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Charleston, SC 4+ Bedroom Vacation Rentals

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343 rentals found
The King | Luxury Home w/ Rooftop Patio

Summary:Discover luxury in this completely refreshed haven, located just moments from King St. Indulge in classy interiors awash with natural light from wrap-around windows. This Charleston treasure features 4 bedrooms and 3.5 bathrooms with rain...

  • Charleston
  • 4 Bedrooms
  • 3 Bathrooms
  • Sleeps 10
Revitalized Historical Southern Residenc...

Summary:Ideal for a sizable family! Just one block away from upper King Street, the new epicenter of the city's acclaimed restaurant and nightlife district. Savor some of Charleston's best local dining, all located within just a few blocks of the...

  • Charleston
  • 4 Bedrooms
  • 3 Bathrooms
  • Sleeps 10
Magnolia House | Historic Charleston Hom...

Summary:Welcome to Magnolia House, a grandiose 6 bedroom, 3 bathroom two-story Charleston style home that blends timeless character with comfortable, modern touches. Ideal for families or groups seeking space, beauty, and convenience in one place...

  • Charleston
  • 6 Bedrooms
  • 3 Bathrooms
  • Sleeps 19
3 Luxury Houses w/ Patios | 1 Block from...

Summary:Discover luxury set of three completely modernized luxury homes ideal for a sizable group, located next door to each other just moments from King St. Indulge in chic interiors awash with natural light from wrap-around windows. These...

  • Charleston
  • 12 Bedrooms
  • 10 Bathrooms
  • Sleeps 30
The Grand Oak - Walk to King!

Brand new 4-bedroom, 4.5-bathroom home in historic Charleston with classic double porches and on-site parking. Located just a short walk from Upper King Street in the Cannonborough-Elliotborough neighborhood, The Grandiose Oak offers the ideal...

  • Charleston
  • 4 Bedrooms
  • 4 Bathrooms
  • Sleeps 10
Wilhelmenia Suites • 4BR Near King •...

Summary:Welcome to The Wilhelmenia Suites, a classy and cavernous rental just two blocks from King Street in the heart of Charleston. This second floor property features two connected suites with a total of four bedrooms and two bathrooms, ideal for...

  • Charleston
  • 4 Bedrooms
  • 2 Bathrooms
  • Sleeps 12
Lovely 4BR/2BA Home! Less Than 10 Minute...

Our handsome 4 bedroom/2 bath home is located on a peaceful street with little traffic. Drive 10 mins. to Downtown Charleston and 8 mins. to Folly Beach. Appreciate plenty of space, as well as great beds (1 king, 2 queens, 1 full) and a outfitted...

  • Charleston
  • 4 Bedrooms
  • 2 Bathrooms
  • Sleeps 7
Group Getaway - 6BR/6BA in Heart of Char...

Summary:Traveling with a group? This property is ideal - all six bedrooms have full ensuite baths. Note that this listing is a combination of two individual five star units within the same building with dozens of reviews.The Space:This...

  • Charleston
  • 6 Bedrooms
  • 6 Bathrooms
  • Sleeps 12
Casa Zoë | Cabana House – Bold Design...

Summary:OP2025-05859Casa Zoë’s Cabana House is bright, beautiful, and chic. With well-appointed bedrooms, designer touches throughout, and 3 porches ideal for gathering, it’s ideal for bachelorette weekends or getaways with friends. Appreciate...

  • Charleston
  • 4 Bedrooms
  • 4 Bathrooms
  • Sleeps 11
Renovated two-story home in Charleston w...

Summary:21 Hampden Ct - 30 Day RentalThe Space:Make yourself at home at this traditional, early 1800s two-story home near the heart of Charleston! It's been refreshed and thoughtfully decorated to provide guests with the best lodging experience...

  • Charleston
  • 4 Bedrooms
  • 3 Bathrooms
  • Sleeps 8
4 BR with Rooftop - Cozy Home near King ...

Welcome to the Holy City, and the historic southern appeal of the Charleston peninsula. Our Vacation Rental By Owner is located in striking downtown Charleston and just mins. away from MUSC, the College of Charleston, and King Street’s shopping...

  • Charleston
  • 4 Bedrooms
  • 5 Bathrooms
  • Sleeps 12
Porches, Patio & Parking – 2 Blocks to...

Summary:✨ Welcome to Azaleas on Spring! ???????? 2 Blocks to King St! Walk to Charleston’s Finest Dining, Shopping & Nightlife???? Ideal for Substantial Groups – Families, Wedding Guests, Bachelor(ettes) & Work Retreats???? Multiple Outdoor...

  • Charleston
  • 7 Bedrooms
  • 7 Bathrooms
  • Sleeps 18
Guesthouse Charleston: WEST (242 B)

West 242 B is a striking standalone home located in the heart of the Cannonborough/Elliotborough neighborhood, just two blocks from historic King Street. This prime downtown Charleston location offers painless access to the best eateries, coffee...

  • Charleston
  • 4 Bedrooms
  • 3 Bathrooms
  • Sleeps 8
11 Bedroom Complex- 3 Blocks From King S...

Summary:Welcome to The Palmetto House, a private getaway in the heart of downtown Charleston, SC. This exclusive complex, located within a meticulously remodeled historic home, offers four entirely furnished apartments, creating the ideal getaway...

  • Charleston
  • 11 Bedrooms
  • 8 Bathrooms
  • Sleeps 24
The Madison- Historic Charleston Single ...

Encompass yourself in the history of Charleston by staying in this freshly modernized 1890`s single home. This entire two story home offers guests all the aesthetic features of a Charleston Single House from its enormous double piazzas with blue...

  • Charleston
  • 5 Bedrooms
  • 5 Bathrooms
  • Sleeps 13
Bee & Blossom | Historic Charm

Permit Number: 06191The Space: This former historic Bed and Breakfast has undergone a magical transformation into what is a newly-modernized 6 bedroom/6.5 bath designer's showcase home in the fashionable, laid-back Radcliffborough neighborhood...

  • Charleston
  • 6 Bedrooms
  • 6 Bathrooms
  • Sleeps 12
Harbor Mist House | Spacious 4BR in DT C...

Summary:Welcome to your Charleston getaway, a roomy 4-bedroom home designed for huge groups seeking comfort and convenience. With room for up to 14 guests, this property blends modern amenities with classic Charleston appeal. Whether you’re...

  • Charleston
  • 4 Bedrooms
  • 3 Bathrooms
  • Sleeps 14
Downtown Charleston 8 Bedroom

Recently constructed, three-home complex, centrally located in Downtown Charleston! ✦Over 5,000 SQ FT!! ✦ Great for huge groups - spend time together, but everybody can have their space!✦Open-air porches, welcoming living areas & roomy...

  • Charleston
  • 8 Bedrooms
  • 6 Bathrooms
  • Sleeps 20