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4+ Bedroom Pet-Friendly Vacation Rentals

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174 rentals found
7BR Coastal Retreat • Walk to Beach + ...

Just steps from Isle of Palms’ Front Beach scene, 6 10th Avenue puts big-group coastal living right where guests want to be—near the sand, surf, eateries, ice cream stores, and live music that make this Charleston-area beach town so simple to...

  • Isle of Palms
  • 7 Bedrooms
  • 5 Bathrooms
  • Sleeps 15
302 Charleston by AvantStay | Stunning P...

Welcome to your idyllic hideaway at 302 Charleston Blvd on the enchanting Isle of Palms, SC! This elegant vacation rental home offers five bedrooms and three and a half baths, ensuring ample space for relaxation and recreation. A highlight of this...

  • Isle of Palms
  • 5 Bedrooms
  • 3 Bathrooms
  • Sleeps 10
5BR Spring Street Duplex - Walk to King ...

Feel the timeless appeal of Charleston’s historic peninsula, the Holy City. Stay just mins. from MUSC, the College of Charleston, and the vibrant shopping, dining, and nightlife of King Street. From this ideally located downtown home, you’ll be...

  • Charleston
  • 5 Bedrooms
  • 3 Bathrooms
  • Sleeps 10
Gorgeous Beach Home, Ocean Views, w/Priv...

Welcome to 811 Ocean Boulevard on Isle of Palms! – An Enchanting Coastal RetreatStep into a realm of comfort and appeal as you discover this elegant five-bedroom, five-bathroom home located in the heart of Isle of Palms, a heaven for both...

  • Isle of Palms
  • 5 Bedrooms
  • 5 Bathrooms
  • Sleeps 12
The Isla Suite: A Dream Getaway for Frie...

The Isla Suite: A Dream Getaway for FriendsThe Isla Suite is a vibrant first-floor getaway in pretty Charleston, crafted for an memorable friends’ group hideaway. Positioned just steps from downtown’s premier beverage bars, top-rated eateries...

  • Charleston
  • 4 Bedrooms
  • 2 Bathrooms
  • Sleeps 8
Only 1 Block to King! | The Sweetgrass

Permit Number: 06474The Space: Welcome to The Sweetgrass House, a cavernous two level getaway designed for groups of 8–10 guests looking for comfort, privacy, and an painless downtown Charleston stay. With four bedrooms and four full bathrooms...

  • Charleston
  • 4 Bedrooms
  • 4 Bathrooms
  • Sleeps 8
Historic Boutique Home ‘The Palms’

Summary:A short walk from King St. 'The Palms' is a roomy private historic property. The property offers an open kitchen & living area, opening directly to traditional southern piazza. Plenty of space for guests to relax. Property amenities also...

  • Charleston
  • 4 Bedrooms
  • 4 Bathrooms
  • Sleeps 9
‘Pacific Blue’ – Historic Home 5 m...

Summary:'The Pacific Blue' at The Blue Haven is a 5 min. walk to famed King Street. This refreshed historic home includes a modern kitchen, beautiful living area, and a traditional private piazza to lounge in the shade & watch the city go by.The...

  • Charleston
  • 4 Bedrooms
  • 4 Bathrooms
  • Sleeps 8
Private Pool + Fire Pit + Foosball | Sho...

Welcome to Southern Oasis, your dream hideaway on the beachy Isle of Palms! Just 30 mins. from downtown Charleston, Southern Oasis is ideal for those seeking a calming getaway located just outside of the city’s excitement.Brimming with southern...

  • Isle of Palms
  • 5 Bedrooms
  • 4 Bathrooms
  • Sleeps 12
Casa Zoë | Cottage Row – Side-by-Side...

Summary:OP2025-05857OP2025-05858Cottage Row is a rare Charleston find with two completely separate, next-door Casa Zoë cottages that together create the ideal setup for groups who want to be close but still have their own space. Tucked in the...

  • Charleston
  • 4 Bedrooms
  • 4 Bathrooms
  • Sleeps 10
6BD/6BA Downtown Home - 2 Blocks from Ki...

Summary:Welcome to your Charleston sanctuary, a beloved guest-favorite home that combines generous space, fresh amenities, and an unbeatable downtown location. With six full baths and six beds, this home is ideal for huge families or groups who want...

  • Charleston
  • 6 Bedrooms
  • 6 Bathrooms
  • Sleeps 12
The Manor | 8BR Home in Downtown Charles...

Summary:Step into this gorgeously preserved Charleston-style home where old-world appeal meets modern comfort. Ideal for couples, families, or modest groups, it offers a welcoming getaway filled with character in a prime location. Located in a...

  • Charleston
  • 8 Bedrooms
  • 4 Bathrooms
  • Sleeps 16
'Isle be Back' 5 57th Ave- Great Ocean V...

**Summer bookings are Sat. to Sat. We have a 3 nighttime min in the off-season** Description"Isle be Back" - 5 57th Avenue is one of our newest additions. It is a beautiful, six bedroom, five and a half bathroom inverted floor plan home with...

  • Isle of Palms
  • 6 Bedrooms
  • 5 Bathrooms
  • Sleeps 16
James Island Retreat: Hot Tub, Screened ...

Summary:Delightfully remodeled home located under the live oaks on James Island. With 4 bedrooms, 3 full bathrooms, a screened-in porch with a hot tub and TV, and a completely fenced backyard, this home is made for groups who want convenience, and...

  • Charleston
  • 4 Bedrooms
  • 3 Bathrooms
  • Sleeps 9
Spacious 4BR Retreat w/ Huge Yard, Outdo...

Cavernous 4BR home (2x King, 2x Queen) just 12 mins. from Folly Beach and 8 mins. to downtown Charleston. Savor a humongous fenced yard, outdoor shower, fire pit, and a enormous dining table with umbrella and fan—ideal for warm evenings. Located...

  • Charleston
  • 4 Bedrooms
  • 2 Bathrooms
  • Sleeps 8
Downtown Duplex - St Philip St

Feel the timeless appeal of Charleston’s historic peninsula, the Holy City. Stay just mins. from MUSC, the College of Charleston, and the vibrant shopping, dining, and nightlife of King Street. From this ideally located downtown home, you’ll be...

  • Charleston
  • 6 Bedrooms
  • 5 Bathrooms
  • Sleeps 16
16 29th Avenue | Isle of Palms Group Ret...

16 29th Avenue blends coastal appeal and modern comfort for the ideal Isle of Palms getaway. Set about 3 blocks from the beach—just a leisurely 4-min. walk—this home places you within simple reach of sun-soaked shores and the lively Isle of...

  • Isle of Palms
  • 5 Bedrooms
  • 4 Bathrooms
  • Sleeps 10
St. Michael's Place Retreat

St Michael's Place is a short term stay for patients and their families who need to come to Charleston to seek medical treatment. Located in the heart of old James Island, within walking distance to shopping, eateries, nightlife, yoga, farmers...

  • Charleston
  • 4 Bedrooms
  • 1 Bathrooms
  • Sleeps 3