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Charleston, SC 2+ Bedroom Vacation Rentals

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1055 rentals found
The Beat | 2BR in the Heart of Downtown ...

Summary:Welcome to your Charleston hideaway a beautiful 2-bedroom getaway rich in historic character and thoughtful modern touches. Ideal for solo travelers or couples who savor warmth style and architectural detail in a walkable location.The...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 5
Guesthouse Charleston: WEST (242 B)

West 242 B is a striking standalone home located in the heart of the Cannonborough/Elliotborough neighborhood, just two blocks from historic King Street. This prime downtown Charleston location offers simple access to the best eateries, coffee...

  • Charleston
  • 4 Bedrooms
  • 3 Bathrooms
  • Sleeps 8
The Crescent Moon - Walk to King

Come savor this revamped 2 bedroom 2 bathroom apartment centrally located on the Charleston peninsula. Take a short walk to King Street to appreciate a meal at one of Charleston’s many world acclaimed eateries, or take advantage of the well...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 6
PRIME + Rare Location, Restored 1800s Mo...

Summary:Stay in the heart of historic Charleston, just steps from Waterfront Park and the iconic Pineapple Fountain. This gorgeously restored 1800s building was refreshed in 2026 with modern interiors, original artwork, and thoughtful amenities...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 4
Crosstown @ King | Downtown Dream - Walk...

Summary:Stay in the heart of Charleston at this classy 3BR, 2BA home just a block from King Street. Ideal for families and groups, it features two king bedrooms, a queen bedroom, and flexible sleeping with an air bed. Appreciate luxury linens...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 7
Belle Haven Duplex - Downtown - New Reno...

Feel the timeless appeal of Charleston’s historic peninsula, the Holy City. Stay just mins. from MUSC, the College of Charleston, and the vibrant shopping, dining, and nightlife of King Street. From this ideally located downtown home, you’ll be...

  • Charleston
  • 4 Bedrooms
  • 2 Bathrooms
  • Sleeps 8
Cannon Collective | 5BR Historic Home Do...

Summary:Welcome to Cannon Collective, a cavernous 5 bedroom home in downtown Charleston full of character, elegance and prime access. Ideal for enormous groups, families or gatherings looking for comfort, appeal and space. You will find yourself...

  • Charleston
  • 5 Bedrooms
  • 4 Bathrooms
  • Sleeps 15
No Fee Fiesta: Pet Friendly, Close to Do...

No to-do lists here, just relax on the porch with the whole family (family pets too) at our marsh front home.You're in a great spot, no matter what you savor doing.A fast drive to downtown to indulge in Charleston's famed restaurant scene or jump in...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 8
Luxury, High-End w. Elevator, Parking + ...

Summary:Savor sleek living in this modern 4-bedroom unit at The Charlee. With elevator access, your own EV charger, and a BBQ grille for alfresco evenings, what more could you need. The clean lines and modern decor set the ideal backdrop for...

  • Charleston
  • 4 Bedrooms
  • 3 Bathrooms
  • Sleeps 10
The Suite  Carolinas

Parties are stringently prohibited at all of our properties. Additionally, serving alcohol to minors is not allowed under any circumstances.

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 6
Charming Charleston Coastal Cottage

Unwind in our roomy and calming Coastal Cottage. Centrally located, 20 mins. from beaches, downtown Charleston, 15 mins. to airport & 5 mins. from Daniel Island where there are walking trails, eateries, grocery store, and much more! Guests have...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 7
Luxury Boutique Hotel Vibes. More Space,...

Feel boutique luxury in the heart of downtown Charleston. At Concept House, every detail is curated—from locally sourced furnishings to serene, beautiful spaces that invite you to relax. Wake up in crisp linens, sip coffee in the private manicured...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 6
The Grand Helène - Newly Renovated 11BD...

Summary:Recently constructed 11BR/11.5BA home in the laid-back Cannonborough/Elliotborough neighborhood—ideal for enormous groups seeking space and privacy. The property features three separate units in one building, ideal for gathering together...

  • Charleston
  • 11 Bedrooms
  • 12 Bathrooms
  • Sleeps 22
Dianna Browns Place | Historic District

Permit Number: 06411The Space: Welcome to a attractively restored second floor apartment in the heart of Charleston’s historic French Quarter. Thoughtfully designed and rich in character, this cavernous two bedroom, two bathroom home blends modern...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 4
Plunge Pool|Downtown Oasis|Close to Bars...

Summary:Welcome to The Sullivan & Palm, a attractively restored Victorian home in the heart of downtown Charleston. This cavernous 5-bedroom getaway blends historic appeal with modern amenities, featuring classy living spaces, a chef’s kitchen...

  • Charleston
  • 5 Bedrooms
  • 3 Bathrooms
  • Sleeps 12
Chic downtown condo. Walk to everything!

Luxury Urban Loft with Stunning Park Vistas & Rooftop RetreatStep into modren city living with this cavernous 2-bedroom, 2-bathroom loft in an environmentally friendly, LEED Certified complex. This light-filled home features soaring 10-foot ceilings...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 5
Downtown Modern - 4BR Spring St. Home w/...

Welcome to the Holy City, and the historic southern appeal of the Charleston peninsula. Our Vacation Rental By Owner is located in handsome downtown Charleston and just mins. away from MUSC, the College of Charleston, and King Street’s shopping...

  • Charleston
  • 4 Bedrooms
  • 3 Bathrooms
  • Sleeps 11
Only 1 block to King! | The Sunsetter

Permit Number: 07047The Space: Step into the timeless appeal of a classic Charleston single home located at Saint Phillip and Morris Streets, just one block from King Street with eateries, stores, and nightlife right at your doorstep!This historic...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 7