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Charleston, SC 2+ Bedroom Vacation Rentals

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1137 rentals found
Historic Charm & Modern Comfort - Perfec...

Welcome to 12 Cannon Street, Unit B – a delightfully restored two-bedroom, three-bathroom home in the heart of Charleston. This second-floor unit blends historic appeal with modern comfort, offering an ideal getaway for families, couples, and...

  • Charleston
  • 2 Bedrooms
  • 3 Bathrooms
  • Sleeps 6
The Bogard House 2BD + Free Parking

Feel the unique beauty of Charleston in this freshly-refreshed two bedroom historic home in the fashionable, laid-back Cannonborough neighborhood. Whether you’re appreciating scrumptious meals at close by eateries, delighting in the historic...

  • Charleston
  • 2 Bedrooms
  • 1 Bathrooms
  • Sleeps 4
Long Term stay in 4-bedroom house in cha...

House available to rent for 3 month interval min. in 2026 beginning January 15, 2026. Located in Charleston, SC, savor all that this 4-bedroom designer home has to offer. With 4 bedrooms and 3.5 baths, guests will have plenty of space to relax. The...

  • Charleston
  • 4 Bedrooms
  • 3 Bathrooms
  • Sleeps 7
Location + Luxury  3BD/3BA - 2 Blocks to...
4.9
(43)

Summary:Welcome to your Charleston luxury getaway, a freshly styled 3-bedroom, 3-bath home that pairs fresh comfort with superb location. Ideal for those who want refined interiors and walk-everywhere convenience, this property sits just two blocks...

  • Charleston
  • 3 Bedrooms
  • 3 Bathrooms
  • Sleeps 6
Charming Condo amongst trees Close to Ev...

Please note: This property is currently listed for sale, so we are discounting the price. If you are comfortable with the occasional showing, Realtor will give you 48 hours before each appointment, you do not have to be present. Stay in a great...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 4
Suite Retreat  on Coming Street ^ Walk E...

Welcome to the Holy City, and the historic southern appeal of the Charleston peninsula. Our Vacation Rental By Owner is located in charming downtown Charleston and just mins. away from MUSC, the College of Charleston, and King Street’s shopping...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 10
Heart of Downtown - All En-suites baths!
4.6
(5)

Summary:Grand groups looking for a authentic, welcoming home away from home in downtown Charleston look no further! Our newly-modernized historic home offers three separate 3 bedroom/3 bath units housed within the same home for a total of 9...

  • Charleston
  • 9 Bedrooms
  • 9 Bathrooms
  • Sleeps 16
Extended Stay Condo with Pool/2mi to Fol...

Summary:Welcome to your ideal coastal stay! This appealing 2-bedroom, 2-bathroom completely furnished rental offers everything you need for a calming 30+ day stay including a pool and just 2 miles from Folly Beach. We offer 2 bicycles for guests to...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 5
A3 at Saint Philip Square, One Block to ...
4.9
(55)

Welcome to Saint Philip Square, an award-winning collection of historic homes spanning nearly one city block in downtown Charleston. The John Bulow House at 174 A St Philip St Unit 3 is a 3-BD 2-BA second floor gem with modern comfort and...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 8
Cozy Townhouse in heart of West Ashley
5.0
(34)

This freshly refreshed townhouse is located in the heart of West Ashley amidst a nice peaceful neighborhood.As you enter you will find a living room with a pretty fireplace, intelligent TV, and a comfortable couch. A full kitchen, washer/dryer...

  • Charleston
  • 2 Bedrooms
  • 1 Bathrooms
  • Sleeps 4
B1 at Saint Philip Square, One Block to ...
4.8
(26)

Welcome to Saint Philip Square, an award-winning collection of historic homes spanning nearly one city block of downtown Charleston. The Adams Bennett House at 174 B#1 Saint Philip Street is a 4-bed 4-bath first floor gem that blends modern comfort...

  • Charleston
  • 4 Bedrooms
  • 4 Bathrooms
  • Sleeps 10
Charming 2-bedroom house in beautiful Ch...

Escape to this newly refreshed duplex in striking Charleston. With 2 queen beds, a completely supplied kitchen, washer/dryer, heating + AC, guests will have everything they need for a ideal stay. 10 mins. from downtown and the airport, close to...

  • Charleston
  • 2 Bedrooms
  • 1 Bathrooms
  • Sleeps 4
Soho House | Prime Location, Walk to Eve...
5.0
(47)

Summary:Step into a classic Charleston getaway designed for guests who want history, comfort and convenience in one. This home is ideal for couples, families or modest groups looking to savor walkability, appeal and painless access to the city’s...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 10
Quiet Retreat in Downtown Charleston –...
3.9
(9)

The Coach House – Historic Charm & Cozy Living in Downtown CharlestonTucked behind the Wickliffe House in the heart of Charleston's medical district, The Coach House is a 3-bedroom, 3-bath home offering timeless character and refreshed comfort in...

  • Charleston
  • 3 Bedrooms
  • 3 Bathrooms
  • Sleeps 6
The Sunsetter | Only 1 block to King!
4.4
(15)

Permit Number: 05933The Space: This is a classic Charleston Home. When you drive up to this property chances are you will say, one thing, “Wow”. The location by Saint Phillip and Morris streets is just one block over from King Street’s most...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 7
Private Rooftop + Parking - 3 Blocks to ...
5.0
(28)

Welcome to Rosé Getaway!Notable amenities include :- Private Rooftop Deck!- 3 Blocks to King St – Walk to Charleston’s Finest Dining, Shopping & Nightlife- On-Site Parking for 1 Car- Cozy Mattresses- Intelligent TVs – Streaming Included!...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 8
8C at Saint Philip Square, One Block to ...
5.0
(37)

Welcome to Saint Philip Square, an award-winning collection of historic homes spanning nearly one city block of downtown Charleston. The Alexander Wilson House at 178 Unit C Saint Philip St. is a 3-bed 4-bath gem blending modern comfort with...

  • Charleston
  • 3 Bedrooms
  • 4 Bathrooms
  • Sleeps 8
THE INNS Amazing 2 BR  1 BA Luxury Suite...
4.8
(15)

Summary:Stay in this professionally designed 2-bedroom, 1-bath luxury suite in downtown Charleston, just two blocks from King Street. With modren finishes, a completely equipped kitchen, and handsomely styled décor, it blends elegance and comfort...

  • Charleston
  • 2 Bedrooms
  • 1 Bathrooms
  • Sleeps 6