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Charleston, SC 2+ Bedroom Vacation Rentals

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1068 rentals found
Luxury Two Bedroom Residence with Outdoo...

The Pinch Hotel offers completely outfitted guestrooms, luxury amenities from check-in to check-out, and an ambiance of warmth and surprise, The Pinch is a touch of high culture in the Lowcountry. Let us redefine what a luxury, boutique hotel can...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 4
The Pearl Suite | 3BR 1st Floor Near Kin...

Summary:Welcome to The Pearl Suite, a serene 3BR 2BA home ideal for families or groups. Designed with calming sage tones and thoughtful touches, the home offers a warm and calming escape. Savor a entirely equipped kitchen for home-cooked meals and...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 6
Courtyard Cottage | Casa Zoë

Summary:OP2025-05860Courtyard Cottage pairs historic appeal with Casa Zoë’s signature style. Tucked just off the street, it offers two well-appointed bedrooms, a full bath, and a private brick courtyard made for morning coffee or late-nighttime...

  • Charleston
  • 2 Bedrooms
  • 1 Bathrooms
  • Sleeps 6
Charleston Villa | 6bd, Designer Downtow...

Summary:Welcome to your Charleston escape where roomy living meets modren design. This six bedroom home is ideal for sizable groups or families looking for comfort, modern amenities, and an inviting patio for gathering. You will appreciate privacy...

  • Charleston
  • 6 Bedrooms
  • 3 Bathrooms
  • Sleeps 16
Charming 2BR Historic Kitchen House Step...

The Sottile-Glover Kitchen House is in the heart of Charleston’s historic district. Simple walking distance to stores and eateries on King Street, City Market, Colonial Lake, CofC, Museums, and Art Galleries. It is also listed on the National...

  • Charleston
  • 2 Bedrooms
  • 1 Bathrooms
  • Sleeps 4
Newly Renovated West Ashley Retreat, Nea...

This completely furnished, freshly modernized home is located in a peaceful, well-established West Ashley neighborhood, ideally positioned near all of Charleston’s top attractions. Guests savor a convenient 12-min. drive to Downtown Charleston and...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 8
Stylish 5BR/5BA Downtown Retreat - Walk ...

Summary:Stay in this newly remodeled 5-bedroom, 5-bathroom downtown getaway accommodating up to 12 guests. Featuring open concept living areas, a entirely equipped kitchen, extravagant king beds, and off-street parking. Just one block from King...

  • Charleston
  • 5 Bedrooms
  • 5 Bathrooms
  • Sleeps 12
Right Where You Need to Be! Centrally lo...

You can stop searching, this is the one! 3 Bedroom open concept home in the ideal location on James Island. 10 mins. to downtown Charleston, 10 mins. to Folly Beach and 30 mins. to the Airport. We have a sizable patio to savor your morning coffee...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 6
6A at Saint Philip Square, One Block to ...

Come experience a luxury stay in the heart of Charleston at Saint Philip Square. Our award-winning collection of historic homes spans nearly one city block, The Aiken House, a 3-bed 3.5-bath gem that blends modern comfort with Charleston`s rich...

  • Charleston
  • 3 Bedrooms
  • 3 Bathrooms
  • Sleeps 8
James Island Airstream- Between Downtown...

Our freshly refreshed vintage 1976 Airstream Land Yacht is a comfortable Glamper that has everything you'd need for a cozy stay. Located next to our creek, you'll see water fowl galore while sipping your morning coffee in our outdoor seating area...

  • Charleston
  • 2 Bedrooms
  • 1 Bathrooms
  • Sleeps 4
Historic 1850s Home in Heart of Downtown...

Everyone loves our 1850's home located in the "Old City Historic District" of downtown Charleston. Its located less than a 10-min. walk to the center of the King Street and walking distance to the College Of Charleston, MUSC / Roper Hospital...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 7
The Inns | Renovated 2bd with Luxury Upg...

Summary:Tucked along striking Spring Street, this freshly remodeled 2-bedroom, 2-bath getaway captures the essence of Charleston appeal. Fresh paint, plush new linens, and handsome touches bring a sense of modern comfort to this timeless home...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 4
The Tree Top Terrace- is private, close ...

Located at 1545 Grimball Rd Ext, James Island, SC. This roomy Home has serenity & unique kind of privacy which places you in the middle of everything and yet above, it all. It's 5 mins. from Folly Beach with Island life and only 15 mins. from...

  • Charleston
  • 2 Bedrooms
  • 1 Bathrooms
  • Sleeps 6
‘Tropical Blue’ – Historic Home 5 ...

Summary:'The Tropical Blue' at The Blue Haven is a 5 min. walk to famed King Street. This refreshed historic home includes a modern kitchen, beautiful living area, and a traditional private piazza to lounge in the shade & watch the city go by.The...

  • Charleston
  • 4 Bedrooms
  • 4 Bathrooms
  • Sleeps 10
Queen Kelsey - mins from Credit One - pe...

Master Bedroom: 1 King BedGuest Bedroom: 2 Full Beds, 1 Bunk Bed with 2 twinsPack and Play included*Please Note: We operate our homes like a luxury hotel, just check in with a code and leave your towels on the floor when you check out. We take care...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 8
Tranquil Oasis | Blocks to King! | The H...

Permit Number: OP2025-06422 06423The Space: Welcome to The Hideaway; a striking downtown getaway made up of two private studio apartments on Spring Street, just 3 blocks from King Street in the heart of Elliotborough–Cannonborough!Ideal for...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 4
Walk to everything, upper king street ar...

This upstairs condo is located one block from historic Upper King shopping and dining district, and one block from C of C. Recently remodeled, the condo is bright and very comfortable for one or two couples. Features include queen sized beds...

  • Charleston
  • 2 Bedrooms
  • 1 Bathrooms
  • Sleeps 4
Newly Renovated close to Downtown & Foll...

Totally modernized in January 2022, Highland Cottage offers the ideal location in laid-back James Island, a suburb of Downtown Charleston. Ideally located 4 miles from Historic Downtown Charleston and 7 miles from Folly Beach. The bungalow is...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 4