Charleston-SC.com logo

2+ Bedroom Vacation Rentals

Filter 2+ Bedroom Properties by: Area | Company | Oceanfront | Pet-Friendly | or choose different Bedrooms
No company options available.
Bedrooms:
1419 rentals found
In the Heart of King Street | Folly Suit...

Permit Number: 004141The Space: Welcome to your second-floor getaway in a attractively restored historic building at iconic 493 King Street—right above Sewing Down South, featured on Southern Charm. Step outside and you’re instantly immersed in...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 6
Ocean View Home in Gated Wild Dunes on G...

Escape to a dreamy Isle of Palms beach vacation at this striking oceanfront four-bedroom vacation rental home located in the highly sought-after and private neighborhood of Ocean Point, located on the northern tip of the Wild Dunes Resort. This...

  • Isle of Palms
  • 4 Bedrooms
  • 3 Bathrooms
  • Sleeps 10
East 42 A & B - Entire Ground Floor, 2 U...

East 42 A & B is the combined listing for the two homes below. These two gorgeous homes can be connected via the fire door in the hallway creating a handsome five bedroom, five bathroom, with a queen murphy bed for flex linens, and two private...

  • Charleston
  • 5 Bedrooms
  • 5 Bathrooms
  • Sleeps 12
New Build, Downtown 3bd Suite w. Porch +...

Summary:Welcome to your Charleston hideaway, a elegantly designed getaway that pairs refined interiors with a calm outdoor space. Ideal for couples, families or modest groups, this property offers the ideal balance of modern comfort and timeless...

  • Charleston
  • 3 Bedrooms
  • 3 Bathrooms
  • Sleeps 8
Chic 2bd Suite w/ Parking, Walk to King!

Summary:Discover Charleston's appeal in this beautiful 2-bed, 1-bath suite near King Street. This private first-floor getaway in a historic duplex blends exposed brick with modern amenities. Featuring two king beds and a couch bed, it comfortably...

  • Charleston
  • 2 Bedrooms
  • 1 Bathrooms
  • Sleeps 5
Charleston Loft | Exclusive Party-Friend...

Step inside Hank’s Loft, a striking Charleston getaway where historic appeal meets modern luxury. With three king bedrooms, en-suite baths, and a private billiard room, every detail invites relaxation. The chef’s kitchen with Viking appliances...

  • Charleston
  • 3 Bedrooms
  • 3 Bathrooms
  • Sleeps 6
Retreat on King Street | Ashley Suite

Permit Number: 004141The Space: Discover The Ashley Suite, a comfortable second-floor unit in historic Charleston at 493 Luxury Suites. Savor a seamless blend of comfort and convenience in this modren getaway.Enter the roomy layout where the...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 6
Only 1 Block to King! | The Sweetgrass

Permit Number: 06474The Space: Welcome to The Sweetgrass House, a roomy two level getaway designed for groups of 8–10 guests looking for comfort, privacy, and an simple downtown Charleston stay. With four bedrooms and four full bathrooms, this...

  • Charleston
  • 4 Bedrooms
  • 4 Bathrooms
  • Sleeps 8
88 Grand Pavilion | AvantStay | Near Bea...

Savor a break from your hectic pace at 88 Grandiose Pavilion. Located on a cozy tree-lined street, this 5 bedroom, 4.5 bath home is a modern beach bungalow that is located in the heart of Wild Dunes. Finest yet, it is only a three-min. walk to the...

  • Isle of Palms
  • 5 Bedrooms
  • 4 Bathrooms
  • Sleeps 12
Sullivans Island condo, centrally locate...

Live like a local and reserve 30 days or more on Sullivans Island! 20 Island House is located in the heart of Sullivans Island just a few steps away from pristine beaches and great eateries. This condo is ideal for an extended hideaway in a trendy...

  • Sullivans Island
  • 2 Bedrooms
  • 1 Bathrooms
  • Sleeps 4
Charleston Guest House- Easy parking! Qu...

Our brand new guest home (constructed in 2019)is a cavernous one bedroom, one bath with a bunk loft. Come savor our peaceful neighborhood after a full day of sightseeing. Located 2 miles from downtown, 10 miles from Folly beach or Sullivan’s...

  • Charleston
  • 2 Bedrooms
  • 1 Bathrooms
  • Sleeps 8
New Ocean View Home: Pool & Putting Gree...

Overview:Welcome to 6 49th Ave - Oak and Ocean! This brand new 5 bedroom; 5 ½ bath home was just finished in January 2026 and is ready for the first lucky guests. The décor is professionally designed with a sophisticated, yet comfortable vibe. The...

  • Isle of Palms
  • 5 Bedrooms
  • 5 Bathrooms
  • Sleeps 12
Home Away From Home- Walkable, Parking &...

Keep it simple and calming at this handsome centrally-located place.Welcome to your Charleston home base! This bright and cavernous 2 bed, 1 bath upstairs apartment features a sizable open living area—ideal for calming, hanging with friends, or...

  • Charleston
  • 2 Bedrooms
  • 1 Bathrooms
  • Sleeps 4
Single Family Downtown House with Privat...

NEW LISTING>> Entire Single Family Home Available for Monthly Units>> Private, Professionally Turfed Backyard>> Prime Location: 2 Blocks to MUSC; Quick Walk to King Street>> 15min Drive to 3 Beaches>> Beds for 6 Guests + 2.5 Bathrooms>> Private...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 6
Gorgeous IOP Home, Second Row, Private P...

Welcome to 4 53rd Avenue on the Isle of Palms, your ideal beach hideaway! This striking 4-bedroom vacation rental is located on the second row from the beach, offering painless beach access—just 50 yards away—and a partial ocean view through the...

  • Isle of Palms
  • 4 Bedrooms
  • 3 Bathrooms
  • Sleeps 10
The Philip's Suite, newly renovated 3 Be...

Welcome to the Philip's Suite (Unit B) at 183 Saint Philip Street, your freshly modernized Charleston haven 1 BLOCK from King Street! This new construction gem places you steps away from the city's vibrant attractions. Each bedroom features Serena ...

  • Charleston
  • 3 Bedrooms
  • 3 Bathrooms
  • Sleeps 8
Renovated - 3 Bed Home - 10 Minutes to D...

**30 Day Rental - $6995/mo!**Discover the ideal blend of convenience and comfort with our James Island rental. Just mins. from historic downtown, pristine beaches, and acclaimed dining, this home offers the best of Lowcountry living while still...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 10
Walk to Hampton Park | Downtown CHS Retr...

Summary:Welcome to a roomy 3-bedroom, 1-bath townhouse getaway! This home offers a prime location in a peaceful neighborhood, ideal for a peaceful stay. The townhouse features central heating and air, ensuring comfort year-round. Savor a completely...

  • Charleston
  • 3 Bedrooms
  • 1 Bathrooms
  • Sleeps 6