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Charleston, SC 2+ Bedroom Vacation Rentals

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1062 rentals found
Charming Charleston Home in the Heart of...

Our impressive Charleston home is a cozy three bedroom, one bath, home that is located on a peaceful double dead end road in the heart of West Ashley. The home is close to some of West Ashley most revered eateries (Home Team BBQ, Swig and Swine...

  • Charleston
  • 3 Bedrooms
  • 1 Bathrooms
  • Sleeps 6
Beautiful Penthouse Condo Just Steps to ...

Summary:Welcome to The Pink Lotus Penthouse, a gorgeous 2-bedroom, 2-bathroom 2nd floor unit that is located in the heart of downtown Charleston. This fashonable and roomy home offers a ideal blend of modern amenities and historic appeal. With its...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 6
Downtown Charleston 2 Bedroom - Newly Fu...

Summary:Feel the appeal of downtown Charleston in this thoughtfully curated two bedroom home. Perfectly located for exploring, our home offers a beautiful getaway with a completely equipped kitchen, comfortable living spaces, and family friendly...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 6
Hidden Gem • Close to Downtown & Beach...

Summary:Welcome to Lowcountry Lookout ???? A relaxing marsh front getaway in the heart of West Ashley! Surrounded by handsome oak trees, you’re just mins. from Charleston’s top attractions, eateries, beaches, and historic sites. Unwind by the...

  • Charleston
  • 4 Bedrooms
  • 2 Bathrooms
  • Sleeps 8
Charming Home w. 4 Beds, Heart of Downto...

Summary:Welcome to The Chapel, your downtown Charleston getaway combining historic appeal, modern amenities, and unbeatable walkability. Ideal for families, groups of friends, or modest gatherings, this 4-bedroom home offers style, comfort, and a...

  • Charleston
  • 4 Bedrooms
  • 4 Bathrooms
  • Sleeps 10
Perfect location in historic French Quar...

Renovations have been finished…handsomely modern, completely refreshed bathrooms & kitchen! The addition of a 65" mounted TV in living room makes unwinding & watching your favorite shows a calming way to decompress. We provide a complimentary...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 4
Luxury Bungalow Steps Away From Trendy A...

Steps away from fun & trendy Avondale! Cook your own meals in the handsome gourmet kitchen or walk to spectacular eateries, bars, breweries & shopping. The 8 mile Greenway running trail is just across the street. Quick 5 min. Uber ride to Downtown...

  • Charleston
  • 2 Bedrooms
  • 1 Bathrooms
  • Sleeps 6
Oak Loft Downtown | Restored Masterpiece

Summary:Welcome to The Oak Loft, an exceptional 4-bedroom, 3-bathroom top floor unit in the heart of Downtown Charleston. With its distinctive design and creative flair, this one-of-a-kind space offers an inspiring getaway! Located just steps from...

  • Charleston
  • 4 Bedrooms
  • 3 Bathrooms
  • Sleeps 8
Casa Zoë | Elegant 3BR Retreat Near Kin...

Summary:OP2026-07256Palmetto Cottage is a signature Casa Zoë stay—effortlessly chic, light-filled, and ideally placed. With three ensuite bedrooms, open living spaces, and a gorgeously appointed kitchen, it’s designed for simple, comfortable...

  • Charleston
  • 3 Bedrooms
  • 3 Bathrooms
  • Sleeps 8
8BR - Beautiful CHS Home | Great for Gro...

Feel the timeless appeal of Charleston’s historic peninsula, the Holy City. Stay just mins. from MUSC, the College of Charleston, and the vibrant shopping, dining, and nightlife of King Street. From this ideally located downtown home, you’ll be...

  • Charleston
  • 9 Bedrooms
  • 4 Bathrooms
  • Sleeps 16
The Jasmine Suite | 3 Bedrooms Steps fro...

Summary:Feel Charleston from The Jasmine Suite! This three-bedroom, two-bathroom condo sleeps six and sits a short walk from downtown's stores, dining, and historic sights. A king and two queen beds give your group plenty of room to settle in...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 6
Gorgeous Townhouse with a Patio near Kin...

**30 Day Minimum Rental**Freshly refreshed, back unit in duplex with 2 bedrooms and 1.5 bathrooms. Updated finishes throughout the home with stainless steel appliances, wood/ tile floors, and washer and dryer in unit. Open living space downstairs...

  • Charleston
  • 2 Bedrooms
  • 1 Bathrooms
  • Sleeps 4
Downtown Charleston - 4BR Luxurious Geta...

Summary:Discover this 4BR/4BA Charleston hideaway, ideally located just off King Street in the Crosstown neighborhood. Each bedroom offers a private en suite, with modern design, Intelligent TVs, and high-speed WiFi throughout. Savor a entirely...

  • Charleston
  • 4 Bedrooms
  • 4 Bathrooms
  • Sleeps 9
Luxury 8BR/6.5BA Downtown w Outdoor Spac...

Summary:Bring everybody together in this cavernous 8BR/6.5BA Charleston home featuring two kitchens, dual living areas, and chic design throughout. Just 4 blocks from King Street, this getaway offers modern amenities with historic appeal, high-speed...

  • Charleston
  • 8 Bedrooms
  • 6 Bathrooms
  • Sleeps 18
Newly Restored Historic Home, Close to K...

Welcome to 12 Cannon Street, Units A & B – a gorgeously restored four-bedroom, six-bathroom Charleston-style home in the heart of the city. This combined listing is ideal for bigger families and groups seeking modern amenities within walking...

  • Charleston
  • 4 Bedrooms
  • 6 Bathrooms
  • Sleeps 12
The Melody | 2BR Retreat, Steps to King ...

Summary:Welcome to your Charleston hideaway where appeal meets convenience in a delightfully designed 2-bedroom getaway. Ideal for couples or modest groups, The Melody Retreat offers a calming, classy escape with interiors that feel like home and a...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 4
Downtown Charleston Home - 1 Block to Ki...

Summary:Welcome to your Charleston hideaway, a designer-refurnished home just one block from King Street that blends style, comfort, and an indoor-outdoor vibe. Ideal for friends or couples who want walkability, thoughtful design, and a backyard...

  • Charleston
  • 4 Bedrooms
  • 2 Bathrooms
  • Sleeps 12
Tradition with a Modern Twist | The Prim...

Permit Number: 06291The Space: This striking second-floor 2-bedroom, 1-bath home is located inside a historic Charleston residence constructed in 1835, blending classic character with modern comfort in the heart of downtown!Inside you’ll find:-One...

  • Charleston
  • 2 Bedrooms
  • 1 Bathrooms
  • Sleeps 4