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Charleston, SC 2+ Bedroom Vacation Rentals

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1055 rentals found
The Quad at 493 - 4 Suites - Right on Ki...

Permit Number: 004141The Space: Welcome to 493 Luxury Suites! These charmingly appointed units are found on the second floor of a historic building on King Street (above Sewing Down South, as seen on “Southern Charm”).Step into the building...

  • Charleston
  • 8 Bedrooms
  • 8 Bathrooms
  • Sleeps 24
Marsh front home 10 min to beach and dow...

Welcome to life in the Lowcountry at The Lookout! The design of this home embodies the natural beauty of life on the water with comfort and style. Heated pool just installed! Great place to cool off year round- close to the outdoor TV...

  • Charleston
  • 5 Bedrooms
  • 6 Bathrooms
  • Sleeps 12
Downtown Historic Home Steps to King St

Summary:Welcome to this beautiful Southern bungalow, where classic elegance meets modern comfort. This enchanting home features four cavernous bedrooms and two handsomely appointed bathrooms, ideal for family living or entertaining guests. The...

  • Charleston
  • 4 Bedrooms
  • 2 Bathrooms
  • Sleeps 12
Downtown Duplex - Spring St

Feel the timeless appeal of Charleston’s historic peninsula, the Holy City. Stay just mins. from MUSC, the College of Charleston, and the vibrant shopping, dining, and nightlife of King Street. From this ideally located downtown home, you’ll be...

  • Charleston
  • 8 Bedrooms
  • 8 Bathrooms
  • Sleeps 26
The OakTree | Stylish Bohemian Downtown ...

Summary:Welcome to The OakTree, your boho-chic haven in the heart of downtown Charleston, where artistic flair meets generous space. Ideal for enormous groups, families, or creative retreats, this 7-bedroom home offers character, comfort, and close...

  • Charleston
  • 7 Bedrooms
  • 7 Bathrooms
  • Sleeps 16
Private, Historic Apartment, Downtown Lu...

Summary:The Kiawah Suite features gorgeous two queen bedrooms and two baths, as well as a full kitchen, living space, private patio, porch, and parking. Located on the 1st floor of The Charlestonian, a historic downtown home overlooking Cannon...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 4
Rooftop Patio, Unparalleled Views in 3-s...

Summary:Feel the appeal of Carriage on Cannon, a striking 3-bedroom home in downtown Charleston. Savor the elegance of this three-story residence, complete with porches and a rooftop patio offering pretty expansive city vistas. Located just two...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 6
Downtown Charleston – Walk to Dining &...

Summary:This welcoming 3-bedroom, 3-bath apartment offers visitors convenient access to all the city has to offer. Located on the first floor of a historic Charleston site, and set back from the street with off-street parking, the rental overlooks...

  • Charleston
  • 3 Bedrooms
  • 3 Bathrooms
  • Sleeps 6
93.5 A&B - New listing! 6 Bedrooms Close...

The property located at 93.5 unit A & B The Manor is a gorgeous two-story new construction home providing all the amenities of home combined with classy furnishings and an spectacular location.Unit A is the first-floor unit with an open concept...

  • Charleston
  • 6 Bedrooms
  • 6 Bathrooms
  • Sleeps 16
Zuma Suite | Walk to King Street Shops!

Summary:Welcome to your classy escape, a thoughtfully designed getaway that blends clean modern interiors with comfortable appeal. Ideal for couples, solo travelers or modest groups, this property offers comfort, convenience and access to the very...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 5
Charleston The Perfect Dream Stay

What makes our place special is the Charleston appeal. From the moment you arrive, you’ll feel the casual Lowcountry ambiance. Step outside and you’re surrounded by historic streets, amazing food, and the welcoming energy that makes Charleston...

  • Charleston
  • 3 Bedrooms
  • 1 Bathrooms
  • Sleeps 6
19 Bedrooms in CHS | Private Pool | The ...

Permit Number: 06280The Space: After February 2026, savor a brand-new private pool in the enclosed backyard, photos coming soon!Welcome to your ultimate group hideaway. This broad 4-unit, 19-bedroom property is thoughtfully designed for sizable...

  • Charleston
  • 19 Bedrooms
  • 15 Bathrooms
  • Sleeps 38
The Jessamine | 9BR Historic Downtown Ab...

Summary:Welcome to your Cannonborough hideaway, a newly refreshed 3-unit property just one block from iconic King Street. Ideal for families or groups of friends, this getaway blends comfort, style, and convenience. With updated interiors, a calming...

  • Charleston
  • 9 Bedrooms
  • 5 Bathrooms
  • Sleeps 16
Downtown 2 bedroom, 2 bath, pet friendly...

******Please note this unit is for sale. Honey Bee, one of Charleston's Finest, is a 2 bedroom 2 bath freshly refreshed apartment in the heart of historic downtown Charleston. It is available for units of 30 days or longer. It is the ideal home away...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 4
Kings Corner- Entire Historic Charleston...

Welcome to King`s Corner- An entire 2-story, 4 bedroom, 5 and a half bathroom, historic Charleston home in Downtown Charleston, just off King Street!This freshly refreshed historic home provides all the modern amenities you need in downtown...

  • Charleston
  • 4 Bedrooms
  • 6 Bathrooms
  • Sleeps 12
Sunny Haven Retreat near Folly w/ Backya...

Discover a comfortable coastal escape conveniently located just mins. from Folly Beach or Downtown Charleston! Our beautiful 4br/2ba home is the ideal getaway, featuring a refreshed interior that has been charmingly decorated. Savor the outdoors in...

  • Charleston
  • 4 Bedrooms
  • 2 Bathrooms
  • Sleeps 8
Location + Luxury  3BD/3BA - 2 Blocks to...

Summary:Welcome to your Charleston luxury getaway, a freshly styled 3-bedroom, 3-bath home that pairs fresh comfort with superb location. Ideal for those who want refined interiors and walk-everywhere convenience, this property sits just two blocks...

  • Charleston
  • 3 Bedrooms
  • 3 Bathrooms
  • Sleeps 6
Cozy & beautiful home in Charleston mins...

An striking and calming hideaway. This property has a minimum of 30 days rental. This home is entirely equipped, located in a family friendly neighborhood with the appeal and vibe of Folly Beach. A roomy 3br, 2 bath home with master suite , open...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 6