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Isle of Palms, SC 2+ Bedroom Vacation Rentals

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356 rentals found
'Isle be Back' 5 57th Ave- Great Ocean V...

**Summer bookings are Sat. to Sat. We have a 3 nighttime min in the off-season** Description"Isle be Back" - 5 57th Avenue is one of our newest additions. It is a enchanting, six bedroom, five and a half bathroom inverted floor plan home with...

  • Isle of Palms
  • 6 Bedrooms
  • 5 Bathrooms
  • Sleeps 16
Camp Carolina 3BR 2BA home with private ...

Camp Carolina has a private pool and is close to the beach and Downtown Isle of Palms. This home is located on Carolina Blvd and is in a location which accepts for walking to the beach, eateries, live music and stores. The beach path is only a 2...

  • Isle of Palms
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 7
208 B Shipwatch by AvantStay | Ocean Vie...

208 B Shipwatch is a blissful place you and your family will not want to leave! Pamper yourself in this fantastic condominium that is one of the best on the Island. Featuring three bedrooms and three full baths, your family will be spoiled with...

  • Isle of Palms
  • 3 Bedrooms
  • 3 Bathrooms
  • Sleeps 8
3 Twin Oaks Lane by AvantStay | Beach Ac...

It is said that "family holidays are valued by kids, both in the moment and for long afterward in their memory". 3 Twin Oaks Lane is ready to welcome your family to their next fabulous memory while spending a holiday at the beach!3 Twin Oaks Lane...

  • Isle of Palms
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 6
IOP 6BD Only 3 Min Walk to Beach w/ Priv...

Welcome to #19 on 21st Avenue on the Isle of Palms! Constructed in 2019, this marvelous 6 bedroom Isle of Palms home is a 3400 square foot gem! With two enormous living areas and cavernous bedrooms that comfortable sleeps 12 guests, it's ideal for...

  • Isle of Palms
  • 6 Bedrooms
  • 5 Bathrooms
  • Sleeps 12
Award-Winning Resort Amenities | Lagoon ...

Lagoon Villa 14 by Wild Dunes2 Bedrooms | 2 Bathrooms | Sleeps 6 | Resort View________________________________________Set alongside a calming lagoon, this 1218 Sq. Ft. Lagoon Villas home provides a calming coastal getaway with access to a complex...

  • Isle of Palms
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 6
Award-Winning Resort Amenities | Racquet...

Racquet Club Villa 32 by Wild Dunes2 Bedrooms | 2 Bathrooms | Sleeps 6 | Resort View________________________________________Savor a prime 1268 Sq. Ft. location near pools, eateries, main beach access and shopping. This lively community offers both...

  • Isle of Palms
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 6
Stunning Home! Pool, Theater Room, Steps...

$200 Gift Card Special for WEEK stays!Qualifying weeks are - June 27th - July 11th. Amazing luxury rental located on a peaceful street just a few steps to the beach boardwalk. Loaded with outdoor amenities including an broad backyard complete...

  • Isle of Palms
  • 5 Bedrooms
  • 5 Bathrooms
  • Sleeps 11
Oceanfront Villa in Wild Dunes w/2 Maste...

Construction Notice: Building 1 will be undergoing major renovations during 2025. This condo is located in Building 4 and will be impacted by noise. Please inquire for more details prior to booking. We are excited to see all of the amazing exterior...

  • Isle of Palms
  • 4 Bedrooms
  • 4 Bathrooms
  • Sleeps 10
Centrally located condo, Renovated, Pool...

Ideal couples or modest family getaway! Freshly modernized condo in central location on Isle of Palms. 204A Oceanside provides simple access to the Island's main strip including a variety of eateries, live music, local stores, and the county park...

  • Isle of Palms
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 6
Oasis w/ Private Pool, Pets considered, ...

Welcome to your hideaway getaway at The Pink House! 5 Bedroom, 3 Bathroom home with all new refreshed bathrooms as of 2023, a 50ft long private pool, and less than a 2 min. walk to the beach. The pool has two 6 in wading areas that is great for...

  • Isle of Palms
  • 5 Bedrooms
  • 3 Bathrooms
  • Sleeps 10
Great IOP Palm Blvd home! Pet friendly, ...

Welcome to your dream beach vacation rental on the Isle of Palms! Located at 4403 Palm Boulevard, this attractively remodeled 4-bedroom, 4.5-bath Southern-style home is attractively located just 500 feet—or one short block—from the pristine...

  • Isle of Palms
  • 4 Bedrooms
  • 4 Bathrooms
  • Sleeps 10
311 Summerhouse by AvantStay | Beach Vie...

A striking pearl might surprise you when opening an oyster, but you will always find a handsome vacation when opening the door at 311 Summerhouse. This fabulous oceanfront, three-bedroom and three bath condominium freshly experienced an broad...

  • Isle of Palms
  • 3 Bedrooms
  • 3 Bathrooms
  • Sleeps 7
Prime Grand Pavilion Location! Steps fro...

Located in the heart of Wild Dunes Resort and just steps from the Atlantic Ocean, this special oceanfront home is the ideal spot for an Isle of Palms vacation! This gem is a 4 bedroom, 4 bathroom home located directly on the trendy Grandiose...

  • Isle of Palms
  • 4 Bedrooms
  • 4 Bathrooms
  • Sleeps 10
Saltwater Sanctuary | Ocean Views + Priv...

The Delaney House – Relaxed Coastal Luxury on Isle of PalmsWelcome to The Delaney House, a charmingly refreshed Isle of Palms getaway where ocean vistas, casual coastal interiors, and a private saltwater pool create the ideal backdrop for an...

  • Isle of Palms
  • 5 Bedrooms
  • 3 Bathrooms
  • Sleeps 10
Modern Beach Home w/Private Pool, 3 Mast...

802 Palm BlvdIf you're ready to take a deep dive into the luxury lifestyle on Isle of Palms, SC, then this is the property for you! This marvelous 4-bedroom home has 4 bathrooms and 2 half bathrooms, and ideally sets you up to experience all the...

  • Isle of Palms
  • 4 Bedrooms
  • 5 Bathrooms
  • Sleeps 10
Modern Oceanview Villa in Wild Dunes Res...

Located just 50 yards from the beach in Wild Dunes Resort, this attractively refreshed Mariners Walk condo now features a freshly updated kitchen and refreshed dining space—ideal for your island hideaway. With 3 bedrooms and 3 bathrooms, it offers...

  • Isle of Palms
  • 3 Bedrooms
  • 3 Bathrooms
  • Sleeps 8
Oceanfront! Pool, Hot Tub, Walk to Town,...

$250 gift card for WEEK stays!Qualifying weeks are - May 30-June 6, June 13-20th, Aug 1 - 8thWelcome to 910 Ocean Boulevard! This oceanfront getaway has something for the entire family. Choose your favorite spot from multiple oceanfront decks...

  • Isle of Palms
  • 5 Bedrooms
  • 4 Bathrooms
  • Sleeps 12