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Charleston, SC 2+ Bedroom Vacation Rentals

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1052 rentals found
Luxury Bungalow Steps Away From Trendy A...

Steps away from fun & trendy Avondale! Cook your own meals in the charming gourmet kitchen or walk to spectacular eateries, bars, breweries & shopping. The 8 mile Greenway running trail is just across the street. Quick 5 min. Uber ride to Downtown...

  • Charleston
  • 2 Bedrooms
  • 1 Bathrooms
  • Sleeps 6
Private & Quiet Retreat Near Folly Beach

Escape to your private & peaceful 2-bedroom getaway just mins. from the famed sandy shores of Folly Beach. This striking, detached guesthouse offers a peaceful getaway with its own entrance and parking. Inside, you’ll find a comfortable living...

  • Charleston
  • 2 Bedrooms
  • 1 Bathrooms
  • Sleeps 4
Charleston Charm - 3 Bedroom - 2 Blocks ...

Discover Charleston from this freshly refreshed 3-bed, 2-bath downtown home, just 2 blocks from King Street! Updated in 2024, this modren ground-floor unit comfortably sleeps 8 guests. Savor modern amenities, a completely equipped kitchen, a private...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 8
Casa Zoë: Bright Charleston Cottage Nea...

Summary:OP2025-05861Point of View Cottage is a bright and airy Casa Zoë getaway made from two seamlessly connected spaces - ideal for families, friends, or groups who want to stay together but still savor a bit of breathing room. With five...

  • Charleston
  • 5 Bedrooms
  • 4 Bathrooms
  • Sleeps 14
Folly Cottage - Pet Friendly

Vintage Beach Cottage – 2 miles from the Shore! 5 miles from Downtown Charleston! Pet Friendly!Welcome to this classic coastal hideaway with a touch of retro appeal! This older home offers a funky Folly vibe and unbeatable proximity to the beach...

  • Charleston
  • 3 Bedrooms
  • 1 Bathrooms
  • Sleeps 8
Private Renovated 2BR Charleston Townhom...

Minimum Stay: 30 DaysThis newly refreshed two-bedroom, two-bath townhome offers a comfortable and private setting for extended stays in Charleston. Located in a peaceful community just mins. from downtown, MUSC, and local beaches, it provides the...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 5
Rosemary House | Unit C | Sleeps 10

Summary:Welcome to the Rosemary House-Suite C at The Preserve, a roomy and elegantly appointed residence occupying the upper floors of a attractively preserved historic home. With 4 bedrooms and 5 bathrooms, this property offers ample privacy and...

  • Charleston
  • 4 Bedrooms
  • 5 Bathrooms
  • Sleeps 10
The Monroe | Award-Winning Renovated His...

Summary:Indulge in a stay at The Monroe on Spring. An entirely-modernized, Historic Charleston manor circa 1885. No expense was spared in the restoration, intended to exude both rich history and modern extravagance. Just a brief walk to the iconic...

  • Charleston
  • 3 Bedrooms
  • 3 Bathrooms
  • Sleeps 11
Charming 2-bedroom, 1.5 bath townhome in...

This furnished 2-story, 2-bedroom, 1.5 bathroom, end-unit townhome features 1,000 sq ft. of living space, wood floors, & high ceilings. This home offers an open layout & charmingly refreshed kitchen & dining! The kitchen features a stainless by...

  • Charleston
  • 2 Bedrooms
  • 1 Bathrooms
  • Sleeps 4
Retreat on King Street | Ashley Suite

Permit Number: 004141The Space: Discover The Ashley Suite, a comfortable second-floor unit in historic Charleston at 493 Luxury Suites. Appreciate a seamless blend of comfort and convenience in this chic getaway.Enter the roomy layout where the...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 6
French Quarter Escape – Walk to City M...

Maison Des Fleurs – Sophisticated Pied-à-Terre in Charleston's French QuarterTucked along beautiful Lodge Alley in the heart of Charleston's historic French Quarter, Maison Des Fleurs is a charmingly remodeled 2-bedroom, 1.5-bathroom getaway...

  • Charleston
  • 2 Bedrooms
  • 1 Bathrooms
  • Sleeps 4
Wonderful 3BDR Guest Suite Sits Between ...

Welcome to your calming getaway on James Island! Our 3br 1ba unit is located 4 miles from Folly Beach and 8 miles from downtown. You'll be able to savor all the benefits of both the city and the beach. This handsome home has a private main entrance...

  • Charleston
  • 3 Bedrooms
  • 1 Bathrooms
  • Sleeps 6
Beautifully renovated,  walkable home in...

8 mins. to downtown Charleston – this walkable, 3 bed/2 bath stunner, is close to everything. Right near 526, and a short drive to all local beaches! MUSC and Roper are close by as well. Moving and need an interim home; in town for work; just...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 9
The Charleston Suites: The Charles Suite

The Charles Suite:>> Prime Location: Ideal escape from busy streets>> Quick walk to drinks, dinner, and shopping>> 20 min drive to soak up the sun at 1 of 3 beaches>> Professionally Turfed Backyard w/ Pergola + Grille>> Beds for 4 Guests>> Private...

  • Charleston
  • 2 Bedrooms
  • 1 Bathrooms
  • Sleeps 4
Modernized 5BR Family Home?Tranquil Pati...

This pretty 5-bedroom, 2.5-bathroom home is a true gem, located on one of the quietest streets in Charleston. With freshly modernized bathrooms, resurfaced floors, and a cavernous, open floor plan, this home is ideal for families or professionals...

  • Charleston
  • 5 Bedrooms
  • 3 Bathrooms
  • Sleeps 10
Downtown Duplex - Rutledge Avenue

Feel the timeless appeal of Charleston’s historic peninsula, the Holy City. Stay just mins. from MUSC, the College of Charleston, and the vibrant shopping, dining, and nightlife of King Street. From this ideally located downtown home, you’ll be...

  • Charleston
  • 4 Bedrooms
  • 2 Bathrooms
  • Sleeps 12
The Oyster Suite | 2BR Steps to King Sle...

Summary:Welcome to The Oyster Suite, your cheerful home base in Charleston. This 2BR/2BA first-floor condo offers a thoughtfully equipped kitchen and inviting living spaces ideal for families or friends. Unwind after a day of exploring or stay in...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 4
Boho Haven in CHS | Southern Shangri-La ...

Permit Number: 06314The Space: Welcome to Southern Shangri-La on Coming, a tropical-inspired urban getaway tucked just off Coming Street in the heart of downtown Charleston!This second-floor apartment offers about 700 square feet of bright...

  • Charleston
  • 2 Bedrooms
  • 1 Bathrooms
  • Sleeps 4