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Charleston, SC 4+ Bedroom Vacation Rentals

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362 rentals found
Brand NEW! 5BR/5BA Home, Perfect for Gro...

26 Bee Street features two distinct units in Charleston's charming Cannonborough/Elliotborough neighborhood. This vibrant property includes five bedrooms and five bathrooms across both units, each attractively restored to showcase historic appeal...

  • Charleston
  • 5 Bedrooms
  • 5 Bathrooms
  • Sleeps 10
The Lord Ashley - Sleeps 8!

Our sun-filled home features an inviting open floor plan that includes two sitting rooms and a enormous dining area with bar that leads into the cavernous chef's kitchen. The completely equipped kitchen is complete with stainless steel appliances...

  • Charleston
  • 4 Bedrooms
  • 2 Bathrooms
  • Sleeps 8
Screened Porch + Grill: Spacious Charles...

3,000 Sq Ft | Family-Friendly Conveniences | 3 Mi to Folly BeachMake this 5-bedroom, 3-bathroom vacation rental your home base as you discover all Charleston has to offer. The 'James Island Folly Family Retreat' includes multiple living areas, ideal...

  • Charleston
  • 5 Bedrooms
  • 3 Bathrooms
  • Sleeps 10
Vacation Villa 5 mins to King 'Travelers...

Summary:Vacation Villa 5 min. walk to King St, in the heart of downtown Charleston. This tropical getaway offers sleek design, soaring 25’ ceilings, open first floor kitchen & living room, and roomy bedrooms with en-suite spa bathrooms. The Palm...

  • Charleston
  • 5 Bedrooms
  • 5 Bathrooms
  • Sleeps 14
The Historic St. Philip House - One Bloc...

**Daniel and I wanted to inform you of a new construction project that has newly started on the lot adjacent to our home. The construction will be active Monday-Friday and possibly on Saturday's. The starting time during the week is possibly as...

  • Charleston
  • 4 Bedrooms
  • 3 Bathrooms
  • Sleeps 8
Harleston House | Unit A | Sleeps 8

Summary:Welcome to the Harleston House in the Preserve, a classy 4-bedroom, 4-bathroom luxury suite in downtown Charleston. This modern getaway, complete with modern furnishings and a private plunge pool, offers an exclusive escape for guests...

  • Charleston
  • 4 Bedrooms
  • 4 Bathrooms
  • Sleeps 8
The Mary Scott and Daniel Legare House

Permit Number: 06948The Space: Welcome to your Charleston getaway at 11 George Street!This striking and cavernous home features 5 elegantly appointed bedrooms and 3 full bathrooms, making it an ideal getaway for families, friends, or bigger groups...

  • Charleston
  • 5 Bedrooms
  • 3 Bathrooms
  • Sleeps 16
Charming 4-bedroom house with AC and WiF...

Stay comfortably in Charleston at this 4-bedroom home. Each bedroom features 1 king bed and 3 queen beds, ideal for a group hideaway. Appreciate the serene and calming ambiance of this cozy property, complete with 3 bathrooms equipped with showers...

  • Charleston
  • 4 Bedrooms
  • 2 Bathrooms
  • Sleeps 8
Charleston Riviera | King Street Home - ...

Summary:Welcome to Charleston Riviera, a elegantly appointed home that blends style, comfort, and prime walkability. Located just steps from King Street, this getaway is ideal for couples or modest groups who want modren amenities, chic touches, and...

  • Charleston
  • 4 Bedrooms
  • 2 Bathrooms
  • Sleeps 9
Belle Haven Duplex - Downtown - New Reno...

Feel the timeless appeal of Charleston’s historic peninsula, the Holy City. Stay just mins. from MUSC, the College of Charleston, and the vibrant shopping, dining, and nightlife of King Street. From this ideally located downtown home, you’ll be...

  • Charleston
  • 4 Bedrooms
  • 2 Bathrooms
  • Sleeps 8
Stunning 6-Bedroom Home with Pool, 5.5 B...

More photos coming soon!Dive in to this freshly modernized 6-bedroom, 5.5 bathroom home with a brand new pool, ideal for hosting up to 12 guests. This three-story haven, adorned with wood floor, original fireplaces, and high ceilings with exposed...

  • Charleston
  • 6 Bedrooms
  • 5 Bathrooms
  • Sleeps 12
Spacious & Modern 4bd, 2 blocks to King!

Summary:Welcome to your beautiful Charleston getaway just two blocks from lively King Street. This cavernous 4-bedroom, 5-bath home blends comfort and style. Step outside and walk to the city’s best eateries, stores, and nightlife, then return to...

  • Charleston
  • 4 Bedrooms
  • 5 Bathrooms
  • Sleeps 9
The President St Trio - 8 Bedroom

Summary:Group-friendly, three-home complex, centrally located in Downtown Charleston! - Over 5,000 square feet- Great for enormous groups—spend time together, but everybody can have their space!- Open-air porches, welcoming living areas ...

  • Charleston
  • 8 Bedrooms
  • 6 Bathrooms
  • Sleeps 16
Luxe Downtown 4 Bed w/ Porch + Parking &...

Summary:Feel The Charlee on Cannon, a brand-new 4BR, 3BA private unit offering refined style and modern convenience in downtown Charleston. Appreciate a cavernous open-concept living area, private balcony, intelligent TVs in every room, and...

  • Charleston
  • 4 Bedrooms
  • 3 Bathrooms
  • Sleeps 10
Downtown Charleston - 4BR Luxurious Geta...

Summary:Discover this 4BR/4BA Charleston hideaway, ideally located just off King Street in the Crosstown neighborhood. Each bedroom offers a private en suite, with modern design, Intelligent TVs, and high-speed WiFi throughout. Savor a completely...

  • Charleston
  • 4 Bedrooms
  • 4 Bathrooms
  • Sleeps 9
Spend The Weekend Aboard Your Own Privat...

Under new ownership as of May 2017. Located in the Heart of Charleston's Historic District, Southern Comfort is docked at the Charleston City Marina and less than 50 feet from our gated parking lot.We are 3 blocks from the Historic Battery just...

  • Charleston
  • 4 Bedrooms
  • 4 Bathrooms
  • Sleeps 8
Guesthouse Charleston: WEST (62)

At 62 West, you'll feel right at home during your Charleston visit—front porch supplied! In addition to comfortable beds, this home offers a roomy open-concept living room and kitchen, ideal for entertaining. The gorgeously landscaped outdoor...

  • Charleston
  • 4 Bedrooms
  • 4 Bathrooms
  • Sleeps 10
Regal 7bd Luxury Design w. Speakeasy Bar...

Summary:Surrounded by swaying Spanish moss in one of Charleston’s most striking neighborhoods, Heirloom on Cannon is a impressive 7-bedroom, 5-bath home captures the essence of Southern grace with modern amenities. Thoughtfully modernized in...

  • Charleston
  • 7 Bedrooms
  • 5 Bathrooms
  • Sleeps 14