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Charleston, SC 2+ Bedroom Vacation Rentals

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1049 rentals found
Group Getaway - 6BR/6BA in Heart of Char...

Summary:Feel true Charleston appeal in this modernized historic home offers three separate 3 bedroom/3 bath units housed within the same home for a total of 9 bedrooms (each with its own FULL en-suite bathroom), 3 full kitchens, outdoor porch space...

  • Charleston
  • 6 Bedrooms
  • 6 Bathrooms
  • Sleeps 12
Charming Renovated Retreat for Work + Pl...

Welcome to your freshly remodeled (Spring 2026) getaway in the West Ashley neighborhood of Charleston, ideally located down the road from a boat launch, just 15 mins. from the airport, 20 mins. to historic downtown Charleston, and 40 mins. to top...

  • Charleston
  • 4 Bedrooms
  • 2 Bathrooms
  • Sleeps 8
Beautiful Daniel Island Home PLEASE BOOK...

This Daniel Island home features every amenities a visiting family could ever need. 20 mins. from the beach, and 25 mins. from the city; this home is the ideal place for your next family trip!Space1 king, 2 queen beds. Great view of Charleston's...

  • Charleston
  • 3 Bedrooms
  • 3 Bathrooms
  • Sleeps 8
Quaint stay near Historic Plantation& Ga...

Escape to this impressive apartment in photogenic Charleston. With two comfortable queen beds, guests appreciate a restful nighttime’s sleep in a serene setting. The space features a cozy living area where you can relax after a day of exploring. A...

  • Charleston
  • 2 Bedrooms
  • 1 Bathrooms
  • Sleeps 5
The Blue Angel-In Ground Pool

Welcome to your Charleston-area getaway! This roomy Home is 2,300 square feet of comfortable living space designed for calming, entertaining, and making memories. The home features a bright open layout with vaulted ceilings, modern floor, and...

  • Charleston
  • 5 Bedrooms
  • 3 Bathrooms
  • Sleeps 14
St. Tropez House | Historic 2-Story w/ C...

Summary:Welcome to St. Tropez House, a handsomely preserved two-story home that exudes appeal, history, and grace. Located in Charleston’s heart, this home is ideal for guests who savor classic architectural details, serene outdoor spaces, and a...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 8
Private Backyard With Fire Pit, 15 Min t...

Welcome to this freshly refreshed guesthouse in the heart of West Ashley. While staying in this adorable 850 sqft. home, you`ll fall in appreciate with the freshly redone kitchen featuring a comfortable breakfast nook. You`ll also savor: Deck with...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 4
2BR Historic Charleston Getaway - C

Feel the timeless appeal of Charleston’s historic peninsula, the Holy City. Stay just mins. from MUSC, the College of Charleston, and the vibrant shopping, dining, and nightlife of King Street. From this ideally located downtown home, you’ll be...

  • Charleston
  • 2 Bedrooms
  • 1 Bathrooms
  • Sleeps 4
Southern Ease | 5BR Next to Cannon Green...

Summary:Welcome to Southern Ease, two upstairs units in Charleston that sleep 10, right next to Cannon Green. If the wedding's next door, it doesn't get easier than this: get ready together, walk over for the ceremony, and come back afterward to...

  • Charleston
  • 5 Bedrooms
  • 4 Bathrooms
  • Sleeps 10
3BR Modern Charleston Artist Getaway

Savor a serene hideaway just 10 mins. from the beach and historic downtown Charleston. This entirely refreshed 3BR/3BA home sits in a peaceful neighborhood surrounded by huge oaks and magnolia trees. Inside, unique local art adds appeal to every...

  • Charleston
  • 3 Bedrooms
  • 3 Bathrooms
  • Sleeps 6
Charleston Charmer! 4BR steps from King ...

Summary:Welcome to your Charleston haven, a handsome 4-bedroom home full of character and appeal just steps from King Street. Ideal for families or friends who want historic appeal, generous space, and the effortless convenience of being in the...

  • Charleston
  • 4 Bedrooms
  • 2 Bathrooms
  • Sleeps 12
The Sweetgrass Suite - Newly Renovated -...

Feel the timeless appeal of Charleston’s historic peninsula, the Holy City. Stay just mins. from MUSC, the College of Charleston, and the vibrant shopping, dining, and nightlife of King Street. From this ideally located downtown home, you’ll be...

  • Charleston
  • 2 Bedrooms
  • 1 Bathrooms
  • Sleeps 4
Easy Walk to King Street! | Casa Fuego S...

Permit Number: 06933The Space: Welcome to Casa Fuego – Suite E, a comfortable second-floor condo designed for casual downtown stays. With 2 bedrooms, 1 bathroom, and flexible sleeping space, this bright getaway is ideal for modest groups or...

  • Charleston
  • 2 Bedrooms
  • 1 Bathrooms
  • Sleeps 5
5BR Charleston Oasis w/ Screened Porch f...

Welcome to our 5-bedroom, 2-bathroom bungalow, where a screened porch, fenced backyard, and painless indoor-outdoor flow make group stays feel simple.• Screened porch with dual fans, seating, and outdoor dining• Fenced backyard with fire pit...

  • Charleston
  • 5 Bedrooms
  • 2 Bathrooms
  • Sleeps 12
LOCATION! Stunning Downtown Home Steps t...

Summary:Welcome to The Pink Lotus, a appealing 4-bedroom, 4-bathroom duplex located in the heart of downtown Charleston. This charming and roomy home offers a ideal blend of modern amenities and historic appeal. With its prime location, you'll have...

  • Charleston
  • 4 Bedrooms
  • 4 Bathrooms
  • Sleeps 12
Your Rooftop Haven | Sunset Suite Sereni...

Permit Number: 07443The Space: Welcome to your ideal Charleston home base, a roomy multi level condo designed for comfort and simple gathering while exploring the city with family or friends!Bedrooms & Bathrooms• Three comfortable bedrooms across...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 6
French Quarter Escape – Walk to City M...

Maison Des Fleurs – Sophisticated Pied-à-Terre in Charleston's French QuarterTucked along beautiful Lodge Alley in the heart of Charleston's historic French Quarter, Maison Des Fleurs is a attractively modernized 2-bedroom, 1.5-bathroom getaway...

  • Charleston
  • 2 Bedrooms
  • 1 Bathrooms
  • Sleeps 4
Palm House | Furnished 5BR MTR in Charle...

Summary:Furnished whole-home rental in West Ashley for stays of 30 nights or more, available February 1 2027. All five bedrooms and three bathrooms are open to guests, including the primary suite with its en suite bathroom. Fenced yard, two...

  • Charleston
  • 5 Bedrooms
  • 3 Bathrooms
  • Sleeps 8