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Charleston, SC 2+ Bedroom Vacation Rentals

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1059 rentals found
Casa Zoë | Grand Sparrow House

Summary:OP2026-07255OP2026-07256OP2026-07257Casa Zoë’s crown jewel, The James Sparrow House, is a huge Federal-style landmark reimagined for modern gatherings. Entirely redesigned, it blends 19th-century craftsmanship with bold interiors and...

  • Charleston
  • 9 Bedrooms
  • 7 Bathrooms
  • Sleeps 27
Newly Renovated, Historic 2bd/2ba Downto...

Spend the summer in downtown Charleston living in the heart of it all at this 28+ day rental!The 2 bedroom, 2 bathroom, 1200 sq ft home, originally constructed in the 1880s, was newly restored back to its former glory but refreshed to modern...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 8
King Street Condo - Endless Outdoor Spac...

Summary:Welcome to your Charleston getaway at King Street Condo – Endless Outdoor Space! This home is ideal for guests who appreciate indoor-outdoor living, room to stretch out, and walking access to the best stores and eateries King Street has to...

  • Charleston
  • 2 Bedrooms
  • 1 Bathrooms
  • Sleeps 5
Newly Renovated West Ashley Retreat, Nea...

This entirely furnished, freshly remodeled home is located in a peaceful, well-established West Ashley neighborhood, ideally positioned near all of Charleston’s top attractions. Guests appreciate a convenient 12-min. drive to Downtown Charleston...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 8
Charming Charleston Craftsman Bungalow

Incredibly striking, this 1930's home has been lovingly preserved to give an old Charleston feel. Featuring a enormous kitchen, screened porch, private, fenced-in back yard and shaded garden. Inside, a charming den and a constructed-in office nook...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 4
New 2-bedroom1 bath detached guest house...

Our new detached guest home is a cavernous 2 bedroom/1 bath rental located near some of the best areas of Charleston. The guest home is located just 7 mins. from the restaurant/bars, stores, and Atlantic Ocean of impressive Folly Beach and 15 mins...

  • Charleston
  • 2 Bedrooms
  • 1 Bathrooms
  • Sleeps 6
Cheerful 2BR Retreat - King Street Locat...

Summary:Welcome to your Charleston hideaway, a cheerful 2-bedroom home in an ideal spot just steps from King Street. Ideal for couples or modest groups who appreciate both lively city access and comfortable comfort, this getaway offers a private...

  • Charleston
  • 2 Bedrooms
  • 1 Bathrooms
  • Sleeps 6
Zuma Suite | Walk to King Street Shops!

Summary:Welcome to your fresh escape, a thoughtfully designed getaway that blends clean modern interiors with comfortable appeal. Ideal for couples, solo travelers or modest groups, this property offers comfort, convenience and access to the very...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 5
Charming 4-bedroom home, 10 Minutes to D...

Totally refreshed in 2025 -- Stay comfortably in Charleston at this 4-bedroom home. Each bedroom features a king bed, ensuring a pleasant nighttime's sleep for all guests. With amenities like a washing machine, WiFi, and AC, your stay will be both...

  • Charleston
  • 4 Bedrooms
  • 4 Bathrooms
  • Sleeps 8
The Charleston Suites: The Charles Suite

The Charles Suite:>> Prime Location: Ideal escape from busy streets>> Quick walk to drinks, dinner, and shopping>> 20 min drive to soak up the sun at 1 of 3 beaches>> Professionally Turfed Backyard w/ Pergola + Grille>> Beds for 4 Guests>> Private...

  • Charleston
  • 2 Bedrooms
  • 1 Bathrooms
  • Sleeps 4
Close to Beach and Downtown Charleston

Welcome to Casa de la Costa! Located in a family friendly, peaceful neighborhood this vacation home is centrally located just 2 miles from Folly Beach and 9 miles to downtown CharlestonThis home is ideal for your family vacation at the beach . It...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 6
Perfect Location - King Street Condo!

Summary:Welcome to your downtown Charleston escape, charmingly located just off King Street and offering both elevated vistas and shared outdoor spaces to soak up the city’s ambiance. Ideal for couples or modest groups who value comfort, design...

  • Charleston
  • 2 Bedrooms
  • 1 Bathrooms
  • Sleeps 5
The Charleston Suite: The Harper Suite

The Harper Suite:>> Prime Location: Ideal escape from busy streets>> Quick walk to drinks, dinner + shopping>> 20 min to 1 of 3 beaches>> Balcony w/ Bistro Set + Porch Swing>> Professionally Turfed Shared Backyard w/Pergola + Grille>> Beds for 6...

  • Charleston
  • 3 Bedrooms
  • 1 Bathrooms
  • Sleeps 6
The Charlestonian, Spacious, Luxury Suit...

Summary:The Kiawah Suite features a handsome three queen bedrooms and two baths, as well as a full kitchen and living space. Located on the 1st floor of a historic Charleston home constructed in the late 1800s, this suite overlooks Cannon Street's...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 6
Prime Home on King and Market | Marquee ...

Permit Number: 51196The Space: Welcome to The Marquee Suite B, a roomy third-floor condo located directly on historic King Street with off-street parking and simple access to Charleston’s best dining, shopping, and nightlife!This inviting getaway...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 7
Boutique Luxury Apt Marion Sq Downtown |...

Spanning more than 700 square feet, this bright and well-appointed apartment offers a refined stay for families, couples, or business travelers alike.Two serene king bedrooms, each equipped with ceiling fans and sound machines, promise a restful...

  • Charleston
  • 2 Bedrooms
  • 1 Bathrooms
  • Sleeps 4
Spring St - Downtown Charleston - Walk E...

Feel the timeless appeal of Charleston’s historic peninsula, the Holy City. Stay just mins. from MUSC, the College of Charleston, and the vibrant shopping, dining, and nightlife of King Street. From this ideally located downtown home, you’ll be...

  • Charleston
  • 4 Bedrooms
  • 4 Bathrooms
  • Sleeps 10
Beach Chic Meets Classic Charleston+Bike...

Nightly or Monthly* availability (* for 1-6 month stays, please message to inquire for options that may not reflect on calendar) . Stylishly refreshed 1950s Charmer offers Indoor/Outdoor Living in highly sought after Riverland Terrace of Charleston...

  • Charleston
  • 2 Bedrooms
  • 1 Bathrooms
  • Sleeps 5