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4+ Bedroom Vacation Rentals

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551 rentals found
Historic Charm | The Bee & Blossom

Permit Number: 06191The Space: Welcome to The Bee and Blossom, a delightfully reimagined historic 6-bedroom, 6.5-bath home in the laid-back Radcliffborough neighborhood, thoughtfully designed for groups of up to twelve guests!Spanning three...

  • Charleston
  • 6 Bedrooms
  • 6 Bathrooms
  • Sleeps 12
Third Floor Private Sundeck! | The Posei...

Permit Number: 06282The Space: Welcome to The Poseidon — a roomy downtown getaway just off Spring Street. With 5 bedrooms, 3.5 baths, and an open layout constructed for gathering, it’s an ideal setup for families and bigger groups.Cozy. Central...

  • Charleston
  • 5 Bedrooms
  • 3 Bathrooms
  • Sleeps 10
NEW Home | Close to DT & Beaches | 4 BR,...

Summary:Welcome to Coastal Comfort!Unwind in this bright and modern new construction home. It features a roomy kitchen, four comfortable bedrooms, and a beach-inspired design. Appreciate the sizable backyard for gatherings, and make this your ideal...

  • Charleston
  • 4 Bedrooms
  • 2 Bathrooms
  • Sleeps 10
The Inns | Luxury Design w. Speakeasy Ba...

Summary:Surrounded by swaying Spanish moss in one of Charleston’s most photogenic neighborhoods, this impressive 7-bedroom, 5-bath home captures the essence of Southern grace with a modern twist. Thoughtfully refreshed in September 2025, every...

  • Charleston
  • 7 Bedrooms
  • 5 Bathrooms
  • Sleeps 14
Modernized 5BR Family Home?Tranquil Pati...

This handsome 5-bedroom, 2.5-bathroom home is a true gem, located on one of the quietest streets in Charleston. With freshly refreshed bathrooms, resurfaced floors, and a cavernous, open floor plan, this home is ideal for families or professionals...

  • Charleston
  • 5 Bedrooms
  • 3 Bathrooms
  • Sleeps 10
Full Renovation of 1811 historical home....

Recently restored and only 2 blocks from the heart of the entertainment district of Upper King Street, Stay Cannon is the ideal landing place for your next trip to Charleston.Stay Cannon is a legally allowed vacation rental as required by Charleston...

  • Charleston
  • 6 Bedrooms
  • 6 Bathrooms
  • Sleeps 12
Vacation Villa 5 mins to King 'Travelers...

Summary:Vacation Villa 5 min. walk to King St, in the heart of downtown Charleston. This tropical getaway offers sleek design, soaring 25’ ceilings, open first floor kitchen & living room, and roomy bedrooms with en-suite spa bathrooms. The Palm...

  • Charleston
  • 5 Bedrooms
  • 5 Bathrooms
  • Sleeps 14
Lagoon view, screen porch w/ swing bed, ...

All 2025 reservation will receive $250 credit toward beach gear units with VayK Life! *3-21 nights onlyIncredible 4 BR home with simple beach access just outside of the Pelican Bay neighborhood in Wild Dunes. Totally modernized with brand new...

  • Isle of Palms
  • 4 Bedrooms
  • 3 Bathrooms
  • Sleeps 8
Luxurious 6bd Isle of Palms Home with PO...

WELCOMING RENTERS BEGINNING mid-MARCH 2026! --MORE PHOTOS COMING SOON--Welcome to your ideal Isle of Palms escape at 23 26th Avenue—a striking home designed for effortless coastal living. Ideally located just one block from the Isle of Palms...

  • Isle of Palms
  • 6 Bedrooms
  • 4 Bathrooms
  • Sleeps 14
POOL and HOT TUB! Waterway and Golf View...

Looking for the ideal home for your next Charleston beach vacation? You found it! Welcome to Heads Carolina at 3101 Waterway, one of our most trendy listings!Some of our favorite features:Waterway, Golf and Sunset VistasPrivate Pool with Hot Tub...

  • Isle of Palms
  • 4 Bedrooms
  • 3 Bathrooms
  • Sleeps 10
5BR Rooftop Home with Parking Near King ...

Summary:Discover 'Palmetto on Spring | Rooftop Suite,' a striking 5-bed, 5.5-bath Charleston getaway. This remodeled home spans three floors, featuring a detached guesthouse and a private rooftop terrace with city vistas. Ideal for huge groups, it's...

  • Charleston
  • 5 Bedrooms
  • 5 Bathrooms
  • Sleeps 12
Perfect family home in West Ashley, minu...

PROMO 5% WEEKLY DISCOUNT!Welcome to your home away from home while in Charleston. Our 2000 square foot home is located in a peaceful neighborhood, encompassed in the beauty of Low Country Marshes in West Ashley. We have lovingly modernized the home...

  • Charleston
  • 4 Bedrooms
  • 2 Bathrooms
  • Sleeps 8
Oak Loft Downtown | Restored Masterpiece

Summary:Welcome to The Oak Loft, an exceptional 4-bedroom, 3-bathroom top floor unit in the heart of Downtown Charleston. With its distinctive design and creative flair, this one-of-a-kind space offers an inspiring getaway! Located just steps from...

  • Charleston
  • 4 Bedrooms
  • 3 Bathrooms
  • Sleeps 8
Luxurious Escape in Downtown Charleston ...

Permit Number: 06280The Space: Welcome to Apollo — a cavernous first-floor getaway designed for casual downtown living. With 4 bedrooms and 3.5 bathrooms all on one level, this home offers an simple layout for families and groups who want comfort...

  • Charleston
  • 4 Bedrooms
  • 3 Bathrooms
  • Sleeps 9
EAST 46 G & H - 2 Units, Connected Inter...

Two splendid adjoining apartments offering a total of 5 bedrooms, 5 bathrooms, 2 full kitchens, and 2 roomy living rooms, making them ideal for bigger groups or families seeking both space and comfort. Located just one block from King Street in...

  • Charleston
  • 5 Bedrooms
  • 5 Bathrooms
  • Sleeps 14
Luxury 8BR/6.5BA Downtown w Outdoor Spac...

Summary:Bring everybody together in this roomy 8BR/6.5BA Charleston home featuring two kitchens, dual living areas, and chic design throughout. Just 4 blocks from King Street, this getaway offers modern amenities with historic appeal, high-speed...

  • Charleston
  • 8 Bedrooms
  • 6 Bathrooms
  • Sleeps 18
IOP w/ Private POOL, RENOVATED, Walk to ...

Centrally located on the spectacular Isle of Palms just outside of historic Charleston, this handsome 5-bedroom home on 22nd Avenue is the ideal place to savor a family beach vacation! Renovated in 2021, this home provides a modern, upgraded twist...

  • Isle of Palms
  • 5 Bedrooms
  • 3 Bathrooms
  • Sleeps 12
Second row back from the beach, cornhole...

As of 10/30/2025 construction is now happening behind the home. One row back from the beach! This ocean view, 9 bedroom 6 and a half bath home is loaded with amenities for your family getaway. Charm and coastal style are found throughout this...

  • Isle of Palms
  • 9 Bedrooms
  • 6 Bathrooms
  • Sleeps 20