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Charleston, SC 2+ Bedroom Vacation Rentals

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1064 rentals found
Green Cottage – Private Casa Zoë Down...

Summary:OP2025-05858Green Cottage is your own private Charleston hideaway - historic appeal meets Casa Zoë’s modern elegance. Recently redesigned with two bedrooms and two baths, it’s a ideal blend of comfort and design, tucked just steps from...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 5
Queen Kelsey-Mins From Credit One-Pet Fr...

Master Bedroom: 1 King BedGuest Bedroom: 2 Full Beds, 1 Bunk Bed with 2 twinsPack and Play supplied*Please Note: We operate our homes like a luxury hotel, just check in with a code and leave your towels on the floor when you check out. We take care...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 8
Downtown Duplex - Coming St - Sleeps 20

Feel the timeless appeal of Charleston’s historic peninsula, the Holy City. Stay just mins. from MUSC, the College of Charleston, and the vibrant shopping, dining, and nightlife of King Street. From this ideally located downtown home, you’ll be...

  • Charleston
  • 6 Bedrooms
  • 4 Bathrooms
  • Sleeps 16
Guesthouse Charleston: SOUTH (105 A & B)

Located peacefully on coveted Spring Street, this striking standalone duplex features eight roomy bedrooms and eight full bathrooms, just steps away from Cannon Green and just three blocks to historic King Street. Ideal for sizable groups or...

  • Charleston
  • 8 Bedrooms
  • 9 Bathrooms
  • Sleeps 20
Just Blocks from King St | Sweetgrass (S...

Permit Number: 06474The Space: Welcome to Sweetgrass (Unit A), a light and airy first floor condo designed for comfort and simple living just steps from Spring Street. Ideal for up to four guests, this inviting home offers a casual Charleston...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 4
Bohemian Haven | Southern Shangri-La Sui...

Permit Number: 06322The Space: Welcome to Southern Shangri-La on Coming Street, a colorful top-floor getaway in the heart of downtown Charleston with casual island-inspired appeal!Apartment D offers about 700 square feet of bright, comfortable...

  • Charleston
  • 2 Bedrooms
  • 1 Bathrooms
  • Sleeps 4
Downtown Family-Friendly Home By Restaur...

Summary:Flora House occupies the top floor of a majestic Historic Charleston residence dating back to 1905. While thoughtfully modernized for modern living, it handsomely preserves the appeal of its origins, featuring original wood floors and...

  • Charleston
  • 4 Bedrooms
  • 2 Bathrooms
  • Sleeps 8
Occasionally Luxe | Girls Trip Dream Hom...

Summary:Welcome to Occasionally Luxe ✨ your home away from home in the heart of downtown Charleston! This 4BR/3BA getaway blends historic appeal with modern comfort. Just steps from King Street’s top stores, dining, and nightlife. Unwind in...

  • Charleston
  • 4 Bedrooms
  • 3 Bathrooms
  • Sleeps 8
Zuma Suite | Walk to King Street Shops!

Summary:Welcome to your modren escape, a thoughtfully designed getaway that blends clean modern interiors with comfortable appeal. Ideal for couples, solo travelers or modest groups, this property offers comfort, convenience and access to the very...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 5
Chic 2-bedroom corporate apt with riverv...

Get ready to relax in this impressive 2-bedroom corporate apartment in Historic Charleston. This condo features premium queen beds in each bedroom, two full bathrooms with showers and hair dryers, a comfortable living room with a couch, WiFi, AC, a...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 4
The Longshoreman | Neighboring The Cedar...

Permit Number: 07279The Space: Welcome to The Longshoreman, an handsome Charleston getaway set within a charmingly restored 1880s home where historic appeal meets modern comfort for a memorable stay!Bedrooms & Bathrooms• Cozy queen beds with high...

  • Charleston
  • 3 Bedrooms
  • 1 Bathrooms
  • Sleeps 6
In the Heart of King Street | Edisto Sui...

Permit Number: 004141The Space: Welcome to your second-floor getaway at iconic 493 King Street, set inside a striking historic building above Sewing Down South—featured on Southern Charm. Step outside and you’re instantly surrounded by...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 6
Urban Chic Living | Resi on Rutledge

Permit Number: 07181The Space: Welcome to Resi @ Rutledge, a peaceful and inviting getaway located along historic Rutledge Avenue in the heart of Charleston, offering a casual home base just mins. from the city’s most beloved sights!Bedrooms ...

  • Charleston
  • 2 Bedrooms
  • 1 Bathrooms
  • Sleeps 4
Dog-friendly home with AC, fireplace & W...

Summary:4 Tully AlleyThe Space:With Upper King Street's amazing dining and nightlife only one block away, this home is charmingly located for your next couples' trip or hideaway with friends near the heart of downtown Charleston. This home is...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 8
In the Heart of King Street! | Drayton S...

Permit Number: 004141The Space: Welcome to your home on historic 493 King Street, set on the second floor of a striking building above Sewing Down South—featured on Southern Charm. Step outside and you’re instantly surrounded by Charleston’s...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 6
Downtown Duplex - Rutledge Avenue

Feel the timeless appeal of Charleston’s historic peninsula, the Holy City. Stay just mins. from MUSC, the College of Charleston, and the vibrant shopping, dining, and nightlife of King Street. From this ideally located downtown home, you’ll be...

  • Charleston
  • 4 Bedrooms
  • 2 Bathrooms
  • Sleeps 12
Unique & Full of Charm! Parking + 1 bloc...

Summary:Welcome to The Parlor House, a one-of-a-kind Charleston getaway where historic architecture and modern luxury come together in the heart of downtown. Originally a Victorian-era storefront, this attractively restored residence has been...

  • Charleston
  • 3 Bedrooms
  • 3 Bathrooms
  • Sleeps 7
Newly Restored Historic Home, Close to K...

Welcome to 12 Cannon Street, Units A & B – a attractively restored four-bedroom, six-bathroom Charleston-style home in the heart of the city. This combined listing is ideal for bigger families and groups seeking modern amenities within walking...

  • Charleston
  • 4 Bedrooms
  • 6 Bathrooms
  • Sleeps 12