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Charleston, SC 2+ Bedroom Vacation Rentals

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1052 rentals found
Hidden Gem • Close to Downtown & Beach...

Summary:Welcome to Lowcountry Lookout ???? A peaceful marsh front getaway in the heart of West Ashley! Surrounded by striking oak trees, you’re just mins. from Charleston’s top attractions, eateries, beaches, and historic sites. Unwind by the...

  • Charleston
  • 4 Bedrooms
  • 2 Bathrooms
  • Sleeps 8
8BR-Spring Street Retreat ~ 2 Full Homes...

Welcome to the Holy City, and the historic southern appeal of the Charleston peninsula. Our Vacation Rental By Owner is located in impressive downtown Charleston and just mins. away from MUSC, the College of Charleston, and King Street’s shopping...

  • Charleston
  • 8 Bedrooms
  • 6 Bathrooms
  • Sleeps 16
Spacious 3BR in Pet Friendly Walkable Re...

Summary:Bowen VillageThe Space:Welcome to your freshly remodeled classy 3-bedroom, 2-bath guest suite located in the heart of the vibrant, walkable village of Bowen! Savor the ideal blend of luxury and convenience, just steps away from an array of...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 6
Walk To King!

Tucked just beyond the main home and set back from the street in the sought-after Cannonborough–Elliotborough neighborhood, The Retreat Downtown offers a calming, private escape while keeping you just steps from the energy of Upper King...

  • Charleston
  • 2 Bedrooms
  • 1 Bathrooms
  • Sleeps 6
Designer Chic 6BR Full Downtown Charlest...

Feel the timeless appeal of Charleston’s historic peninsula, the Holy City. Stay just mins. from MUSC, the College of Charleston, and the vibrant shopping, dining, and nightlife of King Street. From this ideally located downtown home, you’ll be...

  • Charleston
  • 6 Bedrooms
  • 4 Bathrooms
  • Sleeps 14
Dream Charleston Getaway Perfect for Lar...

Welcome to your ultimate group-friendly Charleston getaway—a roomy, beautiful, and elegantly refreshed property located just mins. from the heart of historic downtown. Designed with gatherings in mind, this unique setup features three separate...

  • Charleston
  • 4 Bedrooms
  • 3 Bathrooms
  • Sleeps 8
Charming Charleston Coastal Cottage

Unwind in our roomy and peaceful Coastal Cottage. Centrally located, 20 mins. from beaches, downtown Charleston, 15 mins. to airport & 5 mins. from Daniel Island where there are walking trails, eateries, grocery store, and much more! Guests have...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 7
Fun Furnished Home Between Downtown CHS ...

As you enter this ultra unique home, the vaulted ceilings and beautiful decor give you a Luxxe vibe. While staying in this centrally located home, you’ll only be:10 mins. to downtown10 mins. to Folly Beach The home comes entirely furnished and is...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 6
Walk Score 98 - 1blk to King St. Outdoor...

Summary:Welcome to your Charleston gathering spot, a cavernous 6-bedroom home constructed for sizable groups seeking style, flexibility, and unbeatable walkability. Featuring two high end kitchens, generous living spaces, and just one block from...

  • Charleston
  • 6 Bedrooms
  • 5 Bathrooms
  • Sleeps 16
Downtown Charleston - Close to King Stre...

Summary:Welcome to your Charleston hideaway, a newly refreshed 3-bedroom, 2-bath home just one block from Upper King Street in the Cannonborough-Elliotborough neighborhood. Ideal for groups or families who want modern comfort, chic design, and...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 7
18th Century Charleston | Church St Kitc...

Permit Number: BL6342The Space: Welcome to this private historic Charleston getaway, a charmingly preserved late 18th century home offering rare privacy, timeless character, and an memorable stay in the heart of the city!Bedrooms & Bathrooms• Two...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 4
Charming Cozy Porch! | Globetrotter Suit...

Permit Number: 07177The Space: Welcome to The Globetrotter – Suite D — a bright, second-floor condo just off Spring Street. With 2 bedrooms, 2 ensuite baths, and flexible sleeping for 4–6 guests, this downtown getaway blends comfort, privacy...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 5
Spacious 2bd King Suites w. Full Kitchen

Summary:The Heirloom on Spring is a striking 2-bedroom, 2-bath getaway embodies the essence of historic Charleston living. Bright and airy with high ceilings and timeless character, it features a completely outfitted kitchen ideal for home-cooked...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 4
The Manor 91.5 by Guesthouse Charleston ...

The property located at 91.5 The Manor is a striking three story new construction home with a main floor living, dining, kitchen, laundry, and half bath. The second floor features two king ensuites with bespoke constructed in desk areas and access...

  • Charleston
  • 4 Bedrooms
  • 4 Bathrooms
  • Sleeps 8
St. Tropez House | Historic 2-Story w/ C...

Summary:Welcome to St. Tropez House, a attractively preserved two-story home that exudes appeal, history, and grace. Located in Charleston’s heart, this home is ideal for guests who savor classic architectural details, serene outdoor spaces, and a...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 8
Southern Charm - Elevated home minutes t...

Embark on an memorable beach hideaway at Southern Charm, strategically positioned just moments from Folly Beach and close to downtown Charleston. This two-story, elevated home offers both comfort and convenience, providing painless access to Folly...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 6
Cozy Townhome Near Downtown Charleston

Welcome to this entirely furnished appealing townhouseconveniently located near the major medical centers and all the magnificent downtown amenities!Three bedrooms with Queen size beds and personal closetsHome office with pull out couchTotally...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 7
1850 Charleston Single - Historic Distri...

Legal and Licensed rental (OP2025-07095). Cozy 1200sf, 2 bedroom, 1.5 bath, remodeled 1850 single located in old historic district in downtown Charleston in the active Cannonborough-Elliotborough neighborhood. Private courtyard with off-street...

  • Charleston
  • 2 Bedrooms
  • 1 Bathrooms
  • Sleeps 4