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Charleston, SC 2+ Bedroom Vacation Rentals

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1112 rentals found
The Neptune | Lofted Charm, Your Serene ...

Permit Number: 06320The Space: Ideal for:- Those who appreciate vibrant nightlife- Getaways with friends- Modest families- Food enthusiastsThis inviting three-bedroom home is just steps away from the lively nightlife on upper King Street. What sets...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 7
Historic Downtown Home w/ Parking
2.0
(1)

Welcome to the Holy City, and the historic southern appeal of the Charleston peninsula. Our Vacation Rental By Owner is located in impressive downtown Charleston and just mins. away from MUSC, the College of Charleston, and King Street’s shopping...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 10
Minutes away from Charleston and Beaches...

Welcome to Charleston y'all. You will adore staying at our colorfully decorated condo. This space is light, airy and bright. This is really a hidden gem located 1.5 miles from Charleston and a short walk to Avondale, our hipster town with plenty of...

  • Charleston
  • 2 Bedrooms
  • 1 Bathrooms
  • Sleeps 4
Downtown 2 bed, 2 bath, pet friendly apa...

******Please note this unit is for sale. Bumble Bee, one of Charleston's Finest, is a 2 bedroom 2 bath freshly refreshed apartment in the heart of historic downtown Charleston. It is available for units of 30 days or longer. It is the ideal home...

  • Charleston
  • 2 Bedrooms
  • 1 Bathrooms
  • Sleeps 4
Right Where You Need to Be! Centrally lo...

You can stop searching, this is the one! 3 Bedroom open concept home in the ideal location on James Island. 10 mins. to downtown Charleston, 10 mins. to Folly Beach and 30 mins. to the Airport. We have a sizable patio to appreciate your morning...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 6
Trendy Charleston 4BR - Steps from King ...
4.7
(23)

Summary:Beautiful 4BR/3BA home in Charleston's most charming neighborhood! ✰ Walker's Heaven! (Walk Score of 93)✰ King Street is Just 2 Blocks Away!✰ High-Speed WiFi & 3 Intelligent TVs ✰ Off-Street Parking This home is adjacent to a local...

  • Charleston
  • 4 Bedrooms
  • 3 Bathrooms
  • Sleeps 9
The Palmetto House- 3 Blocks To King Str...

Summary:Welcome to The Palmetto House - Your Charleston OasisEscape to the heart of Charleston and experience the ideal blend of comfort, convenience, and style at The Palmetto House. This striking 3-bedroom, 2-bath ground floor apartment is your...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 6
Magnolia House | Historic Charleston Hom...
4.6
(11)

Summary:Gather your group at this cavernous 6BR two-story Charleston style home that blends historic appeal with modern comfort. Just steps from King Street, appreciate eateries, stores, and nightlife at your doorstep. With two kitchens, dining...

  • Charleston
  • 6 Bedrooms
  • 3 Bathrooms
  • Sleeps 19
Charming 4-bedroom home, 10 Minutes to D...

Totally refreshed in 2025 -- Stay comfortably in Charleston at this 4-bedroom home. Each bedroom features a king bed, ensuring a pleasant nighttime's sleep for all guests. With amenities like a washing machine, WiFi, and AC, your stay will be both...

  • Charleston
  • 4 Bedrooms
  • 4 Bathrooms
  • Sleeps 8
30-Day Marshfront Rental Condo w/Amazing...

2436 Stono Watch - 30 Day RentalOur calendar is refreshed in real-time & our nightly prices are accurately displayed. Simply enter your desired dates and click 'Book Now!'Find an incredibly serene, marshfront setting at this two-bedroom condo on...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 4
The Manor | 8BR Home in Downtown Charles...

Summary:Feel Charleston in style at The Manor, an 8BR historic home in the heart of downtown. Ideal for huge groups, get-togethers, and celebrations, this modernized property blends timeless appeal with modern amenities. Walk to King Street’s...

  • Charleston
  • 8 Bedrooms
  • 4 Bathrooms
  • Sleeps 16
Pelican Hideaway - Charleston’s Most C...

Welcome to this enchanting 2-bedroom, 2-bathroom home in the highly beautiful Hampton Park neighborhood. Ideal for modest groups of friends or families, this comfortable getaway provides a warm and inviting ambiance. Unwind in the cavernous...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 6
Welcome to this adorable well maintained...

Ideal located home, 5 mins. from Folly and 10 mins. from downtown Charleston and MUSC. Home has been newly furnished; adore shown in all the details.This 1,864 square feet home is a calming space for the business professional or traveling...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 5
Dog-friendly home with AC, fireplace & W...
4.5
(30)

4 Tully Alley Our calendar is refreshed in real-time & our nightly prices are accurately displayed. Simply enter your desired dates and click 'Book Now!'With Upper King Street's magnificant dining and nightlife only one block away, this home is...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 8
Stunning, cozy, glamorous penthouse walk...

We're thrilled to share our unique living space with you, offering the ideal hideaway for an memorable vacation.Our property exudes a sense of warmth and coziness, but also fun & fantasy that will make you feel right at home. We've carefully curated...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 8
St. Tropez House | Historic 2-Story w/ C...
4.8
(94)

Summary:Welcome to our striking, Charleston-Style Home just steps from the famed King Street. • Walk Score 96 (most everything is in walking distance)• 5min commute by car to Market Street / Historic District• Entirely equipped + supplied...

  • Charleston
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 8
Charleston Charmer - House close to King...
4.9
(45)

Summary:Welcome to our striking 3 Bedroom/2.5 Bath historic home in the gorgeous Cannonborough/Elliotborough neighborhood! Constructed in 1840, this handsomely modernized home seamlessly blends its rich history with modern amenities. Immerse...

  • Charleston
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 8
Downtown 2 bedroom, sun-filled historic ...

**Charming 2-Bedroom Retreat with Modern Comforts!**Welcome to your home away from home! This attractively decorated 2-bedroom, 1-bath getaway features new appliances and a completely outfitted kitchen, including a Nespresso machine and everything...

  • Charleston
  • 2 Bedrooms
  • 1 Bathrooms
  • Sleeps 4