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Charleston, SC 2+ Bedroom Vacation Rentals

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1066 rentals found
30+ Day Stay | Pool • 2 Ensuite BRs â€...

Summary:This cavernous 2-bedroom, 2.5-bath condo on James Island offers the comfort, convenience, and location you need to appreciate everything the Charleston area has to offer.Located in a peaceful residential community, you'll be just mins. from...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 4
Cozy James Island Cottage with Backyard ...

Tucked away on James Island, this comfortable 4-bedroom bungalow is a favorite for families and groups exploring Charleston. Spend the day at Folly Beach or historic downtown, then relax in the fenced backyard around the gas firepit or gather...

  • Charleston
  • 4 Bedrooms
  • 2 Bathrooms
  • Sleeps 8
Chic & Modern Home in the Heart of Charl...

Summary:Downtown Charleston living, elevated. Welcome to The Charlee on Cannon, a thoughtfully designed four-bedroom getaway featuring broad living spaces, a chef's kitchen, and a private rooftop terrace. Constructed from the ground up with comfort...

  • Charleston
  • 4 Bedrooms
  • 4 Bathrooms
  • Sleeps 14
Casa ZoĂ« | Royal House – Charlestonâ€...

Summary:OP2025-06816OP2025-06817The Royal House is Charleston’s ultimate group escape: a dual-unit Casa Zoë mansion that blends grandeur, design, and independence. With 8 bedrooms, 8 baths, and separate living quarters, it offers shared elegance...

  • Charleston
  • 8 Bedrooms
  • 10 Bathrooms
  • Sleeps 16
The Trifecta at 493 - 3 Suites - On King...

Permit Number: 004141The Space: Welcome to 493 Luxury Suites! These handsomely appointed units are found on the second floor of a historic building on King Street (above Sewing Down South, as seen on “Southern Charm”).Step into the building...

  • Charleston
  • 6 Bedrooms
  • 6 Bathrooms
  • Sleeps 18
2BR Spring Street Retreat - B

Feel the timeless appeal of Charleston’s historic peninsula, the Holy City. Stay just mins. from MUSC, the College of Charleston, and the vibrant shopping, dining, and nightlife of King Street. From this ideally located downtown home, you’ll be...

  • Charleston
  • 3 Bedrooms
  • 1 Bathrooms
  • Sleeps 6
Luxury 4bd French Quarter Retreat w. Par...

Summary:Welcome to your freshly refreshed 4BR/3BA luxury getaway in Charleston’s historic French Quarter. Ideal for families and group getaways, this 3,000 sq. ft. home sleeps 14 guests and features soaring ceilings, exposed brick, a chef’s...

  • Charleston
  • 4 Bedrooms
  • 3 Bathrooms
  • Sleeps 14
Downtown Luxury | The Rainbow Cottage

Permit Number: 06814The Space: Strike gold at The Rainbow Cottage, a warm and welcoming two-story getaway designed for comfort, appeal, and an authentic Charleston stay. Ideal for up to four guests, this thoughtfully designed home offers privacy...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 5
Cottage by Folly Beach with water views

Stunning sunsets from the gigantic deck of our James Island home. 2 miles from Folly Beach, this 2 bedroom, 2 full bath home has everything you will need for a comfortable, serene vacation. Plenty of off street parking and 15 min from downtown with...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 4
8BR Downtown Luxury Home w. Pool & Parki...

Summary:Ideal for huge groups, this 8BR/8BA Charleston duplex offers two connected units with identical layouts, each with modern kitchens, chic living areas, and Intelligent TVs. Savor luxury linens, high-speed WiFi, and two off-street parking...

  • Charleston
  • 8 Bedrooms
  • 8 Bathrooms
  • Sleeps 18
Guesthouse Charleston: WEST (64)

Feel elevated Lowcountry living at West 64, a charmingly redesigned 4-bedroom, 4.5-bath Downtown Charleston getaway, tucked within a private courtyard just two blocks from iconic King Street.Ideal for families, friend getaways, wedding guests, and...

  • Charleston
  • 4 Bedrooms
  • 4 Bathrooms
  • Sleeps 10
Newly Renovated 4BR DT, Walkable!

Summary:Welcome to your Charleston escape, a impressive 4-bedroom getaway where timeless craftsmanship meets modern comfort. With gleaming pine floors, intricate moldings, and gorgeous design details throughout, this home offers the ideal blend of...

  • Charleston
  • 4 Bedrooms
  • 5 Bathrooms
  • Sleeps 10
Chucktown Charm- 8 mins to Credit One

3 bedroomsMaster: KingGuest 1: QueenGuest Two: Queenpack and play supplied*Please Note: We operate our homes like a luxury hotel, just check in with a code and leave your towels on the floor when you check out. We take care of it all. Our linens are...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 6
Royal Cottage II –  Light, Art, & Loca...

Summary:OP2025-06817Royal Cottage II is a modern-meets-historic Casa Zoë sanctuary. Designed with soul, light, and intention. Featuring four thoughtfully appointed bedrooms (each with ensuite baths), vaulted ceilings, wood floors, and...

  • Charleston
  • 4 Bedrooms
  • 5 Bathrooms
  • Sleeps 8
Historic Condo Just Steps to Upper King ...

Summary:Welcome to this striking Charleston property! Featuring three comfortable bedrooms and two well-appointed bathrooms, this home is accentuated with vibrant green details that add a fresh and inviting touch. The open layout promotes natural...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 7
Walk to Hampton Park | Downtown CHS Retr...

Summary:Welcome to a cavernous 3-bedroom, 1-bath townhouse getaway! This home offers a prime location in a peaceful neighborhood, ideal for a peaceful stay. The townhouse features central heating and air, ensuring comfort year-round. Appreciate a...

  • Charleston
  • 3 Bedrooms
  • 1 Bathrooms
  • Sleeps 6
Rutledge Ave - Renovated 2 Bed Home - Do...

Feel the timeless appeal of Charleston’s historic peninsula, the Holy City. Stay just mins. from MUSC, the College of Charleston, and the vibrant shopping, dining, and nightlife of King Street. From this ideally located downtown home, you’ll be...

  • Charleston
  • 2 Bedrooms
  • 1 Bathrooms
  • Sleeps 6
The Coral Steps to King and Michelin Res...

Summary:Feel The Coral, a elegantly designed four-story residence located in the heart of downtown Charleston. This 2-bedroom, 2.5-bathroom home offers the ideal blend of historic Charleston appeal and modern city living.The Space:Welcome to The...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 4