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Charleston, SC 2+ Bedroom Vacation Rentals

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1052 rentals found
Historic, newly renovated, 1 block off u...

Located in the heart of the historic district. 1 block off of upper King Street. Everything is a convenient walk...to great eateries, museums, music, Marion square, MUSC hospital....Home was originally constructed in 1906 and newly entirely...

  • Charleston
  • 2 Bedrooms
  • 1 Bathrooms
  • Sleeps 4
Cozy Haven, Close to Charleston's Best |...

Permit Number: 06609The Space: Indulge in the appeal of the Holy City at The Elton, a warm and welcoming second floor condo designed for couples, friends, or families of up to four guests!Bedrooms & Bathrooms• Primary bedroom with a comfortable...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 5
Experience Folly Life & Water Views Quie...

Quiet top floor condo located between two bridges with spectacular saltwater tidal vistas located on a friendly neighborhood road. One mile to the Folly Beach and only ten miles to Downtown Charleston. Unwind after a day at the beach on the outdoor...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 4
Updated Pet-Friendly Home Near Park Circ...

Summary:Hanahan HideawayThe Space:Welcome to Hanahan Hideaway, a gorgeously refreshed three-bedroom, two-bath home with a fresh, light, and airy interior, thoughtfully designed to host up to six guests. Tucked into a impressive neighborhood, this...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 6
Historic Downtown Family Friendly Spacio...

Summary:Fauna House, a home constructed in 1905, features 4 cavernous bedrooms and 2 bathrooms, enhanced with relaxing green and blue accents that create a fresh, inviting ambiance. Bare brick fireplaces serve as striking focal points within the...

  • Charleston
  • 4 Bedrooms
  • 2 Bathrooms
  • Sleeps 8
Edisto House | Great for Group Stays | N...

Summary:Welcome to Edisto House, a bright first floor 2 BR / 2 BA condo with four beds, and a sleeper couch, making it ideal for huge groups. Located only half a block off upper King, you are steps from Charleston's best eateries, stores, and...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 6
Ivory Loft Downtown, Close to Shops & Re...

Summary:Welcome to The Ivory Loft, a chic 4-bedroom, 3-bathroom lower level unit located in the heart of Downtown Charleston. This thoughtfully designed space blends modern aesthetics with artistic flair, offering a comfortable and unique getaway...

  • Charleston
  • 4 Bedrooms
  • 3 Bathrooms
  • Sleeps 8
Rutledge Ave - Renovated 2 Bed Home - Do...

Feel the timeless appeal of Charleston’s historic peninsula, the Holy City. Stay just mins. from MUSC, the College of Charleston, and the vibrant shopping, dining, and nightlife of King Street. From this ideally located downtown home, you’ll be...

  • Charleston
  • 2 Bedrooms
  • 1 Bathrooms
  • Sleeps 6
Pet-Friendly +Historic Charm & Modern Co...

Map House – Historic Charm Meets Modern Luxury in Downtown CharlestonJust blocks from the lively Upper King District, Map House is a handsomely restored 3-bedroom, 2-bathroom Charleston Single home with double piazzas, original architectural...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 6
Large, Historic 6BR, Designed to Perfect...

Summary:Welcome to Palmetto Hideaway, a striking 6-bedroom designer home in the heart of downtown Charleston. Ideal for huge families, friend getaways, or anyone who craves style, space, and character, it immerses you in history while offering...

  • Charleston
  • 6 Bedrooms
  • 6 Bathrooms
  • Sleeps 16
Cooper River Cottage

This home is just a 10-min. walk from Downtown Charleston and the Cooper River. This comfortable home offers well-furnished living spaces, a full kitchen, and cozy bedrooms. You’ll be near King Street’s stores, eateries, and galleries, with...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 6
Manhattan Suite-Where Luxury and Locatio...

Location, Location, Location! One of Charleston's most fantastic addresses. This impressive unit is located in one of the most ideal locations in all of Charleston. Please watch the video(Unit A). We are located 100 yards from the freshly...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 4
New Charleston meets Old Charleston!

https://youtu.be/yoy7_cTP81w Video Link to U-tube PageFirst time on the Vacation Rental By Owner market! This gorgeous monthly rental home is located in the French Quarter in a rather residential area called the Exchange, for its proximity to...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 6
Casa Zoë | Cottage Row – Side-by-Side...

Summary:OP2025-05857OP2025-05858Cottage Row is a rare Charleston find with two completely separate, next-door Casa Zoë cottages that together create the ideal setup for groups who want to be close but still have their own space. Tucked in the...

  • Charleston
  • 4 Bedrooms
  • 4 Bathrooms
  • Sleeps 10
The Cannon Exchange Building By Charlest...

Feel the pinnacle of Charleston living at the Cannon Exchange Building, a thoughtfully designed luxury property offering two broad residences: The Chateau and The Soirée. Each unit accommodates up to 14 guests, making the building ideal for huge...

  • Charleston
  • 10 Bedrooms
  • 11 Bathrooms
  • Sleeps 28
Two Bedroom House Downtown.

This home is near MUSC. There are many neighborhood eateries. It is a very close walk to King Street that has tons of shopping. The home has off street parking. The home Is 2 bedrooms with 1 bathroom. The kitchen and living room is one big room. The...

  • Charleston
  • 2 Bedrooms
  • 1 Bathrooms
  • Sleeps 4
Adorable Family Home With Heated Pool

Summary:Come stay at our newest addition, and appreciate the serenity that our striking property has to offer.The Space:This cute 3 bedroom, 3 1/2 bath home is great for family vacations, guys' golf trips, or even girls' weekend getaways. Sit and...

  • Charleston
  • 3 Bedrooms
  • 3 Bathrooms
  • Sleeps 8
 Upscale House, King Beds, Private Baths...

Your Charleston adventure begins at this enchanting 4-bedroom home.Stay Cannon is a legally allowed vacation rental as required by Charleston City Ordinance and is located in the trendy Cannonborough/Elliotborough neighborhood. Our license number is...

  • Charleston
  • 4 Bedrooms
  • 4 Bathrooms
  • Sleeps 10