Charleston-SC.com logo

Charleston, SC 2+ Bedroom Vacation Rentals

Filter 2+ Bedroom Charleston Properties by: Company | Oceanfront | Pet-Friendly | or choose different a Area or Bedrooms
No company options available.
Bedrooms:
1049 rentals found
Picture Perfect Charleston Living on Spr...

This isn't just a stay; it's an invitation to the best of Spring Street. Whether you’re grabbing a coffee at Bad Bunnies or exploring the stores of Upper King, everything is within a few mins.' walk. After exploring, getaway to your gated...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 5
Your Rooftop Haven | Sunset Suite Sereni...

Permit Number: 06506The Space: Welcome to your ideal Charleston home base, a cavernous multi level condo designed for comfort and painless gathering while exploring the city with family or friends!Bedrooms & Bathrooms• Three comfortable bedrooms...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 6
Rutledge Ave - Renovated 2 Bed Home - Do...

Feel the timeless appeal of Charleston’s historic peninsula, the Holy City. Stay just mins. from MUSC, the College of Charleston, and the vibrant shopping, dining, and nightlife of King Street. From this ideally located downtown home, you’ll be...

  • Charleston
  • 2 Bedrooms
  • 1 Bathrooms
  • Sleeps 6
Private Renovated 2BR Charleston Townhom...

Minimum Stay: 30 DaysThis newly modernized two-bedroom, two-bath townhome offers a comfortable and private setting for extended stays in Charleston. Located in a peaceful community just mins. from downtown, MUSC, and local beaches, it provides the...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 5
Blissful Escape | Tranquility in Style (...

Permit Number: 06657The Space: Welcome to The Simonton Suite, a cavernous Charleston getaway just off Spring Street and steps from neighborhood favorites like Bramble. Ideal for groups of up to six guests, this inviting condo blends historic appeal...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 6
The Charleston Suites: The Emerson Suite

The Emerson Suite:>> Prime Location: Ideal escape from busy streets>> Quick walk to drinks, dinner + shopping>> 15 min drive to the beach>> Balcony for private dining>> Professionally turfed backyard with pergola + grille>> Beds for 6 guests>...

  • Charleston
  • 3 Bedrooms
  • 1 Bathrooms
  • Sleeps 6
Charleston Charm~B is 4 miles to Downtow...

This beautiful property is only 4 miles from Downtown Charleston! And centrally located to all of Charleston w/15-20 mins to all surrounding areas. 30 Day Minimum Stay. Within walking distance to some of Charleston local's favorite eateries. This...

  • Charleston
  • 2 Bedrooms
  • 1 Bathrooms
  • Sleeps 4
Rare, Historical Estate near Market St w...

Summary:The Jacob Rabb House (circa 1851) sits in the esteemed Ansonborough neighborhood in the heart of the Historic District of Charleston. Walk to the city’s best dining and landmarks, then getaway to this handsome three-story home with a...

  • Charleston
  • 4 Bedrooms
  • 3 Bathrooms
  • Sleeps 8
Charleston Villa | 6bd, Designer Downtow...

Summary:Welcome to your Charleston escape where cavernous living meets classy design. This six bedroom home is ideal for enormous groups or families looking for comfort, modern amenities, and an inviting patio for gathering. You will savor privacy...

  • Charleston
  • 6 Bedrooms
  • 3 Bathrooms
  • Sleeps 16
The Longshoreman | Neighboring The Cedar...

Permit Number: 07279The Space: Welcome to The Longshoreman, an handsome Charleston getaway set within a gorgeously restored 1880s home where historic appeal meets modern comfort for a memorable stay!Bedrooms & Bathrooms• Cozy queen beds with high...

  • Charleston
  • 3 Bedrooms
  • 1 Bathrooms
  • Sleeps 6
2nd Floor Suite 3BR 2BA | Close to Miche...

Summary:Welcome to Blackberry Suite, a striking 3BR 2BA home ideal for families or groups. This 2nd floor suite is thoughtfully styled with soft inviting accents, the space feels fresh and welcoming. Appreciate a entirely equipped kitchen for simple...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 6
Cozy Elliotborough Retreat | The Artist'...

Permit Number: 06605The Space: Savor the best of Charleston from this striking historic midtown home in the vibrant Cannonborough neighborhood, just a short walk from King Street!This roomy first-floor apartment offers about 1,400 square feet of...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 4
Boho Haven in CHS | Southern Shangri-La ...

Permit Number: 06314The Space: Welcome to Southern Shangri-La on Coming, a tropical-inspired urban getaway tucked just off Coming Street in the heart of downtown Charleston!This second-floor apartment offers about 700 square feet of bright...

  • Charleston
  • 2 Bedrooms
  • 1 Bathrooms
  • Sleeps 4
93.5 A&B - New listing! 6 Bedrooms Close...

The property located at 93.5 unit A & B The Manor is a handsome two-story new construction home providing all the amenities of home combined with beautiful furnishings and an spectacular location.Unit A is the first-floor unit with an open concept...

  • Charleston
  • 6 Bedrooms
  • 6 Bathrooms
  • Sleeps 16
Luxury Two Bedroom Residence with Outdoo...

The Pinch Hotel offers entirely outfitted guestrooms, luxury amenities from check-in to check-out, and an ambiance of warmth and surprise, The Pinch is a touch of high culture in the Lowcountry. Let us redefine what a luxury, boutique hotel can be...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 4
Steps to Charleston's Best! | The Lady B...

Permit Number: 06980The Space: Step into The Lady Banks House, a attractively refreshed two-bedroom getaway where historic appeal meets modern comfort in the heart of Charleston!This inviting home blends extravagant design with comfortable gathering...

  • Charleston
  • 2 Bedrooms
  • 3 Bathrooms
  • Sleeps 4
Palm Key - Cozy Coastal Charm

Please read the entire listing to ensure Palm Key is a good fit. This is a pet friendly, comfortable and cozy home on James Island that is just 5 miles from historic and spectacular downtown Charleston and only 6 miles to Folly Beach. Spend time in...

  • Charleston
  • 2 Bedrooms
  • 1 Bathrooms
  • Sleeps 4
4BR/4BA Historic + Modern - 2 Units - Wa...

Welcome to the Holy City, and the historic southern appeal of the Charleston peninsula. Our Vacation Rental By Owner is located in striking downtown Charleston and just mins. away from MUSC, the College of Charleston, and King Street’s shopping...

  • Charleston
  • 4 Bedrooms
  • 4 Bathrooms
  • Sleeps 10