Charleston-SC.com logo

Charleston, SC 6+ Bedroom Vacation Rentals

Filter 6+ Bedroom Charleston Properties by: Company | or choose different a Area or Bedrooms
No company options available.
Bedrooms:
108 rentals found
The Rosemary House | Sleeps 16 | Multi-U...

Summary:Welcome to the Rosemary House at The Preserve, a cavernous and elegantly appointed residence occupying the top floors of a gorgeously preserved historic home. With 8 bedrooms and 8 bathrooms, this broad property offers ample privacy and...

  • Charleston
  • 8 Bedrooms
  • 8 Bathrooms
  • Sleeps 16
Casa Bella - Your Oasis in the Heart of ...

Permit Number: 04771,05004The Space: Introducing Casa Bella: A Charming Charleston Retreat with Ample Space and Serene YardLocated in the heart of Charleston, Casa Bella offers a freshly-remodeled haven boasting 6 bedrooms, 4 bathrooms, and divided...

  • Charleston
  • 6 Bedrooms
  • 4 Bathrooms
  • Sleeps 11
Charleston Style Full Duplex - 2 Blocks ...

Welcome to the Holy City, and the historic southern appeal of the Charleston peninsula. Our Vacation Rental By Owner is located in gorgeous downtown Charleston and just mins. away from MUSC, the College of Charleston, and King Street’s shopping...

  • Charleston
  • 6 Bedrooms
  • 4 Bathrooms
  • Sleeps 16
Magnificent 1852 Mansion, Center Histori...
5.0
(1)

Summary:Savor a refined antebellum experience with amenities both new and crafted from reclaimed pieces of Charleston history. The bathroom is tiled using the original 1851 slate from Vermont with cypress ship-lap wood walls and heart pine...

  • Charleston
  • 9 Bedrooms
  • 6 Bathrooms
  • Sleeps 16
Crosstown @ King | Elegant & Modern 6BR ...

Summary:Welcome to "6 Bedroom - Modern Elegance - Heart of Charleston" Our impressive 6-bedroom, 4-bathroom home is located in the vibrant Crosstown neighborhood, just a block off King Street.This entire home is ideal for families and groups looking...

  • Charleston
  • 6 Bedrooms
  • 4 Bathrooms
  • Sleeps 14
The Gardenia House | Sleeps 20 | Multi-U...

Summary:Welcome to the Gardenia House in the Preserve, a distinguished luxury residence located in the heart of downtown Charleston. This chic property offers two exclusive suites within a roomy layout of 7 bedrooms and 7 full baths, making it ideal...

  • Charleston
  • 7 Bedrooms
  • 7 Bathrooms
  • Sleeps 20
The Madison Compound- Entire Charleston ...
5.0
(13)

Encompass yourself in the history of Charleston by staying in this freshly modernized 1890's single home. The Madison Compound offers guests all the aesthetic features of a Charleston Single House from it enormous Piazzas, private roof top deck and...

  • Charleston
  • 6 Bedrooms
  • 7 Bathrooms
  • Sleeps 16
The Edisto River Complex- 4 Condo Comple...
5.0
(4)

The PERFECT vacation rental for Weddings, Sizable Groups and Families looking to travel in complete extravagant comfort and privacy! This 4 Condo- 8 Bedroom/ 8 Bathroom Complex is the ONLY property in Charleston that can host your entire event in...

  • Charleston
  • 8 Bedrooms
  • 8 Bathrooms
  • Sleeps 24
93.5 A&B - New listing! 6 Bedrooms Close...

The property located at 93.5 unit A & B The Manor is a handsome two-story new construction home providing all the amenities of home combined with fresh furnishings and an spectacular location.Unit A is the first-floor unit with an open concept...

  • Charleston
  • 6 Bedrooms
  • 6 Bathrooms
  • Sleeps 16
Mint Julep | Largest Private Pool Downto...
4.8
(30)

Permit Number: 05932The Space: Step into a world of opulence and relaxation at The Mint Julep House, where every detail has been meticulously curated for an extraordinary stay. This two-story residence, newly refreshed and impeccably furnished...

  • Charleston
  • 6 Bedrooms
  • 5 Bathrooms
  • Sleeps 12
2 Luxury Homes w/ Patios | 1 Block from ...

Summary:Discover luxury pair of completely modernized luxury homes ideal for a sizable group, located next door to each other just moments from King St. Indulge in beautiful interiors awash with natural light from wrap-around windows. These...

  • Charleston
  • 8 Bedrooms
  • 7 Bathrooms
  • Sleeps 20
Guesthouse Charleston: WEST (242 B & C)
4.9
(18)

West 242 B and 242 C are two impressive standalone homes located in the heart of Charleston's vibrant Cannonborough/Elliotborough neighborhood, just two blocks from historic King Street. This prime location offers simple access to Charleston's best...

  • Charleston
  • 8 Bedrooms
  • 6 Bathrooms
  • Sleeps 16
Cocktail Club | 4 Redesigned Suites
4.4
(8)

Permit Number: 05591,05592,05593,04688The Space: Savor gracious Southern living in our cavernous 8 BR home. The home is divided into four gorgeously designed 2 BR units, making this property ideal for huge groups. Each unit has been thoughtfully...

  • Charleston
  • 8 Bedrooms
  • 4 Bathrooms
  • Sleeps 18
Center of Charleston - Two Homes - 6BR/6...
4.0
(2)

Summary:Two Sensational Homes in the Heart of Downtown!- 1 block from King Street + all of the shopping, eateries, and bars you could want! - 6 BR/6 BA total + a front porch and balcony porch! - Parking for multiple cars! YourPad Charleston is a...

  • Charleston
  • 6 Bedrooms
  • 6 Bathrooms
  • Sleeps 16
6 Bedrooms! One Block to King Street!
4.7
(11)

Summary:NEWLY RENOVATED, March 2025! New bathrooms and floor! Steps away from eateries and stores! This home is a stand alone, 2-unit home. → One block from famed King Street! → 6 Beds / 4 Baths→ Totally Stocked kitchens → Two living rooms...

  • Charleston
  • 6 Bedrooms
  • 4 Bathrooms
  • Sleeps 14
The Inns | 10 BR Downtown Home - Amazing...
5.0
(1)

Summary:Welcome to The Inns! We are a brand of luxury vacation homes here in Downtown Charleston. All of The Inns are modren, newly modernized, and professionally decorated.- Charleston 9 Bedroom Home + 1 Bedroom Guest Cottage - 7 Full Bathrooms...

  • Charleston
  • 10 Bedrooms
  • 7 Bathrooms
  • Sleeps 26
Magnolia House | Historic Charleston Hom...
4.6
(11)

Summary:Gather your group at this roomy 6BR two-story Charleston style home that blends historic appeal with modern comfort. Just steps from King Street, appreciate eateries, stores, and nightlife at your doorstep. With two kitchens, dining areas...

  • Charleston
  • 6 Bedrooms
  • 3 Bathrooms
  • Sleeps 19
Casa Zoë | Royal House – Charlestonâ€...

Summary:The Royal House is Charleston’s ultimate group escape: a dual-unit Casa Zoë mansion that blends grandeur, design, and independence. With 8 bedrooms, 8 baths, and separate living quarters, it offers shared elegance with private...

  • Charleston
  • 8 Bedrooms
  • 10 Bathrooms
  • Sleeps 16