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Charleston, SC 2+ Bedroom Vacation Rentals

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1069 rentals found
2BR Suite in Gorgeous Antebellum Mansion

Summary:This impressive home features restored antique heart pine floor, tongue and groove walls, with original European hardware. Fixtures like the imported La Cornue gas range and big Green Egg grille add the final modern touches. Walkable to...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 4
Rose Suite: Timeless Comfort only 5 Bloc...

Permit Number: 06089The Space: Located in the heart of downtown Charleston, our freshly remodeled 2-bedroom, 2-bathroom apartment at the Rose Suite is designed to cater to all your travel desires. Step into a luminous, open layout adorned with a...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 5
Elegant Downtown Charleston - 2 Bedroom ...

Summary:Welcome to your downtown Charleston getaway, an opulent 2-bedroom, 2-bath home that blends serenity, style, and walking proximity to the city’s best. Ideal for couples or modest groups seeking refined comfort, natural light, and a location...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 5
Stay in style in this unique 2Bed/1Bath ...

Stunning, artistic first floor apartment in a historic 1920’s Charleston single home located in the heart of one of the city’s most beloved neighborhoods. It's a stone's throw away from idyllic Hampton park and a short walk to many of...

  • Charleston
  • 2 Bedrooms
  • 1 Bathrooms
  • Sleeps 4
 New Upscale 4 Bedroom, King Beds , Priv...

Your Charleston adventure begins at this enchanting 4-bedroom home.Stay Cannon is a legally allowed vacation rental as required by Charleston City Ordinance and is located in the fashionable Cannonborough/Elliotborough neighborhood.Great for family...

  • Charleston
  • 4 Bedrooms
  • 4 Bathrooms
  • Sleeps 10
The Barbados House | Luxury House | Slee...

Summary:Welcome to the Barbados House, part of The Preserve, a luxury single-style home located in the heart of downtown Charleston. This elegant 5-bedroom, 5.5-bath residence offers an unparalleled blend of sophisticated appeal and modern comfort...

  • Charleston
  • 5 Bedrooms
  • 5 Bathrooms
  • Sleeps 12
Historic Charleston Style House ?

Summary:Step into this elegantly preserved Charleston-style home where old-world appeal meets modern comfort. Ideal for couples, families, or modest groups, it offers a welcoming getaway filled with character in a prime location. Located in a...

  • Charleston
  • 3 Bedrooms
  • 1 Bathrooms
  • Sleeps 9
Boho Ferry- Mins from Credit One- Pet Fr...

Summary:Welcome to Boho Ferry. This classy 2-bedroom, 2.5-bathroom home comfortably sleeps up to 4 guests with two king sized beds. Just mins. from Credit One Stadium and Shipyard Park, and only 15 mins. to historic downtown Charleston. The beach is...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 4
The Inns | Luxury Design w. Speakeasy Ba...

Summary:Surrounded by swaying Spanish moss in one of Charleston’s most photogenic neighborhoods, this impressive 7-bedroom, 5-bath home captures the essence of Southern grace with a modern twist. Thoughtfully modernized in September 2025, every...

  • Charleston
  • 7 Bedrooms
  • 5 Bathrooms
  • Sleeps 14
The Manor 93 - B Beautiful Three Bed Thr...

The Manor 93 B is a elegantly designed 1880's Charleston home offering 3 en-suite bedrooms, an open living room, and a patio ideal for alfresco dining. Only 2.5 blocks to King St, with stores, eateries, and landmarks like the Battery and Market all...

  • Charleston
  • 3 Bedrooms
  • 3 Bathrooms
  • Sleeps 6
? The Inns ? Charming Suite | Courtyard ...

Summary:Stay in this striking suite tucked away in a serene Charleston courtyard with secured private parking. Featuring soft lighting, charming furnishings, and calming garden vistas this comfortable space invites relaxation. Walk to close by...

  • Charleston
  • 2 Bedrooms
  • 1 Bathrooms
  • Sleeps 6
Chic downtown condo. Walk to everything!

Luxury Urban Loft with Stunning Park Vistas & Rooftop RetreatStep into fresh city living with this roomy 2-bedroom, 2-bathroom loft in an environmentally friendly, LEED Certified complex. This light-filled home features soaring 10-foot ceilings and...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 5
The Palmetto | Rooftop Deck, Perfect for...

Summary:Feel Charleston living in this freshly refreshed 4BR/4.5BA getaway, ideal for friends or families. Located in the laid-back Cannonborough neighborhood, you’ll be steps from vibrant dining, rich history, and local appeal. Just 3 blocks from...

  • Charleston
  • 4 Bedrooms
  • 4 Bathrooms
  • Sleeps 10
New! Private Home Downtown at Emerson Sq...

Summary:Brand new Home in the heart of downtown Charleston. This Professionally designed private residence offers a warm and inviting aesthetic, with a huge 3rd floor primary suite featuring a bespoke constructed king size bed and a roomy private...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 6
Carolina Rose | Southern Luxurious Escap...

Permit Number: 06352The Space: Escape to The Carolina Rose on Cannon for an unparalleled blend of luxury and comfort! ????✨ This newly constructed gem welcomes groups of up to 8 guests, offering four lavish King Beds, each with private full...

  • Charleston
  • 4 Bedrooms
  • 4 Bathrooms
  • Sleeps 8
Harleston House | Unit A | Sleeps 10

Summary:Welcome to the Harleston House in the Preserve, a chic 4-bedroom, 4-bathroom luxury suite in downtown Charleston. This modern getaway, complete with modern furnishings and a private plunge pool, offers an exclusive escape for guests seeking...

  • Charleston
  • 4 Bedrooms
  • 4 Bathrooms
  • Sleeps 10
Charleston Charm - 3 Bedroom - 2 Blocks ...

Feel the timeless appeal of Charleston’s historic peninsula, the Holy City. Stay just mins. from MUSC, the College of Charleston, and the vibrant shopping, dining, and nightlife of King Street. From this ideally located downtown home, you’ll be...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 8
1 Block to King St | Plunge Pool | Sleep...

Summary:Feel luxury at The Pink Palm, a striking new construction 4-bedroom, 4-bathroom getaway in downtown Charleston finished in APR 2025. Savor cavernous living areas, fashonable baths, and a entirely equipped kitchen. Unwind in the private...

  • Charleston
  • 4 Bedrooms
  • 4 Bathrooms
  • Sleeps 10