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Charleston, SC 2+ Bedroom Vacation Rentals

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1142 rentals found
PERFECT LOCATION...PARK, RELAX, & WALK! ...
4.9
(176)

For travelers protection, enhanced cleaning protocols have been put in place to include disinfecting all surfaces, handles, knobs, remotes...with additional care in disinfecting all areas of the bathrooms. Keypad is also disinfected & there is a no...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 4
Heart of Charleston | Stylish Home!

Summary:Step into your Charleston escape! A modren 4-bedroom, 4-bath getaway designed for comfort and connection. Ideal for families, groups, or friends traveling together, this roomy home combines modern finishes with timeless Southern...

  • Charleston
  • 5 Bedrooms
  • 4 Bathrooms
  • Sleeps 12
The Felix | Only 3 Blocks from King
4.8
(55)

Permit Number: 06252The Space: Set back off the busier streets of the Downtown Charleston area take a step into The Felix. With two bedrooms and two baths, this home is ideal for your four guests. Whether it be your modest family or a girls weekend...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 4
The Chapel | 4BR DT Charleston - Walk Ev...

Summary:Welcome to The Chapel, your downtown Charleston getaway combining historic appeal, modern amenities, and unbeatable walkability. Ideal for families, groups of friends, or modest gatherings, this 4-bedroom home offers style, comfort, and a...

  • Charleston
  • 4 Bedrooms
  • 4 Bathrooms
  • Sleeps 10
The King Suites at 493 - 8 Suites, 16 Be...

Permit Number: 004141The Space: Welcome to 493 Luxury Suites! These attractively appointed units are found on the second floor of a historic building on King Street (above Sewing Down South, as seen on “Southern Charm”).Step into the building...

  • Charleston
  • 16 Bedrooms
  • 16 Bathrooms
  • Sleeps 52
Lady Banks: Steps to Charleston's Best!
4.8
(65)

Permit Number: 06109The Space: Immerse yourself in the captivating appeal of The Lady Banks House, a meticulously remodeled two-bedroom getaway that seamlessly blends historic elegance and modern luxury. Step inside this enchanting abode and be...

  • Charleston
  • 2 Bedrooms
  • 3 Bathrooms
  • Sleeps 4
Charming 3 bedroom Home - 2 miles to bea...
4.6
(34)

GREAT LOCATION IN YOUR PRICE RANGE. Relaxing 3 bedroom, 1 bath. 2 MILES to Folly Beach. Sleeps 6 comfortably. Plenty of eateries, grocery stores and bars within walking distance. 5 miles to downtown Charleston. James Island County Park is 2...

  • Charleston
  • 3 Bedrooms
  • 1 Bathrooms
  • Sleeps 6
The Philip's Suite, newly renovated 3 Be...

Welcome to the Philip's Suite (Unit B) at 183 Saint Philip Street, your freshly remodeled Charleston haven 1 BLOCK from King Street! This new construction gem places you steps away from the city's vibrant attractions. Each bedroom features Serena ...

  • Charleston
  • 3 Bedrooms
  • 3 Bathrooms
  • Sleeps 8
Stunning Private Courtyard - 1 Block to ...
5.0
(4)

Welcome to The Palms of Charleston!Notable amenities include:- 1 Block to King St! Walk to Charleston’s Finest Dining, Shopping & Nightlife- Ideal for Sizable Groups – Families, Wedding Guests, Bachelor(ettes) & Work Retreats- Grand Private...

  • Charleston
  • 7 Bedrooms
  • 5 Bathrooms
  • Sleeps 14
The Sutton | Steps from King St | Histor...

Permit Number: 05957The Space: Welcome to the The Sutton Suites! Two separate units in the same building creating the ideal place for groups who also want privacy!Suite B:Offering an unparalleled getaway, inviting you to immerse yourself in...

  • Charleston
  • 3 Bedrooms
  • 3 Bathrooms
  • Sleeps 9
Charleston Coastal Cottage

Unwind in our cavernous and calming Coastal Cottage. Centrally located, 20 mins. from beaches, downtown Charleston, 15 mins. to airport & 5 mins. from Daniel Island where there are walking trails, eateries, grocery store, and much more! Guests have...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 7
Stunning, cozy, glamorous penthouse walk...

We're thrilled to share our unique living space with you, offering the ideal hideaway for an memorable vacation.Our property exudes a sense of warmth and coziness, but also fun & fantasy that will make you feel right at home. We've carefully curated...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 8
Downtown Duplex - Spring St - Sleeps 26
5.0
(1)

Feel the timeless appeal of Charleston’s historic peninsula, the Holy City. Stay just mins. from MUSC, the College of Charleston, and the vibrant shopping, dining, and nightlife of King Street. From this ideally located downtown home, you’ll be...

  • Charleston
  • 8 Bedrooms
  • 8 Bathrooms
  • Sleeps 26
The Lodge Alley Inn- historical Charlest...

Summary:This is a impressive place to stay in Historic Charleston that’s one block from the waterway on the Battery. Walking distance to Rainbow Row and Market St. The resort is actually a collection of 18th century warehouses that have been...

  • Charleston
  • 2 Bedrooms
  • 1 Bathrooms
  • Sleeps 4
? THE INNS ? Stunning 3BR/3BA - Heart of...
4.8
(39)

Summary:Welcome to one of Airbnb’s most appreciated homes, a 3-bedroom, 3-bath getaway that blends professional design with unmatched guest comfort. Perfectly located just two blocks from King Street, this property offers both vibrant access and...

  • Charleston
  • 3 Bedrooms
  • 3 Bathrooms
  • Sleeps 8
Long Term stay in 4-bedroom house in cha...

House available to rent for 3 month interval min. in 2026 beginning January 15, 2026. Located in Charleston, SC, appreciate all that this 4-bedroom designer home has to offer. With 4 bedrooms and 3.5 baths, guests will have plenty of space to...

  • Charleston
  • 4 Bedrooms
  • 3 Bathrooms
  • Sleeps 7
Historic Downtown Family Friendly Spacio...

Summary:Fauna House, a home constructed in 1905, features 4 cavernous bedrooms and 2 bathrooms, enhanced with relaxing green and blue accents that create a fresh, inviting ambiance. Bare brick fireplaces serve as striking focal points within the...

  • Charleston
  • 4 Bedrooms
  • 2 Bathrooms
  • Sleeps 10
Soho House | Prime Location, Walk to Eve...
5.0
(47)

Summary:Step into a classic Charleston getaway designed for guests who want history, comfort and convenience in one. This home is ideal for couples, families or modest groups looking to appreciate walkability, appeal and simple access to the...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 10