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Charleston, SC 2+ Bedroom Vacation Rentals

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1077 rentals found
The Laurel Oak House

Unwind with the whole group at this peaceful place to stay. Welcome to Laurel Oak House—your fun, shaded hideaway under a canopy of Carolina trees! This 3-bedroom getaway sleeps 8 and is packed with ways to relax. Gather for games, grille out on...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 10
The Trifecta at 493 - 3 Suites - On King...

Permit Number: 004141The Space: Welcome to 493 Luxury Suites! These handsomely appointed units are found on the second floor of a historic building on King Street (above Sewing Down South, as seen on “Southern Charm”).Step into the building...

  • Charleston
  • 6 Bedrooms
  • 6 Bathrooms
  • Sleeps 18
Bee St - Downtown w/ Parking - Walk Ever...

Feel the timeless appeal of Charleston’s historic peninsula, the Holy City. Stay just mins. from MUSC, the College of Charleston, and the vibrant shopping, dining, and nightlife of King Street. From this ideally located downtown home, you’ll be...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 5
3 Mi to Beach, Waterfront Charleston Hom...

Kayaks Included | Outdoor Movie Nights | 7 Mi to Historic DowntownUnwind in style and prepare for ample coastal adventures when you stay at this freshly refreshed vacation rental in the Lighthouse Point community. After taking your boat out for a...

  • Charleston
  • 4 Bedrooms
  • 2 Bathrooms
  • Sleeps 9
Close To Folly Beach & Charleston, Charm...

This brand new, super clean, peaceful and conveniently located home is an ideal place for a enormous family or two couples to share. It has two bedrooms with nice comfortable queen beds, two full baths, plus a queen sized pull out couch bed in the...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 6
5 minutes to downtown, short drive to be...

Quiet neighborhood behind the golf course. Walking distance to shop, historic site, grocery, food and more. You are just over the bridge to downtown Charleston. The beach is a short drive for a good experience of Charleston.

  • Charleston
  • 2 Bedrooms
  • 1 Bathrooms
  • Sleeps 4
St. Philip Collection - Pair of newly re...

This listing is combined of two traditional style Charleston row homes with great outdoor space. The two homes are directly beside each other and have their own separate entrances. Each home has plenty of space to all gather together may it be...

  • Charleston
  • 5 Bedrooms
  • 6 Bathrooms
  • Sleeps 14
Historic Downtown Home - Luxury Stay On ...

Feel the timeless appeal of Charleston’s historic peninsula, the Holy City. Stay just mins. from MUSC, the College of Charleston, and the vibrant shopping, dining, and nightlife of King Street. From this ideally located downtown home, you’ll be...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 10
Heart of Historic District | Luxury Apt ...

Located along historic King Street, this 1,050-square-foot apartment offers a sense of space and calm with all the amenities of home.Each of the two king bedrooms is tailored for rest, featuring ceiling fans and sound machines for an simple...

  • Charleston
  • 2 Bedrooms
  • 1 Bathrooms
  • Sleeps 4
Casa Zoë | Elegant 3BR Retreat Near Kin...

Summary:OP2025-05861Palmetto Cottage is a signature Casa Zoë stay—effortlessly classy, light-filled, and ideally placed. With three ensuite bedrooms, open living spaces, and a attractively appointed kitchen, it’s designed for painless...

  • Charleston
  • 3 Bedrooms
  • 3 Bathrooms
  • Sleeps 8
Manor House Suite in Historic Cannonboro...

Summary:The Kiawah Suite features a handsome three bedrooms and two baths, as well as a full kitchen and living space. Located on the 1st floor of a historic Charleston home constructed in the late 1800s, this suite overlooks Cannon Street's...

  • Charleston
  • 3 Bedrooms
  • 3 Bathrooms
  • Sleeps 6
Stylish 5BR/5BA Downtown Retreat - Walk ...

Summary:Stay in this newly remodeled 5-bedroom, 5-bathroom downtown getaway accommodating up to 12 guests. Featuring open concept living areas, a entirely equipped kitchen, opulent king beds, and off-street parking. Just one block from King Street...

  • Charleston
  • 5 Bedrooms
  • 5 Bathrooms
  • Sleeps 12
8 Bedroom - Close to King Street - with ...

Feel the timeless appeal of Charleston’s historic peninsula, the Holy City. Stay just mins. from MUSC, the College of Charleston, and the vibrant shopping, dining, and nightlife of King Street. From this ideally located downtown home, you’ll be...

  • Charleston
  • 8 Bedrooms
  • 4 Bathrooms
  • Sleeps 16
Boutique Home & Resort Pool ‘The Kiawa...

Summary:A short walk from King St. 'The Kiawah' is a roomy private historic property. Rare downtown amenities include the phenomenal shared Spring Island Collection Pool. The property offers an open kitchen & living area, opening directly to...

  • Charleston
  • 3 Bedrooms
  • 4 Bathrooms
  • Sleeps 9
Furnished 3BR Near Folly Beach. King Bed...

Available January & February only | 30+ day stays.Totally furnished 3-bedroom, 2-bath home located in a peaceful residential pocket of James Island, just mins. from Folly Beach and Downtown Charleston..This is a private, cavernous portion of a...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 8
Open And Airy Penthouse Apartment 4 Bloc...

Forth floor penthouse apartment with vistas of the Ravennel Bridge and spectacular sunsets from the 300 foot rooftop terrace overlooking Simonton Park. 2 Bedrooms with ensuites and a powder bath for guests. The kitchen is a chef's dream with a 12...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 4
Beautiful Townhome 10 min from Charlesto...

This striking 3 Bedroom, 2.5 Bathroom Townhome is pretty from top-to-bottom! Located in Mount Pleasant, SC, this home is located in a thriving area with tons of great places to see. It is just mins. from downtown, and two local resort island...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 6
Vacation Villa 5 mins to King St- ‘The...

Summary:Vacation Villa 5 min. walk to King St, in the heart of downtown Charleston. This tropical getaway offers sleek design, soaring 25’ ceilings, open first floor kitchen & living room, and roomy bedrooms with en-suite spa bathrooms. The Palm...

  • Charleston
  • 5 Bedrooms
  • 5 Bathrooms
  • Sleeps 14