Charleston-SC.com logo

Charleston, SC 2+ Bedroom Vacation Rentals

Filter 2+ Bedroom Charleston Properties by: Company | Oceanfront | Pet-Friendly | or choose different a Area or Bedrooms
No company options available.
Bedrooms:
1052 rentals found
Stroll to Local Hotspots | Sapphire Suit...

Permit Number: 06699The Space: Welcome to The Sapphire Suite, a warm and welcoming downtown Charleston getaway located on Cannon Street just two blocks from King Street. With space for six to eight guests, this delightfully refreshed home blends...

  • Charleston
  • 3 Bedrooms
  • 3 Bathrooms
  • Sleeps 6
Spacious 3BR in Pet Friendly Walkable Re...

Summary:Bowen VillageThe Space:Welcome to your freshly modernized chic 3-bedroom, 2-bath guest suite located in the heart of the vibrant, walkable village of Bowen! Savor the ideal blend of luxury and convenience, just steps away from an array of...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 6
2 Bedroom House in Charleston's Most Des...

Located South of Broad in one of Charleston's most coveted historic enclaves, 3 King Street is a delightfully restored circa 1904 Charleston single that blends classic appeal with modern comfort. With its ideal setting, thoughtful renovations, and...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 4
12 Min to King St! Cozy 2 BR/2 BA Bungal...

Sizable fenced-in lot located in a peaceful, safe neighborhood 12 mins. from downtown, you will appreciate our bright, pleasant home!Our guests will appreciate all that our home has to offer! We decorated our home with your ultimate relaxation in...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 6
Guesthouse Charleston: WEST (242 B)

West 242 B is a striking standalone home located in the heart of the Cannonborough/Elliotborough neighborhood, just two blocks from historic King Street. This prime downtown Charleston location offers simple access to the best eateries, coffee...

  • Charleston
  • 4 Bedrooms
  • 3 Bathrooms
  • Sleeps 8
Porch & Palmetto | 2 Flats + Patio + Fre...

Summary:Step into this versatile dual-flat home on historic Cannon Street where you can savor both privacy and shared spaces. Ideal for families, friends traveling together, or couples seeking separate retreats, each flat offers its own appeal but...

  • Charleston
  • 2 Bedrooms
  • 3 Bathrooms
  • Sleeps 8
Spacious 4bd House, New Bathrooms, Near ...

Summary:Feel elevated Charleston living at Emerald Square, a freshly constructed private getaway in the heart of downtown. This sophisticated 4-bedroom, 3.5-bath residence pairs timeless Lowcountry style with modern elegance. Designed for gathering...

  • Charleston
  • 4 Bedrooms
  • 3 Bathrooms
  • Sleeps 10
Waterfront Gem in the heart of James Isl...

Summary:Located in the serene environment of James Island, our waterfront property offers a secluded hideaway that feels like a world apart, yet remains connected to everything you need. This freshly constructed two-bedroom, two-bathroom unit...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 5
Charleston | Historic City Retreat | Gym...

Discover a captivating Lowcountry hideaway at Liberty Place Charleston, a Hilton Club, an fresh boutique getaway seamlessly blending historic southern elegance with modern luxury. Located near historic Liberty Square and within a short walk of the...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 6
Classic Charleston Home Steps From King ...

Summary:Gorgeously restored, entirely furnished downtown Charleston home — just one block from the vibrant stores and eateries of King Street. This handsome 3-bedroom, 2.5/3-bath residence blends historic appeal with modern comfort, giving you the...

  • Charleston
  • 3 Bedrooms
  • 3 Bathrooms
  • Sleeps 6
The Cottage at Saint Philip Square, One ...

Welcome to impressive Saint Philip Square, a esteemed collection of 6 historic homes spanning nearly a city block of downtown Charleston. The Cottage at 180 Saint Philip Street is a beautiful 3BD/3BA complimentary standing home with a private fenced...

  • Charleston
  • 3 Bedrooms
  • 3 Bathrooms
  • Sleeps 7
Cozy Home w/ Yard ~ 9 Mi to Dtwn Charles...

Feel the best of the Charleston area with a stay at this striking 4-bedroom, 2-bathroom vacation rental home. Boasting ample natural lighting, a entirely equipped kitchen for preparing home-cooked meals, and a fenced-in yard for your furry friends...

  • Charleston
  • 4 Bedrooms
  • 2 Bathrooms
  • Sleeps 8
Green Cottage – Private Casa Zoë Down...

Summary:OP2026-07535Green Cottage is your own private Charleston hideaway - historic appeal meets Casa Zoë’s modern elegance. Recently redesigned with two bedrooms and two baths, it’s a ideal blend of comfort and design, tucked just steps from...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 5
Serene Charleston Home Near Airport: Pet...

Explore the cozy attractions and historic sites of coastal South Carolina from the comfort of this Charleston vacation rental. This 2-bedroom, 2-bath home with a additional room offers a relaxing setting to relax with the family with a prime...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 6
Cozy Cottage in the center of Charleston...

Freshly refreshed comfortable bungalow at the center of Charleston city. Conveniently located and close to everything. 3 Miles from downtown Charleston, 11 miles from Folly Beach. Whole Foods Market, Harris Teeter supermarket, various eateries and...

  • Charleston
  • 3 Bedrooms
  • 1 Bathrooms
  • Sleeps 6
Pet-Friendly Charleston Home Near Dtwn!

Escape to this impressive 3-bedroom, 2-bath vacation rental in Charleston. Ideally located, this home puts you within reach of Charleston's top attractions. Appreciate a walk through the historic downtown, dine at acclaimed eateries, or discover...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 8
West Ashley vacation home 11 minutes fro...

In the enchanting West Ashley area, merely a brief 11-min. car ride from the Port of Charleston's Cruise Terminal, this holiday home provides an ideal getaway for your stay in Charleston. As you step inside, you'll be greeted by a entirely outfitted...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 6
The Palmetto State Complex- 4 Condo Comp...

The PERFECT vacation rental for Weddings, Extensive Groups and Families looking to travel in complete opulent comfort and privacy! This 4-suite unit is the ONLY property in Charleston that can host your entire event in their own private suites just...

  • Charleston
  • 8 Bedrooms
  • 8 Bathrooms
  • Sleeps 24