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Charleston, SC 2+ Bedroom Vacation Rentals

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1047 rentals found
Modern Fully Furnished Home For Rent

Renovated West Ashley Retreat | Near Downtown & Folly BeachThis completely furnished, freshly remodeled home is located in a peaceful, well-established West Ashley neighborhood, ideally positioned near all of Charleston’s top attractions. Guests...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 5
Downtown Duplex - Spring St

Feel the timeless appeal of Charleston’s historic peninsula, the Holy City. Stay just mins. from MUSC, the College of Charleston, and the vibrant shopping, dining, and nightlife of King Street. From this ideally located downtown home, you’ll be...

  • Charleston
  • 8 Bedrooms
  • 8 Bathrooms
  • Sleeps 26
Charming 4-bedroom house in beautiful Ch...

Roomy 4BR Home Near Airport, Boeing, Bosch & Downtown CharlestonWelcome to your home away from home in North Charleston! Whether you're visiting for work, relocating to the area, attending an event, or exploring Charleston's rich history and...

  • Charleston
  • 4 Bedrooms
  • 2 Bathrooms
  • Sleeps 8
Landing | Incredible 2BD, Yoga Studio, G...

Luxury meets laid-back coastal stays at Avalon at James Island in Charleston. Our furnished apartments feature full kitchens, quartz countertops, cavernous walk-in closets, and wrap-around balconies with soaring 9-foot ceilings. Appreciate premium...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 4
Historic Charm & Modern Comfort - Perfec...

Welcome to 12 Cannon Street, Unit B – a delightfully restored two-bedroom, three-bathroom home in the heart of Charleston. This second-floor unit blends historic appeal with modern comfort, offering an ideal getaway for families, couples, and...

  • Charleston
  • 2 Bedrooms
  • 3 Bathrooms
  • Sleeps 6
Charming Charleston Home in the Heart of...

Our striking Charleston home is a cozy three bedroom, one bath, home that is located on a peaceful double dead end road in the heart of West Ashley. The home is close to some of West Ashley most revered eateries (Home Team BBQ, Swig and Swine...

  • Charleston
  • 3 Bedrooms
  • 1 Bathrooms
  • Sleeps 6
Dream Charleston Getaway Perfect for Lar...

Welcome to your ultimate group-friendly Charleston getaway—a cavernous, striking, and gorgeously refreshed property located just mins. from the heart of historic downtown. Designed with gatherings in mind, this unique setup features three separate...

  • Charleston
  • 4 Bedrooms
  • 3 Bathrooms
  • Sleeps 8
European Influences in the Heart of Char...

Summary:Ideal for a huge family! Just three blocks away from upper King Street, the epicenter of the city's acclaimed restaurant and nightlife district. Our magnificent city offers galleries, museums, beautiful churches, great shopping, and the...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 8
Chic and Comfy Home - Close to Downtown ...

This striking home is the ideal base for your Charleston hideaway!Our freshly refreshed home is located less than a mile from Avondale's Downtown, less than 3 miles from Downtown Charleston and about 10 miles to Folly Beach.The Avondale neighborhood...

  • Charleston
  • 2 Bedrooms
  • 1 Bathrooms
  • Sleeps 5
19 Bedrooms in CHS | Private Pool! | The...

Permit Number: 06280The Space: Welcome to your ultimate group hideaway. This broad 4-unit, 19-bedroom property, with a *private pool* is thoughtfully designed for sizable groups, corporate retreats, wedding events, or multi-family vacations...

  • Charleston
  • 19 Bedrooms
  • 15 Bathrooms
  • Sleeps 38
Casa Zoë | Grand Federal Sparrow House ...

Summary:OP2026-07255Sparrow House is a stately Federal-style, National Register residence reimagined for modern group stays. This full-home Casa Zoë gem blends historic appeal—porches, millwork, heart pine floors—with bold, gallery-worthy...

  • Charleston
  • 4 Bedrooms
  • 3 Bathrooms
  • Sleeps 13
Townhouse on Colonial Lake, Near the Bat...

Charmingly Charleston is an charmingly located townhouse located across the street from Colonial Lake and Moultrie Park in downtown Charleston's Historic District. It is a ideal spot for visitors who want to really appreciate living in Charleston...

  • Charleston
  • 2 Bedrooms
  • 1 Bathrooms
  • Sleeps 5
The 65|Steps to King Street & Michelin R...

Summary:Welcome to The Sixty Five, a freshly modernized 3-bedroom, 3-bathroom luxury getaway that comfortably sleeps up to 8 guests. Located just two blocks off King Street, it offers painless access to Charleston’s top shopping, dining, and...

  • Charleston
  • 3 Bedrooms
  • 3 Bathrooms
  • Sleeps 8
6C at Saint Philip Square, One Block to ...

Come experience a luxury stay in the heart of Charleston at Saint Philip Square. Our award-winning collection of historic homes spans nearly one city block, The Aiken House, a 4-bed 4-bath second floor gem that blends modern comfort with...

  • Charleston
  • 4 Bedrooms
  • 4 Bathrooms
  • Sleeps 10
1 Block to Historic King St | The Place ...

Permit Number: 06541The Space: Welcome to The Place to Be, a appealing Charleston getaway on Spring Street right in the heart of downtown! With classic Southern character, multiple levels of living, and plenty of space to relax, this historic home...

  • Charleston
  • 3 Bedrooms
  • 3 Bathrooms
  • Sleeps 7
Renovated 2BR Downtown Gem Near King

Summary:Appreciate this freshly modernized 2BR/2BA condo in Charleston’s Cannonborough neighborhood. Just one block from King Street, this central getaway blends historic appeal with modern finishes. Ideal for up to 5 guests, it offers a...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 6
Pet Friendly Spacious 4BR Family Home Ne...

Kick back and relax in this calm, modren home just mins. from some of Charleston's most trendy attractions. This home is a ideal central location as you discover all Charleston has to offer. The home is located on a peaceful street with plenty of...

  • Charleston
  • 4 Bedrooms
  • 2 Bathrooms
  • Sleeps 10
Old School Charm on Spring | Casa Fuego ...

Permit Number: 07107The Space: Welcome to Casa Fuego Suite A, a cavernous and comfortable ground floor condo just off Spring Street, offering a casual and convenient home base for exploring Charleston!Bedrooms & Bathrooms• Two bedrooms located on...

  • Charleston
  • 2 Bedrooms
  • 1 Bathrooms
  • Sleeps 5