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Charleston, SC 2+ Bedroom Vacation Rentals

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1050 rentals found
8D at Saint Philip Square, One Block to ...

Welcome to appealing Saint Philip Square, a esteemed collection of 5 historic homes spanning nearly a city block of downtown Charleston. The Alexander Wilson House at 178 Unit D Saint Philip Street is a beautiful 3BD/2BA upstairs unit blending...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 7
The Prickly Pear | Next To Local Cafe an...

Permit Number: 05284The Space: Welcome to The Prickly Pear, a charmingly remodeled 1880s Charleston home that blends historic appeal with vibrant modern style in the heart of downtown!This thoughtfully designed getaway offers open living spaces and...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 4
5BR Group House | Fire Pit, Movie Deck &...

Bold, bright, and constructed for your whole crew! The entire property is yours, both private units, every bedroom, no one else on site. This Charleston group home sleeps 13 across 5 bedrooms and 3 baths. Packed with arcade games, a fire pit for...

  • Charleston
  • 5 Bedrooms
  • 3 Bathrooms
  • Sleeps 13
4BR Group Retreat, Walk to King St

Summary:Welcome to Blue Magnolia, a cavernous and handsomely designed Charleston getaway ideally suited for family vacations, group getaways, wedding weekends, and special celebrations. Located in the heart of downtown Charleston, this inviting home...

  • Charleston
  • 4 Bedrooms
  • 2 Bathrooms
  • Sleeps 10
Club Ed Charleston

Club Ed is on James Island 5 mins to Downtown Charleston & 10 mins to Folly Beach. Club Ed sits on a 1/2 acre of mature landscaping that include azaleas, magnolias, camellia s and sizable Oak trees. Savor laying in the enormous hammock, sitting on...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 6
The Blue Chip | Large Veranda | Al Fresc...

Summary:Welcome to The Blue Chip, a really unique Charleston property rich in history and character. Once a bustling 20th-century nightclub, this completely refreshed home now blends eclectic appeal with modern comfort. With three bedrooms, two full...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 6
Royal Cottage II –  Light, Art, & Loca...

Summary:OP2025-06817Royal Cottage II is a modern-meets-historic Casa Zoë sanctuary. Designed with soul, light, and intention. Featuring four thoughtfully appointed bedrooms (each with ensuite baths), vaulted ceilings, wood floors, and...

  • Charleston
  • 4 Bedrooms
  • 5 Bathrooms
  • Sleeps 8
Whimsical Historic Retreat! | Globetrott...

Permit Number: 07176The Space: Welcome to Globetrotter – Suite C — a bright, cavernous first-floor getaway in the heart of downtown. With 2 bedrooms, 2 ensuite baths, and an open-concept layout, it’s a comfortable home base for up to 4...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 4
Southern Charm - Elevated home minutes t...

Embark on an memorable beach hideaway at Southern Charm, strategically positioned just moments from Folly Beach and close to downtown Charleston. This two-story, elevated home offers both comfort and convenience, providing simple access to Folly...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 6
Folly Beach Marsh View Condo

Winter 30 day+ discount available. Dedicated work space + WiFi Welcome to Folly Beach! This cavernous, marsh view, 3 bedroom, 3 bathroom condo is the ideal vacation spot for up to 6 guests. Bedroom 1 has 1 King bed with an attached bathroom with a...

  • Charleston
  • 3 Bedrooms
  • 3 Bathrooms
  • Sleeps 6
Renovated West Ashley Retreat, Near Down...

This entirely furnished, freshly modernized home is located in a peaceful, well-established West Ashley neighborhood, ideally positioned near all of Charleston’s top attractions. Guests savor a convenient 12-min. drive to Downtown Charleston and...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 1
Downtown Duplex - St Philip St

Feel the timeless appeal of Charleston’s historic peninsula, the Holy City. Stay just mins. from MUSC, the College of Charleston, and the vibrant shopping, dining, and nightlife of King Street. From this ideally located downtown home, you’ll be...

  • Charleston
  • 6 Bedrooms
  • 5 Bathrooms
  • Sleeps 16
Historical 2bd Home w. Outdoor Space + P...

Summary:Welcome to The Fleetwood, a freshly modernized, historical home in the heart of Downtown Charleston. Rich with architectural detail, this unique 2BR/2.5BA two-story suite offers a private back porch overlooking a peaceful garden, fountain...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 4
8B at Saint Philip Square, One Block to ...

Welcome to Saint Philip Square, an award-winning collection of historic homes spanning nearly one city block of downtown Charleston. The Alexander Wilson House at 178 Unit B Saint Philip St. is a 2-bed 2-bath gem blending modern comfort with...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 6
Great for Groups | Private Patio | The Z...

Permit Number: 06281The Space: Welcome to Zeus — a freshly redesigned second-floor getaway constructed for comfortable group stays. With 5 bedrooms and 4.5 bathrooms across two upper levels, this roomy home gives families and bigger groups room to...

  • Charleston
  • 5 Bedrooms
  • 4 Bathrooms
  • Sleeps 12
Dreamy Downtown Condo, Near Meeting St &...

Summary:Located in the heart of downtown Charleston, between King Street and Meeting Street, this striking condo offers the ideal blend of comfort and convenience. Savor being just steps away from fine dining, boutique shopping, and historic...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 7
Charming Waterfront Cottage only 2 miles...

Gorgeously-restored 1920's bungalow with heart-pine floors and tongue-and-grove wood walls and ceilings. This bungalow is a must for a comfortable and calming visit to Charleston, located on a peaceful country lane yet only two miles to Historic...

  • Charleston
  • 3 Bedrooms
  • 3 Bathrooms
  • Sleeps 6
The Perfect Family Escape | The Barbuda

Permit Number: 06409The Space: Welcome to Barbuda House, a gorgeously refreshed 1880s Charleston home blending timeless Southern appeal with modern luxury in the heart of downtown!This thoughtfully designed getaway offers four private ensuite...

  • Charleston
  • 4 Bedrooms
  • 4 Bathrooms
  • Sleeps 8