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Charleston, SC 2+ Bedroom Vacation Rentals

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1144 rentals found
*Newly Renovated!* Guesthouse Charleston...
4.6
(13)

Close to ecotours, birdwatching, and more, this smoke-complimentary vacation home brings it all within reach. There's convenient onsite parking, so you can leave your car behind and let your feet make short work of the 8-min. walk to Upper King...

  • Charleston
  • 4 Bedrooms
  • 4 Bathrooms
  • Sleeps 10
Cozy Townhouse in heart of West Ashley
5.0
(34)

This freshly remodeled townhouse is located in the heart of West Ashley amidst a nice peaceful neighborhood.As you enter you will find a living room with a beautiful fireplace, intelligent TV, and a comfortable couch. A full kitchen, washer/dryer...

  • Charleston
  • 2 Bedrooms
  • 1 Bathrooms
  • Sleeps 4
Austele Suite | Prime Location, Walk to ...
4.8
(26)

Summary:Discover a cheerful downtown getaway that blends convenience, comfort and appeal. This thoughtfully designed studio is ideal for solo travelers, couples or business guests who want modern ease while staying steps away from Charleston’s...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 5
North Central, 30-Day Rental Home w/Doub...

1 Francis - 30 Day RentalOur calendar is refreshed in real-time & our nightly prices are accurately displayed. Simply enter your desired dates and click 'Book Now!'An ideal, appealing space for a summer vacation, a winter escape, or short-term...

  • Charleston
  • 2 Bedrooms
  • 1 Bathrooms
  • Sleeps 4
The Monroe | Penthouse Victorian in DT C...
5.0
(4)

Summary:This handsome penthouse offers two king bedrooms, two bathrooms, and twin bunk beds in the living area for up to eight guests. Entirely outfitted kitchen and striking Victorian details create sophisticated comfort. Unwind with vistas over...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 6
Downtown Duplex - St Philip St - Sleeps ...
5.0
(2)

Feel the timeless appeal of Charleston’s historic peninsula, the Holy City. Stay just mins. from MUSC, the College of Charleston, and the vibrant shopping, dining, and nightlife of King Street. From this ideally located downtown home, you’ll be...

  • Charleston
  • 6 Bedrooms
  • 5 Bathrooms
  • Sleeps 16
Great Stay in Charleston, SC. Easy walk ...

This newly modernized upstairs condo has been decorated for your ease and comfort. All beds are deluxe pillow-top and the couch is soft, big,very deep, and comfortable. The living room has a 52" intelligent TV and high speed internet is included. ...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 5
Condo on King Street - Rooftop & Terrace...

Summary:Welcome to this modern King Street condo constructed for comfort, style, and family stays. Ideal for couples or modest groups wanting a blend of convenience and ease, you’ll appreciate rooftop access with vistas, a calming bathtub, and...

  • Charleston
  • 2 Bedrooms
  • 1 Bathrooms
  • Sleeps 5
Modern Elegance in North Charleston!

Step inside a thoughtfully designed space featuring modern décor, sleek finishes, and comfortable touches that make it feel like home. This inviting hideaway includes:✔ Cavernous Living Area – Unwind in an open-concept living room with a plush...

  • Charleston
  • 3 Bedrooms
  • 3 Bathrooms
  • Sleeps 8
Quaint Townhome in the Heart of Charlest...

The resort is an Historic 18th century warehouse that has been lovingly restored to preserve the history while also providing guests with all the modern-day amenities and amenities. Savor an afternoon cap of sherry and some fresh baked cookies after...

  • Charleston
  • 2 Bedrooms
  • 1 Bathrooms
  • Sleeps 6
Six on Cannon | 6BR Charleston Home + Pa...
3.4
(5)

Summary:Welcome to Six on Cannon, a roomy 6 bedroom 2 bathroom home ideally suited for families, friends, or get-togethers who want room, style, and downtown convenience together. Freshly furnished and thoughtfully arranged, it gives you all the...

  • Charleston
  • 6 Bedrooms
  • 2 Bathrooms
  • Sleeps 16
Live like a local in Historic Charleston...
5.0
(20)

Spectacular Historic District condo. Walking distance to all that Charleston has to offer. King Street Shopping, fine dining, Spoleto, College of Charleston, or strolling through historic Charleston. All a short walk away. Two bedrooms, two...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 4
1 Block to King St | Plunge Pool | Sleep...

Summary:Feel luxury at The Pink Palm, a impressive new construction 4-bedroom, 4-bathroom getaway in downtown Charleston finished in APR 2025. Appreciate cavernous living areas, fashonable baths, and a entirely equipped kitchen. Unwind in the...

  • Charleston
  • 4 Bedrooms
  • 4 Bathrooms
  • Sleeps 10
On Folly Time | Beach Oasis with Water V...

Summary:Wake up to gentle waves and salty breezes in this dreamy beachfront getaway. On Folly Time offers impressive water vistas, direct beach access, and calming surroundings. Ideal for couples, modest families, or friends, it blends laid-back...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 7
The Agave- 3 Bedroom Historic Cottage

Welcome to this beautiful 3-bedroom, 2-bathroom historic bungalow in downtown Charleston! Immerse yourself in the rich history and vibrant culture of Charleston while appreciating the comfort and convenience of this thoughtfully restored home.Step...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 8
La Rose | Bright and Comfortable Downtow...

Summary:Escape to La Rosa, a Charleston classic in the heart of downtown. With 3 bedrooms and 2 baths, this classy getaway is ideal for groups. Sip drinks on the second-floor balcony and appreciate the fresh breeze before heading to close by...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 8
Rose and Petunia Suites | Only 5 blocks ...
5.0
(2)

Permit Number: 04920,04921The Space: Located amidst all the action in the heart of downtown Charleston, our 4 bedroom/4 bathroom home, split into 2 separate apartments accessed by private exterior entrances, has been freshly modernized and...

  • Charleston
  • 4 Bedrooms
  • 4 Bathrooms
  • Sleeps 10
Suite Magnolia, Hot Tub & Pet Friendly, ...

Summary:Suite Magnolia is a gorgeous 2-bedroom home in Charleston's Avondale, ideal for friends or families. It features a private backyard with a HOT TUB and fire pit, and convenient access to downtown. This home offers modern amenities, beautiful...

  • Charleston
  • 2 Bedrooms
  • 1 Bathrooms
  • Sleeps 6