Charleston-SC.com logo

6+ Bedroom Vacation Rentals

Filter 6+ Bedroom Properties by: Area | Company | Oceanfront | Pet-Friendly | or choose different Bedrooms
No company options available.
Bedrooms:
176 rentals found
The Trio at 493 - 3 Suites - On King!

Permit Number: 004141The Space: Welcome to 493 Luxury Suites! These charmingly appointed units are found on the second floor of a historic building on King Street (above Sewing Down South, as seen on “Southern Charm”).Step into the building...

  • Charleston
  • 6 Bedrooms
  • 6 Bathrooms
  • Sleeps 18
One Block to Beach! Modern 6 Bed with Pr...

This splendid 6 bedroom/6 bathroom home is located in an ideal location on the island: one block from the ocean with a direct beach access path, a short distance to the IOP Marina, and walking distance to the Citadel beach home. The peaceful...

  • Isle of Palms
  • 6 Bedrooms
  • 6 Bathrooms
  • Sleeps 12
Casa Zoë | Royal House – Charleston...

Summary:OP2025-06816OP2025-06817The Royal House is Charleston’s ultimate group escape: a dual-unit Casa Zoë mansion that blends grandeur, design, and independence. With 8 bedrooms, 8 baths, and separate living quarters, it offers shared elegance...

  • Charleston
  • 8 Bedrooms
  • 10 Bathrooms
  • Sleeps 16
Wonderful New Construction Home w/ Priva...

Check your cares at the door and relax in this pretty vacation home! Two blocks from the beach, and just steps away from the Wild Dunes Resort this home offers the best of both worlds, coupled with your own private pool, all of the boxes are checked...

  • Isle of Palms
  • 6 Bedrooms
  • 7 Bathrooms
  • Sleeps 12
Luxury Oceanfront- Private Pool, Hot Tub...

Choose luxury, convenience, and comfort when you look for a vacation rental at the handsome Isle of Palms. If you excited to savor this charming beach destination with your appreciated ones, you can stay at our oceanfront home at 700 Ocean Blvd...

  • Isle of Palms
  • 6 Bedrooms
  • 6 Bathrooms
  • Sleeps 14
3 Blocks to King Street | 6 BR | Maison ...

Permit Number: 05740The Space: Stay in the heart of Charleston in this attractively restored 1890s home just steps from King Street, offering six bedrooms and six and a half bathrooms across two private floors, ideal for sizable groups seeking...

  • Charleston
  • 6 Bedrooms
  • 6 Bathrooms
  • Sleeps 13
Designer Chic 6BR Full Downtown Charlest...

Feel the timeless appeal of Charleston’s historic peninsula, the Holy City. Stay just mins. from MUSC, the College of Charleston, and the vibrant shopping, dining, and nightlife of King Street. From this ideally located downtown home, you’ll be...

  • Charleston
  • 6 Bedrooms
  • 4 Bathrooms
  • Sleeps 14
2 Luxury Houses w/ Patios | 1 Block from...

Summary:Discover luxury pair of completely refreshed luxury homes ideal for a sizable group, located next door to each other just moments from King St. Indulge in beautiful interiors awash with natural light from wrap-around windows. These...

  • Charleston
  • 8 Bedrooms
  • 7 Bathrooms
  • Sleeps 20
Historic Charm | The Bee & Blossom

Permit Number: 06191The Space: Welcome to The Bee and Blossom, a attractively reimagined historic 6-bedroom, 6.5-bath home in the laid-back Radcliffborough neighborhood, thoughtfully designed for groups of up to twelve guests!Spanning three roomy...

  • Charleston
  • 6 Bedrooms
  • 6 Bathrooms
  • Sleeps 12
IDEAL IOP Beach Home, 6 BR, Private Pool...

This elegant 6 bedroom, 6.5 bathroom home is ready to welcome you for a once-in-a-lifetime beach escape. Just one block to the beach, it has all you need to make incredible memories on the Isle of Palms. It features two living rooms, a entirely...

  • Isle of Palms
  • 6 Bedrooms
  • 6 Bathrooms
  • Sleeps 12
Discounts!! Serenity- 2 50th One of a ki...

Ask about our Summer 2026 discounts!! *During Summer months this home books Friday to Friday**Plug in your dates to see the full quote! Email us with any questions regarding the home or the quote. --Description--New to our Luxury Collection...

  • Isle of Palms
  • 6 Bedrooms
  • 5 Bathrooms
  • Sleeps 12
Guesthouse Charleston: WEST (242 B & C)

West 242 B and 242 C are two appealing standalone homes located in the heart of Charleston's vibrant Cannonborough/Elliotborough neighborhood, just two blocks from historic King Street. This prime location offers simple access to Charleston's best...

  • Charleston
  • 8 Bedrooms
  • 6 Bathrooms
  • Sleeps 16
Beautiful Ocean Views w/ Pool and Elevat...

2301 Palm BoulevardProperty Highlights- Enormous Private Pool - Can Be Heated - Across the Street from Beach Access Path- Rooftop Deck with Ocean Vistas- Elevator- $250 Beach Gear Credit with 3-14 nighttime stays!Please note that every reservation...

  • Isle of Palms
  • 6 Bedrooms
  • 5 Bathrooms
  • Sleeps 14
The Manor 93 A&B - 2 Newly Renovated Uni...

Welcome to 93 Spring Street, a attractively restored 1880's Charleston home that combines historic appeal with modern amenities. Located just two and a half blocks from King Street, this cavernous home has been thoughtfully divided into two separate...

  • Charleston
  • 7 Bedrooms
  • 7 Bathrooms
  • Sleeps 14
11 Bed Compound for Large Groups, Prime ...

Summary:Welcome to The Grandiose Estate, a private getaway in the heart of downtown Charleston, SC. Located within a meticulously restored historic home, this exclusive property features four entirely furnished residences, creating the ideal setting...

  • Charleston
  • 11 Bedrooms
  • 8 Bathrooms
  • Sleeps 24
Downtown 9BR Mansion with Parking

Summary:Feel Charleston in this grandiose 9-bedroom Victorian mansion, ideal for huge groups. Recently refreshed with two full kitchens and beautiful decor, this home comfortably accommodates your entire event. Located in the heart of the city, this...

  • Charleston
  • 9 Bedrooms
  • 6 Bathrooms
  • Sleeps 16
Coastal Manor~ 6 bdrm, across from ocean...

** During the summer we book Friday to Friday. Off-season we require a 3 nighttime minimum **--Description--'Coastal Manor' is a brand new bespoke constructed home located on Palm Blvd. right across from the ocean with a convenient beach access just...

  • Isle of Palms
  • 6 Bedrooms
  • 6 Bathrooms
  • Sleeps 12
Whole House|Downtown|Sleeps 16

Summary:Welcome to The Ivory and Oak Lofts, a gorgeous 8-bedroom, 6-bathroom historic home located in the heart of Charleston. This handsomely restored property blends timeless appeal with modern amenities, offering an exceptional space for sizable...

  • Charleston
  • 8 Bedrooms
  • 6 Bathrooms
  • Sleeps 16