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Charleston, SC 4+ Bedroom Vacation Rentals

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342 rentals found
Poolside Paradise Getaway - North Charle...

Summary:Feel a calming and modren getaway in our gorgeously appointed five-bedroom, three-bathroom single-family home in North Charleston. Designed with discerning guests in mind, this property offers modern amenities and refined amenities, making...

  • Charleston
  • 5 Bedrooms
  • 3 Bathrooms
  • Sleeps 12
The Palmetto | Rooftop Deck, Perfect for...

Summary:Feel Charleston living in this freshly refreshed 4BR/4.5BA getaway, ideal for friends or families. Located in the laid-back Cannonborough neighborhood, you’ll be steps from vibrant dining, rich history, and local appeal. Just 3 blocks from...

  • Charleston
  • 4 Bedrooms
  • 4 Bathrooms
  • Sleeps 10
Historic Charleston Home | STEPS from Ki...

Summary:Welcome to this appealing historic Charleston home, where timeless craftsmanship and modern amenities come together in an unbeatable location. Ideal for families or friends who adore character and convenience, this property offers you...

  • Charleston
  • 4 Bedrooms
  • 2 Bathrooms
  • Sleeps 12
Downtown Charleston Gem | Walk Everywher...

Summary:Welcome to The Lavender???? & Sage Suites ???? a handsomely restored 6BR 6.5BA home that pairs modern luxury with timeless Southern appeal. Located in the heart of downtown Charleston, you're just steps from the city's best eateries...

  • Charleston
  • 6 Bedrooms
  • 6 Bathrooms
  • Sleeps 12
The Cocktail Soiree | 4 Bedrooms | King ...

Permit Number: 05769,05770,05771,05772The Space: Welcome to your ultimate King Street hideaway! ????✨This one-of-a-kind property features four private apartments spread across two floors — each with its own entrance, queen-sized bed, private...

  • Charleston
  • 4 Bedrooms
  • 4 Bathrooms
  • Sleeps 8
The Grand Oak - Walk to King!

Brand new 4-bedroom, 4.5-bathroom home in historic Charleston with classic double porches and on-site parking. Located just a short walk from Upper King Street in the Cannonborough-Elliotborough neighborhood, The Grandiose Oak offers the ideal...

  • Charleston
  • 4 Bedrooms
  • 4 Bathrooms
  • Sleeps 10
Vacation Villa 5 mins to King ‘The Roy...

Summary:Vacation Villa 5 min. walk to King St, in the heart of downtown Charleston. This tropical getaway offers sleek design, soaring 25’ ceilings, open first floor kitchen & living room, and cavernous bedrooms with en-suite spa bathrooms. The...

  • Charleston
  • 5 Bedrooms
  • 5 Bathrooms
  • Sleeps 14
The Soiree by Charleston Vacays-New Buil...

Feel the epitome of modern Charleston living in this gorgeous 5-bedroom, 5-bathroom vacation rental, aptly named The Soiree. Located in the heart of downtown Charleston, this opulent abode offers an unbeatable location. Upper King Street, just a...

  • Charleston
  • 5 Bedrooms
  • 5 Bathrooms
  • Sleeps 14
The Bogard Duo 6 Bed 6 Bath

Freshly-refreshed six bedroom historic home in the fashionable, laid-back Cannonborough neighborhood close to great eateries & historical sights.This classic Charleston home is made up of two units A&B, this is the listing for both units. The entire...

  • Charleston
  • 6 Bedrooms
  • 6 Bathrooms
  • Sleeps 12
The Mary Scott and Daniel Legare House

Permit Number: 05793The Space: Welcome to your Charleston getaway at 11 George Street! This appealing and cavernous home features 6 elegantly appointed bedrooms and 3 bathrooms, ideal for accommodating sizable groups or families.The sleeping...

  • Charleston
  • 5 Bedrooms
  • 3 Bathrooms
  • Sleeps 16
New! The Palmetto House- 3 Blocks To Kin...

Summary:Feel the ideal fusion of history and modern luxury at The Palmetto House, This remarkable 4-bedroom, 3-bath second-floor apartment is located within a historic Charleston home. This gorgeous getaway is your gateway to Charleston, located...

  • Charleston
  • 4 Bedrooms
  • 3 Bathrooms
  • Sleeps 8
Spring St - Downtown Charleston - Walk E...

Feel the timeless appeal of Charleston’s historic peninsula, the Holy City. Stay just mins. from MUSC, the College of Charleston, and the vibrant shopping, dining, and nightlife of King Street. From this ideally located downtown home, you’ll be...

  • Charleston
  • 4 Bedrooms
  • 4 Bathrooms
  • Sleeps 10
5 bdr +6 baths | 5 Mins walk 2 King St| ...

Summary:Welcome to your comfortable Charleston getaway! This inviting 5-bedroom home is just 5 mins. from vibrant King Street and surrounded by the rich appeal and history of the city. Thoughtfully decorated with warm, rustic touches, it’s the...

  • Charleston
  • 5 Bedrooms
  • 6 Bathrooms
  • Sleeps 13
The Inns 5 Bed 3 Bath Luxury Home 2 Bloc...

Summary:This modren 5-bedroom, 3-bath luxury home is ideally located just two blocks from King Street. Freshly remodeled and professionally furnished, it offers cavernous living areas, high-end finishes, and thoughtful touches throughout. Ideal for...

  • Charleston
  • 5 Bedrooms
  • 3 Bathrooms
  • Sleeps 14
The Rose Charleston | Perfect for Large ...

Summary:Escape to The Rose, a elegantly refreshed 2-story Charleston classic in the heart of downtown. With 6 bedrooms and 4 bathrooms, this classy getaway is ideal for sizable groups seeking both space and comfort. Unwind in the inviting living...

  • Charleston
  • 6 Bedrooms
  • 4 Bathrooms
  • Sleeps 16
The Marquee On King & and  Historic Mark...

Permit Number: 51196The Space: Property Overview: The Marquee - Features 6 bedrooms and 4 full bathrooms, offering ample space and privacy for huge groups. -Roomy 2nd and 3rd-floor condo combination, ideal for groups of up to 13 guests. ...

  • Charleston
  • 6 Bedrooms
  • 4 Bathrooms
  • Sleeps 13
Casa Zoë | Grand Federal Sparrow House ...

Summary:OP2025-05862Sparrow House is a stately Federal-style, National Register residence reimagined for modern group stays. This full-home Casa Zoë gem blends historic appeal—porches, millwork, heart pine floors—with bold, gallery-worthy...

  • Charleston
  • 4 Bedrooms
  • 3 Bathrooms
  • Sleeps 13
Casa Zoë | Royal House – Charlestonâ€...

Summary:OP2025-06816OP2025-06817The Royal House is Charleston’s ultimate group escape: a dual-unit Casa Zoë mansion that blends grandeur, design, and independence. With 8 bedrooms, 8 baths, and separate living quarters, it offers shared elegance...

  • Charleston
  • 8 Bedrooms
  • 10 Bathrooms
  • Sleeps 16