Charleston-SC.com logo

Charleston, SC 2+ Bedroom Vacation Rentals

Filter 2+ Bedroom Charleston Properties by: Company | Oceanfront | Pet-Friendly | or choose different a Area or Bedrooms
No company options available.
Bedrooms:
1052 rentals found
Spacious Historic Home, Downtown + Walka...

Summary:Welcome to The SpringHouse, a elegantly restored historic Charleston residence where timeless architecture meets elevated modern design. Located in the heart of downtown Charleston, this exclusive two-level getaway occupies the second and...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 7
5BR Charleston Oasis w/ Screened Porch f...

Why you`ll adore The TropicFive roomy bedrooms, with a master that treats you to a king bed and rainfall shower. Parlor year-round on the giant screened porch, or fire up the grille in your private jungle yard with a dining deck under the pines...

  • Charleston
  • 5 Bedrooms
  • 2 Bathrooms
  • Sleeps 12
Chic Downtown 2bd Retreat with Parking

Summary:Discover Charleston from our classy 2-BR top-floor apartment on Spring Street! Located in a historic Victorian home, this sun-filled getaway comfortably sleeps 4. Features a king bed, dedicated workspace, and a kitchenette. Appreciate modern...

  • Charleston
  • 2 Bedrooms
  • 1 Bathrooms
  • Sleeps 4
5BR Group House | Fire Pit, Movie Deck &...

Bold, bright, and constructed for your whole crew! The entire property is yours, both private units, every bedroom, no one else on site. This Charleston group home sleeps 13 across 5 bedrooms and 3 baths. Packed with arcade games, a fire pit for...

  • Charleston
  • 5 Bedrooms
  • 3 Bathrooms
  • Sleeps 13
Hidden Gem • Close to Downtown & Beach...

Summary:Welcome to Lowcountry Lookout ???? A relaxing marsh front getaway in the heart of West Ashley! Surrounded by handsome oak trees, you’re just mins. from Charleston’s top attractions, eateries, beaches, and historic sites. Unwind by the...

  • Charleston
  • 4 Bedrooms
  • 2 Bathrooms
  • Sleeps 8
Large 6bd Home, right off King

Summary:Welcome to the Aurelia House, a enormous 6-bedroom home constructed for families, groups, or multi-family gatherings who want space, comfort, and access. Located a short walk from King Street, this home blends old Charleston spirit with...

  • Charleston
  • 6 Bedrooms
  • 4 Bathrooms
  • Sleeps 14
3 bedroom marsh & sunset views. NON SMOK...

Keep it simple at this peaceful (no smoking,) centrally-located freshly constructed home, constructed with travelers in mind. Pefectly located 3 miles from Folly Beach, a short mile to grocery store or Bowens Island & 8 miles from Historic...

  • Charleston
  • 3 Bedrooms
  • 3 Bathrooms
  • Sleeps 8
Historic Charleston Single w/ Private Ou...

Feel the timeless appeal of Charleston’s historic peninsula, the Holy City. Stay just mins. from MUSC, the College of Charleston, and the vibrant shopping, dining, and nightlife of King Street. From this ideally located downtown home, you’ll be...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 10
2 bed/ 2 bath! Fenced in yard-close to t...

Stylish, sleek townhome modernized in 2024! Modern touches with all the bells & whistles. Great location on James Island. Roughly 10 mins. to Folly Beach and also downtown Charleston. Ideal setup for retirees, traveling nurses, young professionals...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 4
The Sweetgrass Suite - Newly Renovated -...

Feel the timeless appeal of Charleston’s historic peninsula, the Holy City. Stay just mins. from MUSC, the College of Charleston, and the vibrant shopping, dining, and nightlife of King Street. From this ideally located downtown home, you’ll be...

  • Charleston
  • 2 Bedrooms
  • 1 Bathrooms
  • Sleeps 4
Spring St 2 Bedroom - 3 Blocks to King S...

Feel the timeless appeal of Charleston’s historic peninsula, the Holy City. Stay just mins. from MUSC, the College of Charleston, and the vibrant shopping, dining, and nightlife of King Street. From this ideally located downtown home, you’ll be...

  • Charleston
  • 2 Bedrooms
  • 1 Bathrooms
  • Sleeps 4
2 Beds 2 Full Baths - Dog Friendly!

Welcome to this very comfortable, yet roomy town home in one of the best locations on James Island. Very cute and safe neighborhood with walking trails and a handsome pond. Just a 10 min. drive to Folly Beach and Downtown, and walkable to the local...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 4
1905 Victorian Historic Home Just 2 Bloc...

Summary:Stay at our handsome 1905 Charleston Victorian home in the heart of Cannonborough. Just 2 blocks from King Street, this property features 3 full-sized bedrooms with king beds and 3.5 bathrooms.The Space:The 3 full bedrooms all include King...

  • Charleston
  • 3 Bedrooms
  • 3 Bathrooms
  • Sleeps 6
Charming downtown apartment just steps t...

Summary:Charleston SweetThe Space:Charleston Sweet is a bright, modern Southern getaway tucked into the heart of downtown Charleston’s beloved Cannonborough–Elliottborough district. Here, the city doesn’t rush you - it invites you in. Mornings...

  • Charleston
  • 2 Bedrooms
  • 1 Bathrooms
  • Sleeps 6
Waterfront Home in Charleston with Kayak...

Escape to a serene waterfront getaway ideally located between downtown Charleston and Folly Beach. This property is a nature-lover's heaven on half an acre of Charleston appeal. Appreciate fishing, crabbing, kayaking, and bird watching from the...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 7
Just Blocks from King St | Sweetgrass (S...

Permit Number: 06475The Space: Welcome to Sweetgrass (Suite B), a bright and welcoming second floor condo designed for comfort and simple Charleston living. Ideal for up to four guests, this inviting home offers a casual getaway just off Spring...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 4
Park-View Light-Filled Condo + Elevator ...

The Edison – Light-Filled Condo Overlooking Dereef ParkAppreciate elevated Charleston living at The Edison, a delightfully designed 2-bedroom, 2.5-bath condo located in the vibrant Cannonborough-Elliotborough neighborhood. Overlooking Dereef Park...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 4
30-Day Rental | Downtown| Backyard

Summary:Utilities Supplied | Pro cleaning services available for a fee 45 Rose Lane is a appealing 3-bedroom, 2.5-bath home in downtown Charleston, available for 30+ day stays. Savor roomy accommodations, comfortable living areas, and a sizable...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 6