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Charleston, SC 2+ Bedroom Vacation Rentals

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1053 rentals found
Downtown Corporate Condo/Apartment For R...

Excellent location on East Bay Street. Very close to waterfront park, the market, eateries, shopping, historic tours, etc. This is a 3rd story condo, with elevator access, private porch overlooking East Bay Street. 3 Bedrooms that sleep 6 total...

  • Charleston
  • 3 Bedrooms
  • 1 Bathrooms
  • Sleeps 8
Historic 2BR Suite Steps to King St

Summary:Discover Charleston from this appealing 2BR/1BA upstairs getaway in a historic duplex, just steps from King Street. Ideal for up to 6 guests, this downtown gem blends modern comfort with classic character, featuring exposed brick, a private...

  • Charleston
  • 2 Bedrooms
  • 1 Bathrooms
  • Sleeps 5
Only 2 Blocks to King! | The Blue Note

Permit Number: OP2025-06608The Space: Live like a local at Blue Note, our bright and welcoming two-story Charleston home designed for comfort, connection, and simple city living. Ideal for groups of up to eight, the home offers three bedrooms, three...

  • Charleston
  • 3 Bedrooms
  • 3 Bathrooms
  • Sleeps 7
The Philip's Suite, newly renovated 3 Be...

Welcome to the Philip's Suite (Unit B) at 183 Saint Philip Street, your newly modernized Charleston haven 1 BLOCK from King Street! This new construction gem places you steps away from the city's vibrant attractions. Each bedroom features Serena ...

  • Charleston
  • 3 Bedrooms
  • 3 Bathrooms
  • Sleeps 8
2 Bedroom 2 bath Upscale Apartment near ...

Welcome to the Queen Residence. Look no further for extravagant accommodations located on the handsome Colonial Lake. Just a few short blocks to King Street and many of our stores and eateries. Delightful garden with a table and chairs for outdoor...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 4
Dianna Browns Place | Historic District

Permit Number: 06411The Space: Welcome to a charmingly restored second floor apartment in the heart of Charleston’s historic French Quarter. Thoughtfully designed and rich in character, this cavernous two bedroom, two bathroom home blends modern...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 4
Courtyard Cottage | Casa Zoë

Summary:OP2026-07257Courtyard Cottage pairs historic appeal with Casa Zoë’s signature style. Tucked just off the street, it offers two well-appointed bedrooms, a full bath, and a private brick courtyard made for morning coffee or late-nighttime...

  • Charleston
  • 2 Bedrooms
  • 1 Bathrooms
  • Sleeps 6
Luxury Two Bedroom Residence at The Pinc...

With completely outfitted guestrooms, luxury amenities from check-in to check-out, and an ambiance of warmth and surprise, The Pinch is a touch of high culture in the Lowcountry. Let us redefine what a luxury, boutique hotel can be.

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 4
Large, Historic 6BR, Designed to Perfect...

Summary:Welcome to Palmetto Hideaway, a striking 6-bedroom designer home in the heart of downtown Charleston. Ideal for enormous families, friend getaways, or anyone who craves style, space, and character, it immerses you in history while offering...

  • Charleston
  • 6 Bedrooms
  • 6 Bathrooms
  • Sleeps 16
The Manor 91.5 by Guesthouse Charleston ...

The property located at 91.5 The Manor is a impressive three story new construction home with a main floor living, dining, kitchen, laundry, and half bath. The second floor features two king ensuites with bespoke constructed in desk areas and access...

  • Charleston
  • 4 Bedrooms
  • 4 Bathrooms
  • Sleeps 8
Oak House Charleston 2BR in downtown. En...

Feel the gorgeous life in downtown Charleston and relax in this bright home in a gorgeous neighborhood with on-site parking for up to two cars and be close to historic Hampton Park and the historical part of downtown. Eateries, bars, the Citadel, a...

  • Charleston
  • 2 Bedrooms
  • 1 Bathrooms
  • Sleeps 6
Downtown Charleston Home - 1 Block to Ki...

Summary:Stay in this 2-story Charleston getaway just one block from King Street. With 3 bedrooms, 2.5 baths, and intelligent TVs in every room, it’s ideal for families or groups. The outdoor seating area invites casual mornings with coffee or...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 7
Ebony & Ivory | Lofted Charm with Firepl...

Summary:This inviting 3-bedroom loft-style home blends the appeal of a historic downtown property with the warmth of a cabin getaway. Curl up on the couch, or step outside to relax under the swaying palm trees, this home has it all! Perfectly...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 6
Downtown Charleston 2BR/2BA Walk to Dini...

Welcome to the Holy City, and the historic southern appeal of the Charleston peninsula. Our AirBnB is located in elegant downtown Charleston and just mins. away from MUSC, the College of Charleston, and King Street’s shopping and nightlife. This...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 6
Blue Magnolia | Perfect for Large Groups

Summary:Discover Blue Magnolia, your classy and roomy Charleston getaway. This 7BR/4BA home combines classic Southern appeal with modern comfort, making it ideal for families or groups. Unwind on the inviting front porch, soak in the airy interiors...

  • Charleston
  • 7 Bedrooms
  • 4 Bathrooms
  • Sleeps 17
The King | Luxury Home w/ Rooftop Patio

Summary:Discover luxury in this completely modernized haven, located just moments from King St. Indulge in classy interiors awash with natural light from wrap-around windows. This Charleston treasure features 4 bedrooms and 3.5 bathrooms with rain...

  • Charleston
  • 4 Bedrooms
  • 3 Bathrooms
  • Sleeps 10
Renovated Penthouse 4BR 4BA - Walk to Ki...

Feel the timeless appeal of Charleston’s historic peninsula, the Holy City. Stay just mins. from MUSC, the College of Charleston, and the vibrant shopping, dining, and nightlife of King Street. From this ideally located downtown home, you’ll be...

  • Charleston
  • 4 Bedrooms
  • 4 Bathrooms
  • Sleeps 12
Great Downtown Charleston Location!

Feel what it means to live like a local in our 2-story Downtown Charleston home. This home is 6 beds / 5.5 baths and would be ideal for huge groups/families of up to 12 people. Located 1 block off King Street, you can walk to eateries, bakeries...

  • Charleston
  • 6 Bedrooms
  • 5 Bathrooms
  • Sleeps 12