Charleston-SC.com logo

Charleston, SC 2+ Bedroom Vacation Rentals

Filter 2+ Bedroom Charleston Properties by: Company | Oceanfront | Pet-Friendly | or choose different a Area or Bedrooms
No company options available.
Bedrooms:
1065 rentals found
Historic Charm & Modern Comfort - Perfec...

Welcome to 12 Cannon Street, Unit B – a attractively restored two-bedroom, three-bathroom home in the heart of Charleston. This second-floor unit blends historic appeal with modern comfort, offering an ideal getaway for families, couples, and...

  • Charleston
  • 2 Bedrooms
  • 3 Bathrooms
  • Sleeps 6
Historic Charleston meets Modern luxury

Savor Downtown Charleston living at 193 Broad Street, Suite A! This two bedroom, two and a half bathroom apartment on one of Charleston's most iconic and bustling streets is just steps to all that Historic Charleston has to offer! The unobstructed...

  • Charleston
  • 2 Bedrooms
  • 3 Bathrooms
  • Sleeps 4
Walk to Hampton Park | Downtown CHS Retr...

Summary:Welcome to a roomy 3-bedroom, 1-bath townhouse getaway! This home offers a prime location in a peaceful neighborhood, ideal for a peaceful stay. The townhouse features central heating and air, ensuring comfort year-round. Savor a completely...

  • Charleston
  • 3 Bedrooms
  • 1 Bathrooms
  • Sleeps 6
Downtown Corporate Condo/Apartment For R...

Excellent location on East Bay Street. Very close to waterfront park, the market, eateries, shopping, historic tours, etc. This is a 3rd story condo, with elevator access, private porch overlooking East Bay Street. 3 Bedrooms that sleep 6 total...

  • Charleston
  • 3 Bedrooms
  • 1 Bathrooms
  • Sleeps 8
The Blackberry Suite | 3 BR 2BA | 2nd Fl...

Summary:Feel Charleston from The Blackberry Suite! This three-bedroom, two-bathroom condo sleeps six and sits a short walk from downtown's stores, dining, and historic sights. A king, a queen, and a private primary suite with its own bath give your...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 6
Newly Renovated 4BR DT, Walkable!

Summary:Welcome to your Charleston escape, a striking 4-bedroom getaway where timeless craftsmanship meets modern comfort. With gleaming pine floors, intricate moldings, and fashonable design details throughout, this home offers the ideal blend of...

  • Charleston
  • 4 Bedrooms
  • 5 Bathrooms
  • Sleeps 10
The Queens Palace | 8 Bedrooms in Charle...

Permit Number: 05553The Space: Welcome to The Queen’s Palace, your private Charleston getaway made up of three gorgeously restored historic homes in the heart of the Cannonborough–Elliotborough neighborhood. With eight bedrooms, eight bathrooms...

  • Charleston
  • 8 Bedrooms
  • 8 Bathrooms
  • Sleeps 16
NY Times Featured Charming Home | Tully ...

Permit Number: 06858The Space: Welcome to Tully Alley, a really unique Charleston getaway where historic appeal meets modern comfort, featured in major publications including The New York Times, and offering an memorable stay in the heart of the...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 6
 JAMES ISLAND RENTAL 30+ DAY. FULLY FURN...

This home is ideal for Travel Nurses, Contracted Professional or Vacationers. AVAILABILITY CHECK CALENDAR- NO SUBLETS Garage parking, take a brief walk to public transit, grocery shopping or great pizza. Just 3 miles from downtown Charleston and 4...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 6
Magnolia House | Historic Charleston Hom...

Summary:Welcome to Magnolia House, a huge 6 bedroom, 3 bathroom two-story Charleston style home that blends timeless character with comfortable, modern touches. Ideal for families or groups seeking space, beauty, and convenience in one place...

  • Charleston
  • 6 Bedrooms
  • 3 Bathrooms
  • Sleeps 19
Perfect location in historic French Quar...

Renovations have been finished…handsomely modern, completely refreshed bathrooms & kitchen! The addition of a 65" mounted TV in living room makes unwinding & watching your favorite shows a calming way to decompress. We provide a complimentary...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 4
Bright 2bd w. Chef's Kitchen, 1 Block to...

Summary:Bright, open-concept spaces invite you to relax and reconnect, while every bedroom features its own private en-suite bath for the ideal blend of comfort and privacy. Your ideal Charleston stay starts here.The Space:Unwind and recharge in...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 4
Tranquil Oasis | Blocks to King! | The H...

Permit Number: OP2025-06422 06423The Space: Welcome to The Hideaway; a gorgeous downtown getaway made up of two private studio apartments on Spring Street, just 3 blocks from King Street in the heart of Elliotborough–Cannonborough!Ideal for...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 4
Renovated 2bd w. Porch, Gym, Parking, ne...

Summary:Tucked along impressive Spring Street, this newly modernized 2-bedroom, 2-bath getaway captures the essence of Charleston appeal. Fresh paint, plush new linens, and handsome touches bring a sense of modern comfort to this timeless home...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 4
Downtown, 2 Beds, Rosemary Suite

Summary:Welcome to the Rosemary Suite C at The Preserve, a beautiful upper-level getaway in a delightfully restored historic home. This 2-bedroom, 2-bath rental offers a private and chic stay while maintaining the home’s rich character. While the...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 4
The Preserve | Rosemary House | Rutledge...

Summary:Welcome to the Rosemary House at The Preserve, a roomy and elegantly appointed residence occupying the top floors of a charmingly preserved historic home. With 8 bedrooms and 8 bathrooms, this broad property offers ample privacy and comfort...

  • Charleston
  • 8 Bedrooms
  • 8 Bathrooms
  • Sleeps 16
Charming family-friendly casita 5 min to...

Arguably the most convenient location in Charleston! This vibrant 1970’s bungalow is just 5 mins. from downtown and 8 miles from Folly Beach. Walking distance to a shopping center with grocery store, eateries, bars, coffee shop, gas station, and...

  • Charleston
  • 3 Bedrooms
  • 1 Bathrooms
  • Sleeps 7
The Charleston Suites: The Emerson Suite

The Emerson Suite:>> Prime Location: Ideal escape from busy streets>> Quick walk to drinks, dinner + shopping>> 15 min drive to the beach>> Balcony for private dining>> Professionally turfed backyard with pergola + grille>> Beds for 6 guests>...

  • Charleston
  • 3 Bedrooms
  • 1 Bathrooms
  • Sleeps 6