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Charleston, SC 2+ Bedroom Vacation Rentals

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1070 rentals found
Charming 2-bedroom condo, Folly Beach

Welcome to our striking two-bedroom condo located in the heart of Folly Beach. This inviting vacation rental offers a ideal blend of coastal appeal, modern comfort, and convenience. With its prime location just steps away from the beach and...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 4
The Juliette - Historic Luxury Residence

Our upstairs flat suitably located in the heart of Downtown Charleston, it is our honor to introduce The Juliette. Prioritizing an opulent aesthetic with comfort in mind, it is here that you'll find the mastery of accommodation at last. All...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 8
EAST 46 G - 1 Block to King!

Located just one block off King Street in the beautiful Cannonborough/Elliotborough neighborhood, East 46 - G is a bright and roomy second-floor apartment offering the ideal combination of comfort and style. You'll be close to local eateries...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 6
Charleston Villa | 6bd, Designer Downtow...

Summary:Welcome to your Charleston escape where roomy living meets fresh design. This six bedroom home is ideal for huge groups or families looking for comfort, modern amenities, and an inviting patio for gathering. You will savor privacy, elegance...

  • Charleston
  • 6 Bedrooms
  • 3 Bathrooms
  • Sleeps 16
Fit & Coasty - 2bd w/ Firepit, Workspace...

Welcome to Fit & Coasty in pretty West Ashley! Our home is ideal for any size group or those traveling for work for 30+ days! Our home is completely equipped with everything you need for a comfortable stay, including a entirely outfitted kitchen...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 4
Oikos - 19 Bedrooms in Downtown Charlest...

Permit Number: 06280The Space: After February 2026, appreciate a brand-new opulent pool in the enclosed backyard. Photos coming soon!Welcome to your ultimate group hideaway! This broad 4-unit, 19-bedroom listing is ideal for sizable groups...

  • Charleston
  • 19 Bedrooms
  • 15 Bathrooms
  • Sleeps 38
The Jacob Rabb House -Steps to the Histo...

Summary:The Jacob Rabb House (circa 1851) is located in the exclusive Ansonborough neighborhood in the heart of the Historic District. Its location presents a walkable opportunity to experience Charleston, while also providing 3 off-street parking...

  • Charleston
  • 4 Bedrooms
  • 3 Bathrooms
  • Sleeps 8
The Sunrise | 3BR Down - Best of Charles...

Summary:Welcome to The Sunrise, a 3-bedroom home newly modernized to combine fresh comfort, classic appeal, and unbeatable proximity downtown. Ideal for travelers who want classy space, modern updates, and everything Charleston has in store just...

  • Charleston
  • 3 Bedrooms
  • 3 Bathrooms
  • Sleeps 8
Hotel Richemont Brickell Suite 202

Charming 2-Bedroom Retreat in the Heart of CharlestonWelcome to your ideal Charleston hideaway! This elegantly appointed 2-bedroom home offers the ideal blend of comfort, style, and Southern appeal—just mins. from the city's historic district, top...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 4
Stunning Coastal Home w/ Spacious Yard &...

Make memorable memories in our freshly remodeled home! Imagine epic group hangouts in the backyard, with an outdoor eating area ideal for snacks and laughs. The kiddos get their own fun zone in the second living room with games and foosball! And the...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 9
Guesthouse Charleston: WEST (242 C)

West 242 C is a beautiful standalone home located in the heart of the Cannonborough/Elliotborough neighborhood, just two blocks from historic King Street. This prime downtown Charleston location offers painless access to the best eateries, coffee...

  • Charleston
  • 4 Bedrooms
  • 3 Bathrooms
  • Sleeps 8
Dream Charleston Getaway Perfect for Lar...

Welcome to your ultimate group-friendly Charleston getaway—a cavernous, impressive, and attractively refreshed property located just mins. from the heart of historic downtown. Designed with gatherings in mind, this unique setup features three...

  • Charleston
  • 4 Bedrooms
  • 3 Bathrooms
  • Sleeps 8
The Globetrotter | A Locals Hotspot

Permit Number: 05139The Space: Our cavernous 1st & 2nd floor home, ‘The Globetrotter House’, is ideal for groups of 8-11 guests with 4 bedrooms, and 4 full baths. Located just off Spring Street, location and parking won't be an issue...

  • Charleston
  • 4 Bedrooms
  • 4 Bathrooms
  • Sleeps 9
West 66 C - Freshly Renovated Upstairs 2...

Perched above the corner of Spring and Coming Street, West 66C is a light-filled getaway in the heart of Charleston s Cannonborough-Elliotborough neighborhood. This upper-level 2-bedroom, 2-bath home pairs thoughtful design with modern comfort ideal...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 4
Guesthouse Charleston: SOUTH (82 A)

82 - A is located on the first floor of a gorgeous standalone home, offering a roomy four-bedroom, four-and-a-half-bathroom apartment ideal for a weekend hideaway. Step inside to find an inviting open living, dining, and kitchen area, ideal for...

  • Charleston
  • 4 Bedrooms
  • 4 Bathrooms
  • Sleeps 8
? Walk Score 98 ? 1blk to King St. Outdo...

Summary:Welcome to your Charleston gathering spot, a cavernous 6-bedroom home constructed for sizable groups seeking style, flexibility, and unbeatable walkability. Featuring two high end kitchens, generous living spaces, and just one block from...

  • Charleston
  • 6 Bedrooms
  • 5 Bathrooms
  • Sleeps 16
High Society | Historic District Gem Nea...

Summary:Feel High Society in this handsome 4-bedroom, 3-bath home in Charleston’s Historic District. Unwind on private balconies with city vistas and appreciate the rare perk of off-street parking for four. Just blocks from King Street and the...

  • Charleston
  • 6 Bedrooms
  • 4 Bathrooms
  • Sleeps 12
The Charlee Flats | Luxury 4BR Retreat, ...

Summary:Stay at The Charlee on Cannon, a brand-new 4BR, 3BA condo blending modern luxury with Charleston appeal. Appreciate a roomy open-concept living area, private balcony, rooftop seating, and rare ADA accessibility with elevator access. Features...

  • Charleston
  • 4 Bedrooms
  • 3 Bathrooms
  • Sleeps 10