Charleston-SC.com logo

Charleston, SC 2+ Bedroom Vacation Rentals

Filter 2+ Bedroom Charleston Properties by: Company | Oceanfront | Pet-Friendly | or choose different a Area or Bedrooms
No company options available.
Bedrooms:
1062 rentals found
Historic Downtown 3-bedroom house in mar...

Make yourself at home in this completely furnished historic Charleston residence with humongous living space, 3 beds and 4 full bathrooms, located in the heart of downtown Charleston - walking distance of King Street’s top eateries, boutique...

  • Charleston
  • 3 Bedrooms
  • 4 Bathrooms
  • Sleeps 6
Landing | Amazing 2BD, Yoga Studio, Game...

Luxury meets laid-back coastal stays at Avalon at James Island in Charleston. Our furnished apartments feature full kitchens, quartz countertops, roomy walk-in closets, and wrap-around balconies with soaring 9-foot ceilings. Appreciate premium...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 4
Retreat on Spring, Unit B

Welcome to your home away from home in striking Charleston. This handsome home is located in the center of the peninsula within walking distance to King and Calhoun street. This is the second floor unit of a duplex and features 2 bedrooms and 1...

  • Charleston
  • 2 Bedrooms
  • 1 Bathrooms
  • Sleeps 5
Chic 4bd Downtown Home w/ Rooftop

Summary:Feel Charleston in style at this opulent 4BR/4BA downtown home known as The Charlee. Ideal for groups, it features modern design, a chic kitchen, king beds, and a private rooftop terrace. Savor luxury amenities, an EV charger, and a prime...

  • Charleston
  • 4 Bedrooms
  • 4 Bathrooms
  • Sleeps 14
Crosstown @ King | Elegant Downtown Stay...

Summary:Savor downtown convenience in this beautiful 3BR, 2BA Charleston home just a block from King Street. Featuring 2 king bedrooms and 1 queen, plus a flexible air bed, it’s ideal for families or groups. Unwind with luxury linens, high-speed...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 7
Island Retreat - Great for Large Groups

Summary:Conveniently located on James Island, 5 miles from Folly Beach and Downtown Charleston, this lush live oak property features 3 separate units that share a cavernous backyard. The individual units provide plenty of space for privacy with 1...

  • Charleston
  • 5 Bedrooms
  • 3 Bathrooms
  • Sleeps 14
4BR New - Close to Folly Beach!

Escape to this elegant 2025-constructed home on James Island, just 10 mins. from Folly Beach and 20 mins. from downtown Charleston. Featuring 4 roomy bedrooms, 3.5 bathrooms, an open-concept layout, entirely equipped kitchen, garage access, ample...

  • Charleston
  • 4 Bedrooms
  • 3 Bathrooms
  • Sleeps 8
Waterfront Escape - Private Pool, Dock, ...

Welcome to your ultimate waterfront escape just mins. from Folly Beach and the appeal of downtown Charleston. This cavernous home offers an memorable setting for family vacations, group getaways, or special events. Appreciate impressive water...

  • Charleston
  • 5 Bedrooms
  • 4 Bathrooms
  • Sleeps 10
Coastal Comfort in Charleston - Family +...

Welcome to Coastal Comfort, your Charleston home away from home! This 3-bedroom, 2-bath getaway offers the ideal blend of relaxation and convenience — located in a peaceful, family-friendly neighborhood just mins. from Avondale, the airport, and...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 6
The Helène House - Spacious 4BD, 4.5BA ...

Summary:Freshly refreshed 4BR/4.5BA home in laid-back Cannonborough/Elliotborough, ideal for families or friends. Lady Helene, Unit B features 4 ensuite bedrooms, open living/dining, a completely equipped kitchen, games room, private porch...

  • Charleston
  • 4 Bedrooms
  • 4 Bathrooms
  • Sleeps 8
Charming Downtown Charleston, Near Hampt...

Summary:Welcome to a roomy 3-bedroom, 1-bath townhouse getaway! This home offers a prime location in a peaceful neighborhood, ideal for a calming stay. The townhouse features central heating and air, ensuring comfort year-round. Savor a completely...

  • Charleston
  • 3 Bedrooms
  • 1 Bathrooms
  • Sleeps 6
The Lord Ashley - Sleeps 8!

Our sun-filled home features an inviting open floor plan that includes two sitting rooms and a sizable dining area with bar that leads into the roomy chef's kitchen. The entirely equipped kitchen is complete with stainless steel appliances including...

  • Charleston
  • 4 Bedrooms
  • 2 Bathrooms
  • Sleeps 8
The Heart of Historic King St | Cooper S...

Permit Number: 004141The Space: Set on the second floor of a historic King Street building-right above Sewing Down South, featured on Southern Charm-this inviting suite combines classic Charleston character with everyday comfort for a memorable...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 6
Magnolia House | Charleston Home, Walk t...

Summary:Welcome to Magnolia House, a gorgeously styled getaway that blends historic character with modern comfort. Ideal for families, friends, or visitors, it offers painless access to King Street while providing tranquility, comfort, and...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 10
Poolside Palmetto Retreat-Charleston 3 B...

Welcome to your ideal Lowcountry hideaway! Located on a peaceful cul-de-sac in North Charleston, this attractively refreshed 3-bedroom, 2.5-bath entire home offers ample sleeping space for families, friend groups, and gatherings—conveniently...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 10
8BR Downtown Luxury Escape Near King

Summary:Ideal for enormous groups, this 8BR/8BA Charleston duplex offers two connected units with identical layouts, each with modern kitchens, classy living areas, and Intelligent TVs. Savor luxury linens, high-speed WiFi, and two off-street...

  • Charleston
  • 8 Bedrooms
  • 8 Bathrooms
  • Sleeps 18
Beautifully furnished Charming single So...

Totally supplied, attractively furnished, appealing historic home in charming South of Broad Location. Brand new renovations! Fabulous two bedroom/one bath home with off street parking. Steps away from the Battery and King street. Great shopping and...

  • Charleston
  • 2 Bedrooms
  • 1 Bathrooms
  • Sleeps 4
Downtown Corporate Condo/Apartment For R...

Excellent location on East Bay Street. Very close to waterfront park, the market, eateries, shopping, historic tours, etc. This is a 3rd story condo, with elevator access, private porch overlooking East Bay Street. 3 Bedrooms that sleep 6 total...

  • Charleston
  • 3 Bedrooms
  • 1 Bathrooms
  • Sleeps 8