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Charleston, SC 2+ Bedroom Vacation Rentals

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1056 rentals found
EAST 46 E - Ground Floor Unit!

Located just one block off King Street in the vibrant Cannonborough/Elliotborough neighborhood, East 46 - E is a chic 2-bedroom, 2-bath ground-floor apartment. Appreciate painless access to local eateries, stores, coffee stores, and everything...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 6
1905 Victorian Historic Home Just 2 Bloc...

Summary:Stay at our impressive 1905 Charleston Victorian home in the heart of Cannonborough. Just 2 blocks from King Street, this property features 3 full-sized bedrooms with king beds and 3.5 bathrooms.The Space:The 3 full bedrooms all include King...

  • Charleston
  • 3 Bedrooms
  • 3 Bathrooms
  • Sleeps 6
Spacious 3BR in Pet Friendly Walkable Re...

Summary:Bowen VillageThe Space:Welcome to your freshly refreshed classy 3-bedroom, 2-bath guest suite located in the heart of the vibrant, walkable village of Bowen! Savor the ideal blend of luxury and convenience, just steps away from an array of...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 6
Cozy Two-Story Home with Outdoor Fun

This cavernous two-story home is designed with families and groups in mind, offering plenty of room to relax, gather, and appreciate your stay. The home serves as a four-bedroom property with flexible sleeping arrangements, including a king bed in...

  • Charleston
  • 4 Bedrooms
  • 2 Bathrooms
  • Sleeps 10
Historic Secluded Haven | The Pentas Hom...

Permit Number: 07281The Space: Welcome to The Pentas, a calming two-story 2-bedroom, 1.5-bath getaway in historic Charleston, offering privacy, comfort, and a prime walkable location.Savor a serene patio with outdoor dining and a secret garden feel...

  • Charleston
  • 2 Bedrooms
  • 1 Bathrooms
  • Sleeps 4
Cottage by Folly Beach with water views

Stunning sunsets from the gigantic deck of our James Island home. 2 miles from Folly Beach, this 2 bedroom, 2 full bath home has everything you will need for a comfortable, serene vacation. Plenty of off street parking and 15 min from downtown with...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 4
Luxe Retreat | Near DT & Beaches | 4 BR,...

Summary:Welcome to Southern Shore! Unwind in this bright and modern NEW CONSTRUCTION home on James Island ideal for up to 10 guests. Appreciate an open layout, roomy kitchen, 4 comfortable bedrooms, and complimentary beach gear. Unwind in the...

  • Charleston
  • 4 Bedrooms
  • 2 Bathrooms
  • Sleeps 10
Historic Home 2 Blocks To King, Backyard...

Summary:Feel a impressive getaway in this historic 1872 bungalow, just two blocks from King Street, located in the heart of downtown Charleston. Featuring three bedrooms and three en suite bathrooms all on the first floor, this charmingly remodeled...

  • Charleston
  • 3 Bedrooms
  • 3 Bathrooms
  • Sleeps 6
Downtown - Near Historic Cigar Factory w...

Welcome to the Holy City, and the historic southern appeal of the Charleston peninsula. Our vacation rental is located in pretty downtown Charleston and just mins. away from MUSC, the College of Charleston, and King Street’s shopping and...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 8
Stylish Getaway in Downtown Charleston

Summary:Discover a guest-favorite getaway just steps from the best of Charleston. Ideal for couples, families, or modest groups seeking an elevated stay, it’s mins. from top eateries, stores, and landmarks, with simple access to galleries...

  • Charleston
  • 2 Bedrooms
  • 1 Bathrooms
  • Sleeps 5
Spacious 2bd Suite w. King Beds, Parking...

Summary:The Heirloom on Spring is a impressive 2-bedroom, 2-bath getaway embodies the essence of historic Charleston living. Bright and airy with high ceilings and timeless character, it features a entirely outfitted kitchen ideal for home-cooked...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 4
Charleston | Historic City Retreat | Gym...

Feel the quintessential appeal of South Carolina's Lowcountry at Liberty Place Charleston, a Hilton Club, a boutique urban sanctuary located in historic downtown Charleston. Seamlessly blending classic southern elegance with modern refinement, this...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 6
Guesthouse Charleston: EAST (46 H)

East 46 - H is a roomy three-story, 3-bedroom, 3-bathroom apartment located just one block off King Street in Charleston's vibrant Cannonborough/Elliotborough neighborhood. Savor painless access to local eateries, stores, and coffee stores. The...

  • Charleston
  • 3 Bedrooms
  • 3 Bathrooms
  • Sleeps 9
Private Pool & Historic Home - ‘Sugars...

Summary:Adjacent to an iconic Charleston bakery, 'The Sugarsweet House' is a 5 min. walk to famed King Street. This modernized historic home includes a private pool. Savor the modern kitchen, beautiful living & dining area, the serene pool deck, and...

  • Charleston
  • 4 Bedrooms
  • 4 Bathrooms
  • Sleeps 8
Lovely 4BR/2BA Home! Less Than 10 Minute...

Our pretty 4 bedroom/2 bath home is ideally located in the heart of the charming James Island neighborhood. Drive 10 mins. to Downtown Charleston and 8 mins. to Folly Beach. The 1510 square foot single-level home has four bedrooms and two full...

  • Charleston
  • 4 Bedrooms
  • 2 Bathrooms
  • Sleeps 7
Charming Ground Floor Suite 6 Blocks To ...

Summary:Low Tide at Spring Harbor is in the trendy Cannonborough neighborhood, this first-floor duplex unit is ideal for groups of friends or families. It features 3 bedrooms and 2 bathrooms, sleeps up to 6 guests, and includes a private porch for...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 6
Historic Charm & Modern Comfort - Perfec...

Welcome to 12 Cannon Street, Unit B – a charmingly restored two-bedroom, three-bathroom home in the heart of Charleston. This second-floor unit blends historic appeal with modern comfort, offering an ideal getaway for families, couples, and modest...

  • Charleston
  • 2 Bedrooms
  • 3 Bathrooms
  • Sleeps 6
Casa Zoë | Grand Federal Sparrow House ...

Summary:OP2026-07255Sparrow House is a stately Federal-style, National Register residence reimagined for modern group stays. This full-home Casa Zoë gem blends historic appeal—porches, millwork, heart pine floors—with bold, gallery-worthy...

  • Charleston
  • 4 Bedrooms
  • 3 Bathrooms
  • Sleeps 13