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Charleston, SC 4+ Bedroom Vacation Rentals

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356 rentals found
Downtown near King St - 4BR/2BA

Summary:Step inside this bright 4 bedroom, 2 bathroom home located just steps from the energy and appeal of King Street. Ideal for families, groups of friends, or extended stays, you’ll appreciate the balance of roomy interiors, classic touches...

  • Charleston
  • 4 Bedrooms
  • 2 Bathrooms
  • Sleeps 10
Pet Friendly Spacious 4BR Family Home Ne...

Kick back and relax in this calm, fresh home just mins. from some of Charleston's most trendy attractions. This home is a ideal central location as you discover all Charleston has to offer. The home is located on a peaceful street with plenty of...

  • Charleston
  • 4 Bedrooms
  • 2 Bathrooms
  • Sleeps 10
True Southern Historic Charm by the Batt...

Step into Charleston’s history with this impressive 4-bedroom, 4-bathroom circa-1830 home, just steps from Rainbow Row and The Battery. This opulent getaway offers period antiques, crystal chandeliers, and huge piazzas, blending historic appeal...

  • Charleston
  • 4 Bedrooms
  • 4 Bathrooms
  • Sleeps 9
Belle Haven Duplex - Downtown - New Reno...

Feel the timeless appeal of Charleston’s historic peninsula, the Holy City. Stay just mins. from MUSC, the College of Charleston, and the vibrant shopping, dining, and nightlife of King Street. From this ideally located downtown home, you’ll be...

  • Charleston
  • 4 Bedrooms
  • 2 Bathrooms
  • Sleeps 8
Game Room• Fireplace • Backyard Deck...

Bring your family and friends to Your Storybook Hideaway for fun in the humongous game room, relax in the enormous open living area, or appreciate a lowcountry dinner on the back deck. Full of majestic sizable oaks, the neighborhood is peaceful ...

  • Charleston
  • 4 Bedrooms
  • 2 Bathrooms
  • Sleeps 10
Cozy 4bd Home with Porch, Near King Stre...

Summary:Welcome to your cavernous Charleston getaway, where modern remodel meets classic appeal. This rare 4-bedroom home is made up of two entirely equipped units rented together, offering the ideal setup for families or groups who want both...

  • Charleston
  • 4 Bedrooms
  • 2 Bathrooms
  • Sleeps 10
4 Bedroom - 2 Blocks to King Street with...

Feel the timeless appeal of Charleston’s historic peninsula, the Holy City. Stay just mins. from MUSC, the College of Charleston, and the vibrant shopping, dining, and nightlife of King Street. From this ideally located downtown home, you’ll be...

  • Charleston
  • 4 Bedrooms
  • 3 Bathrooms
  • Sleeps 8
New Build - Steps to King Street

Feel the epitome of modern Charleston living in this gorgeous, brand new, 5-bedroom, 5-bathroom vacation rental apartment, aptly named The Chateau. Located in the heart of downtown Charleston, this extravagant abode offers an unbeatable location...

  • Charleston
  • 5 Bedrooms
  • 5 Bathrooms
  • Sleeps 14
Grand 10BR Charleston Home with Speakeas...

Summary:Draped in Spanish moss and located within a beautiful Charleston neighborhood, Heirloom on Cannon is a sizable 10-bedroom, 7-bath getaway blends timeless Southern character with modern luxury. Recently modernized in September 2025, this...

  • Charleston
  • 10 Bedrooms
  • 7 Bathrooms
  • Sleeps 26
Luxe 7bd, 6ba Retreat, Steps from King

Summary:Stay steps from upper King Street in this refined getaway blending luxury and appeal. Featuring sleek interiors, modern amenities, and vistas of Charleston’s vibrant downtown, it’s ideal for travelers who want shopping, dining, and...

  • Charleston
  • 7 Bedrooms
  • 6 Bathrooms
  • Sleeps 16
The Isla Suite: A Dream Getaway for Frie...

The Isla Suite: A Dream Getaway for FriendsThe Isla Suite is a vibrant first-floor getaway in impressive Charleston, crafted for an memorable friends’ group hideaway. Positioned just steps from downtown’s premier drink bars, top-rated eateries...

  • Charleston
  • 4 Bedrooms
  • 2 Bathrooms
  • Sleeps 8
11 Bed Compound for Large Groups, Prime ...

Summary:Welcome to The Grandiose Estate, a private getaway in the heart of downtown Charleston, SC. Located within a meticulously restored historic home, this exclusive property features four completely furnished residences, creating the ideal...

  • Charleston
  • 11 Bedrooms
  • 8 Bathrooms
  • Sleeps 24
Autumn Getaway: Sleeps 16+BackPatio | Ne...

Sleeps up to 16! This modern, freshly modernized home consists of 2 huge apartments, rentable separately or together. You have a private backyard to relax/dine with a wide umbrella. Wood floors sit beneath exposed beams, w/ stainless steel...

  • Charleston
  • 6 Bedrooms
  • 4 Bathrooms
  • Sleeps 16
The Jessamine | 9BR Historic Downtown Ab...

Summary:Welcome to your Cannonborough hideaway, a newly refreshed 3-unit property just one block from iconic King Street. Ideal for families or groups of friends, this getaway blends comfort, style, and convenience. With updated interiors, a calming...

  • Charleston
  • 9 Bedrooms
  • 5 Bathrooms
  • Sleeps 16
Casa Fuego - Suites D and E

Permit Number: 05792The Space: Welcome to Casa Fuego — Suites D & E, a cavernous dual-suite getaway designed for bigger groups who want both connection and privacy. With two private apartments in one property, this setup offers 4 bedrooms, 2...

  • Charleston
  • 4 Bedrooms
  • 2 Bathrooms
  • Sleeps 10
Downtown Historic Home Close to Neighbor...

Summary:Welcome to this vibrant downtown getaway! Originally constructed in 1905 and freshly refreshed, this colorful home blends historic appeal with modern comfort. With eight uniquely styled bedrooms and eight handsomely updated bathrooms...

  • Charleston
  • 8 Bedrooms
  • 4 Bathrooms
  • Sleeps 16
The Marquee On King & Historic Market!

Permit Number: 51196The Space: Welcome to The Marquee, a roomy two-level condo combination located directly on historic King Street and ideal for sizable groups exploring downtown Charleston!With two connected condos spanning the second and third...

  • Charleston
  • 6 Bedrooms
  • 4 Bathrooms
  • Sleeps 13
Only 2 Blocks to King | The Gemstone (Su...

Permit Number: 06819The Space: Welcome to this handsomely designed 4-bedroom, 4-bath downtown Charleston home, thoughtfully curated for comfort, style, and an exceptional stay just two blocks from King Street!This inviting getaway offers open...

  • Charleston
  • 4 Bedrooms
  • 4 Bathrooms
  • Sleeps 9