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Charleston, SC 2+ Bedroom Vacation Rentals

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1053 rentals found
Renovated Penthouse 4BR 4BA - Walk to Ki...

Feel the timeless appeal of Charleston’s historic peninsula, the Holy City. Stay just mins. from MUSC, the College of Charleston, and the vibrant shopping, dining, and nightlife of King Street. From this ideally located downtown home, you’ll be...

  • Charleston
  • 4 Bedrooms
  • 4 Bathrooms
  • Sleeps 12
Private Renovated 2BR Charleston Townhom...

Minimum Stay: 30 DaysThis newly refreshed two-bedroom, two-bath townhome offers a comfortable and private setting for extended stays in Charleston. Located in a peaceful community just mins. from downtown, MUSC, and local beaches, it provides the...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 5
Historic Neighborhood | The Newberry

Permit Number: 06840The Space: Feel the appeal of historic Charleston in this charmingly preserved first-floor apartment constructed in 1890 and located right in the heart of downtown!This cavernous 3-bedroom, 2-bath getaway blends classic character...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 6
Chic Downtown 2bd Retreat with Parking

Summary:Discover Charleston from our classy 2-BR top-floor apartment on Spring Street! Located in a historic Victorian home, this sun-filled getaway comfortably sleeps 4. Features a king bed, dedicated workspace, and a kitchenette. Savor modern...

  • Charleston
  • 2 Bedrooms
  • 1 Bathrooms
  • Sleeps 4
Downtown Luxury | Rutledge Avenue Inn (S...

Permit Number: 06814The Space: This opulent second-floor condo comfortably hosts up to four guests in Charleston’s sought-after Cannonborough–Elliotborough neighborhood on Rutledge Avenue, with painless parking and fast access to downtown...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 4
Charming home in West Ashley - 90% Remod...

*30 Nighttime Minimum Stay Requirement* **12% Discount for Monthly Units**Entirely Furnished / Executive Rental that has been 90% Remodeled. All new Kitchen Appliances, Granite Countertops, Tile backsplash, New Laminate Flooring, New Master Bath...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 5
Private Balcony • 2 Living Rooms • W...

Summary:✨ Welcome to Azaleas on Spring – Suite B! ????Notable amenities include:???? Balcony overlooking historic Spring St???? 2 Blocks to King St – Walk to Charleston’s Finest Dining, Shopping & Nightlife????️ Bonus second Living...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 8
Downtown Duplex - Rutledge Avenue

Feel the timeless appeal of Charleston’s historic peninsula, the Holy City. Stay just mins. from MUSC, the College of Charleston, and the vibrant shopping, dining, and nightlife of King Street. From this ideally located downtown home, you’ll be...

  • Charleston
  • 4 Bedrooms
  • 2 Bathrooms
  • Sleeps 12
Downtown CHS | King Beds Convert to Sing...

Summary:Welcome to Occasionally Luxe ✨ your home away from home in the heart of downtown Charleston! This 4BR/3BA getaway blends historic appeal with modern comfort. Just steps from King Street’s top stores, dining, and nightlife. Unwind in...

  • Charleston
  • 4 Bedrooms
  • 3 Bathrooms
  • Sleeps 8
Full House, Bikes, Grill + Patio, Walk E...

Summary:This home has everything you need for the ideal group trip to Charleston. Located in the heart of Downtown in a safe, beautiful neighborhood, The Rose features six gorgeously refreshed bedrooms, two full kitchens, and two roomy living areas...

  • Charleston
  • 6 Bedrooms
  • 4 Bathrooms
  • Sleeps 16
Private Quartiers in Downtown Charleston

Summary:The Quartiers Charlestonian are a blend of historic appeal and modern luxury featuring five queen bedrooms and three baths in which were thoughtfully refreshed. These adjoining historic suites provide a private stay, just steps away from the...

  • Charleston
  • 5 Bedrooms
  • 3 Bathrooms
  • Sleeps 10
4bd House Downtown w. Rooftop Terrace + ...

Summary:Feel Charleston from 'Palmetto on Spring | Penthouse,' a modernized 3-floor home in the striking Cannonborough neighborhood. Ideal for groups, this 4-bedroom, 4.5-bath getaway comfortably sleeps 10+ and features a private rooftop terrace and...

  • Charleston
  • 4 Bedrooms
  • 4 Bathrooms
  • Sleeps 10
Historic Condo Just Steps to Upper King ...

Summary:Welcome to this striking Charleston property! Featuring three comfortable bedrooms and two well-appointed bathrooms, this home is accentuated with vibrant green details that add a fresh and inviting touch. The open layout promotes natural...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 8
Downtown Modern - 4BR Spring St. Home w/...

Welcome to the Holy City, and the historic southern appeal of the Charleston peninsula. Our Vacation Rental By Owner is located in striking downtown Charleston and just mins. away from MUSC, the College of Charleston, and King Street’s shopping...

  • Charleston
  • 4 Bedrooms
  • 3 Bathrooms
  • Sleeps 11
Stylish, Dog-Friendly, 30-Day Rental Hou...

Summary:1168 Wyndham Rd - 30 Day RentalThe Space:Sneak away for a well-deserved change of scenery at this family-friendly home on James Island. Sunny and chic, the all-white interior of this striking vacation rental features a well-equipped, full...

  • Charleston
  • 3 Bedrooms
  • 1 Bathrooms
  • Sleeps 6
European Influences in the Heart of Char...

Summary:Ideal for a sizable family! Just three blocks away from upper King Street, the epicenter of the city's acclaimed restaurant and nightlife district. Our amazing city offers galleries, museums, elegant churches, great shopping, and the beach...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 8
The Philip's Suite, newly renovated 3 Be...

Welcome to the Philip's Suite (Unit B) at 183 Saint Philip Street, your freshly modernized Charleston haven 1 BLOCK from King Street! This new construction gem places you steps away from the city's vibrant attractions. Each bedroom features Serena ...

  • Charleston
  • 3 Bedrooms
  • 3 Bathrooms
  • Sleeps 8
Rantum Scoot of Downtown Charleston

Offered for the first time on Vacation Rental By Owner! This freshly remodeled completely furnished 3-bedroom, 2-bathroom gem offers a comfortable and convenient living experience. Located in a peaceful neighborhood just two blocks off the bustling...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 6