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Charleston, SC 4+ Bedroom Vacation Rentals

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361 rentals found
Downtown Duplex - Rutledge Avenue

Feel the timeless appeal of Charleston’s historic peninsula, the Holy City. Stay just mins. from MUSC, the College of Charleston, and the vibrant shopping, dining, and nightlife of King Street. From this ideally located downtown home, you’ll be...

  • Charleston
  • 4 Bedrooms
  • 2 Bathrooms
  • Sleeps 12
St. Philip Collection - Pair of newly re...

This listing is combined of two traditional style Charleston row homes with great outdoor space. The two homes are directly beside each other and have their own separate entrances. Each home has plenty of space to all gather together may it be...

  • Charleston
  • 5 Bedrooms
  • 6 Bathrooms
  • Sleeps 14
Patio • Porches • Parking • Walk t...

Summary:Welcome to Azaleas on Spring!☀️ Private Hot Tub???? 2.5 Blocks to King St – Walk to Charleston’s Finest Dining, Shopping & Nightlife???? Ideal for Sizable Groups – Families, Weddings, & Work Retreats???? Multiple Outdoor Spaces –...

  • Charleston
  • 7 Bedrooms
  • 7 Bathrooms
  • Sleeps 18
Charming Charleston Getaway

Welcome to your home away from home in the heart of Charleston`s vibrant Cannonborough-Elliottborough neighborhood! This cavernous 4 bedroom, 3.5 bathroom getaway is ideal for families or groups of friends looking to discover all that this historic...

  • Charleston
  • 4 Bedrooms
  • 3 Bathrooms
  • Sleeps 10
Charleston Abode | Downtown, 1 Block fro...

Summary:Welcome to Charleston Abode, a luminous 2-bedroom getaway just one block from King Street where historic appeal meets modern comfort. Designed for couples or modest groups, this home offers airy interiors, classy details, and rare outdoor...

  • Charleston
  • 6 Bedrooms
  • 4 Bathrooms
  • Sleeps 14
4BR Group Retreat, Walk to King St

Summary:Welcome to Blue Magnolia, a roomy and charmingly designed Charleston getaway ideally suited for family vacations, group getaways, wedding weekends, and special celebrations. Located in the heart of downtown Charleston, this inviting home...

  • Charleston
  • 4 Bedrooms
  • 2 Bathrooms
  • Sleeps 10
Casa Zoë | Cottage Row – Side-by-Side...

Summary:OP2025-05857OP2025-05858Cottage Row is a rare Charleston find with two entirely separate, next-door Casa Zoë cottages that together create the ideal setup for groups who want to be close but still have their own space. Tucked in the...

  • Charleston
  • 4 Bedrooms
  • 4 Bathrooms
  • Sleeps 10
Charleston Duplex Home 5BR - Walk to Kin...

Welcome to the Holy City, and the historic southern appeal of the Charleston peninsula. Our Vacation Rental By Owner is located in striking downtown Charleston and just mins. away from MUSC, the College of Charleston, and King Street’s shopping...

  • Charleston
  • 5 Bedrooms
  • 3 Bathrooms
  • Sleeps 10
Rare, Historical Estate near Market St w...

Summary:The Jacob Rabb House (circa 1851) sits in the esteemed Ansonborough neighborhood in the heart of the Historic District of Charleston. Walk to the city’s best dining and landmarks, then getaway to this handsome three-story home with a...

  • Charleston
  • 4 Bedrooms
  • 4 Bathrooms
  • Sleeps 8
Full House w Bikes, Grill + Patio + Park...

Summary:This home has everything you need for the ideal group trip to Charleston. Located in the heart of Downtown in a safe, charming neighborhood, The Rose features six handsomely refreshed bedrooms, two full kitchens, and two cavernous living...

  • Charleston
  • 6 Bedrooms
  • 4 Bathrooms
  • Sleeps 16
STEPS to King St - 6 Bedroom Home - Spac...

Summary:Welcome to your Charleston escape, a generously sized 6-bedroom home constructed for big groups who want to be in the heart of the action yet appreciate broad living spaces. Ideal for family get-togethers or friend get-togethers, this home...

  • Charleston
  • 6 Bedrooms
  • 6 Bathrooms
  • Sleeps 16
Stunning 6-Bedroom Home with Pool, 5.5 B...

More photos coming soon!Dive in to this freshly modernized 6-bedroom, 5.5 bathroom home with a brand new pool, ideal for hosting up to 12 guests. This three-story haven, adorned with wood floor, original fireplaces, and high ceilings with exposed...

  • Charleston
  • 6 Bedrooms
  • 5 Bathrooms
  • Sleeps 12
Luxurious Waterfront Getaway, minutes fr...

This Waterfront, 5 Bedroom / 5 Bathroom home on Oak Island is 100% gut refreshed, mins. from Folly Beach and is the ideal hideaway for families and friends. All bedrooms have king size beds. The home features two kitchens both entirely equipped. ...

  • Charleston
  • 5 Bedrooms
  • 5 Bathrooms
  • Sleeps 8
Charleston Charm - Downtown - 4 Bedroom

Summary:Welcome to Charleston Charm, your home away from home located in the historic Westside neighborhood. Savor the best of Charleston from this appealingly located getaway, just steps from RiverDogs Stadium, The Citadel, and Daps Breakfast ...

  • Charleston
  • 4 Bedrooms
  • 3 Bathrooms
  • Sleeps 9
Professionally Designed 5bd Retreat, Ste...

Summary:Welcome to Emerson Square, a grandiose professionally designed getaway of a delightfully restored historic building, this broad five-bedroom residence is ideal for families and sizable groups. Appreciate a chef’s kitchen, SMART TVs...

  • Charleston
  • 5 Bedrooms
  • 4 Bathrooms
  • Sleeps 15
4BR Charleston Single! One Block to King...

Summary:Welcome to your Charleston getaway, a delightfully preserved 4-bedroom Charleston Single home that combines historic appeal, generous proportions, and a premier location just one block from King Street.Tag us in your post! Check us out on...

  • Charleston
  • 4 Bedrooms
  • 4 Bathrooms
  • Sleeps 12
Newly Restored Historic Home, Close to K...

Welcome to 12 Cannon Street, Units A & B – a gorgeously restored four-bedroom, six-bathroom Charleston-style home in the heart of the city. This combined listing is ideal for bigger families and groups seeking modern amenities within walking...

  • Charleston
  • 4 Bedrooms
  • 6 Bathrooms
  • Sleeps 12
Ivory Loft Downtown, Close to Shops & Re...

Summary:Welcome to The Ivory Loft, a chic 4-bedroom, 3-bathroom lower level unit located in the heart of Downtown Charleston. This thoughtfully designed space blends modern aesthetics with artistic flair, offering a comfortable and unique getaway...

  • Charleston
  • 4 Bedrooms
  • 3 Bathrooms
  • Sleeps 8