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Charleston, SC 2+ Bedroom Vacation Rentals

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1052 rentals found
Walk to Charleston’s Best Dining and E...

One of four residences in this 1870s-era historic modernized property, the 1,500-square-foot "Chestnut Suite" residence offers you a comfortable getaway. Blending the best of old and new, this historic home has been completely refurbished with...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 4
Palmetto Paradise! Overlooking Beautiful...

Appreciate spectacular marsh vistas from this opulent condo. Wildlife infuses your stay with serenity and relaxation as you savor the surrounding 154 acre property of the Preserve at Clam Farm.Folly Beach is just over a mile away; historic downtown...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 8
Little Betty Coastal Retreat~Minutes fro...

Discover coastal comfort at Little Betty Coastal Retreat, a comfortable studio guest home just mins. from Folly Beach! The guest home, with it`s open floor plan, has a king bed and queen sleeper couch and can accommodate up to four guests. Savor...

  • Charleston
  • 2 Bedrooms
  • 1 Bathrooms
  • Sleeps 4
Downtown Luxury | Rutledge Avenue Inn (S...

Permit Number: 06814The Space: This opulent first-floor condo comfortably hosts up to four guests in Charleston’s sought-after Cannonborough-Elliotborough neighborhood on Rutledge Avenue, with painless parking and fast access to downtown...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 4
The Queen on King Street 7 Bedroom Duple...

Feel the timeless appeal of Charleston’s historic peninsula, the Holy City. Stay just mins. from MUSC, the College of Charleston, and the vibrant shopping, dining, and nightlife of King Street. From this ideally located downtown home, you’ll be...

  • Charleston
  • 7 Bedrooms
  • 4 Bathrooms
  • Sleeps 14
2 Bed Great Location - Close to King Str...

Feel the timeless appeal of Charleston’s historic peninsula, the Holy City. Stay just mins. from MUSC, the College of Charleston, and the vibrant shopping, dining, and nightlife of King Street. From this ideally located downtown home, you’ll be...

  • Charleston
  • 2 Bedrooms
  • 1 Bathrooms
  • Sleeps 6
Your Key to Paradise | Southern Shangri-...

Permit Number: 06323The Space: Welcome to Southern Shangri-La on Coming, a tropical-inspired getaway in the heart of Charleston blending casual island vibes with local appeal!Apartment A is a comfortable ground-floor suite offering about 700 square...

  • Charleston
  • 2 Bedrooms
  • 1 Bathrooms
  • Sleeps 4
The Pearl Suite | Chef's Kitchen | Sleep...

Summary:Feel Charleston from The Pearl Suite! This three-bedroom, three-bathroom condo sleeps six and sits a short walk from downtown's stores, dining, and historic sights. At its heart is a chef's kitchen constructed for gathering, whether you're...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 6
Cozy 2BR Carriage in the heart of Downto...

Summary:Welcome to your Charleston home away from home, a comfortable 2-bedroom carriage home made for families who value comfort, convenience, and thoughtful amenities. Whether you’re traveling with little ones or simply want a getaway where you...

  • Charleston
  • 2 Bedrooms
  • 1 Bathrooms
  • Sleeps 5
1 Block to King St | Plunge Pool | Sleep...

Summary:Feel luxury at The Pink Palm, a striking new construction 4-bedroom, 4-bathroom getaway in downtown Charleston finished in APR 2025. Savor roomy living areas, chic baths, and a entirely equipped kitchen. Unwind in the private plunge pool or...

  • Charleston
  • 4 Bedrooms
  • 4 Bathrooms
  • Sleeps 10
Backyard Serenity, Balcony Views | Palme...

Permit Number: 06838The Space: Welcome to Palmetto House, a attractively restored Charleston home where historic appeal meets modern comfort. With four inviting bedrooms and thoughtful gathering spaces throughout, this home is ideal for families or...

  • Charleston
  • 4 Bedrooms
  • 2 Bathrooms
  • Sleeps 9
Historic Boutique Home ‘Tuckertown’

Summary:A short walk from King St. 'The Tuckertown' is a roomy private historic property. The property offers an open kitchen & living area, opening directly to a traditional southern piazza. Plenty of space for guests to relax. Property amenities...

  • Charleston
  • 4 Bedrooms
  • 4 Bathrooms
  • Sleeps 8
Retreat Near the Charleston Greenway | W...

Summary:Roomy and family-friendly getaway ideally located near the Charleston Greenway with relaxing tidal water vistas. This 4-bedroom, 2.5-bath home offers plenty of room for groups of all sizes, featuring three bedrooms with comfortable queen...

  • Charleston
  • 4 Bedrooms
  • 2 Bathrooms
  • Sleeps 9
St. Tropez House | Historic 2-Story w/ C...

Summary:Welcome to St. Tropez House, a charmingly preserved two-story home that exudes appeal, history, and grace. Located in Charleston’s heart, this home is ideal for guests who appreciate classic architectural details, serene outdoor spaces...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 8
Downtown Charleston - Walk to King Stree...

Summary:Welcome to your beautiful downtown Charleston escape on Felix Street, where modern luxury meets historic character. Ideal for groups or families looking for comfort, walkability and a rooftop deck to appreciate city vistas. You will adore...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 9
The OakTree | Bohemian Charm in DT Charl...

Summary:Welcome to your Charleston hideaway, a thoughtfully designed 2-bedroom getaway that blends bohemian appeal with modern comfort. Ideal for couples, friends, or modest groups, this space offers a balance of style and practicality in a location...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 5
Downtown Charleston Home - 1 Block to Ki...

Summary:Welcome to your Charleston hideaway, a designer-refurnished home just one block from King Street that blends style, comfort, and an indoor-outdoor vibe. Ideal for friends or couples who want walkability, thoughtful design, and a backyard...

  • Charleston
  • 4 Bedrooms
  • 2 Bathrooms
  • Sleeps 12
The Mary Scott and Daniel Legare House

Permit Number: 06948The Space: Welcome to your Charleston getaway at 11 George Street!This appealing and cavernous home features 5 gorgeously appointed bedrooms and 3 full bathrooms, making it an ideal getaway for families, friends, or bigger groups...

  • Charleston
  • 5 Bedrooms
  • 3 Bathrooms
  • Sleeps 16