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Charleston, SC 4+ Bedroom Vacation Rentals

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361 rentals found
Emerald House | 4BR Charleston Charm Nea...

Summary:Step into a sophisticated getaway where historic touches meet modern design. This 4 bedroom home offers the ideal balance of elegance and comfort, making it an delightful choice for families, groups of friends or business travelers who want...

  • Charleston
  • 4 Bedrooms
  • 3 Bathrooms
  • Sleeps 12
New design & construction, 6 Bed, 6 EnSu...

Welcome to 183 Saint Philip Street, your chic haven in the heart of Charleston! This new construction offers a prime location, placing you steps away from the city's vibrant attractions & best eateries. Each bedroom features 55" Samsung TVs ...

  • Charleston
  • 6 Bedrooms
  • 6 Bathrooms
  • Sleeps 16
6C at Saint Philip Square, One Block to ...

Come experience a luxury stay in the heart of Charleston at Saint Philip Square. Our award-winning collection of historic homes spans nearly one city block, The Aiken House, a 4-bed 4-bath second floor gem that blends modern comfort with...

  • Charleston
  • 4 Bedrooms
  • 4 Bathrooms
  • Sleeps 10
The Barbados House | Luxury House | Slee...

Summary:Welcome to the Barbados House, part of The Preserve, a luxury single-style home located in the heart of downtown Charleston. This elegant 5-bedroom, 5.5-bath residence offers an unparalleled blend of sophisticated appeal and modern comfort...

  • Charleston
  • 5 Bedrooms
  • 5 Bathrooms
  • Sleeps 12
Charming Home w. 4 Beds, Heart of Downto...

Summary:Welcome to The Chapel, your downtown Charleston getaway combining historic appeal, modern amenities, and unbeatable walkability. Ideal for families, groups of friends, or modest gatherings, this 4-bedroom home offers style, comfort, and a...

  • Charleston
  • 4 Bedrooms
  • 4 Bathrooms
  • Sleeps 10
B2 at Saint Philip Square, One Block to ...

Welcome to Saint Philip Square, an award-winning collection of historic homes spanning nearly one city block of downtown Charleston. The Adams Bennett House at 174 B St. Philip St. Unit 2 is a 4 -BD 5- BA second floor gem blends modern comfort with...

  • Charleston
  • 4 Bedrooms
  • 5 Bathrooms
  • Sleeps 14
Spacious James Island 4br/3.5ba House wi...

Welcome to this 4br/3.5ba home located on James Island, only a 10 min drive to Downtown Charleston or a 15 min drive to Folly Beach! Home has 2500sqft of living space on two floors with two living areas so there is plenty of room for everybody to...

  • Charleston
  • 4 Bedrooms
  • 3 Bathrooms
  • Sleeps 12
Downtown Duplex - St Philip St

Feel the timeless appeal of Charleston’s historic peninsula, the Holy City. Stay just mins. from MUSC, the College of Charleston, and the vibrant shopping, dining, and nightlife of King Street. From this ideally located downtown home, you’ll be...

  • Charleston
  • 6 Bedrooms
  • 5 Bathrooms
  • Sleeps 16
4 Bedroom - 2 Blocks to King Street!

Feel the timeless appeal of Charleston’s historic peninsula, the Holy City. Stay just mins. from MUSC, the College of Charleston, and the vibrant shopping, dining, and nightlife of King Street. From this ideally located downtown home, you’ll be...

  • Charleston
  • 4 Bedrooms
  • 2 Bathrooms
  • Sleeps 12
EAST 44 - Entire Home, Only 1 Block to K...

East 44 is a charmingly restored historic home located in the vibrant Cannonborough/Elliotborough neighborhood. Just steps away, you'll find local favorites like Chubby Fish and Island Provisions, striking stores such as The Tiny Tassel and Hermosa...

  • Charleston
  • 4 Bedrooms
  • 4 Bathrooms
  • Sleeps 10
The Chapel | Grand 8BR Charmer - Walkabl...

Summary:Welcome to The Chapel, a delightfully restored 8-bedroom gem in Charleston where character, comfort and convenience come together. Ideal for enormous families or groups, this home offers roomy common areas, charming design details and a...

  • Charleston
  • 8 Bedrooms
  • 8 Bathrooms
  • Sleeps 16
Downtown Charleston Home + Private Pool

Summary:Ideal for a huge family! This listing is for the entire home. The home sleeps 16 guests total. Your stay just got an upgrade. 118B President Street now features a newly finished private plunge pool, sun deck with loungers, and outdoor dining...

  • Charleston
  • 6 Bedrooms
  • 6 Bathrooms
  • Sleeps 16
Plunge Pool|Downtown Oasis|Close to Bars...

Summary:Welcome to The Sullivan & Palm, a charmingly restored Victorian home in the heart of downtown Charleston. This roomy 5-bedroom getaway blends historic appeal with modern amenities, featuring chic living spaces, a chef’s kitchen, and...

  • Charleston
  • 5 Bedrooms
  • 3 Bathrooms
  • Sleeps 12
NEW BUILD | 10 Mins to Folly | 4 BR, 10 ...

Summary:Welcome to Palmetto Pearl! ???? BRAND NEW listing, new photos coming soon!Unwind in this bright and modern NEW CONSTRUCTION home on James Island that sleeps 10 guests with an open layout and a cavernous kitchen and 4 bedrooms. Savor the...

  • Charleston
  • 4 Bedrooms
  • 3 Bathrooms
  • Sleeps 10
4 Bedroom - 4 Blocks to King St. with Pa...

Feel the timeless appeal of Charleston’s historic peninsula, the Holy City. Stay just mins. from MUSC, the College of Charleston, and the vibrant shopping, dining, and nightlife of King Street. From this ideally located downtown home, you’ll be...

  • Charleston
  • 4 Bedrooms
  • 2 Bathrooms
  • Sleeps 10
4BR/4BA Historic + Modern - 2 Units - Wa...

Welcome to the Holy City, and the historic southern appeal of the Charleston peninsula. Our Vacation Rental By Owner is located in handsome downtown Charleston and just mins. away from MUSC, the College of Charleston, and King Street’s shopping...

  • Charleston
  • 4 Bedrooms
  • 4 Bathrooms
  • Sleeps 10
The Rosemary House | Sleeps 16 | Multi-U...

Summary:Welcome to the Rosemary House at The Preserve, a cavernous and elegantly appointed residence occupying the top floors of a gorgeously preserved historic home. With 8 bedrooms and 8 bathrooms, this broad property offers ample privacy and...

  • Charleston
  • 7 Bedrooms
  • 7 Bathrooms
  • Sleeps 16
The Grand Helène - Newly Renovated 11BD...

Summary:Recently constructed 11BR/11.5BA home in the laid-back Cannonborough/Elliotborough neighborhood—ideal for sizable groups seeking space and privacy. The property features three separate units in one building, ideal for gathering together...

  • Charleston
  • 11 Bedrooms
  • 12 Bathrooms
  • Sleeps 22