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Charleston, SC 2+ Bedroom Vacation Rentals

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1142 rentals found
The Sterling | 4BR DT Charleston - Best ...

Summary:Welcome to The Sterling, your vibrant downtown Charleston getaway where style, space, and location align delightfully. Ideal for families or groups of friends, this 4-bedroom home offers a private porch, thoughtful design elements, and...

  • Charleston
  • 4 Bedrooms
  • 3 Bathrooms
  • Sleeps 10
Across from MUSC. Perfect for interns mi...

Welcome to 40 Bee! We are located in the Cannonborough Elliottborough neighborhood of the downtown district across the street from MUSC, making this the prime location for students and medical professions. Whether you are traveling for business or...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 2
Location! Minutes to Downtown and Folly ...

Summary:Welcome to our striking 3-bed, 2-bath 1940s home in the heart of the impressive Riverland Terrace neighborhood! Savor the open kitchen living and mid-century modern design of this refreshed bungalow. Riverland Terrace was once an Indigo...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 6
Casa Fuego A - Old School Charm
4.5
(13)

Permit Number: 06047The Space: Our cavernous ground floor condo, ‘Casa Fuego Suite A’, is ideal for groups of 3-5 guests with 2 bedrooms, and 1 full bath. 1 king bed, 1 queen bed, and a pull-out couch. Located just off Spring Street, location...

  • Charleston
  • 2 Bedrooms
  • 1 Bathrooms
  • Sleeps 5
Historic, newly renovated, 1 block off u...

Located in the heart of the historic district. 1 block off of upper King Street. Everything is a convenient walk...to great eateries, museums, music, Marion square, MUSC hospital....Home was originally constructed in 1906 and freshly completely...

  • Charleston
  • 2 Bedrooms
  • 1 Bathrooms
  • Sleeps 4
Soho House | Prime Location, Walk to Eve...
5.0
(47)

Summary:Step into a classic Charleston getaway designed for guests who want history, comfort and convenience in one. This home is ideal for couples, families or modest groups looking to savor walkability, appeal and painless access to the city’s...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 10
Waterfront Gem in the heart of James Isl...
5.0
(10)

Summary:Located in the serene environment of James Island, our waterfront property offers a secluded hideaway that feels like a world apart, yet remains connected to everything you need. This newly constructed two-bedroom, two-bathroom unit provides...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 5
Top-Floor Retreat | Walk to King St + Pr...
4.8
(5)

Summary:This welcoming two-bedroom, two-bath apartment offers visitors convenient access to all that Charleston has to offer. Located on the third floor of a historic Charleston single home constructed in the late 1800s, and set back from the street...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 4
The Pineapple Pad | EastBay Historic Dis...
4.7
(64)

Summary:Welcome to your Charleston sanctuary where historic appeal meets cavernous luxury. This 5-bedroom getaway offers a generous 3,000 square feet of attractively appointed space. Ideal for families or groups who want elegant design, room to...

  • Charleston
  • 5 Bedrooms
  • 4 Bathrooms
  • Sleeps 16
Luxury yacht in downtown Charleston, SC
4.8
(163)

Savor the gorgeous sunset and watch Charleston's resident pod of dolphins as you stay on our 2 Bedroom/2 bathroom 40' yacht! Park for complimentary at our amazing location on the Ashley River and the peninsula of elegant downtown Charleston, SC...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 6
Lady Helène No. 1: Stylish Comfort Step...

Permit Number: 05609The Space: Welcome to Lady Helene, Suite A, A charmingly refreshed home in the heart of downtown Charleston, steps away from King Street and close to all the most trendy attractions. Step into the open-concept living, dining, and...

  • Charleston
  • 3 Bedrooms
  • 3 Bathrooms
  • Sleeps 6
The Apollo
4.9
(14)

Welcome to The Apollo! We are located in the heart of Avondale in West Ashley — a highly charming neighborhood that’s only 10 mins. (2.5 miles) from downtown and 15 mins. (10 miles) from Folly Beach. Within 0.5 miles, there are a dozen...

  • Charleston
  • 3 Bedrooms
  • 1 Bathrooms
  • Sleeps 8
Historic and Bright 2-BR Apt Downtown

A handsome historic apartment in the heart of the Eastside neighborhood in downtown Charleston, this space has all of the original features that make Charleston homes unique with all of the amenities of modern living. You'll experience life as a...

  • Charleston
  • 2 Bedrooms
  • 1 Bathrooms
  • Sleeps 4
The Charlee Flats | NEW 4BR Urban Oasis ...

Summary:Stay at The Charlee on Cannon, a brand-new 4BR, 3BA condo blending modern luxury with Charleston appeal. Unwind in the open living area, relax on the private balcony, or appreciate rooftop seating with city vistas. Each bedroom features a...

  • Charleston
  • 4 Bedrooms
  • 3 Bathrooms
  • Sleeps 10
Downtown Historic Home Close to Neighbor...

Summary:Welcome to this pretty and vibrant downtown home, originally constructed in 1905 and freshly remodeled to modern standards. Bursting with color and character, each of the eight cavernous bedrooms offers a distinct personality, complemented...

  • Charleston
  • 8 Bedrooms
  • 4 Bathrooms
  • Sleeps 20
The Charleston Suites: The Emerson Suite
5.0
(9)

The Emerson Suite:>> Prime Location: Ideal escape from busy streets>> Quick walk to beverages, dinner + shopping>> 15 min drive to the beach>> Balcony for private dining>> Professionally turfed backyard with pergola + grille>> Beds for 6 guests>...

  • Charleston
  • 3 Bedrooms
  • 1 Bathrooms
  • Sleeps 6
PERFECT LOCATION...PARK, RELAX, & WALK! ...
4.9
(176)

For travelers protection, enhanced cleaning protocols have been put in place to include disinfecting all surfaces, handles, knobs, remotes...with additional care in disinfecting all areas of the bathrooms. Keypad is also disinfected & there is a no...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 4
Quaint Townhome in the Heart of Charlest...

The resort is an Historic 18th century warehouse that has been lovingly restored to preserve the history while also providing guests with all the modern-day amenities and amenities. Savor an afternoon cap of sherry and some fresh baked cookies after...

  • Charleston
  • 2 Bedrooms
  • 1 Bathrooms
  • Sleeps 6