Charleston-SC.com logo

Charleston, SC 6+ Bedroom Vacation Rentals

Filter 6+ Bedroom Charleston Properties by: Company | Pet-Friendly | or choose different a Area or Bedrooms
No company options available.
Bedrooms:
104 rentals found
Harleston House | Sleeps 16 | Whole Hous...

Summary:Welcome to Harleston House in The Preserve. This premier property is one of our five sophisticated luxury homes located in the heart of downtown Charleston. With 7 handsomely designed bedrooms, each accompanied by a private bath, this...

  • Charleston
  • 7 Bedrooms
  • 7 Bathrooms
  • Sleeps 16
Charming Downtown 6BR - Steps to King St...

Summary:Stay in this cavernous 6BR/6BA Charleston getaway, just steps from King Street. Each bedroom offers a king bed and ensuite bath, giving guests both privacy and comfort. With two full kitchens, multiple living areas, and off-street parking...

  • Charleston
  • 6 Bedrooms
  • 6 Bathrooms
  • Sleeps 14
Morris Place | Best of Charleston Renova...

Summary:Welcome to Morris Place, a attractively remodeled Charleston home celebrated with the Finest of Charleston award for its blend of architectural character and modern comfort. Ideal for guests who adore design, heritage, and intimate outdoor...

  • Charleston
  • 6 Bedrooms
  • 6 Bathrooms
  • Sleeps 16
Historic Duplex 6 Blocks To King - Lots ...

Summary:Take it painless on the porch after a long day at the beach, then pull up a chair for a casual dinner. This pretty duplex offers a touch of sophistication tucked into historic downtown Charleston.Think of everything you'd want for your ideal...

  • Charleston
  • 6 Bedrooms
  • 4 Bathrooms
  • Sleeps 14
Pool! | 2 Blocks to King St | Parthenon ...

Permit Number: 05086The Space: Two homes. Ten bedrooms. Walk to King Street.This broad Charleston getaway is designed for huge groups who want space to gather without sacrificing privacy. Tucked on a peaceful street just a 6-min. walk to King...

  • Charleston
  • 10 Bedrooms
  • 6 Bathrooms
  • Sleeps 20
The Inns | Grand 9BR Charleston Downtown...

Summary:Welcome to your Charleston gathering place where space meets luxury. This huge 9 bedroom home is constructed for sizable groups, offering eight full bathrooms to make everybody’s stay comfortable and convenient. Ideal for family...

  • Charleston
  • 9 Bedrooms
  • 8 Bathrooms
  • Sleeps 16
The Edisto River Complex- 4 Condo Comple...

The PERFECT vacation rental for Weddings, Extensive Groups and Families looking to travel in complete extravagant comfort and privacy! This 4 Condo- 8 Bedroom/ 8 Bathroom Complex is the ONLY property in Charleston that can host your entire event in...

  • Charleston
  • 8 Bedrooms
  • 8 Bathrooms
  • Sleeps 24
Chic Historic Victorian Duplex 2 Blocks ...

Summary:Stay at The Dunes on Spring, our attractively remodeled 1905 Charleston Victorian duplex home in the heart of Cannonborough. Just 2 blocks from King Street, this handsome property features nearly 2600 square feet of ideally designed space...

  • Charleston
  • 6 Bedrooms
  • 3 Bathrooms
  • Sleeps 13
The Queens Palace | 8 Bedrooms in Charle...

Permit Number: 05553The Space: Welcome to The Queen’s Palace, your private Charleston getaway made up of three attractively restored historic homes in the heart of the Cannonborough–Elliotborough neighborhood. With eight bedrooms, eight...

  • Charleston
  • 8 Bedrooms
  • 8 Bathrooms
  • Sleeps 16
Downtown Historic Home Close to Neighbor...

Summary:Welcome to this vibrant downtown getaway! Originally constructed in 1905 and freshly modernized, this colorful home blends historic appeal with modern comfort. With eight uniquely styled bedrooms and eight gorgeously refreshed bathrooms...

  • Charleston
  • 8 Bedrooms
  • 4 Bathrooms
  • Sleeps 16
Thomas Waring House | Sleeps 23 | Multi-...

Summary:Welcome to the Thomas Waring House at The Preserve, a historic and award-winning residence that offers a unique blend of appeal and modern convenience. Comprising 4 separate units, this broad property features a total of 11 bedrooms and 11.5...

  • Charleston
  • 11 Bedrooms
  • 11 Bathrooms
  • Sleeps 23
The OakTree | Stylish Bohemian Downtown ...

Summary:Welcome to The OakTree, your boho-chic haven in the heart of downtown Charleston, where artistic flair meets generous space. Ideal for enormous groups, families, or creative retreats, this 7-bedroom home offers character, comfort, and close...

  • Charleston
  • 7 Bedrooms
  • 7 Bathrooms
  • Sleeps 16
Guesthouse Charleston: SOUTH (82 A & B)

82 A & B is a roomy two-story home, attractively located within walking distance of Charleston's best eateries, bars, and attractions. Ideal for huge groups, the home features two completely equipped kitchens, two living areas, and multiple outdoor...

  • Charleston
  • 8 Bedrooms
  • 9 Bathrooms
  • Sleeps 18
Full House w Bikes, Grill + Patio + Park...

Summary:This home has everything you need for the ideal group trip to Charleston. Located in the heart of Downtown in a safe, beautiful neighborhood, The Rose features six elegantly refreshed bedrooms, two full kitchens, and two roomy living areas...

  • Charleston
  • 6 Bedrooms
  • 4 Bathrooms
  • Sleeps 16
The Manor | 8BR Home in Downtown Charles...

Summary:Step into this attractively preserved Charleston-style home where old-world appeal meets modern comfort. Ideal for couples, families, or modest groups, it offers a welcoming getaway filled with character in a prime location. Located in a...

  • Charleston
  • 8 Bedrooms
  • 4 Bathrooms
  • Sleeps 16
Hot Tub • Private Courtyard • 1 Bloc...

Summary:Welcome to The Palms of Charleston!☀️ Cavernous Private Courtyard with Hot Tub???? 1 Block to King St! Walk to Charleston’s Finest Dining, Shopping & Nightlife???? Ideal for Enormous Groups – Families, Weddings, & Work Retreats???...

  • Charleston
  • 7 Bedrooms
  • 5 Bathrooms
  • Sleeps 14
The Chapel | Grand 8BR Charmer - Walkabl...

Summary:Welcome to The Chapel, a gorgeously restored 8-bedroom gem in Charleston where character, comfort and convenience come together. Ideal for huge families or groups, this home offers roomy common areas, extravagant design details and a...

  • Charleston
  • 8 Bedrooms
  • 8 Bathrooms
  • Sleeps 16
Grand 10 BR Charleston Home with Speakea...

Summary:Draped in Spanish moss and located within a gorgeous Charleston neighborhood, Heirloom on Cannon is a grandiose 10-bedroom, 7-bath getaway blends timeless Southern character with modern luxury. Freshly remodeled in September 2025, this...

  • Charleston
  • 10 Bedrooms
  • 7 Bathrooms
  • Sleeps 26