool! Renovated with modern amenities, experience the appeal of a traditional Charleston home, with sweeping piazzas...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 10