Charleston-SC.com logo

Isle of Palms, SC 2+ Bedroom Vacation Rentals

Filter 2+ Bedroom Isle of Palms Properties by: Company | Oceanfront | Pet-Friendly | or choose different a Area or Bedrooms
No company options available.
Bedrooms:
332 rentals found
NEW LISTING! 501 MOORINGS, Fully renovat...

NEW LISTING in Wild Dunes! 501 MOORINGS, Entirely remodeled condo, Marina View, Community Pool, and Elevator. Ideal Location for Family, or 4 adult Boaters, Golfers, or Fishermen. Located within feet of the marina and community pool, accepting...

  • Isle of Palms
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 6
Screen porch, Golf Cart, Pet friendly, L...

All new reservation (3-21 nights) will receive $250 credit toward beach gear units with VayK Life!Charming Island home with hot tub! Unwind in the living room with flat-screen TV, den, and 2 front verandas, all with ample seating. Totally supplied...

  • Isle of Palms
  • 4 Bedrooms
  • 3 Bathrooms
  • Sleeps 8
Golf View, Pool, Pickleball, Stocked kit...

Elegantly refreshed townhome on the 6th green of the Links Course in Wild Dunes Resort. This 1180 sqft vacation home offers marvelous vistas of the approaching shots on the 6th green links course. Totally modernized from floor to ceiling with new...

  • Isle of Palms
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 6
Spacious Beach Home w/Boat Parking! Easy...

Your Isle of Palms Dream Home is Waiting! Property HighlightsBoat Parking - Steps to the Isle of Palms MarinaExtensive Porch - Partially Screened InGolf Course VistasTwo Living Areas - One with a Pool Table$250 Beach Gear Credit with 3-14 nighttime...

  • Isle of Palms
  • 5 Bedrooms
  • 4 Bathrooms
  • Sleeps 10
Upscale Oceanfront Home + Private Pool +...

The Layne House – Oceanfront Luxury on Isle of PalmsStep into The Layne House, an exclusive 4-bedroom, 4.5-bathroom oceanfront getaway where nearly every room captures sweeping vistas of the Atlantic. From morning coffee on the deck to sunset...

  • Isle of Palms
  • 4 Bedrooms
  • 4 Bathrooms
  • Sleeps 10
Discounts! OCEANFRONT STUNNER- Discounte...

**Ask about our current discounts for Summer 2025!Tired of looking through tons of listings? Do you need a specific type of home or dates? We are a local family owned company, Exclusive Properties, located right here on Isle of Palms. We specialize...

  • Isle of Palms
  • 7 Bedrooms
  • 6 Bathrooms
  • Sleeps 12
29 24th Avenue by AvantStay | Easy Beach...

Gather your family together and treat them to a dream vacation at 29 on 24th Avenue on the Isle of Palms. This four-bedroom, three bath home has the amenities that will make everybody’s dreams come true. The kids will run straight to the new pool...

  • Isle of Palms
  • 4 Bedrooms
  • 3 Bathrooms
  • Sleeps 10
Whispering Palms- The Perfect Beach Hous...

-- Description --As part of our Island Collection, 8 31st Ave is a beautiful beach home you won't forget. Located just one short block from the ocean, you can effortlessly hop on the beach path at the end of the street. Savor spending beach time...

  • Isle of Palms
  • 5 Bedrooms
  • 4 Bathrooms
  • Sleeps 10
Beachwood East 19 by Wild Dunes, Ocean V...

Beachwood East 19 by Wild Dunes7 Bedroom | 7 Bathroom | Sleeps 16 | Oceanfront _____________________________________Welcome to Beachwood East 19, a impressive getaway on Isle of Palms’ exclusive Wild Dunes Resort. Feel island living in this...

  • Isle of Palms
  • 7 Bedrooms
  • 6 Bathrooms
  • Sleeps 16
712 Ocean Blvd | New Build + Pool, Game ...

Sun, sand, and wellness collide at Stay Salty—a brand-new, oceanfront getaway on Isle of Palms where modern luxury meets intentional, healthy living. With six bedrooms (including 5 California King beds), six full bathrooms, and a powder room, this...

  • Isle of Palms
  • 6 Bedrooms
  • 7 Bathrooms
  • Sleeps 12
415 B Shipwatch by AvantStay | Oceanfron...

Be prepared to be pampered because this handsome condominium has anticipated your every expectation. Featuring three bedrooms and three full baths, 415 B Shipwatch is ideally located; on the oceanfront on the best stretch of beach in Wild Dunes. A...

  • Isle of Palms
  • 3 Bedrooms
  • 3 Bathrooms
  • Sleeps 6
Gated Ocean Point Home, 4BR, End Unit, P...

Welcome to 30 Ocean Point Drive — your ideal coastal hideaway inside the peaceful, gated Ocean Point neighborhood of Wild Dunes Resort on the Isle of Palms. This handsome 4-bedroom, 4-bath corner lot home sits just steps from the beach and offers...

  • Isle of Palms
  • 4 Bedrooms
  • 4 Bathrooms
  • Sleeps 8
28 Pelican Bay! Wild Dunes Family Vacati...

Welcome to your ideal coastal getaway at 28 Pelican Bay! This impressive and inviting 4-bedroom beach home is located in a peaceful, oceanside neighborhood, just a leisurely 3–4 min. walk from the pristine shoreline. Ideal for families, this home...

  • Isle of Palms
  • 4 Bedrooms
  • 3 Bathrooms
  • Sleeps 8
Oceanfront! Pool, Hot Tub, Walk to Town,...

Monthly Winter Rental Pricing, stays 28+ nights, please inquire! Welcome to 910 Ocean Boulevard! This oceanfront getaway has something for the entire family. Choose your favorite spot from multiple oceanfront decks, poolside, calming in the hot tub...

  • Isle of Palms
  • 5 Bedrooms
  • 4 Bathrooms
  • Sleeps 12
Swim Spa, Tiki Bar, Pet friendly, Fenced...

Welcome to your vacation at the Blue House! This 4 bed, 3 bath home is freshly refreshed with all updated bathrooms and kitchen upgrades. Appreciate a short 2 min. walk to the beach, as this home is located just 3 homes back. A brand new Hot Tub has...

  • Isle of Palms
  • 4 Bedrooms
  • 3 Bathrooms
  • Sleeps 8
Upgraded SEAGROVE Villa!  Beachside, Des...

Feel the beauty and serenity in this newly refreshed Seagrove Villa. Wild Dunes has it all. From the striking beaches to the world-class golf, there is no shortage of exceptional natural beauty. There is no place better to spend your next vacation...

  • Isle of Palms
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 6
322 D Shipwatch by AvantStay | Community...

322 D Shipwatch is the ideal Isle of Palms vacation hideaway. This 2 bedroom 2 bath unit complete with an oceanfront balcony makes this an memorable time to gather with family or friends.What is really spectacular about 322 D Shipwatch is the...

  • Isle of Palms
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 6
Twin Oaks 26 by Wild Dunes, with Golf Vi...

Twin Oaks 26 by Wild Dunes3 Bedrooms | 2 Bathrooms | Sleeps 6 | Resort View________________________________________Twin Oaks enjoys a prime setting just moments from striking stores, gourmet eateries, and the energetic center of the resort. Designed...

  • Isle of Palms
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 6