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Charleston, SC 4+ Bedroom Vacation Rentals

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340 rentals found
Spacious Charleston Home: Only 3 Mi to F...
3.7
(17)

Make this 5-bedroom, 3-bathroom vacation rental your home base as you discover all Charleston has to offer. The 'James Island Folly Family Retreat' includes 3,000 square feet of living space, ideal for a huge family or a couple of smaller ones. The...

  • Charleston
  • 5 Bedrooms
  • 3 Bathrooms
  • Sleeps 10
Large Charleston Family Home with Pool! ...

Looking for space to comfortably home a enormous family? Same! If you're looking for a comfortable, clean family home, let our family show yours some Southern hospitality! Just mins. to downtown Charleston, this home is located in the West Ashley...

  • Charleston
  • 5 Bedrooms
  • 3 Bathrooms
  • Sleeps 9
Thomas Waring House | Unit A | Sleeps 11

Summary:Welcome to Thomas Waring House-Suite A at The Preserve, a historic and award-winning residence that offers a unique blend of appeal and modern convenience. This luxury suite in downtown Charleston is comprised of 5 bedrooms and 5.5...

  • Charleston
  • 5 Bedrooms
  • 5 Bathrooms
  • Sleeps 11
Poolside Paradise Getaway | North Charle...

Summary:Feel a calming and fresh getaway in our gorgeously appointed five-bedroom, three-bathroom single-family home in North Charleston. Designed with discerning guests in mind, this property offers modern amenities and refined amenities, making it...

  • Charleston
  • 5 Bedrooms
  • 3 Bathrooms
  • Sleeps 12
Vacation Villa (ADA) 'The Mediterranean ...
5.0
(3)

Summary:Vacation Villa 5 min. walk to King St, in the heart of downtown Charleston. This tropical getaway offers sleek design, open first floor kitchen & living room, & cavernous bedrooms with en-suite spa bathrooms. Unwind in luxury at...

  • Charleston
  • 4 Bedrooms
  • 4 Bathrooms
  • Sleeps 10
Great Downtown Charleston Location!
5.0
(60)

Feel what it means to live like a local in our 2-story Downtown Charleston home. This home is 6 beds / 5.5 baths and would be ideal for enormous groups/families of up to 12 people. Located 1 block off King Street, you can walk to eateries, bakeries...

  • Charleston
  • 6 Bedrooms
  • 5 Bathrooms
  • Sleeps 12
Whole House|Downtown|Sleeps 16

Summary:Welcome to The Ivory and Oak Lofts, a gorgeous 8-bedroom, 6-bathroom historic home located in the heart of Charleston. This delightfully restored property blends timeless appeal with modern amenities, offering an exceptional space for...

  • Charleston
  • 8 Bedrooms
  • 6 Bathrooms
  • Sleeps 16
Charming Avondale Home ~ 5 min from Down...

Welcome to this 3br/2ba home in the highly charming Avondale neighborhood West of the Ashley. In a ideal location only 5 mins. walk to the eateries/bars of Avondale and the West Ashley Greenway and less than a 10 min. drive to Downtown Charleston...

  • Charleston
  • 4 Bedrooms
  • 2 Bathrooms
  • Sleeps 7
4 Bedroom - 2 Blocks to King Street!

Welcome to the Holy City, and the historic southern appeal of the Charleston peninsula. Our Vacation Rental By Owner is located in striking downtown Charleston and just mins. away from MUSC, the College of Charleston, and King Street’s shopping...

  • Charleston
  • 4 Bedrooms
  • 2 Bathrooms
  • Sleeps 12
NEW! Private Home Downtown at Emerson Sq...

Summary:Welcome to your Full Private Home Retreat in Downtown Charleston! This gorgeous 4-bedroom, 3.5-bathroom luxury residence is a freshly constructed masterpiece, professionally furnished and designed with every detail in mind. Located in the...

  • Charleston
  • 4 Bedrooms
  • 3 Bathrooms
  • Sleeps 10
Harleston House | Unit A | Sleeps 10

Summary:Welcome to the Harleston House in the Preserve, a classy 4-bedroom, 4-bathroom luxury suite in downtown Charleston. This modern getaway, complete with modern furnishings and a private plunge pool, offers an exclusive escape for guests...

  • Charleston
  • 4 Bedrooms
  • 4 Bathrooms
  • Sleeps 10
Downtown Duplex - St Philip St - Sleeps ...
5.0
(2)

This pair of delightfully restored Charleston Singles is offered as a package for bigger events. The property is centrally located in the heart of historic downtown Charleston, just a short walk from acclaimed eateries, venues and trendy...

  • Charleston
  • 6 Bedrooms
  • 5 Bathrooms
  • Sleeps 16
*NEW*Charleston Chic: Modern 4BR Downtow...

Summary:BRAND NEW! The Charlee on Cannon is a haven of luxury, tranquility, and rejuvenation located right in the middle of Charleston’s pulse. Featuring 4 bedrooms, 3 baths, an chic open-concept living space and sizable balcony with plenty of...

  • Charleston
  • 4 Bedrooms
  • 3 Bathrooms
  • Sleeps 10
Parlour Brighton | Two Homes | Perfect f...

The Space: This rental is two seperate homes next to each other.As you walk into The Parlor home from the first floor piazza, you are greeted by an opulent entry entryway with the home’s open living room and kitchen to the right. The living room...

  • Charleston
  • 6 Bedrooms
  • 6 Bathrooms
  • Sleeps 13
Penthouse with Courtyard - 1 BLOCK TO KI...
4.5
(2)

Summary:Welcome to "The Palms of Charleston" - this historic home with a striking enormous courtyard is just one block to King St!- Stunning, sizable courtyard and private porch with wicker seating- Walk to the best eateries, nightlife, and...

  • Charleston
  • 4 Bedrooms
  • 2 Bathrooms
  • Sleeps 8
Casa Zoë | Cabana House – Bold Design...
4.8
(93)

Summary:Casa Zoë’s Cabana House is bright, modren, and chic. With well-appointed bedrooms, designer touches throughout, and 3 porches ideal for gathering, it’s ideal for bachelorette weekends or getaways with friends. Appreciate walkable...

  • Charleston
  • 5 Bedrooms
  • 4 Bathrooms
  • Sleeps 11
New! Historic Residence – Great For La...

Summary:Welcome to Emerson Square Charleston, a enormous and professionally designed residence that seamlessly blends Charleston’s rich history with modern luxury. Spanning the entire second and third floors of a meticulously restored historic...

  • Charleston
  • 5 Bedrooms
  • 4 Bathrooms
  • Sleeps 14
Quiet house by beautiful park, steps fro...

Stunning, light-filled home in historic downtown Charleston! Located in the trendy Wagener Terrace neighborhood, steps from elegant Hampton Park and a fast bicycle ride (or 30 min walk) from King Street, the heart of Charleston, with its eateries...

  • Charleston
  • 4 Bedrooms
  • 2 Bathrooms
  • Sleeps 5