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Charleston, SC 2+ Bedroom Vacation Rentals

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1055 rentals found
Designer Chic 6BR Full Downtown Charlest...

Feel the timeless appeal of Charleston’s historic peninsula, the Holy City. Stay just mins. from MUSC, the College of Charleston, and the vibrant shopping, dining, and nightlife of King Street. From this ideally located downtown home, you’ll be...

  • Charleston
  • 6 Bedrooms
  • 4 Bathrooms
  • Sleeps 14
Charleston Charm~B is 4 miles to Downtow...

This beautiful property is only 4 miles from Downtown Charleston! And centrally located to all of Charleston w/15-20 mins to all surrounding areas. 30 Day Minimum Stay. Within walking distance to some of Charleston local's favorite eateries. This...

  • Charleston
  • 2 Bedrooms
  • 1 Bathrooms
  • Sleeps 4
Spacious 4bd House, New Bathrooms, Near ...

Summary:Feel elevated Charleston living at Emerald Square, a freshly constructed private getaway in the heart of downtown. This sophisticated 4-bedroom, 3.5-bath residence pairs timeless Lowcountry style with modern elegance. Designed for gathering...

  • Charleston
  • 4 Bedrooms
  • 3 Bathrooms
  • Sleeps 10
Home Away From Home- Walkable, Parking &...

Keep it simple and peaceful at this beautiful centrally-located place.Welcome to your Charleston home base! This bright and roomy 2 bed, 1 bath upstairs apartment features a sizable open living area—ideal for calming, hanging with friends, or...

  • Charleston
  • 2 Bedrooms
  • 1 Bathrooms
  • Sleeps 4
Beautiful Art Villa in Historic Charlest...

Summary:Set on the upper floor of a elegantly remodeled 1885 Charleston single, this 2-bedroom suite feels like living in the city, not just visiting it. The space is bright and open with a mid-century modern feel, two queen bedrooms, two private...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 4
Pinkadilly on Spring! Walk to King St|Po...

Welcome to The Bloom Collective - a locally owned and female operated boutique hospitality experience. We are committed to creating a curated, thoughtful stay where every detail is designed to make your visit to Charleston as striking and memorable...

  • Charleston
  • 2 Bedrooms
  • 1 Bathrooms
  • Sleeps 4
Beautifully Restored  Downtown Apartment

Summary:The Jonathan J. Wright Inn is located in Charleston's striking historic Cannonborough-Elliotborough district. This traditional, Charleston-single home is conveniently located near top-rated eateries, nightlife, shopping, historical sites...

  • Charleston
  • 2 Bedrooms
  • 1 Bathrooms
  • Sleeps 4
AWESOME PROPERTY, GREAT DOWNTOWN CHARLES...

Our property is a legally allowed vacation rental as required by Charleston City ordinance. Our certificate of operational number is OP2025-06801One block from the heart of the entertainment district of Upper King Street. You will know you are in...

  • Charleston
  • 4 Bedrooms
  • 2 Bathrooms
  • Sleeps 10
Game Room• Fireplace • Backyard Deck...

Welcome to Your Storybook Hideaway * 16 miles to Historic Downtown Charleston* 25 miles to Folly Beach and Isle of Palm* 6.4 miles to Charleston International Airport* Free Wi-Fi and self-check-in* Free parking available* Fireplace* Entirely...

  • Charleston
  • 4 Bedrooms
  • 2 Bathrooms
  • Sleeps 10
Luxurious 4BR Downtown Home - Walkable!

Summary:This 4BR/4BA Charleston getaway offers en suite baths in every bedroom, modern finishes, and a entirely equipped kitchen. Appreciate a roomy first-floor layout, Intelligent TVs, and high-speed WiFi. Unwind with luxury linens, private outdoor...

  • Charleston
  • 4 Bedrooms
  • 4 Bathrooms
  • Sleeps 9
NY Times Featured Charming Home | Tully ...

Permit Number: 06858The Space: Welcome to Tully Alley, a really unique Charleston getaway where historic appeal meets modern comfort, featured in major publications including The New York Times, and offering an memorable stay in the heart of the...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 6
Historic Boutique Home ‘Nantucket’

Summary:A short walk from King St. 'The Nantucket' is a cavernous private historic property. The property offers a bright & open kitchen & living area, along with traditional southern piazza. Plenty of space for guests to relax. Property amenities...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 6
Historic Home with Large Porch + Palm Tr...

Summary:Welcome to Sweetgrass House, a delightfully preserved home with warm character, classic architecture, and a welcoming porch ideal for calming. Ideal for guests who appreciate being close to everything yet appreciate tranquility, comfort, and...

  • Charleston
  • 2 Bedrooms
  • 1 Bathrooms
  • Sleeps 4
2 Bedroom/ 2 Bathroom Condo in Heart of ...

Sleep soundly in beds with high thread-count sheets and new memory foam beds. Decorated in modernistic monochrome style, stand-out touches include the suspended designer ceiling lights, offbeat fractured frame mirror, and constructed-in...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 6
Oasis in the Center of Downtown Charlest...

Immerse yourself in Charleston`s vibrant culture from this gorgeous 2-bedroom vacation rental in the historic Cannonborough-Elliotborough neighborhood. This impeccably designed unit features a sophisticated blend of modern and antique furnishings...

  • Charleston
  • 2 Bedrooms
  • 1 Bathrooms
  • Sleeps 4
*Newly Renovated!* Guesthouse Charleston...

Welcome to your home away from home in the heart of Charleston. This handsomely modernized four-bedroom, four-and-a-half-bathroom residence is located on the first floor of a gorgeous two-unit duplex on the highly beautiful Spring Street just steps...

  • Charleston
  • 4 Bedrooms
  • 4 Bathrooms
  • Sleeps 10
Precious Gem - Suite B | Blocks from Kin...

Permit Number: 05686The Space: This professionally designed 2-bedroom, 2-bath getaway offers comfort, style, and a prime downtown Charleston location just two blocks from King Street!With inviting living spaces and thoughtful amenities, it’s an...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 5
Historic Duplex 6 Blocks To King - Lots ...

Summary:Take it painless on the porch after a long day at the beach, then pull up a chair for a casual dinner. This beautiful duplex offers a touch of sophistication tucked into historic downtown Charleston.Think of everything you'd want for your...

  • Charleston
  • 6 Bedrooms
  • 4 Bathrooms
  • Sleeps 12