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Charleston, SC 2+ Bedroom Vacation Rentals

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1051 rentals found
Cooper River Cottage

This home is just a 10-min. walk from Downtown Charleston and the Cooper River. This comfortable home offers well-furnished living spaces, a full kitchen, and cozy bedrooms. You’ll be near King Street’s stores, eateries, and galleries, with...

  • Charleston
  • 2 Bedrooms
  • 3 Bathrooms
  • Sleeps 6
Cozy 2BR Pet Friendly Walkable Resort Co...

Summary:Bowen VillageThe Space:Unwind at this distinctive and serene getaway. The 2-bedroom unit is ideal for your Charleston, SC vacation. It's conveniently located just 20 mins. from the beach, downtown, and Shipyard Park, and a mere 10 mins. from...

  • Charleston
  • 2 Bedrooms
  • 1 Bathrooms
  • Sleeps 4
In the Heart of King Street | Folly Suit...

Permit Number: 004141The Space: Welcome to your second-floor getaway in a gorgeously restored historic building at iconic 493 King Street—right above Sewing Down South, featured on Southern Charm. Step outside and you’re instantly immersed in...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 6
Beautiful Cottage-Style Home Minutes Fro...

Welcome to Charlie’s Charming Cottage! This handsome bungalow-style home is tucked away in a peaceful, centrally located neighborhood and has all the appeal, comfort, and amenities to make it your home away from home. Only 10 mins. to downtown...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 4
3BR Sleeps 6 | Dual Porches, Parking & B...

Summary:The Kiawah Suite features a handsome three queen bedrooms and two baths, as well as a full kitchen and living space. Located on the 1st floor of a historic Charleston home constructed in the late 1800s, this suite overlooks Cannon Street's...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 6
The Heart of Charm: Discover Downtown Ch...

Welcome to your newly modernized home, a striking getaway designed for comfort and relaxation. This pretty space comfortably accommodates four guests, making it ideal for families or friends traveling together. For additional guests, a comfortable...

  • Charleston
  • 2 Bedrooms
  • 1 Bathrooms
  • Sleeps 6
Strawberry Lane: Modern 3BR in Downtown ...

This downstairs apartment in a historic duplex has been freshly remodeled with all new furnishings and amenities. It offers a roomy full kitchen, with a table to seat 6, and a full array of cookware. The living room comes with new flat screen TV...

  • Charleston
  • 3 Bedrooms
  • 1 Bathrooms
  • Sleeps 6
NEW Home | Close to DT & Beaches | 4 BR,...

Summary:Welcome to Coastal Comfort!Unwind in this bright and modern new construction home. It features a cavernous kitchen, four comfortable bedrooms, and a beach-inspired design. Savor complimentary beach gear and make this your ideal home base for...

  • Charleston
  • 4 Bedrooms
  • 2 Bathrooms
  • Sleeps 10
New Charleston meets Old Charleston!

https://youtu.be/yoy7_cTP81w Video Link to U-tube PageFirst time on the Vacation Rental By Owner market! This appealing monthly rental home is located in the French Quarter in a rather residential area called the Exchange, for its proximity to...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 6
The Beat | 2BR in the Heart of Downtown ...

Summary:Welcome to your Charleston hideaway a gorgeous 2-bedroom getaway rich in historic character and thoughtful modern touches. Ideal for solo travelers or couples who appreciate warmth style and architectural detail in a walkable location.The...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 5
Steps from King St | Historic Charm | Th...

Permit Number: 07078The Space: Welcome to The Sutton Suites, two attractively designed homes within the same historic building (constructed in 1852), offering the ideal setup for groups who want to stay close while still appreciating privacy...

  • Charleston
  • 3 Bedrooms
  • 3 Bathrooms
  • Sleeps 8
Just Blocks from King St | Sweetgrass (S...

Permit Number: 06474The Space: Welcome to Sweetgrass (Unit A), a light and airy first floor condo designed for comfort and simple living just steps from Spring Street. Ideal for up to four guests, this inviting home offers a casual Charleston...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 4
Morris Place | Best of Charleston Renova...

Summary:Welcome to Morris Place, a elegantly remodeled Charleston home celebrated with the Finest of Charleston award for its blend of architectural character and modern comfort. Ideal for guests who appreciate design, heritage, and intimate outdoor...

  • Charleston
  • 6 Bedrooms
  • 6 Bathrooms
  • Sleeps 16
Casa Zoë | Royal Cottage I – Designer...

Summary:OP2025-06816Royal Cottage I is a design-rich Casa Zoë getaway, combining classic Charleston appeal with gallery-style interiors and thoughtful details throughout. Featuring four bedrooms and five baths, vaulted ceilings, Slim...

  • Charleston
  • 4 Bedrooms
  • 5 Bathrooms
  • Sleeps 8
West Ashley vacation home 11 minutes fro...

In the enchanting West Ashley area, merely a brief 11-min. car ride from the Port of Charleston's Cruise Terminal, this holiday home provides an ideal getaway for your stay in Charleston. As you step inside, you'll be greeted by a entirely outfitted...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 6
The Mary Scott Suite In the Heart of Cha...

Permit Number: 06948The Space: Welcome to the Mary Scott Suite—where Charleston history meets appeal and comfort!Constructed in 1813, this elegantly preserved home invites you to experience the elegance and character of historic Charleston while...

  • Charleston
  • 3 Bedrooms
  • 1 Bathrooms
  • Sleeps 4
Retreat Near the Charleston Greenway-Wat...

Cavernous and family-friendly getaway ideally located near the Charleston Greenway with calming tidal water vistas. This 4-bedroom, 2.5-bath home offers plenty of room for groups of all sizes, featuring three bedrooms with comfortable queen beds and...

  • Charleston
  • 4 Bedrooms
  • 3 Bathrooms
  • Sleeps 9
The OakTree | Newly Renovated 2BR Downto...

Summary:Welcome to your fresh downtown Charleston sanctuary, a elegantly refreshed home that offers generously sized rooms, modern amenities, and calming outdoor spaces. Ideal for travelers who want room to stretch out, savor comfort and style, and...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 5