Charleston-SC.com logo

4+ Bedroom Vacation Rentals

Filter 4+ Bedroom Properties by: Area | Company | Oceanfront | Pet-Friendly | or choose different Bedrooms
No company options available.
Bedrooms:
547 rentals found
The Isla Suite: A Dream Getaway for Frie...

The Isla Suite: A Dream Getaway for FriendsThe Isla Suite is a vibrant first-floor getaway in impressive Charleston, crafted for an memorable friends’ group hideaway. Positioned just steps from downtown’s premier drink bars, top-rated eateries...

  • Charleston
  • 4 Bedrooms
  • 2 Bathrooms
  • Sleeps 8
CLASSIC and Cozy IOP Beach Home, Family-...

Great Family Friendly 5 bedroom home located on a corner lot. Only two blocks from the IOP marina and close to the beach. This home is boat friendly with painless access to the IOP Boat Ramp. You will appreciate how this home can accommodate a very...

  • Isle of Palms
  • 5 Bedrooms
  • 3 Bathrooms
  • Sleeps 12
Brand New Luxury 6 bedrooms, 7.5 bathroo...

Nostos~ 6 51st Ave presented by Exclusive Properties on Isle of Palms. Tired of looking through tons of listings? Do you need a specific type of home or dates? We are a local family owned company, Exclusive Properties, located right here on Isle of...

  • Isle of Palms
  • 6 Bedrooms
  • 7 Bathrooms
  • Sleeps 12
Luxurious Escape in Downtown Charleston ...

Permit Number: 06280The Space: Welcome to Apollo, a cavernous and inviting first-floor getaway offering downtown Charleston living at its best. With 4 bedrooms and 3.5 bathrooms, this home is ideal for families or groups looking for comfort...

  • Charleston
  • 4 Bedrooms
  • 3 Bathrooms
  • Sleeps 9
Ion by AvantStay | Walk to Beach, Dining...

Welcome to Ion, your ideal hideaway near the shores of Sullivan's Island! Just a 10-min. walk (1.5 blocks) from public beach access, this impressive home invites you to relax and savor the coastal lifestyle.Ion features a sprawling backyard and...

  • Sullivans Island
  • 4 Bedrooms
  • 1 Bathrooms
  • Sleeps 10
Beautiful NEW LISTING IOP Waterway Blvd!...

Welcome to your dream coastal hideaway on the Isle of Palms—just 20 mins. north of historic Charleston, SC. This extravagant 4-bedroom, 4.5-bathroom beach getaway offers the ideal blend of Southern appeal and modern comfort, making it ideal for...

  • Isle of Palms
  • 4 Bedrooms
  • 4 Bathrooms
  • Sleeps 8
Wilhelmenia Suites • 4BR Near King •...

Summary:Welcome to The Wilhelmenia Suites, a beautiful and roomy rental just two blocks from King Street in the heart of Charleston. This second floor property features two connected suites with a total of four bedrooms and two bathrooms, ideal for...

  • Charleston
  • 4 Bedrooms
  • 2 Bathrooms
  • Sleeps 12
Casa Zoë | Cabana House – Bold Design...

Summary:OP2025-05859Casa Zoë’s Cabana House is bright, classy, and chic. With well-appointed bedrooms, designer touches throughout, and 3 porches ideal for gathering, it’s ideal for bachelorette weekends or getaways with friends. Appreciate...

  • Charleston
  • 4 Bedrooms
  • 4 Bathrooms
  • Sleeps 11
New Build - Steps to King Street

Feel the epitome of modern Charleston living in this gorgeous, brand new, 5-bedroom, 5-bathroom vacation rental apartment, aptly named The Chateau. Located in the heart of downtown Charleston, this extravagant abode offers an unbeatable location...

  • Charleston
  • 5 Bedrooms
  • 5 Bathrooms
  • Sleeps 14
2 Luxury Houses w/ Patios | 1 Block from...

Summary:Discover luxury pair of completely remodeled luxury homes ideal for a huge group, located next door to each other just moments from King St. Indulge in classy interiors awash with natural light from wrap-around windows. These Charleston...

  • Charleston
  • 8 Bedrooms
  • 7 Bathrooms
  • Sleeps 20
The Saint | Newly Built Charleston Home ...

Summary:Welcome to The Saint, a freshly constructed Charleston home that showcases striking architectural design and modern comfort in a walkable urban setting. Ideal for families, friends, or style-conscious travelers who appreciate light-filled...

  • Charleston
  • 4 Bedrooms
  • 3 Bathrooms
  • Sleeps 12
WILD DUNES Home with PRIVATE POOL, Golf ...

Located the exclusive Yacht Harbor area of Wild Dunes Resort on the Isle of Palms, this gorgeous 4 bedroom, 4.5 bathroom provides the ideal island hideaway. With private pool, golf course vistas, and a short walk to the IOP Marina, it's a...

  • Isle of Palms
  • 4 Bedrooms
  • 4 Bathrooms
  • Sleeps 10
The Gardenia House | Sleeps 20 | Multi-U...

Summary:Welcome to the Gardenia House in the Preserve, a distinguished luxury residence located in the heart of downtown Charleston. This elegant property offers two exclusive suites within a roomy layout of 7 bedrooms and 7 full baths, making it...

  • Charleston
  • 7 Bedrooms
  • 7 Bathrooms
  • Sleeps 20
Guesthouse Charleston: SOUTH 82 B

Apartment with kitchen, 7-min. walk to Medical University of South CarolinaLaundry facilities and Bar-B-Que grilles are available at this smoke-complimentary apartment building. The apartment provides a kitchen with a refrigerator, an oven, a...

  • Charleston
  • 4 Bedrooms
  • 4 Bathrooms
  • Sleeps 10
Abalone Alley 04 - Easy Breezy  - Privat...

4 Abalone Alley- Painless BreezyIsle of PalmsRecently Available with Dunes Properties. Overview:Welcome to Simple Breezy. The name says it all! This completely refreshed 5 bedroom and 4 bath home has top notch finishes in the brand new baths and...

  • Isle of Palms
  • 5 Bedrooms
  • 4 Bathrooms
  • Sleeps 10
Downtown 6BR House with Parking

Summary:Feel The Rose, a attractively refreshed 6-bedroom Charleston classic in the heart of downtown. Uniquely designed for enormous groups, this home features two full kitchens, two living areas, and striking double-decker verandas. With...

  • Charleston
  • 6 Bedrooms
  • 4 Bathrooms
  • Sleeps 16
The Inns - Beautiful 6BR / 6BA - Walk to...

Summary:Welcome to this refined 6-bedroom, 6-bathroom home from The Inns collection. Professionally designed and freshly remodeled, it offers modren comfort mins. from King Street’s vibrant energy, ideal for sizable groups seeking luxury and...

  • Charleston
  • 6 Bedrooms
  • 6 Bathrooms
  • Sleeps 16
Welcome to The Crystal Palace — Perfec...

DOWNTOWN LUXURY — THE CRYSTAL PALACEA restored 1850s Charleston Single glowing with chandeliers in every room, unmatched downtown walkability, fantastic parking, and fast access to Charleston’s best beaches and waterfront dining.The Crystal...

  • Charleston
  • 6 Bedrooms
  • 5 Bathrooms
  • Sleeps 12