Charleston-SC.com logo

Charleston, SC 2+ Bedroom Vacation Rentals

Filter 2+ Bedroom Charleston Properties by: Company | Oceanfront | Pet-Friendly | or choose different a Area or Bedrooms
No company options available.
Bedrooms:
1052 rentals found
Extended Stay in Charleston! 5 Mi to His...

Near Business & Medical Centers | Painless Highway Access | Fenced Yard Headed to Charleston for a long-term visit? This vacation rental is ideal for making the most of your time in the Lowcountry! The 3-bed, 2-bath home has all the essentials...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 6
Where Tranquility Blooms | Blossoms on C...

Permit Number: 06351The Space: Welcome to Blossoms on Cannon, a attractively restored two story Charleston home designed for comfort, connection, and memorable group stays in the heart of downtown!Bedrooms & Bathrooms• Five bedrooms thoughtfully...

  • Charleston
  • 5 Bedrooms
  • 4 Bathrooms
  • Sleeps 11
Guesthouse Charleston: WEST (62 & 64)

West 62 and 64 are two striking homes located next door to each other, sharing a cavernous outdoor courtyard ideal for calming with drinks after a day of exploring Charleston. Each home offers generous living spaces, enormous bedrooms, and multiple...

  • Charleston
  • 8 Bedrooms
  • 9 Bathrooms
  • Sleeps 20
The Rutledge Roost of Charleston

This 2-bedroom bungalow is ideal for your escape to Charleston. With 2 appealing king beds, a comfortable living space, and a entirely equipped bathroom with a shower, this adorable getaway has everything you need for an impressive stay. Whether...

  • Charleston
  • 2 Bedrooms
  • 1 Bathrooms
  • Sleeps 4
Downtown Charleston Home + Private Pool

Summary:Ideal for a enormous family! This listing is for the entire home. The home sleeps 16 guests total. Your stay just got an upgrade. 118B President Street now features a freshly finished private plunge pool, sun deck with loungers, and outdoor...

  • Charleston
  • 6 Bedrooms
  • 6 Bathrooms
  • Sleeps 16
The Crab House: Built 2022. Huge propert...

Summary:King Bed, Walk-In Shower, Game room w/ 120' Projector, 9 outdoor swings... names a few of our loaded amenities.-2615 Sq Ft Home…-Minutes from Downtown Charleston.-Extensive parking, Gym, Intelligent Home Integration, Grille, Fire...

  • Charleston
  • 4 Bedrooms
  • 3 Bathrooms
  • Sleeps 10
Charleston Loft | Exclusive Party-Friend...

Step inside Hank’s Loft, a gorgeous Charleston getaway where historic appeal meets modern luxury. With three king bedrooms, en-suite baths, and a private billiard room, every detail invites relaxation. The chef’s kitchen with Viking appliances...

  • Charleston
  • 3 Bedrooms
  • 3 Bathrooms
  • Sleeps 6
Landing | Spectacular 2BD, Yoga Studio, ...

Luxury meets laid-back coastal stays at Avalon at James Island in Charleston. Our furnished apartments feature full kitchens, quartz countertops, cavernous walk-in closets, and wrap-around balconies with soaring 9-foot ceilings. Appreciate premium...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 4
The Bogard House 2BD + Free Parking

Feel the unique beauty of Charleston in this freshly-refreshed two bedroom historic home in the trendy, laid-back Cannonborough neighborhood. Whether you’re appreciating scrumptious meals at close by eateries, delighting in the historic sights and...

  • Charleston
  • 2 Bedrooms
  • 1 Bathrooms
  • Sleeps 4
Beautiful Cottage-Style Home Minutes Fro...

Welcome to Charlie’s Charming Cottage! This handsome bungalow-style home is tucked away in a relaxing, centrally located neighborhood and has all the appeal, comfort, and amenities to make it your home away from home. Only 10 mins. to downtown...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 4
Blue Magnolia | Perfect for Large Groups

Summary:Discover Blue Magnolia, your modren and cavernous Charleston getaway. This 7BR/4BA home combines classic Southern appeal with modern comfort, making it ideal for families or groups. Unwind on the inviting front porch, soak in the airy...

  • Charleston
  • 7 Bedrooms
  • 4 Bathrooms
  • Sleeps 17
The Queens Palace | 8 Bedrooms in Charle...

Permit Number: 05553The Space: Welcome to The Queen’s Palace, your private Charleston getaway made up of three attractively restored historic homes in the heart of the Cannonborough–Elliotborough neighborhood. With eight bedrooms, eight...

  • Charleston
  • 8 Bedrooms
  • 8 Bathrooms
  • Sleeps 16
Quiet Retreat in Downtown Charleston –...

The Coach House – Historic Charm & Cozy Living in Downtown CharlestonTucked behind the Wickliffe House in the heart of Charleston's medical district, The Coach House is a 3-bedroom, 3-bath home offering timeless character and refreshed comfort in...

  • Charleston
  • 3 Bedrooms
  • 3 Bathrooms
  • Sleeps 6
Spectacular Riverview Home Near Folly Be...

Located close to Folly Beach and Downtown, this spectacular single-family guest home sits on an broad, private lot with serene vistas of the Muni golf course and Stono River. Adorned with many of the Lowcountry's famed majestic Grandiose Oaks, this...

  • Charleston
  • 2 Bedrooms
  • 1 Bathrooms
  • Sleeps 8
Historic Charleston Right Outside Your F...

One of four residences in this 1870s-era historic remodeled property, the 1,500-square-foot "Jasper Suite" residence offers you a comfortable getaway. Blending the best of old and new, this historic home has been completely refurbished with modern...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 4
Rantum Scoot of Downtown Charleston

Offered for the first time on Vacation Rental By Owner! This freshly refreshed entirely furnished 3-bedroom, 2-bathroom gem offers a comfortable and convenient living experience. Located in a peaceful neighborhood just two blocks off the bustling...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 6
The Jessamine | Verdana | Historic Downt...

Summary:Welcome to The Jessamine, a downtown Charleston treasure where historic elegance meets modern comfort just steps from King Street. This appealing home features original wide-plank pine floors, a private garden courtyard ideal for morning...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 7
Grand 18bd House w. Luxury Finishes + Pa...

Summary:As part of the esteemed collection, The Heirloom, this impressive 18-bedroom compound is located on Spring Street in the heart of Charleston. Ideal for sizable groups, this completely remodeled property combines two handsome Victorian homes...

  • Charleston
  • 18 Bedrooms
  • 14 Bathrooms
  • Sleeps 30