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Charleston, SC 4+ Bedroom Vacation Rentals

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357 rentals found
Stunning 6-Bedroom Home with Pool, 5.5 B...

More photos coming soon!Dive in to this newly refreshed 6-bedroom, 5.5 bathroom home with a brand new pool, ideal for hosting up to 12 guests. This three-story haven, adorned with wood floor, original fireplaces, and high ceilings with exposed...

  • Charleston
  • 6 Bedrooms
  • 5 Bathrooms
  • Sleeps 12
Luxury 4bd French Quarter Retreat w. Par...

Summary:Welcome to your freshly modernized 4BR/3BA luxury getaway in Charleston’s historic French Quarter. Ideal for families and group getaways, this 3,000 sq. ft. home sleeps 14 guests and features soaring ceilings, exposed brick, a chef’s...

  • Charleston
  • 4 Bedrooms
  • 3 Bathrooms
  • Sleeps 14
B1 at Saint Philip Square, One Block to ...

Welcome to Saint Philip Square, an award-winning collection of historic homes spanning nearly one city block of downtown Charleston. The Adams Bennett House at 174 B#1 Saint Philip Street is a 4-bed 4-bath first floor gem that blends modern comfort...

  • Charleston
  • 4 Bedrooms
  • 4 Bathrooms
  • Sleeps 10
Guesthouse Charleston: SOUTH (82 A & B)

82 A & B is a cavernous two-story home, attractively located within walking distance of Charleston's best eateries, bars, and attractions. Ideal for sizable groups, the home features two entirely equipped kitchens, two living areas, and multiple...

  • Charleston
  • 8 Bedrooms
  • 9 Bathrooms
  • Sleeps 18
Luxury 4BR, Parking, Outdoor Space

Summary:Feel Charleston in style at this luxury 4-bed, 3-bath downtown suite. Professionally designed, this roomy first-floor getaway comfortably sleeps 8+. This property consists of the entire downstairs unit of a two unit property. Features a...

  • Charleston
  • 4 Bedrooms
  • 3 Bathrooms
  • Sleeps 10
Hot Tub Haven • Parking • Walk to Ki...

Summary:Welcome to Camellias on Cannon - Suite A!☀️ Shared Courtyard with Hot Tub???? 3 Blocks to King St! Walk to Charleston’s Finest Dining, Shopping & Nightlife???? Ideal for Sizable Groups – Families, Wedding Guests, Bachelor(ettes) ...

  • Charleston
  • 4 Bedrooms
  • 4 Bathrooms
  • Sleeps 8
Great for Groups | Private Patio | The Z...

Permit Number: 06281The Space: Welcome to Zeus — a freshly redesigned second-floor getaway constructed for comfortable group stays. With 5 bedrooms and 4.5 bathrooms across two upper levels, this roomy home gives families and bigger groups room to...

  • Charleston
  • 5 Bedrooms
  • 4 Bathrooms
  • Sleeps 12
Lowcountry Charm | 4BR Spring St. Home w...

Welcome to the Holy City, and the historic southern appeal of the Charleston peninsula. Our Vacation Rental By Owner is located in elegant downtown Charleston and just mins. away from MUSC, the College of Charleston, and King Street’s shopping and...

  • Charleston
  • 4 Bedrooms
  • 3 Bathrooms
  • Sleeps 11
The Jessamine | 9BR Historic Downtown Ab...

Summary:Welcome to your Cannonborough hideaway, a newly refreshed 3-unit property just one block from iconic King Street. Ideal for families or groups of friends, this getaway blends comfort, style, and convenience. With updated interiors, a calming...

  • Charleston
  • 9 Bedrooms
  • 5 Bathrooms
  • Sleeps 16
Newly Renovated 4BR 2BA Walk to King Str...

Feel the timeless appeal of Charleston’s historic peninsula, the Holy City. Stay just mins. from MUSC, the College of Charleston, and the vibrant shopping, dining, and nightlife of King Street. From this ideally located downtown home, you’ll be...

  • Charleston
  • 4 Bedrooms
  • 2 Bathrooms
  • Sleeps 10
The Trio at 493 - 3 Suites - On King!

Permit Number: 004141The Space: Welcome to 493 Luxury Suites! These charmingly appointed units are found on the second floor of a historic building on King Street (above Sewing Down South, as seen on “Southern Charm”).Step into the building...

  • Charleston
  • 6 Bedrooms
  • 6 Bathrooms
  • Sleeps 18
Full Renovation of 1811 historical home....

Recently restored and only 2 blocks from the heart of the entertainment district of Upper King Street, Stay Cannon is the ideal landing place for your next trip to Charleston.Stay Cannon is a legally allowed vacation rental as required by Charleston...

  • Charleston
  • 6 Bedrooms
  • 6 Bathrooms
  • Sleeps 12
Sunny Haven Retreat near Folly w/ Backya...

Discover a comfortable coastal escape conveniently located just mins. from Folly Beach or Downtown Charleston! Our appealing 4br/2ba home is the ideal getaway, featuring a refreshed interior that has been charmingly decorated. Appreciate the...

  • Charleston
  • 4 Bedrooms
  • 2 Bathrooms
  • Sleeps 8
Historic Boutique Home ‘The Palms’

Summary:A short walk from King St. 'The Palms' is a roomy private historic property. The property offers an open kitchen & living area, opening directly to traditional southern piazza. Plenty of space for guests to relax. Property amenities also...

  • Charleston
  • 4 Bedrooms
  • 4 Bathrooms
  • Sleeps 9
The Manor on Spring 91 B- Immaculately R...

The true Charleston experience awaits at The Manor at 91B Spring, a restored Victorian home in the heart of the city. The home offers 4 bedrooms plus a flex room with a queen Murphy bed, along with 4.5 bathrooms, including 3 ensuites. A bright, open...

  • Charleston
  • 4 Bedrooms
  • 4 Bathrooms
  • Sleeps 12
5BR Charleston Oasis w/ Screened Porch f...

Why you`ll appreciate The TropicFive roomy bedrooms, with a master that treats you to a king bed and rainfall shower. Parlor year-round on the humongous screened porch, or fire up the grille in your private jungle yard with a dining deck under the...

  • Charleston
  • 5 Bedrooms
  • 2 Bathrooms
  • Sleeps 12
Charleston Duplex Home 5BR - Walk to Kin...

Welcome to the Holy City, and the historic southern appeal of the Charleston peninsula. Our Vacation Rental By Owner is located in gorgeous downtown Charleston and just mins. away from MUSC, the College of Charleston, and King Street’s shopping...

  • Charleston
  • 5 Bedrooms
  • 3 Bathrooms
  • Sleeps 10
Ivy Manor | DT Oasis + Carriage House!

Summary:Welcome to your Charleston getaway where artistry meets comfort and privacy. This stay features a main home plus a private carriage home, offering space, style, and a sense of getaway. Ideal for families or groups wanting design-forward...

  • Charleston
  • 8 Bedrooms
  • 4 Bathrooms
  • Sleeps 16