Charleston-SC.com logo

Charleston, SC 2+ Bedroom Vacation Rentals

Filter 2+ Bedroom Charleston Properties by: Company | Oceanfront | Pet-Friendly | or choose different a Area or Bedrooms
No company options available.
Bedrooms:
1059 rentals found
Downtown - Near Historic Cigar Factory w...

Welcome to the Holy City, and the historic southern appeal of the Charleston peninsula. Our vacation rental is located in handsome downtown Charleston and just mins. away from MUSC, the College of Charleston, and King Street’s shopping and...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 8
West 66 B - Freshly Renovated 2 Bedroom,...

Completed & Now accepting bookings! Located on the corner of Spring and Coming Street in Charleston's vibrant Cannonborough-Elliotborough neighborhood, West 66B is a gorgeous ground-floor flat with modern amenities and timeless touches. This...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 4
New Charleston meets Old Charleston!

https://youtu.be/yoy7_cTP81w Video Link to U-tube PageFirst time on the Vacation Rental By Owner market! This gorgeous monthly rental home is located in the French Quarter in a rather residential area called the Exchange, for its proximity to...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 6
Backyard Oasis with Fire Pit

Welcome to our handsomely remodeled home! Ideal for creating memorable memories together. Picture comfortable nights around the fire pit in the cavernous private backyard, fun barbecues with the outdoor grille, and laughter-filled evenings on the...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 6
2-story downtown Charleston house with b...

Summary:Charleston Charmer - 30 Day RentalThe Space:Are you looking for the ideal home away from home for your next escapade with family and friends? Then, look no further than this two-story home located within a mile of all the hot spots in...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 4
11 Bed Compound for Large Groups, Prime ...

Summary:Welcome to The Grandiose Estate, a private getaway in the heart of downtown Charleston, SC. Located within a meticulously restored historic home, this exclusive property features four completely furnished residences, creating the ideal...

  • Charleston
  • 11 Bedrooms
  • 8 Bathrooms
  • Sleeps 24
Boutique Home & Resort Pool 'The Sulliva...

Summary:A short walk from King St. 'The Sullivan' is a cavernous private historic property. Rare downtown amenities include the marvelous shared Spring Island Collection Pool. The property offers an open kitchen & living area, opening directly to...

  • Charleston
  • 4 Bedrooms
  • 4 Bathrooms
  • Sleeps 11
Central King St Condo: Private Balcony, ...

The Space:Welcome to your fresh, sun-drenched Charleston getaway, ideally positioned on the iconic King Street! This 950 sq ft condo comfortably accommodates up to 6 guests, offering a modern, open-concept design and a private balcony where you can...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 6
The Juliette - Historic Luxury Residence

As featured in Vogue.Named as Charleston’s most design-forward Airbnb.Our upstairs flat suitably located in the heart of Downtown Charleston, it is our honor to introduce The Juliette. Prioritizing an opulent aesthetic with comfort in mind, it is...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 8
Private, Cozy 3bd w. Large Living Spaces

Summary:Escape to the heart of Charleston and experience the ideal blend of comfort, convenience, and style at The Ruby. This appealing 3-bedroom, 2-bath ground-floor apartment offers the ideal home base in downtown Charleston, just three blocks...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 7
Lakefront Charleston Charm: With Private...

Summary:Live the Charleston dream on Lake Frances! This striking home blends classic Charleston and Cape Cod styles with a white picket fence and fruit tree-lined yard. Appreciate paddleboarding, fishing, or calming on the broad bi-level piazza with...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 8
2 Bedrooms with king beds and private ba...

Exquisitely decorated! very comfortable beds and roomy rooms. No smoking! No family pets!

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 4
Entire New 3 Story House w/ Private Heat...

Entire New 3 Story House w/ Private Heated Spa/Pool, Roof Top Deck & Elevator. Brand new home in historic Charleston with private jetted heatable spa/pool and rooftop deck. Located just one block from Upper King Street within the...

  • Charleston
  • 4 Bedrooms
  • 5 Bathrooms
  • Sleeps 12
Marsh Views + Outdoor Living • 10 Min ...

Summary:Welcome to Lowcountry Lookout ????Wake up to peaceful marsh vistas and relax in a bright, coastal getaway just mins. from downtown Charleston. Tucked in a peaceful West Ashley neighborhood, this freshly remodeled home is ideal for a calming...

  • Charleston
  • 4 Bedrooms
  • 2 Bathrooms
  • Sleeps 8
The Chapel | Premier 13BR Estate in Down...

Located in the city center, this welcoming vacation home brings all of Charleston within your reach. Upper King Design District is an painless 11-min. walk away, so you can leave your car at the property, which offers onsite parking, or jump in your...

  • Charleston
  • 13 Bedrooms
  • 12 Bathrooms
  • Sleeps 16
Stay Above Riviera Theater | The Marquee...

Permit Number: 51196The Space: Welcome to Marquee Suite A, a roomy second-floor getaway located right on historic King Street and ideal for experiencing the energy of downtown Charleston!This inviting condo blends historic character with modern...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 6
Cozy Island Cottage

Summary:The Cozy Island Cottage is located under the shade of huge live oak trees on James Island. Conveniently located 5 miles from Folly Beach and downtown, you are just mins. from the best Charleston has to offer. This "beachy farmhouse" bungalow...

  • Charleston
  • 2 Bedrooms
  • 1 Bathrooms
  • Sleeps 6
Courtyard Cottage | Casa Zoë

Summary:OP2026-07257Courtyard Cottage pairs historic appeal with Casa Zoë’s signature style. Tucked just off the street, it offers two well-appointed bedrooms, a full bath, and a private brick courtyard made for morning coffee or late-nighttime...

  • Charleston
  • 2 Bedrooms
  • 1 Bathrooms
  • Sleeps 6