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Charleston, SC 2+ Bedroom Vacation Rentals

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1064 rentals found
8 Bedroom - Close to King Street - with ...

Feel the timeless appeal of Charleston’s historic peninsula, the Holy City. Stay just mins. from MUSC, the College of Charleston, and the vibrant shopping, dining, and nightlife of King Street. From this ideally located downtown home, you’ll be...

  • Charleston
  • 8 Bedrooms
  • 4 Bathrooms
  • Sleeps 16
The Chapel | Premier 13BR Estate in Down...

Summary:Welcome to The Chapel, a majestic 13-bedroom estate in downtown Charleston where beauty, space and heritage combine to create an memorable stay. Ideal for huge families, weddings, get-togethers or special gatherings, this property offers...

  • Charleston
  • 13 Bedrooms
  • 12 Bathrooms
  • Sleeps 16
The Bogard House 2BD + Free Parking

Feel the unique beauty of Charleston in this freshly-remodeled two bedroom historic home in the trendy, laid-back Cannonborough neighborhood. Whether you’re appreciating scrumptious meals at close by eateries, delighting in the historic sights and...

  • Charleston
  • 2 Bedrooms
  • 1 Bathrooms
  • Sleeps 4
The Monroe | 5BR - Voted Best of Charles...

Summary:Stay at The Monroe on Spring, a completely modernized 1885 Charleston manor voted Finest of Charleston. Blending historic grandeur with modern luxury, this 5-bedroom getaway features handsome interiors and sprawling porches ideal for calming...

  • Charleston
  • 5 Bedrooms
  • 5 Bathrooms
  • Sleeps 16
NEW! Close To Downtown Charleston And Be...

Come experience Charleston while staying in this ideally styled new build. 4 miles to Downtown Charleston with award winning eateries, striking nighttime life, and historic beauty. Centrally located to Folly Beach and Sullivans Island Beach, both...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 6
The Savannah at The Conroy

Permit Number: BL049129-09-2026The Space: Located on the third floor of The Conroy, this delightfully remodeled 2-bedroom, 2.5-bath residence blends historic Charleston character with elevated modern comfort. Thoughtfully and gorgeously designed...

  • Charleston
  • 2 Bedrooms
  • 3 Bathrooms
  • Sleeps 6
Beautifully Restored 3-Bedroom Home with...

26 Bee Street Unit A is a beautiful three-bedroom, three-bathroom home, offering a sunny and inviting ambiance throughout. The main floor features an open-concept living, dining, and kitchen area, ideal for calming or entertaining. Just off the...

  • Charleston
  • 3 Bedrooms
  • 3 Bathrooms
  • Sleeps 6
The Hampstead Suite- Free Parking & Walk...

Occupying the entire upper level of a historic duplex, this roughly 1,000-square-foot residence offers a cavernous and comfortable layout designed for calming after a day of exploring the city. Guests will savor a bright living room, entirely...

  • Charleston
  • 3 Bedrooms
  • 3 Bathrooms
  • Sleeps 6
The Cannonball Suite | 1 Block to King S...

Permit Number: 05279The Space: Welcome to The Cannonball Suite, a attractively modernized getaway occupying an entire classic Charleston Single home and designed for a chic downtown stay!This colorful, thoughtfully designed space blends historic...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 4
Stylish Haven in Historic CHS! | Petunia...

Permit Number: 07042The Space: Welcome to Petunia Suite, your modren 2-bedroom, 2-bath getaway on Rutledge Avenue in the heart of downtown Charleston!This newly refreshed apartment blends a bright open layout with mid-century modern style and...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 5
Charleston Home near Downtown & Folly Be...

FULLY REMODELED HOME IN 2023. BRAND NEW AC UNIT INSTALLED IN 2021. This is a comfortable and cozy brick ranch on James Island that is 10-15 mins. from Folly Beach and 10-15 mins. from Downtown Charleston. ($10 Uber ride). Spend time in this amazing...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 8
A3 at Saint Philip Square, One Block to ...

Welcome to beautiful Saint Philip Square, a collection of 5 historic homes spanning nearly a city block of downtown Charleston. 174 Unit A#3 Saint Philip St. is a classic 3BD/2BA upstairs unit blending modern amenities and historic appeal. Just a...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 8
60' Sailing Yacht on a Private Dock

There's simply nothing else like it in Charleston!300 yards down a private road and you're in the middle of the beautiful marsh. Just you, dolphins, birds, the occasional kayaker...and of course this big sailing yacht. The three well-appointed...

  • Charleston
  • 3 Bedrooms
  • 1 Bathrooms
  • Sleeps 5
Tradition with a Modern Twist | The Prim...

Permit Number: 07282The Space: This impressive secondfloor 2-bedroom, 1-bath home is located inside a historic Charleston residence constructed in 1835, blending classic character with modern comfort in the heart of downtown!Inside you’ll...

  • Charleston
  • 2 Bedrooms
  • 1 Bathrooms
  • Sleeps 4
Casa Zoë | Elegant 3BR Retreat Near Kin...

Summary:OP2026-07256Palmetto Cottage is a signature Casa Zoë stay—effortlessly beautiful, light-filled, and ideally placed. With three ensuite bedrooms, open living spaces, and a handsomely appointed kitchen, it’s designed for simple...

  • Charleston
  • 3 Bedrooms
  • 3 Bathrooms
  • Sleeps 8
2 Bedroom Great Location - Close to King...

Feel the timeless appeal of Charleston’s historic peninsula, the Holy City. Stay just mins. from MUSC, the College of Charleston, and the vibrant shopping, dining, and nightlife of King Street. From this ideally located downtown home, you’ll be...

  • Charleston
  • 2 Bedrooms
  • 1 Bathrooms
  • Sleeps 6
Poolside Palmetto Retreat-Charleston 3 B...

Welcome to your ideal Lowcountry hideaway! Located on a peaceful cul-de-sac in North Charleston, this elegantly remodeled 3-bedroom, 2.5-bath entire home offers ample sleeping space for families, friend groups, and gatherings—conveniently located...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 10
6A at Saint Philip Square, One Block to ...

Immerse yourself in Southern luxury and appeal at Saint Philip Square. Our award-winning collection of historic homes spans nearly one city block. Located in the heart of historic Charleston and just one block from King Street,The Aiken House, unit...

  • Charleston
  • 3 Bedrooms
  • 3 Bathrooms
  • Sleeps 8