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Charleston, SC 2+ Bedroom Vacation Rentals

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1049 rentals found
Casa Zoë | Grand Sparrow House

Summary:OP2025-05862Casa Zoë’s crown jewel, The James Sparrow House, is a sizable Federal-style landmark reimagined for modern gatherings. Entirely redesigned, it blends 19th-century craftsmanship with bold interiors and curated art. With 9...

  • Charleston
  • 9 Bedrooms
  • 7 Bathrooms
  • Sleeps 27
Historical 2bd Home w. Outdoor Space + P...

Summary:Welcome to The Fleetwood, a newly refreshed, historical home in the heart of Downtown Charleston. Rich with architectural detail, this unique 2BR/2.5BA two-story suite offers a private back porch overlooking a relaxing garden, fountain, and...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 4
The Juliette-Entire Luxury Residence

Suitably located in the heart of Downtown Charleston, it is our honor to introduce The Juliette. Prioritizing an opulent aesthetic with comfort in mind, it is here that you'll find the mastery of accommodation at last.The spaceAll-inclusive of the...

  • Charleston
  • 6 Bedrooms
  • 6 Bathrooms
  • Sleeps 19
St Philip St - Downtown - 3 Bedrooms w/ ...

Feel the timeless appeal of Charleston’s historic peninsula, the Holy City. Stay just mins. from MUSC, the College of Charleston, and the vibrant shopping, dining, and nightlife of King Street. From this ideally located downtown home, you’ll be...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 10
Extended Stay in Charleston! 5 Mi to His...

Near Business & Medical Centers | Painless Highway Access | Fenced Yard Headed to Charleston for a long-term visit? This vacation rental is ideal for making the most of your time in the Lowcountry! The 3-bed, 2-bath home has all the essentials...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 6
Renovated House w. Bikes, Outdoor Patio ...

Summary:Feel classic Charleston appeal in this classy 3-bedroom, 2-bath downtown getaway, ideal for groups of up to eight. Walk one block away to King Street's vibrant stores and eateries, or hop on the bicycles we provide and discover the...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 8
Pooch friendly, minutes from everything....

Appreciate calming vistas of the marsh from the patio of this 3bd 3ba Folly Beach Vacation Rental. This property is located on the second floor of the Marsh Winds community just mins. from the ocean and downtown Folly Beach.A home away from home...

  • Charleston
  • 3 Bedrooms
  • 3 Bathrooms
  • Sleeps 8
Newly Renovated 4BR DT, Walkable!

Summary:Welcome to your Charleston escape, a striking 4-bedroom getaway where timeless craftsmanship meets modern comfort. With gleaming pine floors, intricate moldings, and chic design details throughout, this home offers the ideal blend of appeal...

  • Charleston
  • 4 Bedrooms
  • 5 Bathrooms
  • Sleeps 10
Spacious, Large 4bd w. Outdoor Dining, n...

Summary:Feel the ideal fusion of history and modern luxury at this exceptional 4-bedroom, 3-bath residence. Occupying the upper level of a handsomely restored historic Charleston home, offering an elevated getaway in the heart of the city. Located...

  • Charleston
  • 4 Bedrooms
  • 3 Bathrooms
  • Sleeps 9
West Ashley vacation home 11 minutes fro...

In the enchanting West Ashley area, merely a brief 11-min. car ride from the Port of Charleston's Cruise Terminal, this holiday home provides an ideal getaway for your stay in Charleston. As you step inside, you'll be greeted by a completely...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 6
Historic, newly renovated, 1 block off u...

Located in the heart of the historic district. 1 block off of upper King Street. Everything is a convenient walk...to great eateries, museums, music, Marion square, MUSC hospital....Home was originally constructed in 1906 and newly entirely...

  • Charleston
  • 2 Bedrooms
  • 1 Bathrooms
  • Sleeps 4
The Melody | 2BR Retreat, Steps to King ...

Summary:Welcome to your Charleston hideaway where appeal meets convenience in a gorgeously designed 2-bedroom getaway. Ideal for couples or modest groups, The Melody Retreat offers a relaxing, fresh escape with interiors that feel like home and a...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 4
The Gardenia House | Unit A | Sleeps 7

Summary:Welcome to the Gardenia House in the Preserve, a refined luxury suite in downtown Charleston featuring 3 roomy bedrooms and 3 full baths. Designed for flexibility and comfort, this charming suite can be rented separately or combined with the...

  • Charleston
  • 3 Bedrooms
  • 3 Bathrooms
  • Sleeps 7
Stylish West Ashley Retreat Near Downtow...

Step into your Charleston getaway at this modren West Ashley home—ideal for business travelers, executives, or families. Roomy, sun-filled bedrooms, a modern kitchen, and inviting living areas make work and relaxation simple. Appreciate your...

  • Charleston
  • 2 Bedrooms
  • 1 Bathrooms
  • Sleeps 7
101 Mariners Cay! Luxury Living, Communi...

* BR 1: 1 King, BR 2: 1 Queen, BR 3: 2 Twins, Sleeps: 6Welcome to 101 Mariner's Cay! Appreciate a alluring expansive view of the river and marsh from this 3 bedroom, 2 bathroom condo. Try your luck at fishing from the community dock, or go swimming...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 6
The Parthenon Suites | 2 Blocks to King ...

Permit Number: 05086The Space: Two homes. Ten bedrooms. Walk to King Street.This broad Charleston getaway is designed for enormous groups who want space to gather without sacrificing privacy. Tucked on a peaceful street just a 6-min. walk to King...

  • Charleston
  • 10 Bedrooms
  • 6 Bathrooms
  • Sleeps 20
Waterfront Home in Charleston with Kayak...

Escape to a serene waterfront getaway ideally located between downtown Charleston and Folly Beach. This property is a nature-lover's heaven on half an acre of Charleston appeal. Appreciate fishing, crabbing, kayaking, and bird watching from the...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 7
New Build - Steps to King Street

Feel the epitome of modern Charleston living in this striking, brand new, 5-bedroom, 5-bathroom vacation rental apartment, aptly named The Chateau. Located in the heart of downtown Charleston, this opulent abode offers an unbeatable location with...

  • Charleston
  • 5 Bedrooms
  • 5 Bathrooms
  • Sleeps 14