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Charleston, SC 2+ Bedroom Vacation Rentals

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1057 rentals found
Island Retreat - Great for Large Groups

Summary:Conveniently located on James Island, 5 miles from Folly Beach and Downtown Charleston, this lush live oak property features 3 separate units that share a roomy backyard. The individual units provide plenty of space for privacy with 1 king...

  • Charleston
  • 5 Bedrooms
  • 3 Bathrooms
  • Sleeps 14
Boho Rosa | Famous Pink House with Pool ...

Summary:Welcome to Boho Rosa, an award-winning, modernized Charleston-style home where vibrant design meets classic Southern appeal. With its memorable pink exterior and professionally decorated bohemian-chic interior, this home offers a really...

  • Charleston
  • 5 Bedrooms
  • 4 Bathrooms
  • Sleeps 14
4BR Charleston Single! One Block to King...

Summary:Welcome to your Charleston getaway, a delightfully preserved 4-bedroom Charleston Single home that combines historic appeal, generous proportions, and a premier location just one block from King Street. Ideal for families or groups who want...

  • Charleston
  • 4 Bedrooms
  • 4 Bathrooms
  • Sleeps 12
4bd House Downtown w. Rooftop Terrace + ...

Summary:Feel Charleston from the Palmetto on Spring, a remodeled 3-floor home in the striking Cannonborough neighborhood. Ideal for groups, this 4-bedroom, 4.5-bath getaway comfortably sleeps 10+ and features a private rooftop terrace and parking...

  • Charleston
  • 4 Bedrooms
  • 4 Bathrooms
  • Sleeps 10
Suite Carolina

Parties are stringently prohibited at all of our properties. Additionally, serving alcohol to minors is not allowed under any circumstances.

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 6
Family Friendly w/ HOT TUB, near DT, Bea...

Summary:This handsomely refreshed home with a new hot tub located in Riverland Terrace neighborhood of James Island is less than 5 miles from Downtown and 9 miles to Folly Beach. Walk to eateries, bars, golf course, waterfront park with playground...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 9
Casa Zoë | Cottage Row – Side-by-Side...

Summary:OP2025-05857OP2025-05858Cottage Row is a rare Charleston find with two entirely separate, next-door Casa Zoë cottages that together create the ideal setup for groups who want to be close but still have their own space. Tucked in the...

  • Charleston
  • 4 Bedrooms
  • 4 Bathrooms
  • Sleeps 10
EAST 44 - Entire Home, Only 1 Block to K...

East 44 is a gorgeously restored historic home located in the vibrant Cannonborough/Elliotborough neighborhood. Just steps away, you'll find local favorites like Chubby Fish and Island Provisions, appealing stores such as The Tiny Tassel and Hermosa...

  • Charleston
  • 4 Bedrooms
  • 4 Bathrooms
  • Sleeps 10
NEW Waterfront Charleston Home! 10 mins ...

Our home located is located waterfront on the marsh of James Island! 10 mins. from Folly Beach or Downtown in each direction! Appreciate your coffee or have a drink on the back deck while watching the local wildlife and tides go in/out. On a clear...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 12
Luxe 7bd, 6ba Retreat, Steps from King

Summary:Stay steps from upper King Street in this refined getaway blending luxury and appeal. Featuring sleek interiors, modern amenities, and vistas of Charleston’s vibrant downtown, it’s ideal for travelers who want shopping, dining, and...

  • Charleston
  • 7 Bedrooms
  • 6 Bathrooms
  • Sleeps 16
James Island Airstream- Between Downtown...

Our freshly refreshed vintage 1976 Airstream Land Yacht is a comfortable Glamper that has everything you'd need for a cozy stay. Located next to our creek, you'll see water fowl galore while sipping your morning coffee in our outdoor seating area...

  • Charleston
  • 2 Bedrooms
  • 1 Bathrooms
  • Sleeps 4
Casa Zoë: Bright Charleston Cottage Nea...

Summary:OP2026-07256OP2026-07257Point of View Cottage is a bright and airy Casa Zoë getaway made from two seamlessly connected spaces - ideal for families, friends, or groups who want to stay together but still appreciate a bit of breathing room...

  • Charleston
  • 5 Bedrooms
  • 4 Bathrooms
  • Sleeps 14
Rooftop • Hot Tub • Parking • 3 Bl...

Summary:✨ Welcome to Camellias on Cannon – Suite B! ????☀️ Private Rooftop Deck???? Courtyard with Hot Tub???? Ideal for Substantial Groups – Families, Wedding Guests, Bachelor(ettes) & Work Retreats???? 3 Blocks to King St! Walk to...

  • Charleston
  • 4 Bedrooms
  • 3 Bathrooms
  • Sleeps 8
Relaxing, boho home, central to many att...

We are new to Vacation Rental By Owner but well established on @irbnb with super host status and many reviews.Kick back and relax in this calm, chic home just mins. from some of Charleston's most trendy attractions. This home is a ideal central...

  • Charleston
  • 4 Bedrooms
  • 2 Bathrooms
  • Sleeps 10
The Gardenia House | Unit B | Sleeps 13

Summary:Welcome to the Gardenia House in the Preserve, a refined luxury suite in downtown Charleston featuring 4 cavernous bedrooms and 4 full baths. Designed for flexibility and comfort, this elegant suite can be rented separately or combined with...

  • Charleston
  • 4 Bedrooms
  • 4 Bathrooms
  • Sleeps 13
Hip Island House — Newly Renovated!

Summary:Renovated in Dec ‘21, this peaceful and peaceful home with a massive yard and palapa is great for families and friends wanting to experience both Charleston's great Downtown area and beachfront — it's ideally located right between the...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 9
Top Floor & Lake Views! Stylish 2BR Down...

Summary:☀️ Stunning Vistas! Welcome to your 2 BR/2BA Charleston home overlooking Colonial Lake.????Prime location steps from King street and downtown’s best dining & shopping.✨Personalized concierge services! On The Coast Property Group can...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 4
The Mary Scott and Daniel Legare House

Permit Number: 06948The Space: Welcome to your Charleston getaway at 11 George Street!This beautiful and cavernous home features 5 handsomely appointed bedrooms and 3 full bathrooms, making it an ideal getaway for families, friends, or bigger groups...

  • Charleston
  • 5 Bedrooms
  • 3 Bathrooms
  • Sleeps 16