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Charleston, SC 4+ Bedroom Vacation Rentals

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361 rentals found
Oak Loft Downtown | Restored Masterpiece

Summary:Welcome to The Oak Loft, an exceptional 4-bedroom, 3-bathroom top floor unit in the heart of Downtown Charleston. With its distinctive design and creative flair, this one-of-a-kind space offers an inspiring getaway! Located just steps from...

  • Charleston
  • 4 Bedrooms
  • 3 Bathrooms
  • Sleeps 8
Luxurious 4 Bedroom, 4.5 Bath Home

Located in the vibrant heart of Charleston`s historic Cannonborough-Elliottborough neighborhood, this roomy and handsome home invites you to experience the appeal and hospitality of the South like never before. Whether you`re here to discover the...

  • Charleston
  • 4 Bedrooms
  • 4 Bathrooms
  • Sleeps 10
Quality Design - Downtown - Steps to Kin...

Summary:Welcome to your Charleston stay in Quality Design, a refined home where artistic touches, thoughtful materials, and walkability combine for a stay that feels both extravagant and local. Ideal for design lovers, couples or group travelers who...

  • Charleston
  • 4 Bedrooms
  • 4 Bathrooms
  • Sleeps 10
Guesthouse Charleston: WEST (62)

At 62 West, you'll feel right at home during your Charleston visit—front porch included! In addition to comfortable beds, this home offers a roomy open-concept living room and kitchen, ideal for entertaining. The charmingly landscaped outdoor...

  • Charleston
  • 4 Bedrooms
  • 4 Bathrooms
  • Sleeps 10
The Chapel | Manor 4BR Charming Charlest...

Summary:Welcome to your Charleston getaway located just moments from King Street, where classic appeal meets modern comfort. This 4-bedroom, 4-bath home is ideal for families or groups who want privacy, ease, and access to Charleston’s best...

  • Charleston
  • 4 Bedrooms
  • 4 Bathrooms
  • Sleeps 10
Charming 4-bedroom home, 10 Minutes to D...

Totally refreshed in 2025 -- Stay comfortably in Charleston at this 4-bedroom home. Each bedroom features a king bed, ensuring a pleasant nighttime's sleep for all guests. With amenities like a washing machine, WiFi, and AC, your stay will be both...

  • Charleston
  • 4 Bedrooms
  • 4 Bathrooms
  • Sleeps 8
The Inns | Grand 9BR Charleston Downtown...

Summary:Welcome to your Charleston gathering place where space meets luxury. This grandiose 9 bedroom home is constructed for sizable groups, offering eight full bathrooms to make everybody’s stay comfortable and convenient. Ideal for family...

  • Charleston
  • 9 Bedrooms
  • 8 Bathrooms
  • Sleeps 16
Marsh front home 10 min to beach and dow...

Welcome to life in the Lowcountry at The Lookout! The design of this home embodies the natural beauty of life on the water with comfort and style. Heated pool just installed! Great place to cool off year round- close to the outdoor TV...

  • Charleston
  • 5 Bedrooms
  • 6 Bathrooms
  • Sleeps 12
Hot Tub • Rooftop • Parking • 3 Bl...

Summary:✨ Welcome to Camellias on Cannon! ????☀️ Private Rooftop Deck & Courtyard with Hot Tub???? 3 Blocks to King St! Walk to Charleston’s Finest Dining, Shopping & Nightlife???? Ideal for Enormous Groups – Families, Wedding Guests...

  • Charleston
  • 8 Bedrooms
  • 7 Bathrooms
  • Sleeps 16
Only 5 blocks to King! | Rose and Petuni...

Permit Number: 06089The Space: Located on Rutledge Avenue in Charleston’s vibrant Cannonborough neighborhood, this newly refreshed 4-bedroom, 4-bath property features two private apartments, ideal for groups who want space, comfort, and...

  • Charleston
  • 4 Bedrooms
  • 4 Bathrooms
  • Sleeps 10
New Historic Home by King St w. Parking!

Summary:Award-winning 4BR/3BA historic Charleston getaway just one block from King Street! This private upstairs home, part of the Revival Street Collection, comfortably sleeps 8+. Features a modern kitchen, dedicated workspace, and a beautiful...

  • Charleston
  • 4 Bedrooms
  • 3 Bathrooms
  • Sleeps 9
Waterfront Oasis w/Ocean Access\nMinutes...

Welcome to a slice of heaven where modern elegance meets unmatched location. This impressive home offers 4 roomy bedrooms, 2 bathrooms, and a lifestyle defined by comfort and serenity. Located on a property that backs onto the elegant Parrot Point...

  • Charleston
  • 4 Bedrooms
  • 2 Bathrooms
  • Sleeps 9
Walk to King St | Sleeps 10 | Rooftop | ...

Summary:Escape to The Spring, a 4-bedroom luxury villa in the heart of Charleston! Just steps from King Street, this getaway offers opulent comfort with three king suites, a private rooftop deck, and walkable access to the city's best attractions...

  • Charleston
  • 4 Bedrooms
  • 3 Bathrooms
  • Sleeps 10
Palm House • Cozy Retreat • Close to...

Summary:Welcome to our 4-bedroom / 2-bathroom guest getaway! Roomy living areas, huge fenced in yard, comfortable interiors, and a short drive to everything will make your trip to Charleston one to remember.Our home has cozy and comfortable living...

  • Charleston
  • 4 Bedrooms
  • 2 Bathrooms
  • Sleeps 8
The Manor by Guesthouse Charleston- Gran...

91A Spring Street is a charmingly restored Victorian Home. This home has 4 bedrooms and 4.5 bathrooms a enormous open living, dining, and kitchen area that opens up to cavernous front porches that overlook the piazza. Each bedroom has a private...

  • Charleston
  • 4 Bedrooms
  • 4 Bathrooms
  • Sleeps 10
Vacation Villa 5 mins to King St ‘The ...

Summary:Vacation Villa 5 min. walk to King St, in the heart of downtown Charleston. This tropical getaway offers sleek design, soaring 25’ ceilings, open first floor kitchen & living room, and roomy bedrooms with en-suite spa bathrooms. The Palm...

  • Charleston
  • 5 Bedrooms
  • 5 Bathrooms
  • Sleeps 14
Patio • Porches • Parking • 2 Bloc...

Summary:✨ Welcome to Azaleas on Spring! ???????? 2 Blocks to King St! Walk to Charleston’s Finest Dining, Shopping & Nightlife???? Ideal for Enormous Groups – Families, Wedding Guests, Bachelor(ettes) & Work Retreats???? Multiple Outdoor...

  • Charleston
  • 7 Bedrooms
  • 7 Bathrooms
  • Sleeps 18
Guesthouse Charleston: SOUTH (105 A & B)

Located peacefully on coveted Spring Street, this striking standalone duplex features eight roomy bedrooms and eight full bathrooms, just steps away from Cannon Green and just three blocks to historic King Street. Ideal for enormous groups or...

  • Charleston
  • 8 Bedrooms
  • 9 Bathrooms
  • Sleeps 20