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Charleston, SC 2+ Bedroom Vacation Rentals

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1067 rentals found
4BR/4BA Historic + Modern - 2 Units - Wa...

Welcome to the Holy City, and the historic southern appeal of the Charleston peninsula. Our Vacation Rental By Owner is located in striking downtown Charleston and just mins. away from MUSC, the College of Charleston, and King Street’s shopping...

  • Charleston
  • 4 Bedrooms
  • 4 Bathrooms
  • Sleeps 10
Peaceful Porch + Parking - 2 Blocks to K...

Summary:✨ Welcome to Azaleas on Spring – Suite A! ????Notable amenities include:???? Porch overlooking historic Spring St???? 2 Blocks to King St – Walk to Charleston’s Finest Dining, Shopping & Nightlife????️ 3 King Bedrooms + 3 Ensuite...

  • Charleston
  • 3 Bedrooms
  • 3 Bathrooms
  • Sleeps 6
Downtown Charleston Peninsula Home

Monthly rental in downtown Charleston Historic Charleston Cottage just 1 block from the heart of King and Market Street. Our 1000sf two bedroom/two bath home has newly been remodeled and furnished to include all new high-end linens and furnishings...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 8
Casa Bella Suite B | 3 Blocks to King St...

Permit Number: OP2025-06240The Space: Welcome to Casa Bella B, a warm and modren second-floor getaway in the heart of downtown Charleston. Thoughtfully remodeled and full of natural light, this inviting home places you just steps from beloved local...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 6
The Charleston Suites: The Victoria Suit...

The Victoria Suite>> Prime Location: Ideal escape from busy streets>> Quick walk to beverages, dinner + shopping>> 20 min drive to the beach>> Extensive piazza w/ seating>> Professionally turfed shared backyard w/ pergola + grille>> Beds for 6...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 6
EAST 46 E - Ground Floor Unit!

Located just one block off King Street in the vibrant Cannonborough/Elliotborough neighborhood, East 46 - E is a classy 2-bedroom, 2-bath ground-floor apartment. Savor simple access to local eateries, stores, coffee stores, and everything downtown...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 6
8 Bedroom - Close to King Street - with ...

Feel the timeless appeal of Charleston’s historic peninsula, the Holy City. Stay just mins. from MUSC, the College of Charleston, and the vibrant shopping, dining, and nightlife of King Street. From this ideally located downtown home, you’ll be...

  • Charleston
  • 8 Bedrooms
  • 4 Bathrooms
  • Sleeps 16
Luxury Two Bedroom Residence with Outdoo...

The Pinch Hotel offers completely outfitted guestrooms, luxury amenities from check-in to check-out, and an ambiance of warmth and surprise, The Pinch is a touch of high culture in the Lowcountry. Let us redefine what a luxury, boutique hotel can...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 4
The Pink Palmetto-Walk To King!

Welcome to The Pink Palmetto – your chic Charleston hideaway! This super trendy two-story home features 2 roomy bedrooms with king beds, plus a comfortable full-sized couch sleeper, making it the ideal spot for a girls’ trip, friends’...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 6
10min to Downtown - Bring your dog & boa...

Welcome to our home! Located in the heart of West Ashley, a vibrant suburb of Charleston, SC.Located in a well-established neighborhood, this home offers simple access to all the delights of Charleston living. Only 6 miles from downtown Charleston...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 10
The Congaree Cottage | Cozy 2BR Carriage...

Summary:Welcome to your Charleston home away from home, a comfortable 2-bedroom carriage home made for families who value comfort, convenience, and thoughtful amenities. Whether you’re traveling with little ones or simply want a getaway where you...

  • Charleston
  • 2 Bedrooms
  • 1 Bathrooms
  • Sleeps 5
Hibiscus House: Embrace Comfort and Conv...

Permit Number: 06760The Space: ???? Welcome to 'The Hibiscus House' - Your Ideal Getaway! ???????? Ideal for groups up to 6 guests with 3 bedrooms, 2 full baths, and 1 half bath.???? Perfectly located just off Cannon Street, and worry not about...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 6
Deluxe Two Bedroom Suite - Steps to King...

Summary:Feel the appeal of historic downtown Charleston in this luxury two-bedroom gem opening onto King Street. Each bedroom features an ensuite bathroom for your comfort and privacy. Appreciate the modern open floor plan, complete with a gourmet...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 4
North Central, 30-Day Rental Home w/Doub...

Summary:1 Francis - 30 Day RentalThe Space:An ideal, beautiful space for a summer vacation, a winter escape, or short-term housing for a long-term relocation, this two-bedroom home will place you within painless striking distance of the very best of...

  • Charleston
  • 2 Bedrooms
  • 1 Bathrooms
  • Sleeps 4
Renovated 3 Bedroom Home Right Off King ...

**30 Day Rental**Make the most of your visit to Charleston, the world`s top travel destination, by staying in a roomy two story row home in the heart of downtown. All furnishings is brand new along with new appliances and wood floors! This home is...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 8
Primrose Home: Tradition with a Modern T...

Permit Number: 06291The Space: · 2 Bedrooms, 1 Bath: Savor a peaceful stay with two inviting bedrooms and a shared, opulent bathroom with a walk-in shower on the second floor.· Historic Charm: Step into our 1835 home, a comfortable getaway in the...

  • Charleston
  • 2 Bedrooms
  • 1 Bathrooms
  • Sleeps 4
Newly Renovated Charleston Ranch | 4BR, ...

Summary:Feel true Charleston appeal in this freshly remodeled Marsh Front getaway. Ideal for families or groups who want comfort and privacy. This home sits on .5 acres and is surrounded by impressive Oak Trees. You will adore how peaceful and safe...

  • Charleston
  • 4 Bedrooms
  • 2 Bathrooms
  • Sleeps 8
Charming South of Broad Kitchen House

I find it necessary to reserve the right to ask for identification prior to reserving. I am now going from instant booking to a 24 hour period to ascertain that you can provide identification should that be necessary. I am aware that unlike Airbnb...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 4