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Charleston, SC 2+ Bedroom Vacation Rentals

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1053 rentals found
A1 at Saint Philip Square, One Block to ...

Welcome to Saint Philip Square, an award-winning collection of historic homes spanning nearly one city block in downtown Charleston. The John Bulow House at 174 A Saint Philip Street Unit 1 is a 3-bed 3-bath gem blending modern comfort with...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 8
Retreat Near the Charleston Greenway-Wat...

Roomy and family-friendly getaway ideally located near the Charleston Greenway with peaceful tidal water vistas. This 4-bedroom, 2.5-bath home offers plenty of room for groups of all sizes, featuring three bedrooms with comfortable queen beds and a...

  • Charleston
  • 4 Bedrooms
  • 3 Bathrooms
  • Sleeps 9
8B at Saint Philip Square, One Block to ...

Welcome to Saint Philip Square, an award-winning collection of historic homes spanning nearly one city block of downtown Charleston. The Alexander Wilson House at 178 Unit B Saint Philip St. is a 2-bed 2-bath gem blending modern comfort with...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 6
Private Renovated 2BR Charleston Townhom...

Minimum Stay: 30 DaysThis freshly modernized two-bedroom, two-bath townhome offers a comfortable and private setting for extended stays in Charleston. Located in a peaceful community just mins. from downtown, MUSC, and local beaches, it provides the...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 5
Liberty Place Charleston, a Hilton Club ...

*** Sanitation/Cleaning Update ***We understand that our guests’ expectations for hotel cleaning and disinfecting have changed. That’s why we’ve taken additional measures beyond our industry-leading cleaning standards by partnering with RB...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 6
Spacious 3-bedroom apartment off King St...

Your Charleston adventure begins at this 3-bedroom apartment. Inside, guests find two king beds and one queen bed, offering plenty of space for a restful nighttime. Whether you’re calming indoors or planning your day, the ideal blend of comfort...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 6
8 Bedroom - Newly Renovated - Parking & ...

Feel the timeless appeal of Charleston’s historic peninsula, the Holy City. Stay just mins. from MUSC, the College of Charleston, and the vibrant shopping, dining, and nightlife of King Street. From this ideally located downtown home, you’ll be...

  • Charleston
  • 8 Bedrooms
  • 6 Bathrooms
  • Sleeps 16
Where Tranquility Blooms | Blossoms on C...

Permit Number: 06351The Space: Welcome to Blossoms on Cannon, a elegantly restored two-story Charleston home designed for comfort, connection, and memorable group stays. With 5 bedrooms and 4 bathrooms, this roomy getaway is ideal for up to 10...

  • Charleston
  • 5 Bedrooms
  • 4 Bathrooms
  • Sleeps 10
The Chapel | Premier 13BR Estate in Down...

Summary:Welcome to The Chapel, a majestic 13-bedroom estate in downtown Charleston where beauty, space and heritage combine to create an memorable stay. Ideal for sizable families, weddings, get-togethers or special gatherings, this property offers...

  • Charleston
  • 13 Bedrooms
  • 12 Bathrooms
  • Sleeps 16
Hot Tub Getaway • Parking • 1 Block ...

Summary:✨ Welcome to The Palms of Charleston Penthouse! ????☀️ Generous Courtyard with Hot Tub???? 1 Block to King St – Walk to Charleston’s Finest Dining, Shopping & Nightlife???? Balcony with Seating???? Off-Site Parking for 2...

  • Charleston
  • 4 Bedrooms
  • 2 Bathrooms
  • Sleeps 8
Manor House Suite in Historic Cannonboro...

Summary:The Kiawah Suite features a handsome three queen bedrooms and two baths, as well as a full kitchen and living space. Located on the 1st floor of a historic Charleston home constructed in the late 1800s, this suite overlooks Cannon Street's...

  • Charleston
  • 3 Bedrooms
  • 3 Bathrooms
  • Sleeps 6
NEW! Close To Downtown Charleston And Be...

Come experience Charleston while staying in this ideally styled new build. 4 miles to Downtown Charleston with award winning eateries, extraordinary nighttime life, and historic beauty. Centrally located to Folly Beach and Sullivans Island Beach...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 6
Charming 4-bedroom home, 10 Minutes to D...

Totally refreshed in 2025 -- Stay comfortably in Charleston at this 4-bedroom home. Each bedroom features a king bed, ensuring a pleasant nighttime's sleep for all guests. With amenities like a washing machine, WiFi, and AC, your stay will be both...

  • Charleston
  • 4 Bedrooms
  • 4 Bathrooms
  • Sleeps 8
Hot Tub • Private Courtyard • 1 Bloc...

Summary:✨ Welcome to The Palms of Charleston! ????☀️ Enormous Private Courtyard with Hot Tub???? 1 Block to King St! Walk to Charleston’s Finest Dining, Shopping & Nightlife???? Ideal for Sizable Groups – Families, Wedding Guests...

  • Charleston
  • 7 Bedrooms
  • 4 Bathrooms
  • Sleeps 14
The Saint | Newly Built Charleston Home ...

Summary:Welcome to The Saint, a freshly constructed Charleston home that showcases striking architectural design and modern comfort in a walkable urban setting. Ideal for families, friends, or style-conscious travelers who appreciate light-filled...

  • Charleston
  • 4 Bedrooms
  • 3 Bathrooms
  • Sleeps 12
Thomas Waring House | Sleeps 23 | Multi-...

Summary:Welcome to the Thomas Waring House at The Preserve, a historic and award-winning residence that offers a unique blend of appeal and modern convenience. Comprising 4 separate units, this broad property features a total of 11 bedrooms and 11.5...

  • Charleston
  • 11 Bedrooms
  • 11 Bathrooms
  • Sleeps 23
New Condo Nestled in Historic Downtown C...

Come savor this brand new rental in the heart of Downtown Charleston. Completed in July of 2018, these units offer something that most downtown units cannot. Stocked with a full kitchen and linens, you can`t beat what this rental has to offer! Ideal...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 6
Picture Perfect Charleston Living on Spr...

This isn't just a stay; it's an invitation to the best of Spring Street. Whether you’re grabbing a coffee at Bad Bunnies or exploring the stores of Upper King, everything is within a few mins.' walk. After exploring, getaway to your gated...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 5