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Isle of Palms, SC 2+ Bedroom Vacation Rentals

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1404 rentals found
4 Bedroom - 2 Blocks to King Street!

Feel the timeless appeal of Charleston’s historic peninsula, the Holy City. Stay just mins. from MUSC, the College of Charleston, and the vibrant shopping, dining, and nightlife of King Street. From this ideally located downtown home, you’ll be...

  • Charleston
  • 4 Bedrooms
  • 2 Bathrooms
  • Sleeps 12
The Inns | Grand 9BR Home in Downtown | ...

Summary:Welcome to your Charleston getaway, a huge 9-bedroom haven designed for groups who value space, style, and connection. Recently refreshed with fresh paint, brand-new beds, and crisp linens, this luxury mansion offers two full kitchens, six...

  • Charleston
  • 9 Bedrooms
  • 6 Bathrooms
  • Sleeps 16
Fun Beach House

Savor the best of Sullivan's on the peaceful end of the Island. Appreciate peeks of the inter-coastal way, home is 3 blocks to the beach and walking distance to eateries, playground and tennis courts. A cavernous screen porch, loads of natural...

  • Sullivans Island
  • 3 Bedrooms
  • 3 Bathrooms
  • Sleeps 6
Sweetgrass (Suite A) | Blocks from King ...

Permit Number: 06474The Space: Our roomy 1st floor condo, ‘Sweetgrass A’, is ideal for groups of 4 guests with 2 bedrooms, 2 full baths. Located just off of Spring Street, location and parking won't be an issue here!Accessed by it own...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 4
The Pineapple Pad | EastBay Historic Dis...

Summary:Welcome to your Charleston sanctuary where historic appeal meets roomy luxury. This 5-bedroom getaway offers a generous 3,000 square feet of delightfully appointed space. Ideal for families or groups who want handsome design, room to spread...

  • Charleston
  • 5 Bedrooms
  • 4 Bathrooms
  • Sleeps 16
Casa Fuego - D  | Walk to the Best Resta...

Permit Number: 06049The Space: Welcome to Casa Fuego (Suite D)! Located on the ground floor of a traditional Charleston Single home, this freshly remodeled condo is the ideal jumping off point for your visit. This space includes 2 bedrooms, 1...

  • Charleston
  • 2 Bedrooms
  • 1 Bathrooms
  • Sleeps 5
The Gardenia House | Sleeps 15 | Multi-U...

Summary:Welcome to the Gardenia House in the Preserve, a distinguished luxury residence located in the heart of downtown Charleston. This chic property offers two exclusive suites within a cavernous layout of 7 bedrooms and 7 full baths, making it...

  • Charleston
  • 7 Bedrooms
  • 7 Bathrooms
  • Sleeps 15
New! Lovely House 3BR in Charleston

Totally modernized home 3 bedrooms, 2 bathrooms and 1 huge office located in West Ashley, peaceful neighborhood! Excellent location to accessing beaches, just 5 mins. away from Roper hospitals, tons of eateries, and 5 mins. from Gym Health Club...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 6
Private Backyard With Fire Pit, 15 Min t...

Welcome to this newly remodeled guesthouse in the heart of West Ashley. While staying in this adorable 850 sqft. home, you'll fall in appreciate with the newly redone kitchen featuring a comfortable breakfast nook. You'll also appreciate: Deck with...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 4
SEAGROVE Villa - The Place To Be in Wild...

Hidden among lush, tropical foliage and majestic live oaks are the handsomely landscaped Seagrove Villas. Just steps from the ocean, this modern 2 bedroom villa is the ideal place for families to reconnect or couples to getaway. Waiting for you are...

  • Isle of Palms
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 6
Drayton Suite | In the Heart of King Str...

Permit Number: 004141The Space: Welcome to 493 Luxury Suites!This attractively appointed second-floor unit sits in a historic building right on King Street—above Sewing Down South, as seen on Southern Charm. The location places you in the heart of...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 6
120 Seascape Villas - Newly Renovated

Welcome to Sunny Daze, a freshly refreshed 3-bedroom, 3-bathroom oceanfront condo located on the handsome Wild Dunes beaches of Isle of Palms. Updates include brand-new living room furnishings, updated bathrooms, and fresh floor and paint...

  • Isle of Palms
  • 3 Bedrooms
  • 3 Bathrooms
  • Sleeps 6
Kings Corner- Entire Historic Charleston...

Welcome to King`s Corner- An entire 2-story, 4 bedroom, 5 and a half bathroom, historic Charleston home in Downtown Charleston, just off King Street!This newly remodeled historic home provides all the modern amenities you need in downtown...

  • Charleston
  • 4 Bedrooms
  • 6 Bathrooms
  • Sleeps 12
Spacious area- Private 2 brs, 2 baths

City of Charleston Certificate of Operation Permit # OP2024-056251st floor of a duplex. 1250 SF. The bedrooms (and full bathrooms) are located on opposite sides of the single floor unit . Extensive living room, fireplace , intelligent tv with...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 4
Steps to Beach & Pool | Screened Porch |...

Welcome to 45 Pelican Bay by AvantStay!Step into the casual rhythm of coastal living at 45 Pelican Reach, a elegantly refreshed getaway tucked within the gated Wild Dunes Resort on Isle of Palms. Just a short walk to the beach and moments from the...

  • Isle of Palms
  • 3 Bedrooms
  • 3 Bathrooms
  • Sleeps 8
Prime Grand Pavilion Location! Steps fro...

Located in the heart of Wild Dunes Resort and just steps from the Atlantic Ocean, this special oceanfront home is the ideal spot for an Isle of Palms vacation! This gem is a 4 bedroom, 4 bathroom home located directly on the fashionable Grandiose...

  • Isle of Palms
  • 4 Bedrooms
  • 4 Bathrooms
  • Sleeps 10
Spacious 3 bedroom with pool in quiet ne...

Bring the whole family to this great home with tons of room for fun, yet still find space for private time. It's our home away from home, so make it yours. Shopping galore near the Citadel Mall, and eateries at every corner. Golf and beaches within...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 8
Beautiful Home on the Water

3000 sqft 3Bedrooms 4Bathrooms Property type Waterfront Living- Close to I-526 and Downtown Charleston Secluded Neighborhood Enormous Garage Space Close to Eateries, Stores, & Mall KEY FEATURES Parking: Garage Property Type: Single Family House This...

  • Charleston
  • 3 Bedrooms
  • 3 Bathrooms
  • Sleeps 14