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Charleston, SC 2+ Bedroom Vacation Rentals

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1064 rentals found
The Palmetto House

Aparthotel with complimentary parking, 8-min. walk to Medical University of South CarolinaLaundry facilities and complimentary self parking are available at this smoke-complimentary aparthotel. Each apartment provides a kitchen with a refrigerator...

  • Charleston
  • 2 Bedrooms
  • 3 Bathrooms
  • Sleeps 4
Cozy Townhome Near Downtown Charleston

Welcome to this entirely furnished striking townhouseconveniently located near the major medical centers and all the outstanding downtown amenities!Three bedrooms with Queen size beds and personal closetsHome office with pull out couchTotally...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 7
Historic, newly renovated, 1 block off u...

Located in the heart of the historic district. 1 block off of upper King Street. Everything is a convenient walk...to great eateries, museums, music, Marion square, MUSC hospital....Home was originally constructed in 1906 and newly entirely...

  • Charleston
  • 2 Bedrooms
  • 1 Bathrooms
  • Sleeps 4
Thomas Waring House | Sleeps 23 | Multi-...

Summary:Welcome to the Thomas Waring House at The Preserve, a historic and award-winning residence that offers a unique blend of appeal and modern convenience. Comprising 4 separate units, this broad property features a total of 11 bedrooms and 11.5...

  • Charleston
  • 11 Bedrooms
  • 11 Bathrooms
  • Sleeps 23
The Rosemary House | Sleeps 16 | Multi-U...

Summary:Welcome to the Rosemary House at The Preserve, a cavernous and elegantly appointed residence occupying the top floors of a gorgeously preserved historic home. With 8 bedrooms and 8 bathrooms, this broad property offers ample privacy and...

  • Charleston
  • 7 Bedrooms
  • 7 Bathrooms
  • Sleeps 16
The Gardenia House | Sleeps 20 | Multi-U...

Summary:Welcome to the Gardenia House in the Preserve, a distinguished luxury residence located in the heart of downtown Charleston. This handsome property offers two exclusive suites within a roomy layout of 7 bedrooms and 7 full baths, making it...

  • Charleston
  • 7 Bedrooms
  • 7 Bathrooms
  • Sleeps 20
2BR/2BA Downtown Charleston on Spring St...

Welcome to the Holy City, and the historic southern appeal of the Charleston peninsula. Our Vacation Rental By Owner is located in gorgeous downtown Charleston and just mins. away from MUSC, the College of Charleston, and King Street’s shopping...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 6
The Inns | Historic 2bd Suite w. Huge Po...

Summary:Tucked along photogenic Spring Street, this striking 2-bedroom, 1-bath getaway embodies the essence of Charleston living. Step inside to find bright, airy interiors filled with natural light and timeless design details. Step outside to your...

  • Charleston
  • 2 Bedrooms
  • 1 Bathrooms
  • Sleeps 2
New Historic Home by King St w. Parking!

Summary:Award-winning 4BR/3BA historic Charleston getaway just one block from King Street! This private upstairs home, part of the Revival Street Collection, comfortably sleeps 8+. Features a modern kitchen, dedicated workspace, and a striking...

  • Charleston
  • 4 Bedrooms
  • 3 Bathrooms
  • Sleeps 9
Charleston Coastal Cottage

Unwind in our cavernous and peaceful Coastal Cottage. Centrally located, 20 mins. from beaches, downtown Charleston, 15 mins. to airport & 5 mins. from Daniel Island where there are walking trails, eateries, grocery store, and much more! Guests have...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 7
Classic Home - 5? Location - Historic Di...

Summary:Feel Charleston appeal in this 4BR, 3BA home in the heart of the Historic District. With a Walk Score of 98, you’re just blocks from the iconic City Market and steps to King Street’s top stores, eateries, and rooftops. The home features...

  • Charleston
  • 4 Bedrooms
  • 3 Bathrooms
  • Sleeps 8
Beach Chic Meets Classic Charleston+Bike...

Nightly or Monthly* availability (* for 1-6 month stays, please message to inquire for options that may not reflect on calendar) . Stylishly refreshed 1950s Charmer offers Indoor/Outdoor Living in highly sought after Riverland Terrace of Charleston...

  • Charleston
  • 2 Bedrooms
  • 1 Bathrooms
  • Sleeps 5
Perfect for Groups, Directly off King St...

Summary:Welcome to your cavernous Charleston getaway, where modern remodel meets classic appeal. This rare 6-bedroom home is made up of two entirely equipped units rented together, offering the ideal setup for families or groups who want both...

  • Charleston
  • 4 Bedrooms
  • 2 Bathrooms
  • Sleeps 10
Walkable 3 Bedroom Home Near King St wit...

Feel the timeless appeal of Charleston’s historic peninsula, the Holy City. Stay just mins. from MUSC, the College of Charleston, and the vibrant shopping, dining, and nightlife of King Street. From this ideally located downtown home, you’ll be...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 10
Beautiful Art Villa in Historic Charlest...

Summary:Located in the heart of downtown Charleston & within the culturally & historically diverse neighborhood of Elliotborough. This 1885 home with mid-century modern design is freshly refreshed, clean and with tons of natural light has...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 4
The Sweetgrass Suite - Newly Renovated -...

Feel the timeless appeal of Charleston’s historic peninsula, the Holy City. Stay just mins. from MUSC, the College of Charleston, and the vibrant shopping, dining, and nightlife of King Street. From this ideally located downtown home, you’ll be...

  • Charleston
  • 2 Bedrooms
  • 1 Bathrooms
  • Sleeps 4
93.5 A&B - New listing! 6 Bedrooms Close...

The property located at 93.5 unit A & B The Manor is a handsome two-story new construction home providing all the amenities of home combined with modren furnishings and an spectacular location.Unit A is the first-floor unit with an open concept...

  • Charleston
  • 6 Bedrooms
  • 6 Bathrooms
  • Sleeps 16
Blissful Escape: Tranquility in Style (S...

Permit Number: 06657The Space: Your Roomy Haven in the Heart of CharlestonIdeal for groups of 6, 'The Simonton Suite' offers a comfortable getaway with 3 bedrooms - one king and two queens - and 2 full baths. Located beside The Jetty Cafe off Spring...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 6