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Charleston, SC 2+ Bedroom Vacation Rentals

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1052 rentals found
Cozy Furnished James Island home 3- Mile...

Entirely Furnished and located just off of Folly Rd., this premier location between Folly Beach and Downtown Charleston is an ideal spot. Looking for that ideal place escape the hustle of the big city life? Work from home for the year and take...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 6
The Agave- 3 Bedroom Historic Cottage

Welcome to this striking 3-bedroom, 2-bathroom historic bungalow in downtown Charleston! Immerse yourself in the rich history and vibrant culture of Charleston while appreciating the comfort and convenience of this thoughtfully restored home.Step...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 6
Wonderful 3BDR Guest Suite Sits Between ...

Welcome to your relaxing getaway on James Island! Our 3br 1ba unit is located 4 miles from Folly Beach and 8 miles from downtown. You'll be able to appreciate all the benefits of both the city and the beach. This elegant home has a private main...

  • Charleston
  • 3 Bedrooms
  • 1 Bathrooms
  • Sleeps 6
Six on Cannon | 6BR Charleston Home + Pa...

Summary:Welcome to Six on Cannon, a roomy 6 bedroom 2 bathroom home ideally suited for families, friends, or get-togethers who want room, style, and downtown convenience together. Freshly furnished and thoughtfully arranged, it gives you all the...

  • Charleston
  • 6 Bedrooms
  • 2 Bathrooms
  • Sleeps 16
Boho Ferry- Mins from Credit One- Pet Fr...

Master- King bed, Ensuite bathroomGuest Room- King bed, Ensuite BathroomPack and Play included*Please Note: We operate our homes like a luxury hotel, just check in with a code and leave your towels on the floor when you check out. We take care of it...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 4
Chic 2 Bedroom Spring St Retreat - Walk ...

Feel the timeless appeal of Charleston’s historic peninsula, the Holy City. Stay just mins. from MUSC, the College of Charleston, and the vibrant shopping, dining, and nightlife of King Street. From this ideally located downtown home, you’ll be...

  • Charleston
  • 2 Bedrooms
  • 1 Bathrooms
  • Sleeps 4
Guesthouse Charleston: SOUTH (105 ALL)

This combined listing for South 105 A, B, & 105.5 is a great space for enormous groups. Each unit has 4 bedrooms, and 4.5 bathrooms totalling 12 bedrooms, 12 full bathrooms, 3 half bathrooms, 3 full kitchen/living areas. Located on the desired...

  • Charleston
  • 12 Bedrooms
  • 13 Bathrooms
  • Sleeps 28
Charming Bungalow w/ Koi Pond Porch & Fi...

This beautiful bungalow offers a relaxing getaway just 5 mins. from historic downtown Charleston and 15 mins. from Folly and Sullivan’s beaches. Savor mornings on the screened porch overlooking a koi pond and evenings by the outdoor fireplace...

  • Charleston
  • 2 Bedrooms
  • 1 Bathrooms
  • Sleeps 4
Downtown, 2 Beds, Rosemary Suite

Summary:Welcome to the Rosemary Suite C at The Preserve, a striking upper-level getaway in a elegantly restored historic home. This 2-bedroom, 2-bath rental offers a private and chic stay while maintaining the home’s rich character. While the full...

  • Charleston
  • 2 Bedrooms
  • 3 Bathrooms
  • Sleeps 4
The Elliotborough Suite | Prime 4BR Near...

Summary:Welcome to your Charleston luxury stay where privacy, elegance and convenience converge. This four-master home is ideal for groups or families who appreciate modren design and want independent space for everybody. You will savor generous en...

  • Charleston
  • 4 Bedrooms
  • 4 Bathrooms
  • Sleeps 12
Perfect Location | Emerald House

Permit Number: 07172The Space: Welcome to The Emerald Suite, a warm and inviting carriage home getaway offering privacy, appeal, and comfort in the heart of downtown Charleston. Ideal for groups of six to eight guests, this charmingly refreshed...

  • Charleston
  • 3 Bedrooms
  • 3 Bathrooms
  • Sleeps 6
Private Pool & Historic Home ‘Summer H...

Summary:A short walk to famed King Street, 'The Summer Haze' is a private Charleston home, with private pool! Renovated with modern amenities, experience the appeal of a traditional Charleston home, with comfortable bedrooms & en suite bathrooms...

  • Charleston
  • 4 Bedrooms
  • 4 Bathrooms
  • Sleeps 9
Stylish 3bd House with Parking + Outdoor...

Summary:Welcome to The Copper, a modren and inviting Charleston getaway located just one block from the energy and excitement of Upper King Street. Ideal for families, friends, wedding guests, and business travelers alike, this thoughtfully designed...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 5
Hidden Gem • Close to Downtown & Beach...

Summary:Welcome to Lowcountry Lookout ???? A calming marsh front getaway in the heart of West Ashley! Surrounded by charming oak trees, you’re just mins. from Charleston’s top attractions, eateries, beaches, and historic sites. Unwind by the...

  • Charleston
  • 4 Bedrooms
  • 2 Bathrooms
  • Sleeps 8
The Mary Scott Suite In the Heart of Cha...

Permit Number: 06948The Space: Welcome to the Mary Scott Suite—where Charleston history meets appeal and comfort!Constructed in 1813, this attractively preserved home invites you to experience the elegance and character of historic Charleston...

  • Charleston
  • 3 Bedrooms
  • 1 Bathrooms
  • Sleeps 4
Beautiful 6BR / 6BA w. Parking, Walk to ...

Summary:Welcome to this refined 6-bedroom, 6-bathroom home from The Heirloom collection. Professionally designed and freshly modernized, it offers modren comfort mins. from King Street’s vibrant energy, ideal for sizable groups seeking luxury and...

  • Charleston
  • 6 Bedrooms
  • 6 Bathrooms
  • Sleeps 16
1 Block to King St | Plunge Pool | Sleep...

Summary:Feel luxury at The Pink Palm, a gorgeous new construction 4-bedroom, 4-bathroom getaway in downtown Charleston finished in APR 2025. Appreciate roomy living areas, chic baths, and a completely equipped kitchen. Unwind in the private plunge...

  • Charleston
  • 4 Bedrooms
  • 4 Bathrooms
  • Sleeps 10
Beautiful 4BR DT Charleston - Best Locat...

Summary:Welcome to The Rutledge House, your vibrant downtown Charleston getaway where style, space, and location align handsomely. Ideal for families or groups of friends, this 4-bedroom home offers thoughtful design elements, and walkable access to...

  • Charleston
  • 4 Bedrooms
  • 3 Bathrooms
  • Sleeps 10