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Charleston, SC 4+ Bedroom Vacation Rentals

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358 rentals found
Quality Design - Downtown - Steps to Kin...

Summary:Welcome to your Charleston stay in Quality Design, a refined home where artistic touches, thoughtful materials, and walkability combine for a stay that feels both extravagant and local. Ideal for design lovers, couples or group travelers who...

  • Charleston
  • 4 Bedrooms
  • 4 Bathrooms
  • Sleeps 10
The Chapel | Manor 4BR Charming Charlest...

Summary:Welcome to your Charleston getaway located just moments from King Street, where classic appeal meets modern comfort. This 4-bedroom, 4-bath home is ideal for families or groups who want privacy, ease, and access to Charleston’s best...

  • Charleston
  • 4 Bedrooms
  • 4 Bathrooms
  • Sleeps 10
Southern Ease, Contemporary Flair | The ...

Permit Number: 06855The Space: Welcome to The Charleston, where timeless Southern appeal meets modern comfort in a gorgeously restored 1852 historic home offering exclusive access to the entire second and third floors in the heart of downtown!With 4...

  • Charleston
  • 4 Bedrooms
  • 3 Bathrooms
  • Sleeps 8
The Saint | Newly Built Charleston Home ...

Summary:Welcome to The Saint, a freshly constructed Charleston home that showcases striking architectural design and modern comfort in a walkable urban setting. Ideal for families, friends, or style-conscious travelers who savor light-filled spaces...

  • Charleston
  • 4 Bedrooms
  • 3 Bathrooms
  • Sleeps 12
Cannon Collective | 5BR Historic Home Do...

Summary:Welcome to Cannon Collective, a cavernous 5 bedroom home in downtown Charleston full of character, elegance and prime access. Ideal for sizable groups, families or gatherings looking for comfort, appeal and space. You will find yourself...

  • Charleston
  • 5 Bedrooms
  • 4 Bathrooms
  • Sleeps 15
Perfect family home in West Ashley, minu...

PROMO 5% WEEKLY DISCOUNT!Welcome to your home away from home while in Charleston. Our 2000 square foot home is located in a peaceful neighborhood, encompassed in the beauty of Low Country Marshes in West Ashley. We have lovingly refreshed the home...

  • Charleston
  • 4 Bedrooms
  • 2 Bathrooms
  • Sleeps 8
New design & construction, 6 Bed, 6 EnSu...

Welcome to 183 Saint Philip Street, your chic haven in the heart of Charleston! This new construction offers a prime location, placing you steps away from the city's vibrant attractions & best eateries. Each bedroom features 55" Samsung TVs ...

  • Charleston
  • 6 Bedrooms
  • 6 Bathrooms
  • Sleeps 16
The OakTree | Stylish Bohemian Downtown ...

Summary:Welcome to The OakTree, your boho-chic haven in the heart of downtown Charleston, where artistic flair meets generous space. Ideal for enormous groups, families, or creative retreats, this 7-bedroom home offers character, comfort, and close...

  • Charleston
  • 7 Bedrooms
  • 7 Bathrooms
  • Sleeps 16
Near Citadel Mall! Extended Getaway 8 Mi...

1/2 Mi to Movie Theater & Dining | Suburban Neighborhood | 15 Mi to Folly BeachSwap the snow for the South Carolina sunshine! This Charleston vacation rental offers the ideal base for snowbirds and those seeking long-term accommodations. Kick off...

  • Charleston
  • 4 Bedrooms
  • 2 Bathrooms
  • Sleeps 8
4 Bedroom - 4 Blocks to King St. with Pa...

Feel the timeless appeal of Charleston’s historic peninsula, the Holy City. Stay just mins. from MUSC, the College of Charleston, and the vibrant shopping, dining, and nightlife of King Street. From this ideally located downtown home, you’ll be...

  • Charleston
  • 4 Bedrooms
  • 2 Bathrooms
  • Sleeps 10
EAST 46 G & H - 2 Units, Connected Inter...

Two handsome adjoining apartments offering a total of 5 bedrooms, 5 bathrooms, 2 full kitchens, and 2 roomy living rooms, making them ideal for bigger groups or families seeking both space and comfort. Located just one block from King Street in...

  • Charleston
  • 5 Bedrooms
  • 5 Bathrooms
  • Sleeps 14
Brand New, Chic 5 Bed Rental with Porch,...

Summary:Feel modern luxury in historic Charleston at The Hawthorne! This brand-new 4-bed, 4-bath home is steps from King Street's vibrant energy. Ideal for groups, it features a full kitchen, private balcony, and sizable comfortable living room for...

  • Charleston
  • 4 Bedrooms
  • 4 Bathrooms
  • Sleeps 10
Relaxing, boho home, central to many att...

We are new to Vacation Rental By Owner but well established on @irbnb with super host status and many reviews.Kick back and relax in this calm, modren home just mins. from some of Charleston's most trendy attractions. This home is a ideal central...

  • Charleston
  • 4 Bedrooms
  • 2 Bathrooms
  • Sleeps 10
8 Bedroom - Close to King Street - with ...

Feel the timeless appeal of Charleston’s historic peninsula, the Holy City. Stay just mins. from MUSC, the College of Charleston, and the vibrant shopping, dining, and nightlife of King Street. From this ideally located downtown home, you’ll be...

  • Charleston
  • 8 Bedrooms
  • 4 Bathrooms
  • Sleeps 16
Luxurious 4 Bedroom, 4.5 Bath Home

Located in the vibrant heart of Charleston`s historic Cannonborough-Elliottborough neighborhood, this roomy and chic home invites you to experience the appeal and hospitality of the South like never before. Whether you`re here to discover the rich...

  • Charleston
  • 4 Bedrooms
  • 4 Bathrooms
  • Sleeps 10
Game Room• Fireplace • Backyard Deck...

Welcome to Your Storybook Hideaway * 16 miles to Historic Downtown Charleston* 25 miles to Folly Beach and Isle of Palm* 6.4 miles to Charleston International Airport* Free Wi-Fi and self-check-in* Free parking available* Fireplace* Entirely...

  • Charleston
  • 4 Bedrooms
  • 2 Bathrooms
  • Sleeps 10
The Chapel | Verdana 4BR DT Charleston -...

Summary:Welcome to The Chapel, your downtown Charleston getaway combining historic appeal, modern amenities, and unbeatable walkability. Ideal for families, groups of friends, or modest gatherings, this 4-bedroom home offers style, comfort, and a...

  • Charleston
  • 4 Bedrooms
  • 4 Bathrooms
  • Sleeps 10
The Helène House - Spacious 4BD, 4.5BA ...

Summary:Freshly remodeled 4BR/4.5BA home in laid-back Cannonborough/Elliotborough, ideal for families or friends. Lady Helene, Unit B features 4 ensuite bedrooms, open living/dining, a completely equipped kitchen, games room, private porch...

  • Charleston
  • 4 Bedrooms
  • 4 Bathrooms
  • Sleeps 8