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Charleston, SC 2+ Bedroom Vacation Rentals

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1068 rentals found
The Grand Helène - Newly Renovated 11BD...

Summary:Freshly constructed 11BR/11.5BA home in the laid-back Cannonborough/Elliotborough neighborhood—ideal for huge groups seeking space and privacy. The property features three separate units in one building, ideal for gathering together while...

  • Charleston
  • 11 Bedrooms
  • 12 Bathrooms
  • Sleeps 22
The Crescent Moon - Walk to King

Come savor this revamped 2 bedroom 2 bathroom apartment centrally located on the Charleston peninsula. Take a short walk to King Street to appreciate a meal at one of Charleston’s many world acclaimed eateries, or take advantage of the well...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 6
New Charleston meets Old Charleston!

https://youtu.be/yoy7_cTP81w Video Link to U-tube PageFirst time on the Vacation Rental By Owner market! This beautiful monthly rental home is located in the French Quarter in a rather residential area called the Exchange, for its proximity to...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 6
The Inns - 2BR / 2BA - Downtown Gem!

Summary:Located on gorgeous Spring Street, this beautiful 2-bedroom, 2-bath getaway embodies the essence of historic Charleston living. Bright and airy with high ceilings and timeless character, it features a completely outfitted kitchen ideal for...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 4
Welcome to this adorable well maintained...

Ideal located home, 5 mins. from Folly and 10 mins. from downtown Charleston and MUSC. Home has been newly furnished; adore shown in all the details.This 1,864 square feet home is a calming space for the business professional or traveling...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 5
NEW! Historic, Professional Decorated 2 ...

190 St. Philip Street is a traditional Charleston home located just one block to King Street. The main floor has an open living room adjoining the bright kitchen complete with open shelving and a bespoke banquet. Upstairs there are two bedrooms with...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 6
Cozy 4bd Home with Porch, Near King Stre...

Summary:Welcome to your cavernous Charleston getaway, where modern remodel meets classic appeal. This rare 6-bedroom home is made up of two completely equipped units rented together, offering the ideal setup for families or groups who want both...

  • Charleston
  • 4 Bedrooms
  • 2 Bathrooms
  • Sleeps 10
The Manor by Guesthouse Charleston- Gran...

91A Spring Street is a delightfully restored Victorian Home. This home has 4 bedrooms and 4.5 bathrooms a sizable open living, dining, and kitchen area that opens up to roomy front porches that overlook the piazza. Each bedroom has a private ensuite...

  • Charleston
  • 4 Bedrooms
  • 4 Bathrooms
  • Sleeps 10
Central Location. Hot Tub! Aqua Terra Co...

Savor a beautiful experience at this centrally-located home. Escape to our classy mid-century bungalow, ideally located for your next hideaway! Ideal for girls’ trips, couples, or families, this chic boho getaway invites you to vacation like a...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 6
Cozy Cottage • Near Downtown

Tucked away on a peaceful street, our gorgeous home is close to anywhere you want to go in Charleston! A short 14 mile trip to the beach and just 15 min to King Street, and Charleston’s International Airport.

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 8
Stylish 3bd House with Parking + Outdoor...

Summary:Discover The Copper, a fresh 3-bed, 2-bath Charleston getaway just one block from vibrant Upper King Street. Ideal for groups or families, this bright, modern home offers a dedicated workspace, a completely equipped kitchen, and off-street...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 5
1905 Victorian Historic Home Just 2 Bloc...

Summary:Stay at our impressive 1905 Charleston Victorian home in the heart of Cannonborough. Just 2 blocks from King Street, this property features nearly 1850 square feet of ideally designed space. The front home offers 4 full-sized bedrooms with...

  • Charleston
  • 4 Bedrooms
  • 3 Bathrooms
  • Sleeps 8
Luxury Two Bedroom Residence with Outdoo...

The Pinch Hotel offers completely outfitted guestrooms, luxury amenities from check-in to check-out, and an ambiance of warmth and surprise, The Pinch is a touch of high culture in the Lowcountry. Let us redefine what a luxury, boutique hotel can...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 4
The Inns | 18 bedrooms, Luxurious + Gran...

Summary:As part of the esteemed collection, The Inns, this impressive 18-bedroom compound is located on Spring Street in the heart of Charleston. Ideal for sizable groups, this completely modernized property combines two handsome Victorian homes...

  • Charleston
  • 18 Bedrooms
  • 14 Bathrooms
  • Sleeps 30
A Locals Hotspot! | The Globetrotter

Permit Number: 05139The Space: Welcome to The Globetrotter House, a roomy and welcoming Charleston home ideal for groups of 8–11 guests. Located just off Spring Street, this thoughtfully designed getaway offers 4 bedrooms and 4 full bathrooms...

  • Charleston
  • 4 Bedrooms
  • 4 Bathrooms
  • Sleeps 9
Downtown 2 bedroom, 2 bath, pet friendly...

******Please note this unit is for sale. Honey Bee, one of Charleston's Finest, is a 2 bedroom 2 bath freshly refreshed apartment in the heart of historic downtown Charleston. It is available for units of 30 days or longer. It is the ideal home away...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 4
New! Private Home Downtown at Emerson Sq...

Summary:Brand new Home in the heart of downtown Charleston. This Professionally designed private residence offers a warm and inviting aesthetic, with a enormous 3rd floor primary suite featuring a bespoke constructed king size bed and a roomy...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 6
Wilhelmenia Queen 2BR | Walk to King | S...

Summary:Welcome to The Queen of Wilhelmenia's, a beautiful and cavernous rental just two blocks from King Street in the heart of the city. This second floor hideaway features two bedrooms and one bathroom, ideal for families, groups, or business...

  • Charleston
  • 2 Bedrooms
  • 1 Bathrooms
  • Sleeps 6