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Charleston, SC 4+ Bedroom Vacation Rentals

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346 rentals found
Explore Downtown King St - 12 Bedrooms/7...

Summary:Welcome to your Charleston showcase, a grandiose 12-bedroom, 7.5-bath estate located right in the heart of downtown just off King Street. Designed for sizable groups, corporate retreats, or family gatherings, this property blends scale...

  • Charleston
  • 12 Bedrooms
  • 7 Bathrooms
  • Sleeps 16
Luxurious Waterfront Getaway, minutes fr...

This Waterfront, 5 Bedroom / 5 Bathroom home on Oak Island is 100% gut modernized, mins. from Folly Beach and is the ideal hideaway for families and friends. All bedrooms have king size beds. The home features two kitchens both completely...

  • Charleston
  • 5 Bedrooms
  • 5 Bathrooms
  • Sleeps 8
Historic Whole Home- Private Heated Pool...

Summary:Welcome to Your Private Oasis in Historic Charleston!Feel the ideal fusion of Historic appeal and modern luxury at this five-bedroom, three-and-a-half-bathroom Historic Home. Located just blocks from the iconic King Street, this residence...

  • Charleston
  • 5 Bedrooms
  • 3 Bathrooms
  • Sleeps 14
La Maisonette Du Angeline | Revival St C...

Summary:La Maisonette d' Angeline is a part of the Revival Street Collection - a curated group of historic homes constructed in the early 1900s and thoughtfully 'revived' from their Victorian-era origins. Located just above one of our favorite...

  • Charleston
  • 4 Bedrooms
  • 3 Bathrooms
  • Sleeps 9
Bee & Blossom | Historic Charm

Permit Number: 06191The Space: This former historic Bed and Breakfast has undergone a magical transformation into what is a newly-modernized 6 bedroom/6.5 bath designer's showcase home in the trendy, laid-back Radcliffborough neighborhood. Close to...

  • Charleston
  • 6 Bedrooms
  • 6 Bathrooms
  • Sleeps 12
Guesthouse Charleston: WEST (242 B)

West 242 B is a striking standalone home located in the heart of the Cannonborough/Elliotborough neighborhood, just two blocks from historic King Street. This prime downtown Charleston location offers simple access to the best eateries, coffee...

  • Charleston
  • 4 Bedrooms
  • 3 Bathrooms
  • Sleeps 8
The Mary Scott and Daniel Legare House

Permit Number: 05793The Space: Welcome to your Charleston getaway at 11 George Street! This striking and cavernous home features 6 charmingly appointed bedrooms and 3 bathrooms, ideal for accommodating huge groups or families.The sleeping...

  • Charleston
  • 5 Bedrooms
  • 3 Bathrooms
  • Sleeps 16
The King Suites at 493 - 8 Suites, 16 Be...

Permit Number: 004141The Space: Welcome to 493 Luxury Suites! These elegantly appointed units are found on the second floor of a historic building on King Street (above Sewing Down South, as seen on “Southern Charm”).Step into the building...

  • Charleston
  • 16 Bedrooms
  • 16 Bathrooms
  • Sleeps 52
Huge 5-bedroom home in the heart of down...

This cavernous 5-bedroom, 3-bathroom historic home offers a unique blend of Southern appeal and modern comfort. Located in the heart of Downtown Charleston, you'll be within walking distance of the city's best eateries, vibrant bars, and captivating...

  • Charleston
  • 5 Bedrooms
  • 3 Bathrooms
  • Sleeps 13
Elegant & Modern Home in Downtown Charle...

Summary:Welcome to your Charleston hideaway, where modern design meets Southern appeal. This handsome downtown home is designed with comfort and style in mind, offering the ideal getaway for families, friends, or business travelers looking to...

  • Charleston
  • 4 Bedrooms
  • 4 Bathrooms
  • Sleeps 15
Spacious 4BR Retreat w/ Huge Yard, Outdo...

Cavernous 4BR home (2x King, 2x Queen) just 12 mins. from Folly Beach and 8 mins. to downtown Charleston. Savor a giant fenced yard, outdoor shower, fire pit, and a enormous dining table with umbrella and fan—ideal for warm evenings. Located under...

  • Charleston
  • 4 Bedrooms
  • 2 Bathrooms
  • Sleeps 8
Fantastic Private Quarters in Heart of D...

Summary:Here you can live by calming both indoors and outdoors.The Space:Summons the expression of really refined Ante-Bellum experience with all modern amenities. In the kitchen appreciate the timeless La CornueFe gas oven and cooktop range from...

  • Charleston
  • 5 Bedrooms
  • 3 Bathrooms
  • Sleeps 10
The Tropic - Large Jungly Oasis, Great f...

Welcome to the Tropic! Private single-family home with huge screened-in porch and jungly backyard less than 10 mins. to downtown and 15 to beach. Walkable to coffee stores, bars and dining. Outdoor dining, grille and deck, tropical plants, a work...

  • Charleston
  • 5 Bedrooms
  • 2 Bathrooms
  • Sleeps 12
The Inns | Luxury Design w. Speakeasy Ba...

Summary:Surrounded by swaying Spanish moss in one of Charleston’s most striking neighborhoods, this gorgeous 7-bedroom, 5-bath home captures the essence of Southern grace with a modern twist. Thoughtfully remodeled in September 2025, every detail...

  • Charleston
  • 7 Bedrooms
  • 5 Bathrooms
  • Sleeps 14
Revitalized Historical Southern Residenc...

Summary:Ideal for a huge family! Just one block away from upper King Street, the new epicenter of the city's acclaimed restaurant and nightlife district. Appreciate some of Charleston's best local dining, all located within just a few blocks of the...

  • Charleston
  • 4 Bedrooms
  • 3 Bathrooms
  • Sleeps 10
Modernized 5BR Family Home?Tranquil Pati...

This handsome 5-bedroom, 2.5-bathroom home is a true gem, located on one of the quietest streets in Charleston. With freshly refreshed bathrooms, resurfaced floors, and a cavernous, open floor plan, this home is ideal for families or professionals...

  • Charleston
  • 5 Bedrooms
  • 3 Bathrooms
  • Sleeps 10
Guesthouse Charleston: WEST 62 & 64

West 62 and 64 are two striking homes located next door to each other, sharing a cavernous outdoor courtyard ideal for calming with drinks after a day of exploring Charleston. Each home offers generous living spaces, huge bedrooms, and multiple...

  • Charleston
  • 10 Bedrooms
  • 9 Bathrooms
  • Sleeps 24
Ivory Loft Downtown | Close to Shops & R...

Summary:Welcome to The Ivory Loft, a chic 4-bedroom, 3-bathroom lower level unit located in the heart of Downtown Charleston. This thoughtfully designed space blends modern aesthetics with artistic flair, offering a comfortable and unique getaway...

  • Charleston
  • 4 Bedrooms
  • 3 Bathrooms
  • Sleeps 8