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Charleston, SC 2+ Bedroom Vacation Rentals

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1054 rentals found
A newly renovated classic Charleston hom...

This charmingly furnished historic home offers classic Charleston appeal with modern updates thanks to a recent remodel in 2023. Located in the heart of Charleston's vibrant Eastside neighborhood, it features comfortable living areas, a completely...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 6
Downtown Charleston Piedaterre with Priv...

Located on the middle high ground of our historic peninsula city, this unique carriage home features a gated courtyard with a freshly modernized in-ground pool for your exclusive use -- really a rare find in downtown Charleston. There are two...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 4
Guesthouse Charleston: WEST (64)

Feel Luxury in Downtown Charleston with West 64, a freshly redecorated 4 bedroom, 4.5-bathroom home tucked in a private courtyard off Spring Street. This roomy second-floor getaway features four king beds, one queen bed, and en-suite bathrooms for...

  • Charleston
  • 4 Bedrooms
  • 4 Bathrooms
  • Sleeps 12
Retreat Near the Charleston Greenway-Wat...

Cavernous and family-friendly getaway ideally located near the Charleston Greenway with calming tidal water vistas. This 4-bedroom, 2.5-bath home offers plenty of room for groups of all sizes, featuring three bedrooms with comfortable queen beds and...

  • Charleston
  • 4 Bedrooms
  • 3 Bathrooms
  • Sleeps 9
Steps to Bars & Restaurants|Sleeps 6|Dow...

Summary:Welcome to The Lavender Suite!???? Just steps from King Street, this modren 3-bedroom 3-bathroom getaway blends modern comfort with Southern appeal. Located in the heart of downtown Charleston, this lower level unit features exposed brick...

  • Charleston
  • 3 Bedrooms
  • 3 Bathrooms
  • Sleeps 6
Historic 1850s Home in Heart of Downtown...

Everyone loves our 1850's home located in the "Old City Historic District" of downtown Charleston. Its located less than a 10-min. walk to the center of the King Street and walking distance to the College Of Charleston, MUSC / Roper Hospital...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 7
Guesthouse Charleston EAST 42 D

East 42 - D is a handsome second floor two bedroom two bathroom apartment boasting a huge living, dining, and kitchen area. Just off the living area is a work station, the second bathroom, and laundry closet. The primary bedroom features a king bed...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 6
Relaxation and Location - The Lowcountry...

Spectacular, newly refreshed bungalow centrally located between Folly Beach and historic Downtown Charleston. Savor the relaxing serenity while you relax in the huge outdoor space and sip freshly brewed Nespresso or Charleston Tea Plantation tea on...

  • Charleston
  • 2 Bedrooms
  • 1 Bathrooms
  • Sleeps 4
Charleston Charmer - South of Broad

The Place: This Charleston Charmer is located in the coveted South of Broad / Harleston Village location.  Located in the heart of downtown, right across from Colonial Lake, a short walk to King Street, MUSC, Roper Hospital, College of...

  • Charleston
  • 2 Bedrooms
  • 3 Bathrooms
  • Sleeps 4
Dog-friendly townhouse close to downtown...

Summary:Maple Leaves - 30 Day RentalThe Space:Treat yourself to a excellent and memorable escapade to Charleston when you book this impressive two-story townhouse! You are within bicycle riding distance of a grocery store, eateries, and shopping...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 6
Charming Waterfront Cottage only 2 miles...

Gorgeously-restored 1920's bungalow with heart-pine floors and tongue-and-grove wood walls and ceilings. This bungalow is a must for a comfortable and calming visit to Charleston, located on a peaceful country lane yet only two miles to Historic...

  • Charleston
  • 3 Bedrooms
  • 3 Bathrooms
  • Sleeps 6
Bright Boho Historic Home Downtown Charl...

* This unit is on the lower level of a duplex * • Delightfully modernized historic home in downtown Charleston, gorgeously appointed with personal touches and the amenities of home including organic/nontoxic products!• 20-min. walk to...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 4
8 Bedroom - Newly Renovated - Parking & ...

Feel the timeless appeal of Charleston’s historic peninsula, the Holy City. Stay just mins. from MUSC, the College of Charleston, and the vibrant shopping, dining, and nightlife of King Street. From this ideally located downtown home, you’ll be...

  • Charleston
  • 8 Bedrooms
  • 6 Bathrooms
  • Sleeps 16
8B at Saint Philip Square, One Block to ...

Welcome to Saint Philip Square, an award-winning collection of historic homes spanning nearly one city block of downtown Charleston. The Alexander Wilson House at 178 Unit B Saint Philip St. is a 2-bed 2-bath gem blending modern comfort with...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 6
Overlooking King Street, Steam Shower, +...

King's Court – Historic Charm & Modern Luxury on King StreetWelcome to King's Court, a gorgeously refreshed 2-bedroom, 2-bathroom second-floor apartment located directly on Charleston's iconic King Street. With interiors freshly refreshed in...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 8
Lowcountry Charm | 4BR Spring St. Home w...

Welcome to the Holy City, and the historic southern appeal of the Charleston peninsula. Our Vacation Rental By Owner is located in gorgeous downtown Charleston and just mins. away from MUSC, the College of Charleston, and King Street’s shopping...

  • Charleston
  • 4 Bedrooms
  • 3 Bathrooms
  • Sleeps 11
Club Ed Charleston

Club Ed is on James Island 5 mins to Downtown Charleston & 10 mins to Folly Beach. Club Ed sits on a 1/2 acre of mature landscaping that include azaleas, magnolias, camellia s and enormous Oak trees. Savor laying in the sizable hammock, sitting on...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 6
Beautiful Art Villa in Historic Charlest...

Summary:Located in the heart of downtown Charleston & within the culturally & historically diverse neighborhood of Elliotborough. This 1885 home with mid-century modern design is freshly modernized, clean and with tons of natural light has...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 4