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Charleston, SC 6+ Bedroom Vacation Rentals

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104 rentals found
The Manor 93 A&B - 2 Newly Renovated Uni...

Welcome to 93 Spring Street, a attractively restored 1880's Charleston home that combines historic appeal with modern amenities. Located just two and a half blocks from King Street, this cavernous home has been thoughtfully divided into two separate...

  • Charleston
  • 7 Bedrooms
  • 7 Bathrooms
  • Sleeps 14
Downtown Historic Home Close to Neighbor...

Summary:Welcome to this vibrant downtown getaway! Originally constructed in 1905 and newly remodeled, this colorful home blends historic appeal with modern comfort. With eight uniquely styled bedrooms and eight handsomely refreshed bathrooms...

  • Charleston
  • 8 Bedrooms
  • 4 Bathrooms
  • Sleeps 16
Great Downtown Charleston Location!

Feel what it means to live like a local in our 2-story Downtown Charleston home. This home is 6 beds / 5.5 baths and would be ideal for sizable groups/families of up to 12 people. Located 1 block off King Street, you can walk to eateries, bakeries...

  • Charleston
  • 6 Bedrooms
  • 5 Bathrooms
  • Sleeps 12
Casa Zoë | Royal House – Charlestonâ€...

Summary:OP2025-06816OP2025-06817The Royal House is Charleston’s ultimate group escape: a dual-unit Casa Zoë mansion that blends grandeur, design, and independence. With 8 bedrooms, 8 baths, and separate living quarters, it offers shared elegance...

  • Charleston
  • 8 Bedrooms
  • 10 Bathrooms
  • Sleeps 16
Quarters on Spring-Rare CHS Retreat for ...

Welcome to The Quarters on Spring, an exceptionally roomy and handsomely refreshed Charleston hideaway located just mins. from the heart of downtown. It is rare to find a home this huge, this updated, and this appealing in such a prime location...

  • Charleston
  • 6 Bedrooms
  • 4 Bathrooms
  • Sleeps 12
Autumn Getaway: Sleeps 16+BackPatio | Ne...

Sleeps up to 16! This modern, freshly refreshed home consists of 2 huge apartments, rentable separately or together. You have a private backyard to relax/dine with a wide umbrella. Wood floors sit beneath exposed beams, w/ stainless steel...

  • Charleston
  • 6 Bedrooms
  • 4 Bathrooms
  • Sleeps 16
1 Block to King & CHS Best Coffee and Re...

The Space: Welcome to your historic Charleston getaway, a delightfully restored 1820 residence combining timeless character with modern comfort in the heart of the city!This property offers two private units, one upstairs and one downstairs, each...

  • Charleston
  • 6 Bedrooms
  • 5 Bathrooms
  • Sleeps 15
Stunning 6-Bedroom Home with Pool, 5.5 B...

More photos coming soon!Dive in to this newly remodeled 6-bedroom, 5.5 bathroom home with a brand new pool, ideal for hosting up to 12 guests. This three-story haven, adorned with wood floor, original fireplaces, and high ceilings with exposed...

  • Charleston
  • 6 Bedrooms
  • 5 Bathrooms
  • Sleeps 12
11 Bed Compound for Large Groups, Prime ...

Summary:Welcome to The Grandiose Estate, a private getaway in the heart of downtown Charleston, SC. Located within a meticulously restored historic home, this exclusive property features four entirely furnished residences, creating the ideal setting...

  • Charleston
  • 11 Bedrooms
  • 8 Bathrooms
  • Sleeps 24
Bee & Blossom | Large Bed & Breakfast Bu...

Summary:Welcome to Bee & Blossom, a gorgeously restored home in Charleston’s historic Radcliffeborough neighborhood. The home blends classic Charleston character with modern comfort. Gather in the inviting living room, prepare meals in the...

  • Charleston
  • 6 Bedrooms
  • 6 Bathrooms
  • Sleeps 12
The Quad at 493 - 4 Suites - Right on Ki...

Permit Number: 004141The Space: Welcome to 493 Luxury Suites! These elegantly appointed units are found on the second floor of a historic building on King Street (above Sewing Down South, as seen on “Southern Charm”).Step into the building...

  • Charleston
  • 8 Bedrooms
  • 8 Bathrooms
  • Sleeps 24
Full House w Bikes, Grill + Patio + Park...

Summary:This home has everything you need for the ideal group trip to Charleston. Located in the heart of Downtown in a safe, charming neighborhood, The Rose features six charmingly refreshed bedrooms, two full kitchens, and two cavernous living...

  • Charleston
  • 6 Bedrooms
  • 4 Bathrooms
  • Sleeps 16
Moultrie & Palmetto Suites | Walk to Bar...

Summary:Welcome to The Moultrie & Palmetto, a modren 6 bedroom, 4 bathroom property spanning two units in the same downtown Charleston building. Sleeps a huge group together while giving everybody their own space to land. Step outside and King...

  • Charleston
  • 6 Bedrooms
  • 4 Bathrooms
  • Sleeps 14
Chic Historic Victorian Duplex 2 Blocks ...

Summary:Stay at The Dunes on Spring, our handsomely remodeled 1905 Charleston Victorian duplex home in the heart of Cannonborough. Just 2 blocks from King Street, this handsome property features nearly 2600 square feet of ideally designed space. The...

  • Charleston
  • 6 Bedrooms
  • 4 Bathrooms
  • Sleeps 12
The Queens Palace | 8 Bedrooms in Charle...

Permit Number: 05553The Space: Welcome to The Queen’s Palace, your private Charleston getaway made up of three attractively restored historic homes in the heart of the Cannonborough–Elliotborough neighborhood. With eight bedrooms, eight...

  • Charleston
  • 8 Bedrooms
  • 8 Bathrooms
  • Sleeps 16
Downtown Duplex - Spring St

Feel the timeless appeal of Charleston’s historic peninsula, the Holy City. Stay just mins. from MUSC, the College of Charleston, and the vibrant shopping, dining, and nightlife of King Street. From this ideally located downtown home, you’ll be...

  • Charleston
  • 8 Bedrooms
  • 8 Bathrooms
  • Sleeps 26
Magnolia House | Historic Charleston Hom...

Summary:Welcome to Magnolia House, a enormous 6 bedroom, 3 bathroom two-story Charleston style home that blends timeless character with comfortable, modern touches. Ideal for families or groups seeking space, beauty, and convenience in one place...

  • Charleston
  • 6 Bedrooms
  • 3 Bathrooms
  • Sleeps 19
Large, Historic 6BR, Designed to Perfect...

Summary:Welcome to Palmetto Hideaway, a impressive 6-bedroom designer home in the heart of downtown Charleston. Ideal for huge families, friend getaways, or anyone who craves style, space, and character, it immerses you in history while offering...

  • Charleston
  • 6 Bedrooms
  • 6 Bathrooms
  • Sleeps 16