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Charleston, SC 2+ Bedroom Vacation Rentals

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1051 rentals found
Cozy Furnished James Island home 3- Mile...

Totally Furnished and located just off of Folly Rd., this premier location between Folly Beach and Downtown Charleston is an ideal spot. Looking for that ideal place escape the hustle of the big city life? Work from home for the year and take...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 6
4 Bedrooms - 4 Blocks to King Street wit...

Feel the timeless appeal of Charleston’s historic peninsula, the Holy City. Stay just mins. from MUSC, the College of Charleston, and the vibrant shopping, dining, and nightlife of King Street. From this ideally located downtown home, you’ll be...

  • Charleston
  • 4 Bedrooms
  • 2 Bathrooms
  • Sleeps 10
Coastal Comfort in Charleston - Family +...

Welcome to Coastal Comfort, your Charleston home away from home! This 3-bedroom, 2-bath getaway offers the ideal blend of relaxation and convenience — located in a peaceful, family-friendly neighborhood just mins. from Avondale, the airport, and...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 6
4 Blocks from King! | Maison de Jasmine ...

Permit Number: 06970The Space: Located in one of Downtown Charleston’s most sought-after neighborhoods, this chic 3-bedroom, 4-bath second-floor home offers comfort, space, and refined design with a roomy private balcony!Thoughtfully curated art...

  • Charleston
  • 3 Bedrooms
  • 4 Bathrooms
  • Sleeps 6
Spring St - Downtown - Walk Everywhere!

Feel the timeless appeal of Charleston’s historic peninsula, the Holy City. Stay just mins. from MUSC, the College of Charleston, and the vibrant shopping, dining, and nightlife of King Street. From this ideally located downtown home, you’ll be...

  • Charleston
  • 4 Bedrooms
  • 4 Bathrooms
  • Sleeps 14
Full House w Bikes, Grill + Patio + Park...

Summary:This home has everything you need for the ideal group trip to Charleston. Located in the heart of Downtown in a safe, charming neighborhood, The Rose features six delightfully refreshed bedrooms, two full kitchens, and two cavernous living...

  • Charleston
  • 6 Bedrooms
  • 4 Bathrooms
  • Sleeps 16
Luxury Equestrian Estate Resort near Cha...

The "Island Bird House" is located on a private Equestrian estate. This newly constructed showcase is a rustically unique 2 Bedroom, 2 Bath, with a recreational space on the ground level. A chef's kitchen with Samsung stainless steel appliances...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 4
The Preserve | Rosemary House Unit C | 5...

Summary:Welcome to the Rosemary House-Suite C at The Preserve, a roomy and elegantly appointed residence occupying the upper floors of a delightfully preserved historic home. With 5 bedrooms and 5 bathrooms, this property offers ample privacy and...

  • Charleston
  • 5 Bedrooms
  • 5 Bathrooms
  • Sleeps 10
Renovated 2BR Downtown Gem Near King

Summary:Savor this freshly refreshed 2BR/2BA condo in Charleston’s Cannonborough neighborhood. Just one block from King Street, this central getaway blends historic appeal with modern finishes.The Space:Ideal for up to 5 guests, this classy stay...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 6
Casa Bella Suite B | 3 Blocks to King St...

Permit Number: OP2026-07333The Space: Welcome to Casa Bella B, a bright and beautiful second floor getaway in the heart of downtown Charleston where historic appeal and modern comfort come together just steps from some of the city’s favorite local...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 5
6B at Saint Philip Square, One Block to ...

Come experience a luxury stay in the heart of Charleston at Saint Philip Square. Our award-winning collection of historic homes spans nearly one city block, The Aiken House, a 3-bed 3-bath gem that blends modern comfort with Charleston`s rich...

  • Charleston
  • 3 Bedrooms
  • 3 Bathrooms
  • Sleeps 6
3bd House w. Parking, 1 block to King!

Summary:Feel Charleston in this attractively modernized 3-bedroom home located in the heart of Downtown. Featuring an open-concept living space, entirely equipped gourmet kitchen, Intelligent TVs, high-speed Wi-Fi, complimentary parking, and...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 6
Private Porch Blocks to King | Casa Fueg...

Permit Number: 07352The Space: Welcome to Casa Fuego, a attractively modernized getaway occupying the second and third floors of a classic Charleston Single home, offering space, appeal, and a lively downtown location just off Spring Street!Bedrooms...

  • Charleston
  • 4 Bedrooms
  • 4 Bathrooms
  • Sleeps 8
The Manor 93A by Guesthouse Charleston

The Manor 93 A is a handsomely designed 1880's Charleston home offering 4 en-suite bedrooms, an open main floor, and a patio ideal for alfresco dining. Only 2.5 blocks to King St, with stores, eateries, and landmarks like the Battery and Market all...

  • Charleston
  • 4 Bedrooms
  • 4 Bathrooms
  • Sleeps 8
St. Michael's Place Retreat

St Michael's Place is a short term stay for patients and their families who need to come to Charleston to seek medical treatment. Located in the heart of old James Island, within walking distance to shopping, eateries, nightlife, yoga, farmers...

  • Charleston
  • 4 Bedrooms
  • 1 Bathrooms
  • Sleeps 3
Renovated 4BR Downtown w. Gym Access + P...

Summary:Freshly painted and upgraded with brand-new beds and linens, the home is filled with natural light and timeless Southern character. Appreciate coffee or a home-cooked meal in the completely equipped kitchen before heading out to discover...

  • Charleston
  • 4 Bedrooms
  • 3 Bathrooms
  • Sleeps 12
Walk to King St | Sleeps 10 | Rooftop | ...

Summary:Escape to The Spring, a 4-bedroom luxury villa in the heart of Charleston! Just steps from King Street, this getaway offers extravagant comfort with three king suites, a private rooftop deck, and walkable access to the city's best...

  • Charleston
  • 4 Bedrooms
  • 3 Bathrooms
  • Sleeps 10
The Rutledge Avenue Inn Historic Charles...

Permit Number: 05608The Space: Rutledge Avenue Inn, Units A, B and C, is a handsomely restored 5-bedroom, 5-bath Charleston gem with two additional half baths, offering the ideal blend of privacy, appeal, and modern comfort. Guests appreciate...

  • Charleston
  • 5 Bedrooms
  • 5 Bathrooms
  • Sleeps 10