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Isle of Palms, SC 5+ Bedroom Vacation Rentals

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122 rentals found
521 Carolina Blvd ~ new construction com...

521 Carolina Blvd - Lil’ Pink HouseIsle of Palms, SCOverview: Welcome to “Lil’ Pink House,” a brand-new 6-bedroom, 6.5-bathroom bespoke home finished in March 2024. This striking property offers an unparalleled blend of sophistication and...

  • Isle of Palms
  • 6 Bedrooms
  • 6 Bathrooms
  • Sleeps 12
311 Carolina by AvantStay | Rooftop Ocea...
5.0
(25)

311 Carolina Boulevard is really a rare find with ocean vistas, private pool, four cavernous decks, and striking amenities to meet your every vacation wish. Step into your vacation dream that features five bedrooms, each with a king bed, four full...

  • Isle of Palms
  • 5 Bedrooms
  • 6 Bathrooms
  • Sleeps 12
Luxury Beach Rental! Private Pool & Hot ...
5.0
(1)

Welcome to 3207 Palm BlvdThis family beach home is the ideal combination of luxury and comfort with ample open spaces for either calming poolside or appreciating the ocean vistas from the rooftop deck. The architectural details and windows galore...

  • Isle of Palms
  • 6 Bedrooms
  • 6 Bathrooms
  • Sleeps 16
Discounts! OCEANFRONT STUNNER- Discounte...
4.8
(4)

**Ask about our current discounts for Summer 2025!Tired of looking through tons of listings? Do you need a specific type of home or dates? We are a local family owned company, Exclusive Properties, located right here on Isle of Palms. We specialize...

  • Isle of Palms
  • 7 Bedrooms
  • 6 Bathrooms
  • Sleeps 12
Beachwood West 6 by Wild Dunes, with Acc...

Beachwood West 6 by Wild Dunes5 Bedroom Resort View Home5 Bedrooms | 3.5 Bathrooms | Sleeps 10DescriptionLocated in the exclusive Beachwood neighborhood of Wild Dunes, Beachwood West 6 is a roomy five-bedroom getaway offering privacy, comfort, and...

  • Isle of Palms
  • 5 Bedrooms
  • 2 Bathrooms
  • Sleeps 12
NEW CUSTOM HOME~ 620 Ocean Blvd. Now boo...

Tired of looking through tons of listings? Do you need a specific type of home or dates? We are a local family owned company, Exclusive Properties, located right here on Isle of Palms. We specialize in handsome, luxury or budget friendly vacation...

  • Isle of Palms
  • 7 Bedrooms
  • 9 Bathrooms
  • Sleeps 12
Steps to the Beach! Pool, Gym, Game Room...

Discover the ultimate beach vacation at 3301 Palm! Featuring six bedrooms and sleeping 14 guests, this roomy getaway is the ideal choice on the Island for your next group hideaway. This 3-story home features a private pool, gym, movie theater...

  • Isle of Palms
  • 6 Bedrooms
  • 5 Bathrooms
  • Sleeps 12
Discounts! Beautifully decorated~ 206 Oc...
5.0
(5)

Ask about our Summer 2025 discounts! **This home books Friday to Friday in the Summer months**--Description--Part of our luxury collection, 'Villa Las Palmas', 206 Ocean Blvd., is a seven bedroom, seven and a half bathroom oceanfront home that was...

  • Isle of Palms
  • 7 Bedrooms
  • 7 Bathrooms
  • Sleeps 12
Beautifully Remodeled Modern, Yet Charmi...
5.0
(12)

Your Isle of Palms Heaven Awaits!✨Property Highlights- Private Pool & Putting Green- Ocean Vistas from Second Level- Modern Beachy Decor- Steps to Public Beach Access- $250 Beach Gear Credit with 3-14 nighttime stays!Seriously, get ready to fall...

  • Isle of Palms
  • 5 Bedrooms
  • 4 Bathrooms
  • Sleeps 12
NEWLY BUILT HOME, Min to Beach, Restaura...

Welcome to The Eleanor, a chic, classy hideaway with a great Isle of Palms location. Just a 5-min. walk (.75 miles) from pristine beaches, this 6 bedroom and 4.5 bathroom abode comes with a private heated pool and is steps away from The Refuge...

  • Isle of Palms
  • 6 Bedrooms
  • 4 Bathrooms
  • Sleeps 12
One Block to Beach! Modern 6 Bed with Pr...
3.9
(14)

You found it! The ideal Isle of Palms home. This pretty 6 bedroom/6 bathroom home is located in an ideal location on the island: one block from the ocean with a direct beach access path, a short distance to the IOP Marina, and walking distance to...

  • Isle of Palms
  • 6 Bedrooms
  • 6 Bathrooms
  • Sleeps 12
'Movie Night under the Stars' Free with ...

Welcome to The Graybrooke House! This pristine Isle of Palms beauty is a showstopper with her private pool, 2-block walk to the beach and impressive vistas from every room. Windows flanking the rear of the great room frame ocean vistas and to the...

  • Isle of Palms
  • 6 Bedrooms
  • 7 Bathrooms
  • Sleeps 12
Stay @ Bikinis & Martinis
5.0
(3)

Bikinis and MartinisLocation: Isle of Palms, SCOverview:Welcome to Bikinis and Martinis, a striking 5-bedroom, 5.5-bathroom new construction home located just a block from the beach on Isle of Palms. This luxury getaway offers an open-concept design...

  • Isle of Palms
  • 5 Bedrooms
  • 5 Bathrooms
  • Sleeps 12
302 Charleston by AvantStay | Stunning P...

Welcome to your idyllic hideaway at 302 Charleston Blvd on the enchanting Isle of Palms, SC! This elegant vacation rental home offers five bedrooms and three and a half baths, ensuring ample space for relaxation and recreation. A highlight of this...

  • Isle of Palms
  • 5 Bedrooms
  • 3 Bathrooms
  • Sleeps 10