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2+ Bedroom Vacation Rentals

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1419 rentals found
Charming Beach Cottage with Lagoon views...

Charming Beach Cottage. Designer Furnished with rich hard wood floors. Extensive Kitchen with Screened Porch overlooking the Pelican Bay Lagoon. Soaring Vaulted Ceilings in Living Room. Ample parking for 4 cars. Enormous LCD TVs in Living Room and...

  • Isle of Palms
  • 3 Bedrooms
  • 3 Bathrooms
  • Sleeps 8
Historic Duplex 6 Blocks To King - Lots ...

Summary:Take it simple on the porch after a long day at the beach, then pull up a chair for a casual dinner. This charming duplex offers a touch of sophistication tucked into historic downtown Charleston.Think of everything you'd want for your ideal...

  • Charleston
  • 6 Bedrooms
  • 4 Bathrooms
  • Sleeps 12
Cozy tropical oasis 10 minutes from beac...

We have it all! Have fun with family, friends & Fido @ this comfortable tropical getaway. Located between Folly beach & downtown Charleston. Entire residence w/privacy fence, fire pit, grilles (propane & green egg), outdoor dining area, hammock...

  • Charleston
  • 3 Bedrooms
  • 1 Bathrooms
  • Sleeps 6
Beautiful Art Villa in Historic Charlest...

Summary:Set on the upper floor of a charmingly modernized 1885 Charleston single, this 2-bedroom suite feels like living in the city, not just visiting it. The space is bright and open with a mid-century modern feel, two queen bedrooms, two private...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 4
Luxury Boutique Hotel Vibes. More Space,...

Feel boutique luxury in the heart of downtown Charleston. At Concept House, every detail is curated—from locally sourced furnishings to serene, beautiful spaces that invite you to relax. Wake up in crisp linens, sip coffee in the private manicured...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 5
Charming 3-BR Historic Charleston home n...

Feel the timeless appeal of Charleston’s historic peninsula, the Holy City. Stay just mins. from MUSC, the College of Charleston, and the vibrant shopping, dining, and nightlife of King Street. From this ideally located downtown home, you’ll be...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 6
Beautiful Townhome 10 min from Charlesto...

This charming 3 Bedroom, 2.5 Bathroom Townhome is elegant from top-to-bottom! Located in Mount Pleasant, SC, this home is located in a thriving area with tons of great places to see. It is just mins. from downtown, and two local resort island...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 6
Updated 3 bedroom house minutes from Cha...

This location has it ALL! Family friendly in a peaceful neighborhood ideally located to savor all the area has to offer. Short drives to Folly Beach the most laid back beach with the best waves for surfing/body boarding, historic downtown...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 8
Fit & Coasty - 2bd w/ Firepit, Workspace...

Welcome to Fit & Coasty in striking West Ashley! Our home is ideal for any size group or those traveling for work for 30+ days! Our home is entirely equipped with everything you need for a comfortable stay, including a completely supplied kitchen...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 4
Palm Key - Cozy Coastal Charm

Please read the entire listing to ensure Palm Key is a good fit. This is a pet friendly, comfortable and cozy home on James Island that is just 5 miles from historic and spectacular downtown Charleston and only 6 miles to Folly Beach. Spend time in...

  • Charleston
  • 2 Bedrooms
  • 1 Bathrooms
  • Sleeps 4
Casa Zoë | Elegant 3BR Retreat Near Kin...

Summary:OP2026-07256Palmetto Cottage is a signature Casa Zoë stay—effortlessly fresh, light-filled, and ideally placed. With three ensuite bedrooms, open living spaces, and a charmingly appointed kitchen, it’s designed for simple, comfortable...

  • Charleston
  • 3 Bedrooms
  • 3 Bathrooms
  • Sleeps 8
Water views & only 2 miles to downtown

Charming home along the Ashley River, has striking marsh & river vistas located on a private 1-acre lot lined with 300 year old live oaks & only 2 miles from downtown Charleston. Savor the modern touches of 2 delightfully refreshed bathrooms ...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 6
Moultrie & Palmetto Suites | Walk to Bar...

Summary:Welcome to The Moultrie & Palmetto, a chic 6 bedroom, 4 bathroom property spanning two units in the same downtown Charleston building. Sleeps a enormous group together while giving everybody their own space to land. Step outside and King...

  • Charleston
  • 6 Bedrooms
  • 4 Bathrooms
  • Sleeps 14
CLASSIC and Cozy IOP Beach Home, Family-...

Great Family Friendly 5 bedroom home located on a corner lot. Only two blocks from the IOP marina and close to the beach. This home is boat friendly with simple access to the IOP Boat Ramp. You will adore how this home can accommodate a very huge...

  • Isle of Palms
  • 5 Bedrooms
  • 3 Bathrooms
  • Sleeps 12
314 C Shipwatch by AvantStay | OCEANFRON...

_Note: The Shipwatch complex will be undergoing renovations from November 12, 2026 through February 2027. Each building is expected to be impacted for roughly 6–8 weeks during the project. While the condos will remain accessible, the work is...

  • Isle of Palms
  • 3 Bedrooms
  • 3 Bathrooms
  • Sleeps 8
Tropicana Cabana with Fenced Yard

Tropicana CabanaLocation: Isle of Palms, South CarolinaOverview:Welcome to Tropicana Cabana, a appealing 3-bedroom, 2-bathroom beach home on the Isle of Palms. Ideal for families (including well-behaved furry friends), this inviting home offers a...

  • Isle of Palms
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 8
Downtown Historic Home Steps to King St

Summary:Welcome to this beautiful Southern bungalow, where classic elegance meets modern comfort. This enchanting home features four cavernous bedrooms and two handsomely appointed bathrooms, ideal for family living or entertaining guests. The...

  • Charleston
  • 4 Bedrooms
  • 2 Bathrooms
  • Sleeps 13
712 Ocean Blvd | New Build + Pool, Game ...

Sun, sand, and wellness collide at Stay Salty—a brand-new, oceanfront getaway on Isle of Palms where modern luxury meets intentional, healthy living. With six bedrooms (including 5 California King beds), six full bathrooms, and a powder room, this...

  • Isle of Palms
  • 6 Bedrooms
  • 7 Bathrooms
  • Sleeps 12