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Charleston, SC 2+ Bedroom Vacation Rentals

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1049 rentals found
End of Summer Deal - Designer 2BR Histor...

Charming 2-Bedroom Retreat with Modern ComfortsWelcome to your Charleston home away from home. This elegantly decorated 2-bedroom, 1-bath historic condo offers bright natural light, thoughtful design, and two private balconies ideal for appreciating...

  • Charleston
  • 2 Bedrooms
  • 1 Bathrooms
  • Sleeps 4
Downtown 3BR with New Private Plunge Poo...

Summary:Ideal for a huge family! Just three blocks away from upper King Street. Very close to MUSC. Our phenomenal cultural city also offers galleries, museums, beautiful churches, carriage tours, great shopping, and the beach is just 15 mins. away...

  • Charleston
  • 3 Bedrooms
  • 3 Bathrooms
  • Sleeps 8
Blissful Escape | Tranquility in Style (...

Permit Number: 06657The Space: Welcome to The Simonton Suite, a roomy Charleston getaway just off Spring Street and steps from neighborhood favorites like Bramble. Ideal for groups of up to six guests, this inviting condo blends historic appeal with...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 6
Casa Bella - Your Oasis in the Heart of ...

Permit Number: 05934The Space: Welcome to Casa Bella, a gorgeously refreshed Charleston getaway offering space, style, and historic appeal in the heart of downtown. Ideal for enormous groups of up to 11 guests, this unique property includes two...

  • Charleston
  • 6 Bedrooms
  • 4 Bathrooms
  • Sleeps 11
A1 at Saint Philip Square, One Block to ...

Welcome to appealing Saint Philip Square, a esteemed collection of 6 historic homes spanning nearly a city block of downtown Charleston. The John Bulow House at 174 Unit A#1 Saint Philip St. is a classic 3BD/3BA unit blending modern amenities and...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 8
The Lazy Susan

Discover this gorgeous 2-bedroom gem in Charleston. This beautiful apartment features a welcoming ambiance that will make guests feel right at home. With 1 queen bed and 1 full bed, a comfortable nighttime's sleep is guaranteed. The bathroom...

  • Charleston
  • 2 Bedrooms
  • 1 Bathrooms
  • Sleeps 4
Spacious, Private 3BR Suite: Steps to Ki...

Summary:The Kiawah Suite features a gorgeous three queen bedrooms and two baths, as well as a full kitchen and living space. Located on the 1st floor of a historic Charleston home constructed in the late 1800s, this suite overlooks Cannon Street's...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 6
Coastal Charleston Retreat Near Folly Be...

Extended-Stay Retreat on James Island | Dog-Friendly Home Near Charleston | Your Cozy Home Away From HomeEscape to the appeal of James Island and savor a calming extended stay in this chic, family-friendly home just mins. from downtown Charleston...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 6
Elegant Historic Queen St House.

Summary:Feel the appeal of Charleston in this charmingly restored historic home, ideally located in the heart of downtown on iconic Queen Street. Constructed in 1878 and thoughtfully remodeled, this extravagant property combines timeless Southern...

  • Charleston
  • 3 Bedrooms
  • 3 Bathrooms
  • Sleeps 6
Downtown - Near Historic Cigar Factory w...

Welcome to the Holy City, and the historic southern appeal of the Charleston peninsula. Our vacation rental is located in gorgeous downtown Charleston and just mins. away from MUSC, the College of Charleston, and King Street’s shopping and...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 8
Beautiful Art Villa in Historic Charlest...

Summary:Set on the upper floor of a elegantly modernized 1885 Charleston single, this 2-bedroom suite feels like living in the city, not just visiting it. The space is bright and open with a mid-century modern feel, two queen bedrooms, two private...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 4
2 Bedroom Condo, Sleeps 6, Lodge Alley I...

Take a step back in time with a stay at The Lodge Alley Inn in the heart of old Charleston, the cultural capital of the South, where layers of history await your discovery. The resort is actually a collection of 18th century warehouses that have...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 6
St. Tropez House | Historic 2-Story w/ C...

Summary:Welcome to St. Tropez House, a attractively preserved two-story home that exudes appeal, history, and grace. Located in Charleston’s heart, this home is ideal for guests who savor classic architectural details, serene outdoor spaces, and a...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 8
Edisto & Cooper House | Sleeps 14 | Full...

Summary:Book the whole home and bring everybody! Both floors are yours, with room for fourteen, an simple fit for bachelorette weekends, big birthdays, or the reunion that's been a long time coming. It's two full units, so between two kitchens and...

  • Charleston
  • 4 Bedrooms
  • 4 Bathrooms
  • Sleeps 14
Clean, Beachy, Amazing Waterview 
Near F...

Condo on the top floor with spectacular marsh vistas. Only 1 mile from the Folly Beach, shopping and eateries and 10 miles from Downtown Charleston. Bicycle lane in each direction from the condo to Folly Beach or the grocery store. Across the street...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 4
The Manor 93 A&B - 2 Newly Renovated Uni...

Welcome to 93 Spring Street, a charmingly restored 1880's Charleston home that combines historic appeal with modern amenities. Located just two and a half blocks from King Street, this cavernous home has been thoughtfully divided into two separate...

  • Charleston
  • 7 Bedrooms
  • 7 Bathrooms
  • Sleeps 14
8C at Saint Philip Square, One Block to ...

Welcome to appealing Saint Philip Square, a esteemed collection of 6 historic homes spanning nearly a city block of downtown Charleston. The Alexander Wilson House at 178 Unit C Saint Philip St. is a beautiful 3BD/4BA upstairs unit blending modern...

  • Charleston
  • 3 Bedrooms
  • 4 Bathrooms
  • Sleeps 8
The Crescent Moon - Walk to King

Come savor this revamped 2 bedroom 2 bathroom apartment centrally located on the Charleston peninsula. Take a short walk to King Street to appreciate a meal at one of Charleston’s many world acclaimed eateries, or take advantage of the well...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 6