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Charleston, SC 2+ Bedroom Vacation Rentals

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1057 rentals found
State St B by AvantStay | French Quarter...

This space is available for stays of 30 days or longer.Welcome to State St B, a opulent haven located in the heart of Historic Downtown Charleston. This charming apartment, one of two sister residences, features modren appeal and fashonable design...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 4
Stylish 5BR/5BA Downtown Retreat w Pool ...

Summary:Stay in this freshly modernized 5-bedroom, 5-bathroom downtown getaway accommodating up to 12 guests. Featuring open concept living areas, a entirely equipped kitchen, opulent king beds, and off-street parking. Just one block from King...

  • Charleston
  • 5 Bedrooms
  • 5 Bathrooms
  • Sleeps 12
The Queens Palace | 8 Bedrooms in Charle...

Permit Number: 05553The Space: Welcome to The Queen’s Palace, your private Charleston getaway made up of three gorgeously restored historic homes in the heart of the Cannonborough–Elliotborough neighborhood. With eight bedrooms, eight bathrooms...

  • Charleston
  • 8 Bedrooms
  • 8 Bathrooms
  • Sleeps 16
Elegant and Chic Condo in Downtown Histo...

Find an getaway of calm in this third floor, 2 bedroom, 2 bathroom condo. The open living room/ kitchen provides ample seating for 6. Modern style and amenities can be found throughout this new condo. Completed in 2018 this rental offers something...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 6
Palm Key - Cozy Coastal Charm

Please read the entire listing to ensure Palm Key is a good fit. This is a pet friendly, comfortable and cozy home on James Island that is just 5 miles from historic and breathtaking downtown Charleston and only 6 miles to Folly Beach. Spend time in...

  • Charleston
  • 2 Bedrooms
  • 1 Bathrooms
  • Sleeps 4
The Manor | 8BR Home in Downtown Charles...

Summary:Step into this attractively preserved Charleston-style home where old-world appeal meets modern comfort. Ideal for couples, families, or modest groups, it offers a welcoming getaway filled with character in a prime location. Located in a...

  • Charleston
  • 8 Bedrooms
  • 4 Bathrooms
  • Sleeps 16
Historic Downtown Charleston area - 2 be...

This memorable apartment is the ideal home base for your trip to Charleston. Located behind the historic Edmondston / Alston House Museum. Guests will find a serene space with a kitchenette / living room, as well as two bedrooms and two baths...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 4
PRIME + Rare Location, Restored 1800s Mo...

Summary:Stay in the heart of historic Charleston, just steps from Waterfront Park and the iconic Pineapple Fountain. This delightfully restored 1800s building was remodeled in 2026 with modern interiors, original artwork, and thoughtful amenities...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 4
Charleston Charm~A is 4 miles to Downtow...

This striking property is only 4 miles from Downtown Charleston! 30 Day Minimum Stay. And centrally located to all of Charleston w/15-20 mins to all surrounding areas. Within walking distance to some of Charleston local's favorite eateries. This...

  • Charleston
  • 2 Bedrooms
  • 1 Bathrooms
  • Sleeps 4
Only 2 Blocks to King! | The Blue Note

Permit Number: OP2025-06608The Space: Live like a local at Blue Note, our bright and welcoming two-story Charleston home designed for comfort, connection, and simple city living. Ideal for groups of up to eight, the home offers three bedrooms, three...

  • Charleston
  • 3 Bedrooms
  • 3 Bathrooms
  • Sleeps 7
1850 Charleston Single - Historic Distri...

Legal and Licensed rental (OP2026-07095). Cozy 1200sf, 2 bedroom, 1.5 bath, modernized 1850 single located in old historic district in downtown Charleston in the active Cannonborough-Elliotborough neighborhood. Private courtyard with off-street...

  • Charleston
  • 2 Bedrooms
  • 1 Bathrooms
  • Sleeps 4
Autumn Getaway: Sleeps 16+BackPatio | Ne...

Sleeps up to 16! This modern, freshly remodeled home consists of 2 enormous apartments, rentable separately or together. You have a private backyard to relax/dine with a wide umbrella. Wood floors sit beneath exposed beams, w/ stainless steel...

  • Charleston
  • 6 Bedrooms
  • 4 Bathrooms
  • Sleeps 16
Steps to King Street | Sleeps 7 Guests| ...

Summary:Discover comfort and convenience at The Cypress Suite, a appealing three-bedroom, two-bath hideaway ideally located in the heart of downtown Charleston. With room to sleep up to 8 guests, this roomy suite is ideal for families, groups, and...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 7
1 Block to King & CHS Best Coffee and Re...

The Space: Welcome to your historic Charleston getaway, a handsomely restored 1820 residence combining timeless character with modern comfort in the heart of the city!This property offers two private units, one upstairs and one downstairs, each with...

  • Charleston
  • 6 Bedrooms
  • 5 Bathrooms
  • Sleeps 15
Tranquil Oasis | Blocks to King! | The H...

Permit Number: OP2025-06422 06423The Space: Welcome to The Hideaway; a striking downtown getaway made up of two private studio apartments on Spring Street, just 3 blocks from King Street in the heart of Elliotborough–Cannonborough!Ideal for...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 4
The Ashley House~10 minutes to downtown ...

Summary:Managed by Cobble & Key Property Group LLC dba One Sweet StayCoastal-inspired 3BR/1BA home in Avondale, just mins. from downtown Charleston! Bright and cheerful with beachy décor, comfortable furnishings, and a fun vibe. Savor the roomy...

  • Charleston
  • 4 Bedrooms
  • 1 Bathrooms
  • Sleeps 8
Blocks from King | Precious Gem - Suite ...

Permit Number: 05685The Space: Welcome to this charmingly designed 2-bedroom, 2-bath first-floor suite just two blocks from King Street, offering comfort, style, and an unbeatable downtown Charleston location!Ideal for couples, friends, or modest...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 5
8A at Saint Philip Square, One Block to ...

Welcome to striking Saint Philip Square, a collection of 6 historic homes spanning nearly a city block of downtown Charleston. 178 Unit A Saint Philip St. is a striking 2BD/2BA unit blending modern amenities and historic appeal. Just a block from...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 8