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Charleston, SC 4+ Bedroom Vacation Rentals

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356 rentals found
Entire New 3 Story House w/ Private Heat...

Entire New 3 Story House w/ Private Heated Spa/Pool, Roof Top Deck & Elevator. Brand new home in historic Charleston with private jetted heatable spa/pool and rooftop deck. Located just one block from Upper King Street within the...

  • Charleston
  • 4 Bedrooms
  • 5 Bathrooms
  • Sleeps 12
Palm House | Furnished 5BR MTR in Charle...

Summary:Furnished whole-home rental in West Ashley for stays of 30 nights or more, available February 1 2027. All five bedrooms and three bathrooms are open to guests, including the primary suite with its en suite bathroom. Fenced yard, two...

  • Charleston
  • 5 Bedrooms
  • 3 Bathrooms
  • Sleeps 8
The Salty Tern ~ 4BR Marshfront Retreat ...

Escape to your own slice of the Lowcountry on James Island! This impressive 4BR/2BA marsh front getaway offers handsome vistas, a roomy deck, screened porch, fire pit, and a freshly finished dock—ideal for soaking up Charleston’s coastal appeal...

  • Charleston
  • 4 Bedrooms
  • 2 Bathrooms
  • Sleeps 10
The Chapel | Premier 13BR Estate in Down...

Summary:Welcome to The Chapel, a majestic 13-bedroom estate in downtown Charleston where beauty, space and heritage combine to create an memorable stay. Ideal for enormous families, weddings, get-togethers or special gatherings, this property offers...

  • Charleston
  • 13 Bedrooms
  • 12 Bathrooms
  • Sleeps 16
The Cannon Exchange Building By Charlest...

Feel the pinnacle of Charleston living at the Cannon Exchange Building, a thoughtfully designed luxury property offering two broad residences: The Chateau and The Soirée. Each unit accommodates up to 14 guests, making the building ideal for sizable...

  • Charleston
  • 10 Bedrooms
  • 10 Bathrooms
  • Sleeps 28
Great Downtown Charleston Location!

Feel what it means to live like a local in our 2-story Downtown Charleston home. This home is 6 beds / 5.5 baths and would be ideal for enormous groups/families of up to 12 people. Located 1 block off King Street, you can walk to eateries, bakeries...

  • Charleston
  • 6 Bedrooms
  • 5 Bathrooms
  • Sleeps 12
5BR Group House | Fire Pit, Movie Deck &...

☆☆ HIGHLIGHTS ☆☆✔ 5 bedrooms, 7 beds, and 3 bathrooms with room for up to 13 guests✔ The entire property is yours, with no one else on site✔ Arcade machine loaded with classics like Pac-Man and Dig Dug✔ Projector deck with a gas fire...

  • Charleston
  • 5 Bedrooms
  • 3 Bathrooms
  • Sleeps 13
Lovely 4BR/2BA Home! Less Than 10 Minute...

Our pretty 4 bedroom/2 bath home is ideally located in the heart of the charming James Island neighborhood. Drive 10 mins. to Downtown Charleston and 8 mins. to Folly Beach. The 1510 square foot single-level home has four bedrooms and two full...

  • Charleston
  • 4 Bedrooms
  • 2 Bathrooms
  • Sleeps 7
Private Pool | Only 1 Block to King | Su...

Permit Number: 06857The Space: Welcome to your Charleston hideaway, a attractively modernized getaway designed for calming, reconnecting, and making lasting memories together. With bright modern interiors and plenty of space to spread out, this four...

  • Charleston
  • 4 Bedrooms
  • 2 Bathrooms
  • Sleeps 9
Spacious, Large 4bd w/ Outdoor Dining, n...

Summary:Feel the ideal fusion of history and modern luxury at this exceptional 4-bedroom, 3-bath residence. This handsomely modernized home offers an elevated getaway in the heart of the city. Located just three blocks from vibrant King Street...

  • Charleston
  • 4 Bedrooms
  • 3 Bathrooms
  • Sleeps 9
Private Pool! | Rooftop Patio | The Athe...

Permit Number: 07351The Space: Welcome to Athena, a charmingly appointed three-story downtown hideaway designed for bringing people together. Featuring five bedrooms, three-and-a-half bathrooms, a striking private pool, and a light-filled...

  • Charleston
  • 5 Bedrooms
  • 3 Bathrooms
  • Sleeps 10
B2 at Saint Philip Square, One Block to ...

Welcome to appealing Saint Philip Square, a esteemed collection of 6 historic homes spanning nearly a city block of downtown Charleston. The Adams Bennett House at 174 Unit B#2 Saint Philip St. is a classic upstairs 4BD/5BA unit blending modern...

  • Charleston
  • 4 Bedrooms
  • 5 Bathrooms
  • Sleeps 14
Professionally Designed 5bd Retreat, Ste...

Summary:Welcome to Emerson Square, a enormous professionally designed getaway of a delightfully restored historic building, this broad five-bedroom residence is ideal for families and sizable groups. Appreciate a chef’s kitchen, SMART TVs...

  • Charleston
  • 5 Bedrooms
  • 4 Bathrooms
  • Sleeps 15
Charleston Extended Stay w/ Yard!

2,100 Sq Ft | 10 Mi to DowntownThis beautiful Charleston vacation rental offers the ideal destination for a family getaway! Located 17 miles from Folly Beach, this home lets you appreciate the sun and sand before heading back to relax in front of...

  • Charleston
  • 4 Bedrooms
  • 2 Bathrooms
  • Sleeps 6
Downtown 9BR Mansion with Gym Access + P...

Summary:Recently modernized with two full kitchens and modren decor, this home comfortably accommodates your entire event. Located in the heart of the city, the Heirloom on Spring extravagant getaway blends historic character with modern comfort...

  • Charleston
  • 9 Bedrooms
  • 6 Bathrooms
  • Sleeps 16
The Chapel | Estate 5BR Gem in Downtown ...

Summary:Welcome to your Charleston sanctuary, a attractively preserved 5-bedroom gem appealingly located in the heart of downtown. Boasting historic architecture, broad common rooms, and thoughtful modern amenities, this home is ideal for families...

  • Charleston
  • 5 Bedrooms
  • 4 Bathrooms
  • Sleeps 12
Casa Zoë: Bright Charleston Cottage Nea...

Summary:OP2026-07256OP2026-07257Point of View Cottage is a bright and airy Casa Zoë getaway made from two seamlessly connected spaces - ideal for families, friends, or groups who want to stay together but still savor a bit of breathing room. With...

  • Charleston
  • 5 Bedrooms
  • 4 Bathrooms
  • Sleeps 14
High Society | Historic District Gem Nea...

Summary:Feel High Society in this charming 6-bedroom, 3-bath home in Charleston’s Historic District. Unwind on private balconies with city vistas and appreciate the rare perk of off-street parking for four. Just blocks from King Street and the...

  • Charleston
  • 6 Bedrooms
  • 4 Bathrooms
  • Sleeps 12